Cited by 184Estrogen and related hormone effectsSteroid Chemistry and BiochemistryPharmacogenetics and Drug Metabolism

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Studies on Phenolic Steroids in Human Subjects. II. The Metabolic Fate and Hepato-Biliary-Enteric Circulation of C14-Estrone and C14-Estradiol in Women1

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Sandberg, Avery A., Slaunwhite, W. Roy·1957·Journal of Clinical Investigation

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METHODS AND MATERIALSOne to two /sc. of 16-C1'-estrone (B1) or 16-CM-estra- diol-17,B (E2) 2 (both 1Elc.per 370 pg.) were injected 2C4.-estrone and C"-estradiol were purchased from Charles E. Frosst & Co., Montreal, Canada.When the preparations were chromatographed in our laboratory, 1266

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THE PHYSIOLOGICAL DISPOSITION AND METABOLIC FATE OF HYDROCORTISONE IN MAN
Peterson, R. E., Wyngaarden, J. Β., Guerra, S., Brodie, B. B., & Bunim, J. J. (1955) · Journal of Clinical Investigation · doi:10.1172/jci103233 · Cited by 372
THE PHYSIOLOGICAL DISPOSITION AND METABOLIC FATE OF HYDROCORTISONE IN MAN
Peterson, R. E., & Wyngaarden, J. Β. (1955) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1955.tb42479.x · Cited by 94
THE FATE OF HYDROCORTISONE-4-C14 IN MAN 1
HELLMAN, L., Bradlow, H. L., Adesman, J., Fukushima, D. K., Kulp, J. L., & Gallagher, T. F. (1954) · Journal of Clinical Investigation · doi:10.1172/jci102984 · Cited by 92
METABOLISM OF 4-C14-TESTOSTERONE IN HUMAN SUBJECTS. I. DISTRIBUTION IN BILE, BLOOD, FECES AND URINE
Sandberg, A. A., & Slaunwhite, W. R. (1956) · Journal of Clinical Investigation · doi:10.1172/jci103389 · Cited by 90
METABOLISM OF 4-C14-CORTISOL IN MAN: BODY DISTRIBUTION AND RATES OF CONJUGATION*†
Migeon, C. J., Sandberg, A. A., DECKER, H. A., SMITH, D. F., PAUL, A. C., & SAMUEL, L. T. (1956) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-16-9-1137b · Cited by 88
The isolation of 16-epioestriol from the urine of pregnant women
Marrian, G. F., & Bauld, W. S. (1955) · Biochemical Journal · doi:10.1042/bj0590136 · Cited by 77
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Beer, C. T., & Gallagher, T. F. (1955) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)70972-1 · Cited by 73
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Smith, G. V. S., & Smith, O. W. (1938) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(38)90572-1 · Cited by 70
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Slaunwhite, W. R., & Sandberg, A. A. (1956) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(56)90065-0 · Cited by 63
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Fukushima, D. K., Bradlow, H. L., Dobriner, K., & Gallagher, T. F. (1954) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)50857-2 · Cited by 55

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Authors: Sandberg, A. A., & Slaunwhite, W. R.
Affiliations: Roswell Park Comprehensive Cancer Center (US)
Venue: Journal of Clinical Investigation
Publisher: American Society for Clinical Investigation
Published: 1957-08-01
Volume: 36
Issue: 8
Pages: 1266-1278
ISSN: 0021-9738 (ISSN-L)
DOI: 10.1172/jci103524
PMC: PMC1072719
OpenAlex: W2145281171
Cited by: 184
References: 41
Citations by year: 2026: 6 · 2025: 4 · 2024: 4 · 2023: 6 · 2022: 1 · 2021: 1 · 2020: 1 · 2019: 5 · 2018: 1 · 2016: 1 · 2014: 1 · 2013: 1
FWCI: 5.64
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Journal of Clinical Investigation (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Estrogen and related hormone effects
Physical Sciences › Chemistry › Organic Chemistry › Steroid Chemistry and Biochemistry
Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmacogenetics and Drug Metabolism
Keywords: phenolic steroids, estrone, estradiol, radiolabeled steroids, metabolic fate, hepatic metabolism, biliary excretion, intestinal circulation, women, steroid metabolism
MeSH terms: Estradiol, Estrogens, Estrone, Female, Humans, Steroids, Gastrointestinal Tract, Lipid Metabolism

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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

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Studies on Phenolic Steroids in Human Subjects. II. The Metabolic Fate and Hepato-Biliary-Enteric Circulation of C14-Estrone and C14-Estradiol in Women1

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