Boucher, Richard C.

SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract

Hou, Y. J., Okuda, K., Edwards, C. E., Martinez, D. R., Asakura, T., Dinnon, K. H., Kato, T., Lee, R. E., Yount, B. L., Mascenik, T. M., et al. (2020) · Cell

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

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Mucus clearance as a primary innate defense mechanism for mammalian airways

Knowles, M. R., & Boucher, R. C. (2002) · Journal of Clinical Investigation

Cystic Fibrosis Research AdvancesAsthma and respiratory diseases

Cited by 1,054

Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients

Worlitzsch, D., Tarran, R., Ulrich, M., Schwab, U., Cekici, A., Meyer, K. C., Birrer, P., Bellon, G., Berger, J., Weiss, T., et al. (2002) · Journal of Clinical Investigation

Cystic Fibrosis Research AdvancesBacterial biofilms and quorum sensing

Cited by 932

SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo

Hou, Y. J., Chiba, S., Halfmann, P., Ehre, C., Kuroda, M., Dinnon, K. H., Leist, S. R., Schäfer, A., Nakajima, N., Takahashi, K., et al. (2020) · Science

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

Cited by 900

Muc5b is required for airway defence

Roy, M. G., Livraghi-Butrico, A., Fletcher, A. A., McElwee, M. M., Evans, S. E., Boerner, R. M., Alexander, S. N., Bellinghausen, L. K., Song, A. S., Petrova, Y. M., et al. (2014) · Nature

Glycosylation and Glycoproteins ResearchAsthma and respiratory diseases

Cited by 764

A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice

Leist, S. R., Dinnon, K. H., Schäfer, A., Tse, L. V., Okuda, K., Hou, Y. J., West, A., Edwards, C. E., Sanders, W., Fritch, E. J., et al. (2020) · Cell

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

Cited by 613

A Novel Mutation in the Cystic Fibrosis Gene in Patients with Pulmonary Disease but Normal Sweat Chloride Concentrations

Highsmith, W. E., Burch, L. H., Zhou, Z., Olsen, J. C., Boat, T. E., Spock, A., Gorvoy, J. D., Quittell, L., Friedman, K. J., Silverman, L. M., et al. (1994) · New England Journal of Medicine

Cystic Fibrosis Research AdvancesGenetic and Kidney Cyst Diseases

Cited by 441

Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction

Katsura, H., Sontake, V., Tata, A., Kobayashi, Y., Edwards, C. E., Heaton, B. E., Konkimalla, A., Asakura, T., Mikami, Y., Fritch, E. J., et al. (2020) · Cell Stem Cell

SARS-CoV-2 and COVID-19 Researchinterferon and immune responses

Cited by 416

Pulmonary epithelial sodium-channel dysfunction and excess airway liquid in pseudohypoaldosteronism

Kerem, E., Bistritzer, T., Hanukoglu, A., Hofmann, T., Zhou, Z., Bennett, W., MacLaughlin, E., Barker, P., Nash, M., Quittell, L., et al. (1999) · New England Journal of Medicine

Ion Transport and Channel RegulationCystic Fibrosis Research Advances

Cited by 356

Effective mucus clearance is essential for respiratory health

Randell, S. H., & Boucher, R. C. (2006) · American Journal of Respiratory Cell and Molecular Biology

Cystic Fibrosis Research AdvancesIon Transport and Channel Regulation

Cited by 335

Potentiator ivacaftor abrogates pharmacological correction of ΔF508 CFTR in cystic fibrosis

Cholon, D. M., Quinney, N. L., Fulcher, M. L., Esther, C. R., Das, J., Dokholyan, N. V., Randell, S. H., Boucher, R. C., & Gentzsch, M. (2014) · Science Translational Medicine

Cystic Fibrosis Research AdvancesInhalation and Respiratory Drug Delivery

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Lung microbiota and bacterial abundance in patients with bronchiectasis when clinically stable and during exacerbation

Tunney, M. M., Einarsson, G. G., Wei, L., Drain, M., Klem, E. R., Cardwell, C., Ennis, M., Boucher, R. C., Wolfgang, M. C., & Elborn, J. S. (2013) · American Journal of Respiratory and Critical Care Medicine

Cystic Fibrosis Research AdvancesBacterial biofilms and quorum sensing

Cited by 316

Conditionally reprogrammed cells represent a stem-like state of adult epithelial cells

Suprynowicz, F. A., Upadhyay, G., Krawczyk, E., Kramer, S. C., Hebert, J. D., Liu, X., Yuan, H., Cheluvaraju, C., Clapp, P. W., Boucher, R. C., et al. (2012) · Proceedings of the National Academy of Sciences

Pluripotent Stem Cells ResearchCancer Cells and Metastasis

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