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Cited by 286

The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.

Short-Term Exposure to Ambient Air Pollution and Asthma Mortality

Liu, Yuewei, Pan, Jingju, Zhang, Hai, Shi, Chunxiang, Li, Guo, Peng, Zhe, Ma, Jixuan, Zhou, Yun, Zhang, Lan·2019·American Journal of Respiratory and Critical Care Medicine

Abstract

Abstract Rationale Short-term exposure to air pollution has been associated with asthma exacerbation and increased healthcare use caused by asthma, but its effect on asthma mortality remains largely unknown. Objectives To quantitatively assess the association between short-term exposure to air pollution and asthma mortality. Methods We investigated 4,454 individuals who lived in Hubei province, China, and died from asthma between 2013 and 2018. A case-crossover design and conditional logistic regression models were applied for data analyses. Exposures to particulate matter ≤2.5 μm in aerodynamic diameter (PM2.5), particulate matter ≤10 μm in aerodynamic diameter (PM10), sulfur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), and ozone (O3) were estimated by inverse distance weighted averages of all monitoring stations within 50 km from each case’s home address. Measurements and Main Results Each interquartile range (IQR) increase of PM2.5 (lag 3; IQR, 47.1 μg/m3), NO2 (lag 03; IQR, 26.3 μg/m3), and O3 (lag 3; IQR, 52.9 μg/m3) were positively associated with asthma mortality, with odds ratios of 1.07 (95% confidence interval, 1.01–1.12), 1.11 (95% confidence interval, 1.01–1.22), and 1.09 (95% confidence interval, 1.01–1.18), respectively. There was no evidence of departure from linearity for these associations. Further adjustment for other pollutants did not change the associations materially. We did not observe significant associations between PM10, SO2, and CO exposures and asthma mortality. Overall, the estimates remained consistent in various sensitivity analyses. Conclusions Our results provide new evidence that short-term exposures to PM2.5, NO2, and O3 may increase asthma mortality risk. Further studies are needed to confirm our findings in other populations.

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Metadata

Authors
Liu, Y., Pan, J., Zhang, H., Shi, C., Li, G., Peng, Z., Ma, J., Zhou, Y., & Zhang, L.
Venue
American Journal of Respiratory and Critical Care Medicine
Published
2019-07-01
Volume
200
Issue
1
Pages
24-32
ISSN
  • 1073-449X (ISSN-L)
  • 1535-4970
OpenAlex
W2921695473
Cited by
286
References
48
FWCI
13.58
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Short-Term Exposure to Ambient Air Pollution and Asthma Mortality. https://app.cochat.ai/papers/10.1164/rccm.201810-1823oc
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Liu, Y., Pan, J., Zhang, H., Shi, C., Li, G., Peng, Z., Ma, J., Zhou, Y., & Zhang, L. (2019). Short-Term Exposure to Ambient Air Pollution and Asthma Mortality. American Journal of Respiratory and Critical Care Medicine. https://doi.org/10.1164/rccm.201810-1823oc

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