The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Intensive Care Unit Management of Patients with Severe Pulmonary Hypertension and Right Heart Failure
Abstract
Despite advances in medical therapies, pulmonary arterial hypertension (PAH) continues to cause significant morbidity and mortality. Although the right ventricle (RV) can adapt to an increase in afterload, progression of the pulmonary vasculopathy that characterizes PAH causes many patients to develop progressive right ventricular failure. Furthermore, acute right ventricular decompensation may develop from disorders that lead to either an acute increase in cardiac demand, such as sepsis, or to an increase in ventricular afterload, including interruptions in medical therapy, arrhythmia, or pulmonary embolism. The poor reserve of the right ventricle, RV ischemia, and adverse right ventricular influence on left ventricular filling may lead to a global reduction in oxygen delivery and multiorgan failure. There is a paucity of data to guide clinicians caring for acute right heart failure in PAH. Treatment recommendations are frequently based on animal models of acute right heart failure or case series in humans with other causes of pulmonary hypertension. Successful treatment often requires that invasive hemodynamics be used to monitor the effect of strategies that are based primarily on biological plausibility. Herein we have developed an approach based on the current understanding of RV failure in PAH and have attempted to develop a treatment paradigm based on physiological principles and available evidence.
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Cites
Updated clinical classification of pulmonary hypertension
Simonneau, G., Gatzoulis, M. A., Adatia, I., Celermajer, D., Denton, C., Ghofrani, A., Gomez Sanchez, M. A., Krishna Kumar, R., Landzberg, M., Machado, R. F., et al. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.10.029 · Cited by 4,191
Benza, R. L., Miller, D. P., Gomberg-Maitland, M., Frantz, R. P., Foreman, A. J., Coffey, C. S., Frost, A., Barst, R. J., Badesch, D. B., Elliott, C. G., et al. (2010) · Circulation · doi:10.1161/circulationaha.109.898122 · Cited by 1,547
Orens, J. B., Estenne, M., Arcasoy, S., Conte, J. V., Corris, P., Egan, J. J., Egan, T., Keshavjee, S., Knoop, C., Kotloff, R., et al. (2006) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2006.03.011 · Cited by 1,073
Tji-Joong Gan, C., Lankhaar, J.-W., Marcus, J. T., Westerhof, N., Marques, K. M., Bronzwaer, J. G. F., Boonstra, A., Postmus, P. E., & Vonk-Noordegraaf, A. (2006) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01031.2005 · Cited by 306
The importance of the gastrointestinal system in the pathogenesis of heart failure
Krack, A., Sharma, R., Figulla, H. R., & Anker, S. D. (2005) · European Heart Journal · doi:10.1093/eurheartj/ehi389 · Cited by 280
Cited by
2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension
Galiè, N., Humbert, M., Vachiery, J.-L., Gibbs, S., Lang, I., Torbicki, A., Simonneau, G., Peacock, A., Vonk Noordegraaf, A., Beghetti, M., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehv317 · Cited by 6,931
Self-citationHarjola, V.-P., Mebazaa, A., Čelutkienė, J., Bettex, D., Bueno, H., Chioncel, O., Crespo-Leiro, M. G., Falk, V., Filippatos, G., Gibbs, S., et al. (2016) · European Journal of Heart Failure · doi:10.1002/ejhf.478 · Cited by 720
Management of Pulmonary Arterial Hypertension
McLaughlin, V. V., Shah, S. J., Souza, R., & Humbert, M. (2015) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2015.03.540 · Cited by 366
Positive pressure ventilation in the cardiac intensive care unit
Alviar, C. L., Miller, P. E., McAreavey, D., Katz, J. N., Lee, B., Moriyama, B., Soble, J., van Diepen, S., Solomon, M. A., & Morrow, D. A. (2018) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2018.06.074 · Cited by 271
Hoeper, M. M., Benza, R. L., Corris, P., de Perrot, M., Fadel, E., Keogh, A. M., Kühn, C., Savale, L., & Klepetko, W. (2019) · European Respiratory Journal · doi:10.1183/13993003.01906-2018 · Cited by 216
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Metadata
- Authors
- Hoeper, M. M., & Granton, J.
- Venue
- American Journal of Respiratory and Critical Care Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2011-11-15
- Volume
- 184
- Issue
- 10
- Pages
- 1114-1124
- ISSN
- 1073-449X (ISSN-L)
- 1535-4970
- OpenAlex
- W2086023854
- Cited by
- 316
- References
- 5
- FWCI
- 13.11
- Type
- journal article
- Language
- en
- Open access
- closed
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- Hoeper, M. M., & Granton, J. (2011). Intensive Care Unit Management of Patients with Severe Pulmonary Hypertension and Right Heart Failure. American Journal of Respiratory and Critical Care Medicine. https://doi.org/10.1164/rccm.201104-0662ci
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
