The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Ocular Rigidity in Living Human Eyes
Abstract
PURPOSE: To measure the rigidity coefficient of a large number of subjects at clinically encountered intraocular pressures (IOPs) and to examine the possible correlation of ocular rigidity with other factors, such as the age of the patients, ocular parameters (axial length and corneal thickness), and pathologic conditions affecting the eye. METHODS: The pressure-volume relationship and the ocular rigidity coefficient (K) were determined in 79 eyes undergoing cataract surgery, by injecting 200 microL of saline solution (in steps of 4.5 microL) through the limbus into the anterior chamber, while continually monitoring the IOP with a transducer, up to the limit of 60 mm Hg. Data within an IOP range of 10 to 35 mm Hg were used to calculate the scleral rigidity coefficient. All measurements were taken at the same time of day, to eliminate any possible diurnal variation. RESULTS: The mean ocular rigidity coefficient was 0.0126 mm Hg/microL (95% confidence interval [CI], 0.0112-0.0149). A statistically significant positive correlation between the rigidity coefficient and age of the patient was found (P = 0.02), whereas similar findings were not observed for the examined ocular parameters (axial length, P = 0.09; and corneal thickness, P = 0.12). No correlation was found for patients with diabetes mellitus (P = 0.39), age-related macular degeneration (P = 0.55), and hypertension (P = 0.45). CONCLUSIONS: The present study provides quantitative data on the ocular rigidity coefficient based on measurements in a large series of living human eyes. A positive correlation between the ocular rigidity coefficient and the patient's age was documented.
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Cites
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Self-citationDetermination of the True Intraocular Pressure and Modulus of Elasticity of the Human Cornea in vivo
Orssengo, G. (1999) · Bulletin of Mathematical Biology · doi:10.1006/bulm.1999.0102 · Cited by 304
Bhan, A., Browning, A. C., Shah, S., HAMILTON, R. D., Dave, D., & Dua, H. S. (2002) · PubMed · Cited by 254
The role of the atherosclerotic process in the pathogenesis of age-related macular degeneration
Friedman, E. (2000) · American Journal of Ophthalmology · doi:10.1016/s0002-9394(00)00643-7 · Cited by 220
Pressure-volume relation for the living human eye
Silver, D. M., & Geyer, O. (2000) · Current Eye Research · doi:10.1076/0271-3683(200002)2021-dft115 · Cited by 148
Increased Scleral Rigidity and Age-related Macular Degeneration
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Cited by
Pepose, J. S., Feigenbaum, S. K., Qazi, M. A., Sanderson, J. P., & Roberts, C. J. (2007) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2006.09.036 · Cited by 369
Wireless contact lens sensor for intraocular pressure monitoring: assessment on enucleated pig eyes
Leonardi, M., Pitchon, E. M., Bertsch, A., Renaud, P., & Mermoud, A. (2009) · Acta Ophthalmologica · doi:10.1111/j.1755-3768.2008.01404.x · Cited by 300
Chen, P.-J., Saati, S., Varma, R., Humayun, M. S., & Tai, Y.-C. (2010) · Journal of Microelectromechanical Systems · doi:10.1109/jmems.2010.2049825 · Cited by 264
Metadata
- Authors
- Pallikaris, I. G., Kymionis, G. D., Ginis, H. S., Kounis, G. A., & Tsilimbaris, M. K.
- Venue
- Investigative Opthalmology & Visual Science
- Published
- 2005-02-01
- Volume
- 46
- Issue
- 2
- Pages
- 409
- ISSN
- 0146-0404 (ISSN-L)
- 1552-5783
- OpenAlex
- W2047028621
- Cited by
- 301
- References
- 9
- FWCI
- 14.55
- Type
- journal article
- Language
- en
- Open access
- closed
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