Cited by 320Cystic Fibrosis Research AdvancesBacterial biofilms and quorum sensingGut microbiota and health

The DOI matches its Crossref record; 62 of the 62 references it cites were found in a registry or an index.

Lung Microbiota and Bacterial Abundance in Patients with Bronchiectasis when Clinically Stable and during Exacerbation

Open access

Tunney, Michael M., Einarsson, Gisli G., Wei, Lan, Drain, Maire, Klem, Erich R., Cardwell, Chris, Ennis, Madeleine, Boucher, Richard C., Wolfgang, Matthew C., Elborn, J. Stuart·2013·American Journal of Respiratory and Critical Care Medicine

DOI 10.1164/rccm.201210-1937ocPMC PMC3734618

Open this paper in CoChat — free account

Abstract

RATIONALE: Characterization of bacterial populations in infectious respiratory diseases will provide improved understanding of the relationship between the lung microbiota, disease pathogenesis, and treatment outcomes. OBJECTIVES: To comprehensively define lung microbiota composition during stable disease and exacerbation in patients with bronchiectasis. METHODS: Sputum was collected from patients when clinically stable and before and after completion of antibiotic treatment of exacerbations. Bacterial abundance and community composition were analyzed using anaerobic culture and 16S rDNA pyrosequencing. MEASUREMENTS AND MAIN RESULTS: In clinically stable patients, aerobic and anaerobic bacteria were detected in 40 of 40 (100%) and 33 of 40 (83%) sputum samples, respectively. The dominant organisms cultured were Pseudomonas aeruginosa (n = 10 patients), Haemophilus influenzae (n = 12), Prevotella (n = 18), and Veillonella (n = 13). Pyrosequencing generated more than 150,000 sequences, representing 113 distinct microbial taxa; the majority of observed community richness resulted from taxa present in low abundance with similar patterns of phyla distribution in clinically stable patients and patients at the onset of exacerbation. After treatment of exacerbation, there was no change in total (P = 0.925), aerobic (P = 0.917), or anaerobic (P = 0.683) load and only a limited shift in community composition. Agreement for detection of bacteria by culture and pyrosequencing was good for aerobic bacteria such as P. aeruginosa (κ = 0.84) but poorer for other genera including anaerobes. Lack of agreement was largely due to bacteria being detected by pyrosequencing but not by culture. CONCLUSIONS: A complex microbiota is present in the lungs of patients with bronchiectasis and remains stable through treatment of exacerbations, suggesting that changes in microbiota composition do not account for exacerbations.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1164/rccm.201210-1937oc

Cites

62 of 62 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Global Initiative for Chronic Obstructive Lung Disease
Gerald, L. B., & Bailey, W. C. (2002) · Journal of Cardiopulmonary Rehabilitation · doi:10.1097/00008483-200207000-00004 · Cited by 5,806
The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease
Hogg, J. C., Chu, F. S. F., Utokaparch, S., Woods, R. R., Elliott, W. M., Buzatu, L., Cherniack, R. M., Rogers, R. M., Sciurba, F. C., Coxson, H. O., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa032158 · Cited by 3,828
Disordered Microbial Communities in Asthmatic Airways
Hilty, M., Burke, C. M., Pedro, H., Cárdenas, P., Bush, A., Bossley, C. J., Davies, J. C., Ervine, A., Poulter, L. W., Pachter, L. S., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0008578 · Cited by 1,874
Effect of Aerosolized Recombinant Human DNase on Exacerbations of Respiratory Symptoms and on Pulmonary Function in Patients with Cystic Fibrosis
Fuchs, H. J., Borowitz, D., Christiansen, D. H., Morris, E. M., Nash, M. L., Ramsey, B. W., Rosenstein, B. J., Smith, A. L., & Wohl, M. E. B. (1994) · New England Journal of Medicine · doi:10.1056/nejm199409083311003 · Cited by 1,532
Intermittent Administration of Inhaled Tobramycin in Patients with Cystic Fibrosis
Ramsey, B. W., PEPE, M. S., Quan, J. M., Otto, K., Montgomery, A. B., Williams‐Warren, J., Vasiljev-K, M., Borowitz, D., Bowman, C. M., Marshall, B. C., et al. (1999) · New England Journal of Medicine · doi:10.1056/nejm199901073400104 · Cited by 1,296
Infection in the Pathogenesis and Course of Chronic Obstructive Pulmonary Disease
Sethi, S., & Murphy, T. F. (2008) · New England Journal of Medicine · doi:10.1056/nejmra0800353 · Cited by 1,238
Topographical Continuity of Bacterial Populations in the Healthy Human Respiratory Tract
Charlson, E. S., Bittinger, K., Haas, A. R., Fitzgerald, A. S., Frank, I., Yadav, A., Bushman, F. D., & Collman, R. G. (2011) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201104-0655oc · Cited by 1,144
British Thoracic Society guideline for non-CFbronchiectasis
Pasteur, M. C., Bilton, D., Hill, A. T., & on behalf of the British Thoracic Society Bronchiectasis (non-CF) Guideline Group (2010) · Thorax · doi:10.1136/thx.2010.136119 · Cited by 1,043
Analysis of the lung microbiome in the “healthy” smoker and in COPD.
Erb-Downward, J. R., Thompson, D. L., Han, M. K., Freeman, C. M., McCloskey, L., Schmidt, L. A., Young, V. B., Toews, G. B., Curtis, J. L., Sundaram, B., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0016384 · Cited by 973 · cited 6×
“For example, genomic differences have been shown to be associated with the ability of H. influenzae strains to cause exacerbations of COPD (51).”
BackgroundResultInfluential
Mechanisms of Action and Clinical Application of Macrolides as Immunomodulatory Medications
Kanoh, S., & Rubin, B. K. (2010) · Clinical Microbiology Reviews · doi:10.1128/cmr.00078-09 · Cited by 722

Flagged first, then by citations

Show all 62 references

Research works printed but not linked: 1

Einarsson, 2011, Microbial community composition in the lungs of patients with cystic fibrosis and non-CF bronchiectasis [abstract], Thorax, 66, A48

Sorted by citations

Items 201–300 of 320

Pathophysiology
Boaventura, R. D. P., Shoemark, A., & Chalmers, J. D. (2018) · European Respiratory Society eBooks · doi:10.1183/2312508x.10021218 · Cited by 7
Enrichment of human nasopharyngeal bacteriome with bacteria from dust after short-term exposure to indoor environment: a pilot study
Konecna, E., Videnska, P., Burešová, L., Urík, M., Smetanová, S., Smatana, S., Prokeš, R., Lanickova, B., Budínská, E., Klánová, J., et al. (2023) · BMC Microbiology · doi:10.1186/s12866-023-02951-5 · Cited by 9
Bronchiectasis: the arrival of better evidence
Goyal, V., Grimwood, K., & Chang, A. B. (2013) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(13)70246-7 · Cited by 7
Techniques: culture, identification and 16S rRNA gene sequencing
Einarsson, G. G., & Boutin, S. (2019) · European Respiratory Society eBooks · doi:10.1183/2312508x.10000819 · Cited by 6
Self-citation
Potential clinical utility of multiple target quantitative polymerase chain reaction (qPCR) array to detect microbial pathogens in patients with chronic obstructive pulmonary disease (COPD)
O’Farrell, H. E., Shaw, J. G., Goh, F., Bowman, R., Fong, K. M., Krause, L., & Yang, I. A. (2019) · Journal of Thoracic Disease · doi:10.21037/jtd.2019.10.39 · Cited by 5
Infection prevention and chronic disease management in cystic fibrosis and noncystic fibrosis bronchiectasis
Lommatzsch, S. T. (2020) · Therapeutic Advances in Respiratory Disease · doi:10.1177/1753466620905272 · Cited by 6
Pharmacotherapeutic management of bronchial infections in adults: non-cystic fibrosis bronchiectasis and chronic obstructive pulmonary disease
Pasquale, M. D., Aliberti, S., Mantero, M., Gramegna, A., & Blasi, F. (2020) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2020.1793958 · Cited by 6
Mycobacterium avium Complex and Bronchiectasis. There’s Something Happening Here..
Griffith, D. E., & Aksamit, T. R. (2018) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201807-1243ed · Cited by 6
Lung microbiome alterations in patients with anti-Jo1 antisynthetase syndrome and interstitial lung disease
Quintero-Puerta, T., Lira-Lucio, J. A., Falfán‐Valencia, R., Vega-Sánchez, Á. E., Márquez-García, E., Mejía, M. E., Bautista-Becerril, B., Rojas‐Serrano, J., Ramos-Martı́nez, E., Buendía-Roldán, I., et al. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1321315 · Cited by 6
Bronchiectasis
O’Donnell, A. E. (2015) · Current Opinion in Pulmonary Medicine · doi:10.1097/mcp.0000000000000152 · Cited by 5
Self-management for non-cystic fibrosis bronchiectasis
Kelly, C., Spencer, S., Grundy, S., Lynes, D., & Evans, D. J. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012528 · Cited by 5
Bronchiectasis: What We Don't Know Yet But Should
Hester, K. L. M., McDonnell, M. J., & Soyza, A. D. (2016) · Barcelona Respiratory Network · doi:10.23866/brnrev:2016-0013 · Cited by 5
A truncated mutation of MucA in Pseudomonas aeruginosa from a bronchiectasis patient affects T3SS expression and inflammasome activation
Liu, Y., Du, L., Zhu, Y., Liu, X., Zhou, N., Li, C., Li, Q., & He, P. (2022) · Acta Biochimica et Biophysica Sinica · doi:10.3724/abbs.2022169 · Cited by 5
Molecular identification and genotyping of Pseudomonas aeruginosa isolated from cystic fibrosis and non-cystic fibrosis patients with bronchiectasis
Eusébio, N., Amorim, A. A., Gamboa, F., & Araújo, R. (2014) · Pathogens and Disease · doi:10.1093/femspd/ftu014 · Cited by 5
The Lung Microbiome in Carcinogenesis and Immunotherapy Treatment
Kennedy, K. J., Khaddour, K., Ramnath, N., & Weinberg, F. D. (2023) · The Cancer Journal · doi:10.1097/ppo.0000000000000644 · Cited by 5
Update in Sepsis and Pulmonary Infections 2013
Wunderink, R. G., & Walley, K. R. (2014) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201403-0577up · Cited by 5
Non-cystic fibrosis bronchiectasis: The long road to multidrug resistant bacteria
Menéndez, R., Sahuquillo-Arce, J. M., Méndez, R., & Hernández-Cabezas, A. (2016) · Community Acquired Infection · doi:10.4103/2225-6482.198491 · Cited by 5
Long-Term Antibiotics in Bronchiectasis
Suárez-Cuartín, G., Hernandez-Argudo, M., Perea, L., & Sibila, O. (2021) · Seminars in Respiratory and Critical Care Medicine · doi:10.1055/s-0041-1730945 · Cited by 4
Lower airway dysbiosis in nontuberculous mycobacteria–positive bronchiectasis is associated with neutrophil extracellular trap–predominant severe phenotypes
Singh, S., Darawshy, F., Erlandson, K., Narayana, J. K., Li, Q., Li, Y., Atandi, I., Krolikowski, K., Patel, S., Collazo, D., et al. (2026) · American Journal of Respiratory and Critical Care Medicine · doi:10.1093/ajrccm/aamag015 · Cited by 4
Future directions: the next 10 years in research
Chotirmall, S. H. (2018) · European Respiratory Society eBooks · doi:10.1183/2312508x.10017217 · Cited by 5
Changes in sputum microbiota during treatment for nontuberculous mycobacterial pulmonary disease
Kim, B., Yu, J. Y., Kim, S., Kim, D. H., & Jhun, B. W. (2023) · Scientific Reports · doi:10.1038/s41598-023-47230-5 · Cited by 4
Microbiota in the pathogenesis of COPD and its impact on the course of the disease
Fedotov, V. D., Zhestkov, A. V., Lyamin, A. V., Zaslavskaya, M. I., Сергеевна, Д. И., & TULICHEV, A. A. (2022) · Clinical Microbiology and Antimicrobial Chemotherapy · doi:10.36488/cmac.2022.3.202-212 · Cited by 5
Evolution of nucleic acid extraction methods and its role in development of complex human diagnostic solutions with special reference to tuberculosis: A review
Goyani, K. H., & Mukhopadhyaya, P. N. (2023) · Magna Scientia Advanced Research and Reviews · doi:10.30574/msarr.2023.9.2.0166 · Cited by 4
Microbiome in Chronic Lung Diseases
Mammen, M. J., & Sethi, S. (2017) · Barcelona Respiratory Network · doi:10.24875/brn.m17000010 · Cited by 4
Mikrobiom układu oddechowego
Górecka, D., Nowiński, A., & AUGUSTYNOWICZ-KOPEĆ, E. M. (2014) · Advances in respiratory medicine · doi:10.5603/piap.2014.0063 · Cited by 4
The overlap with bronchiectasis
Martínez‐García, M. Á., Carro, L. M., & de la Rosa, D. (2015) · European Respiratory Society eBooks · doi:10.1183/2312508x.10018314 · Cited by 4
Bronchiectasis
Chan, E. D., & Iseman, M. D. (2015) · Elsevier eBooks · doi:10.1016/b978-1-4557-3383-5.00048-8 · Cited by 4
Bacterial Isolates from Bronchoalveolar Lavage in Pediatric Patients with Protracted Bacterial Bronchitis or Bronchiectasis: A Retrospective Comparative Study
Moriki, D., Tsouprou, M., Prountzos, S., Koumpagioti, D., Kalogiannis, M., Alexopoulou, E., & Douros, K. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14217653 · Cited by 3
Exploring the Association of Bacterial Coinfections with Clinical Characteristics of Patients with Nontuberculous Mycobacterial Pulmonary Disease
Moon, S. M., Cho, H., & Shin, B. (2024) · Tuberculosis & respiratory diseases · doi:10.4046/trd.2024.0003 · Cited by 3
Risk factors for readmission within one year after acute exacerbations of bronchiectasis in a Chinese tertiary hospital: a retrospective cohort study
Fan, Y., Su, Y., Zhang, H., Yang, X., Zhang, Z., Zhang, S., Zhang, S.-X., Wu, D., Zheng, P., Lu, Z., et al. (2024) · BMC Pulmonary Medicine · doi:10.1186/s12890-024-03402-1 · Cited by 3
Bronchiectasis: What We Don’t Know Yet But Should
Soyza, A. D., Hester, K. L. M., & McDonnell, M. J. (2016) · Barcelona Respiratory Network · doi:10.23866/brnrev:2016-m0013 · Cited by 3
The Microbiome at Other Mucosal Sites
Cárdenas, P., & Cookson, W. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-415847-4.00006-9 · Cited by 4
Berkjuskúlk - yfirlit
Guðmundsson, G., & Juliusson, G. (2020) · Læknablaðið · doi:10.17992/lbl.2020.0708.592 · Cited by 3
Bronchiectasis in adults: epidemiology, assessment of severity and prognosis
Chalmers, J. D. (2015) · Current Pulmonology Reports · doi:10.1007/s13665-015-0120-x · Cited by 3
Pseudomonas aeruginosa and Bronchiectasis
Soyza, A. D., & Winstanley, C. (2017) · Springer eBooks · doi:10.1007/978-3-319-61452-6_12 · Cited by 3
BRONCHOECTATIC DISEASE IN CHILDREN
Stepanov, А. А., Badalyan, A. R., & Melnikova, A. O. (2018) · Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) · doi:10.21508/1027-4065-2018-63-5-29-35 · Cited by 3
Bronchitis, Bronchiectasis
Butler, M. W., & Keane, M. P. (2016) · Elsevier eBooks · doi:10.1016/b978-0-7020-6285-8.00027-7 · Cited by 3
Airway total bacterial density, microbiota community composition and relationship with clinical parameters in bronchiectasis
Alfahl, Z., Einarsson, G. G., Elborn, J. S., Gilpin, D. F., O’Neill, K., Ferguson, K., Hill, A. T., Loebinger, M. R., Carroll, M., Gatheral, T. L., et al. (2024) · Respiratory Medicine · doi:10.1016/j.rmed.2024.107906 · Cited by 2
Self-citation
Inflammatory Phenotypes of Bronchiectasis
Koukaki, E., Papaiakovou, G., Klironomou, A., Theofani, E., Matthaiou, A. Μ., Liapikou, A., Anagnostopoulos, N., Stratakos, G. K., Bakakos, P., & Rovina, N. (2025) · Journal of Personalized Medicine · doi:10.3390/jpm15100499 · Cited by 2
Clinical and prognostic characteristics of stable bronchiectasis in adults with chronic Pseudomonas aeruginosa infection: a prospective cohort study
Zhou, R., Zhang, S.-Y., Su, Y., Chen, T., Xu, X., Chen, Y.-X., Zhang, Z., Wu, D., Lu, Z., & Qiu, L. (2026) · BMC Pulmonary Medicine · doi:10.1186/s12890-026-04145-x · Cited by 2
Epidemiological insights into Haemophilus influenzae and Pseudomonas aeruginosa persistent colonization in non-cystic fibrosis bronchiectasis patients: a longitudinal and multicenter study
Cadenas-Jiménez, I., Camps-Massa, P., Gonçalves-Carvalho, F., Benaali-Bakkar, Y., Quero, S., Rodríguez-Pons, L., Antuori, A., Saiz-Escobedo, L., Calvo-Silveria, S., Oliver, A., et al. (2026) · Respiratory Research · doi:10.1186/s12931-026-03553-1 · Cited by 2
Respiratory pathogens in patients with acute exacerbation of non-cystic fibrosis bronchiectasis from a developing country
Shahid, S., Jabeen, K., Iqbal, N., Farooqi, J. Q., & Irfan, M. (2021) · Monaldi Archives for Chest Disease · doi:10.4081/monaldi.2021.1771 · Cited by 2
Bronchiectasis
Aogáin, M. M., Chalmers, J. D., & Chotirmall, S. H. (2022) · Respiratory medicine · doi:10.1007/978-3-030-87104-8_7 · Cited by 2
Exploratory Bronchoalveolar Lavage Fluid Analyses Reveal a High Diversity of Microbiome in NTM Lung Disease and a Low Diversity of Microbiome in Bronchiectasis
Fujita, K., Yamamoto, Y., Kamita, M., Tanaka, K., Nakabayashi, T., Imakita, T., Oi, I., Kanai, O., Mio, T., Tanizawa, K., et al. (2024) · Open Respiratory Archives · doi:10.1016/j.opresp.2024.100351 · Cited by 2
Screening for primary immune deficiency among patients with bronchiectasis
Dufrénoy, M., Luca, L., Bironneau, V., Meurice, J.-C., Puyade, M., & Martin, M. (2024) · La Revue de Médecine Interne · doi:10.1016/j.revmed.2024.06.010 · Cited by 2
Pseudomonas aeruginosa mucinous phenotypes and algUmucABD operon mutant characteristics obtained from inpatients with bronchiectasis and their correlation with acute aggravation
Tan, Y., & Dai, Z. (2024) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2024.1402348 · Cited by 2
Retracted
Assessing the Airway Microbiota in Cystic Fibrosis
Hoppe, J. E., Harris, J. K., & Zemanick, E. T. (2016) · Clinical Microbiology Newsletter · doi:10.1016/j.clinmicnews.2016.10.004 · Cited by 2
Microbiome in Chronic Lung Diseases
Mammen, M. J., & Sethi, S. (2017) · Barcelona Respiratory Network · doi:10.23866/brnrev:2017-m0042 · Cited by 5
Long-Term Inhaled Antibiotic Treatment in Bronchiectasis
Shteinberg, M., Johnson, C. B., & HAWORTH, C. S. (2017) · Springer eBooks · doi:10.1007/978-3-319-61452-6_16 · Cited by 2
OUTCOMES OF THE LONG-TERM ADMINISTRATION OF MACROLIDE ANTIBIOTICS IN CHILDREN WITH BRONCHIECTASES: FREQUENTLY ASKED QUESTIONS
Lazareva, N. B., Ших, Е. В., & Rebrova, E. V. (2018) · Вопросы современной педиатрии · doi:10.15690/vsp.v17i2.1884 · Cited by 2
Bronchiectasis Exacerbations: Clinical Relevance and Management
Mendes, M. A., Shoemark, A., & Chalmers, J. (2018) · Barcelona Respiratory Network · doi:10.23866/brnrev:2017-0016 · Cited by 1
Bacterial infection
Provost, K. A., Frederick, C. A., & Sethi, S. (2017) · European Respiratory Society eBooks · doi:10.1183/2312508x.10016216 · Cited by 2
Variable Ventilation from Bench to Bedside
Huhle, R., Pelosi, P. P., & de Abreu, M. G. (2016) · Annual update in intensive care and emergency medicine · doi:10.1007/978-3-319-27349-5_23 · Cited by 2
Navigating the microbial community in the trachea-oropharynx of breast cancer patients with or without neoadjuvant chemotherapy (NAC) via endotracheal tube: has NAC caused any change?
Kim, H. Y., Kim, T. H., Shin, J. H., Cho, K., Ha, H.-K., Lee, A., & Kim, Y. J. (2023) · PeerJ · doi:10.7717/peerj.16366 · Cited by 2
Pathophysiology, Immunology, and Histopathology of Bronchiectasis
Menéndez, R., & Sibila, O. (2017) · Springer eBooks · doi:10.1007/978-3-319-61452-6_5 · Cited by 2
Sputum purulence-associated microbial community compositions in adults with bronchiectasis
Guan, W., Huang, Y., Chen, C.-L., Yuan, J.-J., Li, H., Gao, Y., Chen, R., & Zhong, N. (2018) · Journal of Thoracic Disease · doi:10.21037/jtd.2018.08.30 · Cited by 2
Disbiosis microbiana en las bronquiectasias y la fibrosis quística
Dicker, A., & Chalmers, J. D. (2017) · Archivos de Bronconeumología · doi:10.1016/j.arbres.2016.11.018 · Cited by 2
Exact Tests of Zero Variance Component in Presence of Multiple Variance Components with Application to Longitudinal Microbiome StudyPreprint
Zhai, J., Knox, K. S., Twigg, H. L., Zhou, H., & Zhou, J. J. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/281246 · Cited by 2
Bronchiectasis in renal transplant patients: a cross-sectional study
Mulette, P., Perotin, J., Muggeo, A., Guillard, T., Brisebarre, A., Meyer, H., Hagenburg, J., Ancel, J., Dormoy, V., Vuiblet, V., et al. (2024) · European journal of medical research · doi:10.1186/s40001-024-01701-1 · Cited by 1
Analysis of pulmonary microecology and clinical characteristics of patients carrying human herpesvirus
Luo, J., Xie, R., Bao, C., Lin, J., Xu, Y., Yan, X., Yang, Z., Feng, L., Wu, J., Chen, D., et al. (2024) · Future Microbiology · doi:10.1080/17460913.2024.2357994 · Cited by 1
Insights into human respiratory microbiome under dysbiosis and its analysis tool
Helal, M., & Bari, V. K. (2025) · Frontiers in Microbiomes · doi:10.3389/frmbi.2025.1549166 · Cited by 1
Inhaled antibiotics for bronchiectasis: are we there yet?
Johnson, C. B., & HAWORTH, C. S. (2015) · Current Pulmonology Reports · doi:10.1007/s13665-015-0126-4 · Cited by 1
Republished: Respiratory microbiota: addressing clinical questions, informing clinical practice
Rogers, G. B., Shaw, D. E., Marsh, R. L., Carroll, M. P., Serisier, D. J., & Bruce, K. D. (2015) · Postgraduate Medical Journal · doi:10.1136/postgradmedj-2014-205826rep · Cited by 1
The Role of Other Bacteria, Fungi, and Viruses in Bronchiectasis
O’Donnell, A. E. (2017) · Springer eBooks · doi:10.1007/978-3-319-61452-6_13 · Cited by 1
Systemic and connective tissue diseases
Soyza, A. D. (2018) · European Respiratory Society eBooks · doi:10.1183/2312508x.10016517 · Cited by 1
Orangutan Respiratory Disease Syndrome
Lung, N. P., & Taylor‐Cousar, J. L. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-82852-9.00099-x · Cited by 1
Respiratory Pathogens at Exacerbation in Chronic Bronchitis With Airway Bacterial Colonisation: A Cohort Study
Jones, T. L., Roberts, C., Elliott, S., Glaysher, S., Green, B., Shute, J. K., & Chauhan, A. (2024) · The Clinical Respiratory Journal · doi:10.1111/crj.13811 · Cited by 1
Review of the British Thoracic Society Winter Meeting 2013, 4–6 December, London, UK
Chalmers, J. D., Greening, N. J., José, R. J. P., & Janes, S. M. (2014) · Thorax · doi:10.1136/thoraxjnl-2014-205177 · Cited by 1
Microbial Dysbiosis in Bronchiectasis and Cystic Fibrosis
Dicker, A., & Chalmers, J. D. (2017) · Archivos de Bronconeumología · doi:10.1016/j.arbr.2017.01.010 · Cited by 1
Primary Sclerosing Cholangitis
Bergasa, N. V. (2021) · Springer eBooks · doi:10.1007/978-1-4471-4715-2_5 · Cited by 1
Identification and Genotyping of Pseudomonas aeruginosa in Bronchiectasis
Eusébio, N. (2013) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) · doi:10.34626/r8g6-8q26 · Cited by 1
PULMONARY, SLEEP, AND CRITICAL CARE UPDATE Update in Sepsis and Pulmonary Infections 2013
Wunderink, R. G., & Walley, K. R. (2014)
Aspectos microbiológicos emergentes
Cantón, R., Blanco‐Aparicio, M., & Caballero, J. D. D. (2016) · Monografías de Archivos de Bronconeumología
Diagnóstico y manejo de las agudizaciones de bronquiectasias
Suárez-Cuartín, G., Polverino, E., & Sibila, O. (2016) · Monografías de Archivos de Bronconeumología
Non-cystic fibrosis bronchiectasis
Harrison, M., & HAWORTH, C. S. (2017) · European Respiratory Society eBooks · doi:10.1183/2312508x.10016716
Non-cystic fibrosis bronchiectasis
Finch, S., Dicker, A., & Chalmers, J. (2017) · European Respiratory Society eBooks · doi:10.1183/2312508x.10015816
Bronquiectasias y microorganismos multirresistentes: ¿el nicho ideal?
Méndez, R., Amara‐Elori, I., & Menéndez, R. (2018) · Archivos de Bronconeumología · doi:10.1016/j.arbres.2018.02.018
Bronchiectasis and Multidrug-resistant Microorganisms: The Ideal Niche?
Méndez, R., Amara‐Elori, I., & Menéndez, R. (2018) · Archivos de Bronconeumología · doi:10.1016/j.arbr.2018.02.028
FACTORS AFFECTING MORTALITY AND MORBIDITY IN PATIENTS WITH BRONCHIECTASIS
Özyürek, B. A., Bozbaş, Ş. S., Yılmaz, E. B., Ulubay, G., Akçay, Ş., & Eyüboğlu, F. Ö. (2019) · Kocatepe tıp dergisi. · doi:10.18229/kocatepetip.422758
The bronchiectasis microbiome
Rogers, G. B. (2018) · European Respiratory Society eBooks · doi:10.1183/2312508x.10015617
Totally antibiotic resistance Pseudomonas aeruginosa isolated from patients with blood stream infection
Hussein, A. M., Taha, Z. B., Malik, A. G., Hazim, D. K., Ahmed, R. J., Mohammed, O. B., Rasul, K. A., Bazaz, S., & Rashid, D. (2021) · Applied Nanoscience · doi:10.1007/s13204-021-02050-9
Microbiome and Inflammation in Antibody Deficiency
Berbers, R.-M. (2021) · Utrecht University Repository (Utrecht University) · doi:10.33540/254
The Respiratory Microbiome in Health and Disease
Invernizzi, R., & Molyneaux, P. L. (2021) · Elsevier eBooks · doi:10.1016/b978-0-08-102723-3.00196-7
Lung Diseases: Chronic Respiratory Infections
Blasi, F. (2018) · MDPI eBooks · doi:10.3390/books978-3-03897-339-3
A Study of Microbiological Profile and Sensitivity Pattern in Patients with Exacerbation of Bronchiectasis in a Tertiary Care Hospital
Deb, J., Ray, P., Mondal, P., Dwari, A. K., & Majumdar, A. K. (2022) · International Journal of Current Microbiology and Applied Sciences · doi:10.20546/ijcmas.2022.1102.022
Comparison of different conditions for DNA extraction in sputum - a pilot study
Oriano, M., Terranova, L., Teri, A., Sottotetti, S., Ruggiero, L., Tafuro, C., Marchisio, P., Gramegna, A., Amati, F., Nava, F., et al. (2019) · Multidisciplinary Respiratory Medicine · doi:10.4081/mrm.2019.4
Review of the British Thoracic Society Winter Meeting 2015, 2–4 December, London, UK
José, R. J. P., Chalmers, J. D., Greening, N. J., & Janes, S. M. (2016) · Thorax · doi:10.1136/thoraxjnl-2016-208299
Bronchiectasis
Hill, A. T. (2018) · Springer eBooks · doi:10.1007/978-3-319-94127-1_11
Faculty Opinions recommendation of Inhaled colistin in patients with bronchiectasis and chronic Pseudomonas aeruginosa infection.
Metersky, M. L. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.718310795.793557658
Inhalation of antibiotics in the treatment of bronchopulmonal infection
Gembitskaya, T. E., Анатольевич, Х. М., Chermensky, A. G., Chugunov, A. A., Kitsyshin, V. P., & Zdybko, A. S. (2022) · Bulletin of the Russian Military Medical Academy · doi:10.17816/brmma104883
The Microbiome in Critically Ill Patients
Tulli, G., & Zuanetti, G. (2022) · Springer eBooks · doi:10.1007/978-3-031-14612-1_7
Endobronchial optical coherence tomography or computed tomography for evaluating progression of bronchiectasis
Cheng, L., Guan, W., Zhong, C., Duan, C., Su, Z., Li, S., & Zhong, N. S. (2023) · ERJ Open Research · doi:10.1183/23120541.00490-2022
Development of a clinically feasible translational medical approaches in the treatment of Pseudomonas aeruginosa and Acinetobacter baumannii persistent biofilm infections.
Wannigama, D. L., Chatsuwan, T., Hurst, C. P., & Monk, P. (2019) · Chula Digiverse · doi:10.58837/chula.the.2019.364
Bronchiectasis
Saha, S., Majumdar, S., & Bhattacharyya, P. (2023) · Springer eBooks · doi:10.1007/978-981-99-3505-5_5
Unravelling the “frequent exacerbator” phenotype in cystic fibrosis
Cohen, R., & Shteinberg, M. (2024) · European Respiratory Journal · doi:10.1183/13993003.00068-2024
Additional file 8 of Enrichment of human nasopharyngeal bacteriome with bacteria from dust after short-term exposure to indoor environment: a pilot study
Konecna, E., Videnska, P., Burešová, L., Urík, M., Smetanová, S., Smatana, S., Prokeš, R., Lanickova, B., Budínská, E., Klánová, J., et al. (2023) · Figshare · doi:10.6084/m9.figshare.23812569
Additional file 3 of Enrichment of human nasopharyngeal bacteriome with bacteria from dust after short-term exposure to indoor environment: a pilot study
Konecna, E., Videnska, P., Burešová, L., Urík, M., Smetanová, S., Smatana, S., Prokeš, R., Lanickova, B., Budínská, E., Klánová, J., et al. (2023) · Figshare · doi:10.6084/m9.figshare.23812554
Additional file 2 of Enrichment of human nasopharyngeal bacteriome with bacteria from dust after short-term exposure to indoor environment: a pilot study
Konecna, E., Videnska, P., Burešová, L., Urík, M., Smetanová, S., Smatana, S., Prokeš, R., Lanickova, B., Budínská, E., Klánová, J., et al. (2023) · Figshare · doi:10.6084/m9.figshare.23812551
Additional file 5 of Enrichment of human nasopharyngeal bacteriome with bacteria from dust after short-term exposure to indoor environment: a pilot study
Konecna, E., Videnska, P., Burešová, L., Urík, M., Smetanová, S., Smatana, S., Prokeš, R., Lanickova, B., Budínská, E., Klánová, J., et al. (2023) · Figshare · doi:10.6084/m9.figshare.23812560
Microbiomes without boundaries: cystic fibrosis ‘pulmotype’ classifications are dependent on algorithm choice and database size, and indicate continuous variationPreprint
Zhao, C., Lowhorn, R. J., Song, H., Eum, J., & Brown, S. P. (2025) · medRxiv · doi:10.1101/2025.05.07.25326893

Authors: Tunney, M. M., Einarsson, G. G., Wei, L., Drain, M., Klem, E. R., Cardwell, C., Ennis, M., Boucher, R. C., Wolfgang, M. C., & Elborn, J. S.
Affiliations: Cystic Fibrosis and Airways Microbiology Research Group
Centre for Infection and Immunity, School of Medicine, Dentistry, and Biomedical Sciences, Queen’s University Belfast, Belfast, United Kingdom
University of North Carolina at Chapel Hill (US)
Queen's University Belfast (GB)
Corresponding author: Tunney, Michael M.
ORCID: Tunney, Michael M.
Einarsson, Gisli G.
Wei, Lan
Cardwell, Chris
Ennis, Madeleine
Boucher, Richard C.
Wolfgang, Matthew C.
Elborn, J. Stuart
Venue: American Journal of Respiratory and Critical Care Medicine
Publisher: Oxford University Press (OUP)
Published: 2013-05
Volume: 187
Issue: 10
Pages: 1118-1126
ISSN: 1073-449X (ISSN-L)
1535-4970
DOI: 10.1164/rccm.201210-1937oc
PMC: PMC3734618
OpenAlex: W2116345416
Cited by: 316
References: 62
Citations by year: 2026: 9 · 2025: 11 · 2024: 25 · 2023: 21 · 2022: 20 · 2021: 22 · 2020: 18 · 2019: 24 · 2018: 37 · 2017: 35 · 2016: 31 · 2015: 26 · 2014: 31 · 2013: 6
FWCI: 25.52
Type: journal article
Language: en
Open access: green
europepmc.org
Licence: academic.oup.com/pages/standard-publication-reuse-rights (vor)
Locations: American Journal of Respiratory and Critical Care Medicine (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Research Portal (Queen's University Belfast) (submittedVersion)
Funders: Public Health Agency (STL/3713/07, CDV/3650/07)
National Heart, Lung, and Blood Institute (R01HL092964, HL092964)
Topics: Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cystic Fibrosis Research Advances
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bacterial biofilms and quorum sensing
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Keywords: bronchiectasis, lung microbiome, bacterial abundance, exacerbations, sputum microbiome, Pseudomonas aeruginosa, Haemophilus influenzae, Prevotella, Veillonella, anaerobic bacteria, bacterial community composition, antibiotic therapy
MeSH terms: Aged, Anti-Bacterial Agents, Bronchiectasis, Cross-Sectional Studies, Female, Humans, Longitudinal Studies, Lung, Male, Sputum, Cohort Studies, Metagenome

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Lung Microbiota and Bacterial Abundance in Patients with Bronchiectasis when Clinically Stable and during Exacerbation

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks