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Cited by 249

The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.

Initiating Pharmacologic Treatment in Tobacco-Dependent Adults. An Official American Thoracic Society Clinical Practice Guideline

Open access
Leone, Frank T., Zhang, Yuqing, Evers-Casey, Sarah, Evins, A. Eden, Eakin, Michelle N., Fathi, Joelle, Fennig, Kathleen, Folan, Patricia, Galiatsatos, Panagis, Gogineni, Hyma, Kantrow, Stephen, Kathuria, Hasmeena, Lamphere, Thomas, Neptune, Enid, Pacheco, Manuel C., Pakhale, Smita, Prezant, David, Sachs, David P. L., Toll, Benjamin, Upson, Dona, Xiao, Dan, Cruz-Lopes, Luciane, Fulone, Izabela, Murray, Rachael L., O’Brien, Kelly K., Pavalagantharajah, Sureka, Ross, Stephanie, Zhang, Yuan, Zhu, Meng, Farber, Harold J.·2020·American Journal of Respiratory and Critical Care Medicine

Abstract

Abstract Background Current tobacco treatment guidelines have established the efficacy of available interventions, but they do not provide detailed guidance for common implementation questions frequently faced in the clinic. An evidence-based guideline was created that addresses several pharmacotherapy-initiation questions that routinely confront treatment teams. Methods Individuals with diverse expertise related to smoking cessation were empaneled to prioritize questions and outcomes important to clinicians. An evidence-synthesis team conducted systematic reviews, which informed recommendations to answer the questions. The GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) approach was used to rate the certainty in the estimated effects and the strength of recommendations. Results The guideline panel formulated five strong recommendations and two conditional recommendations regarding pharmacotherapy choices. Strong recommendations include using varenicline rather than a nicotine patch, using varenicline rather than bupropion, using varenicline rather than a nicotine patch in adults with a comorbid psychiatric condition, initiating varenicline in adults even if they are unready to quit, and using controller therapy for an extended treatment duration greater than 12 weeks. Conditional recommendations include combining a nicotine patch with varenicline rather than using varenicline alone and using varenicline rather than electronic cigarettes. Conclusions Seven recommendations are provided, which represent simple practice changes that are likely to increase the effectiveness of tobacco-dependence pharmacotherapy.

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Metadata

Authors
Leone, F. T., Zhang, Y., Evers-Casey, S., Evins, A. E., Eakin, M. N., Fathi, J., Fennig, K., Folan, P., Galiatsatos, P., Gogineni, H., Kantrow, S., Kathuria, H., Lamphere, T., Neptune, E., Pacheco, M. C., Pakhale, S., Prezant, D., Sachs, D. P. L., Toll, B., Upson, D., Xiao, D., Cruz-Lopes, L., Fulone, I., Murray, R. L., O’Brien, K. K., Pavalagantharajah, S., Ross, S., Zhang, Y., Zhu, M., & Farber, H. J.
Venue
American Journal of Respiratory and Critical Care Medicine
Published
2020-07-15
Volume
202
Issue
2
Pages
e5-e31
ISSN
  • 1073-449X (ISSN-L)
  • 1535-4970
OpenAlex
W3043122900
Cited by
249
References
28
FWCI
20.37
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Initiating Pharmacologic Treatment in Tobacco-Dependent Adults. An Official American Thoracic Society Clinical Practice Guideline. https://app.cochat.ai/papers/10.1164/rccm.202005-1982st
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Leone, F. T., Zhang, Y., Evers-Casey, S., Evins, A. E., Eakin, M. N., Fathi, J., Fennig, K., Folan, P., Galiatsatos, P., Gogineni, H., Kantrow, S., Kathuria, H., Lamphere, T., Neptune, E., Pacheco, M. C., Pakhale, S., Prezant, D., Sachs, D. P. L., Toll, B., . . . Farber, H. J. (2020). Initiating Pharmacologic Treatment in Tobacco-Dependent Adults. An Official American Thoracic Society Clinical Practice Guideline. American Journal of Respiratory and Critical Care Medicine. https://doi.org/10.1164/rccm.202005-1982st

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.