Cited by 339Lipid metabolism and disordersCholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

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Mechanism of plasma cholesteryl ester transfer in hypertriglyceridemia.

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Mann, C J, Yen, F T, Grant, A M, Bihain, B E·1991·Journal of Clinical Investigation

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Abstract

Plasma net cholesteryl ester (CE) transfer and optimum cho- lesteryl ester transfer protein (CETP) activity were determined in primary hypertriglyceridemic (a = 11) and normolipidemic (a = 15) individuals.The hypertriglyceridemic group demon- strated threefold greater net CE transfer leading to enhanced accumulation of CE in VLDL.This increased net transfer was not accompanied by a change in CETP activity.In normolipide- mia, but not in hypertriglyceridemia, net CE transfer correlated with VLDL triglyceride (r = 0.92, P < 0.001).In contrast, net CE transfer in hypertriglyceridemia, but not in normolipide- mia, correlated with CETP activity (r = 0.73, P < 0.01).Correc- tion of hypertriglyceridemia with bezafibrate reduced net CE transfer towards normal and restored the correlation with VLDL triglyceride (r = 0.90, P < 0.005) while suppressing the correlation with CETP activity.That net CE transfer depends on VLDL concentration was confirmed by an increase ofnet CE transfer in normolipidemic plasma supplemented with purified VLDL.Supplementation of purified CETP to normolipidemic plasma did not stimulate net CE transfer.In contrast, net CE transfer was enhanced by addition of CETP to both plasma supplemented with VLDL and hypertriglyceridemic plasma.Thus, in normal subjects, VLDL concentration determines the rate of net CE transfer.CETP becomes rate limiting as VLDL concentration increases, i.e, in hypertriglyceridemia. (J.Clin.Invest.1991.88:2059-2066.)Key words: cholesteryl ester transfer protein * very low density lipoprotein -high density lipoprotein -cardiovascular disease * reverse cholesterol trans- port MO.Bezafibrate (2-[4-[2-[(4-chlorobenzoyl)amino]-ethyl]phenoxy]-2methylpropanoic acid) was obtained from Boehringer Mannheim (for- merly MCP Pharmaceuticals), Livingstone, Scotland. Cholesteryl Ester Transfer in Hypertriglyceridemia 2059

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PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
Lowry, O. H., Rosebrough, N., Farr, A. L., & Randall, R. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52451-6 · Cited by 316,394
Incidence of Coronary Heart Disease and Lipoprotein Cholesterol Levels
Castelli, W. P. (1986) · JAMA · doi:10.1001/jama.256.20.2835 · Cited by 2,512
HDL cholesterol and other lipids in coronary heart disease. The cooperative lipoprotein phenotyping study
Castelli, W. P., Doyle, J. T., Gordon, T., Hames, C. G., Hjortland, M. C., Hulley, S. B., Kagan, A., & Zukel, W. J. (1977) · Circulation · doi:10.1161/01.cir.55.5.767 · Cited by 1,492
Increased High-Density Lipoprotein Levels Caused by a Common Cholesteryl-Ester Transfer Protein Gene Mutation
Inazu, A., Brown, M. L., Hesler, C. B., Agellon, L. B., Koizumi, J., Takata, K., Maruhama, Y., Mabuchi, H., & Tall, A. R. (1990) · New England Journal of Medicine · doi:10.1056/nejm199011013231803 · Cited by 862
Separation and quantitation of subclasses of human plasma high density lipoproteins by a simple precipitation procedure
Gidez, L. I., Miller, G. J., Burstein, M., Slagle, S., & Eder, H. (1982) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)38059-7 · Cited by 757
PLASMA LIPID TRANSFER PROTEINS
Tall, A. R. (1995) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.64.070195.001315 · Cited by 639
Molecular basis of lipid transfer protein deficiency in a family with increased high-density lipoproteins
Brown, M. L., Inazu, A., Hesler, C. B., Agellon, L. B., Mann, C., Whitlock, M. E., Marcel, Y. L., Milne, R. W., Koizumi, J., Mabuchi, H., et al. (1989) · Nature · doi:10.1038/342448a0 · Cited by 470
Self-citation
Plasma lipid transfer proteins.
Tall, A. R. (1988) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)38819-2 · Cited by 377
Reduced high density lipoprotein cholesterol in human cholesteryl ester transfer protein transgenic mice
Agellon, L. B., Walsh, A., Hayek, T., Moulin, P., Jiang, X., Shelanski, S. A., Breslow, J. L., & Tall, A. R. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)99088-5 · Cited by 297
High-density lipoprotein cholesterol and coronary heart disease in hypercholesterolemic men: the Lipid Research Clinics Coronary Primary Prevention Trial.
Gordon, D. J., Knoke, J. D., Probstfield, J. L., Superko, H. R., & Tyroler, H. A. (1986) · Circulation · doi:10.1161/01.cir.74.6.1217 · Cited by 289

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Importance of high-density lipoprotein cholesterol and triglyceride levels in coronary heart disease
Sprecher, D. L., Watkins, T. R., Behar, S., Brown, W. V., Bloomfield, H. E., & Schaefer, E. J. (2003) · The American Journal of Cardiology · doi:10.1016/s0002-9149(02)03309-x · Cited by 23
Role of Endothelial Lipase in Plasma HDL levels in a Murine Model of Hypertriglyceridemia
Tanaka, H., Ishida, T., Johnston, T. P., Yasuda, T., Ueyama, T., Kojima, Y., Kundu, R. K., Quertermous, T., Ishikawa, Y., & Hirata, K. (2009) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.no844 · Cited by 23
Differential impact of plasma triglycerides on HDL-cholesterol and HDL-apo A-I in a large cohort
Tremblay, A. J., Sniderman, A. D., Gagné, C., Bergeron, J., & Couture, P. (2006) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2006.06.014 · Cited by 23
Control of cholesteryl ester transfer protein activity by sequestration of lipid transfer inhibitor protein in an inactive complex
He, Y., Greene, D. J., Kinter, M. T., & Morton, R. E. (2008) · Journal of Lipid Research · doi:10.1194/jlr.m800087-jlr200 · Cited by 23
Neutral lipid mass transfer among lipoproteins in plasma from normolipidemic subjects is not an equimolar heteroexchange.
Liu, X. Q., & Bagdade, J. D. (1995) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)41093-4 · Cited by 23
Differences in HDL-cholesterol:apoA-I + apoA-II ratio and apoE phenotype with albuminuric status in Type I diabetic patients
Soedamah‐Muthu, S. S., Colhoun, H. M., Taskinen, M., Idzior−Waluś, B., & Fuller, J. (2000) · Diabetologia · doi:10.1007/s001250051538 · Cited by 23
The atherogenic role of triglycerides and small, dense low density lipoproteins: impact of ciprofibrate therapy
Chapman, M. J., & Bruckert, É. (1996) · Atherosclerosis · doi:10.1016/0021-9150(96)05853-4 · Cited by 23
Cholesteryl ester transfer and cholesterol esterification in type 1 diabetes: relationships with plasma glucose
Chang, C., Tso, T. K., Snook, J., Huang, Y. S., Lozano, R. A., & Zipf, W. B. (2001) · Acta Diabetologica · doi:10.1007/s005920170027 · Cited by 22
“[41] may not apply to the type 1 diabetic children we investigated in the present report.”
BackgroundInfluential
Effect of treatment with simvastatin on serum cholestryl ester transfer in patients on dialysis
Walker, R. J., Sutherland, W. H. F., Walker, H., MacMahon, S. W., & Robson, R. A. (1997) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/12.1.87 · Cited by 22
Abnormal acyltransferase activities and accelerated cholesteryl ester transfer in patients with nephrotic syndrome
Subbaiah, P. V., & Rodby, R. A. (1994) · Metabolism · doi:10.1016/0026-0495(94)90055-8 · Cited by 22
Association between HDL-cholesterol and the Taq1B polymorphism in the cholesterol ester transfer protein gene in obese women
Heilbronn, L. K., Noakes, M., & Clifton, P. M. (2002) · Atherosclerosis · doi:10.1016/s0021-9150(01)00733-x · Cited by 22
Fenofibrate improves postprandial chylomicron clearance in II B hyperlipoproteinemia
F�ger, B., Drexel, H., Hopferwieser, T., Miesenb�ck, G., Ritsch, A., Lechleitner, M., Tr�binger, G., & Patsch, J. R. (1994) · Journal of Molecular Medicine · doi:10.1007/bf00180044 · Cited by 22
The surface cholesteryl ester content of donor and acceptor particles regulates CETP: a liposome-based approach to assess the substrate properties of lipoproteins
Morton, R. E., & Greene, D. J. (2003) · Journal of Lipid Research · doi:10.1194/jlr.m300063-jlr200 · Cited by 21
“limiting for net mass transfer (57, 58), other factors are”
Background
Ciprofibrate increases cholesteryl ester transfer protein gene expression and the indirect reverse cholesterol transport to the liver
Bighetti, E. J. B., Patrício, P. R., Casquero, A. C., Berti, J. A., & Oliveira, H. C. F. (2009) · Lipids in Health and Disease · doi:10.1186/1476-511x-8-50 · Cited by 21
“Regarding the plasma levels of CETP, varying results were obtained in fibrate treated hyperlipidemic subjects, as follow: CETP decreased with bezafibrate and fenofibrate [24-27], or did not change with gemfibrozil, fenofibrate and bezafibrate [25,28-31], or increased with gemfibrozil [32].”
Dietary, Physiological, and Genetic Impacts on Postprandial Lipid Metabolism
López‐Miranda, J., & Marı́n, C. (2009) · Frontiers in neuroscience · doi:10.1201/9781420067767-c17 · Cited by 21
Hypertriglyceridemia
Jonkers, I. J. A. M., Smelt, A. H. M., & van der Laarse, A. (2001) · American Journal of Cardiovascular Drugs · doi:10.2165/00129784-200101060-00005 · Cited by 21
Net mass transfer of plasma cholesteryl esters and lipid transfer proteins in normolipidemic patients with peripheral vascular disease
Rühling, K., Lang, A., Richard, F., van Tol, A., Eisele, B., Herzberg, V., & Till, U. (1999) · Metabolism · doi:10.1016/s0026-0495(99)90144-0 · Cited by 20
An interaction between the TaqIB polymorphism of cholesterol ester transfer protein and smoking is associated with changes in plasma high‐density lipoprotein cholesterol levels in Turks
Hodoğlugil, U., Williamson, D., Huang, Y., & Mahley, R. W. (2005) · Clinical Genetics · doi:10.1111/j.1399-0004.2005.00467.x · Cited by 20
“As CETP activity is not different in individuals with low and high triglycerides in this or other studies (52, 53), the interaction of plasma triglycerides and CETP polymorphism on HDL-C may be independent of CETP activity.”
Background
Apolipoprotein CI overexpression is not a relevant strategy to block cholesteryl ester transfer protein (CETP) activity in CETP transgenic mice
Gautier, T., Masson, D., JONG, M. C., de Barros, J.-P. P., Duverneuil, L., Guern, N. L., Deckert, V., Dumont, L., Bataille, A., Zak, Z., et al. (2004) · Biochemical Journal · doi:10.1042/bj20041149 · Cited by 22
The hypolipidemic action of bezafibrate therapy in hypertriglyceridemia is mediated by upregulation of lipoprotein lipase: no effects on VLDL substrate affinity to lipolysis or LDL receptor binding
de Man, F. H. A. F., de Beer, F., van der Laarse, A., Jansen, H., Leuven, J. A. G., Souverijn, J. H. M., Vroom, T. F. F. P., Schoormans, S. C. M., Fruchart, J., Havekes, L. M., et al. (2000) · Atherosclerosis · doi:10.1016/s0021-9150(00)00409-3 · Cited by 21
“Enrichment of VLDL by CEs in HTG has been described before and is explained by the fact that high VLDL concentrations passively induce an increased transfer of TG to the LDL and HDL fraction in exchange for CEs [33].”
Background
Increased large VLDL particles confer elevated cholesteryl ester transfer in diabetes
Dullaart, R. P. F., de Vries, R., Kwakernaak, A. J., Perton, F. G., & Dallinga‐Thie, G. M. (2014) · European Journal of Clinical Investigation · doi:10.1111/eci.12377 · Cited by 19
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Russo, G. T., Horvath, K. V., Benedetto, A. D., Giandalia, A., Cucinotta, D., & Asztalos, B. F. (2009) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2009.11.011 · Cited by 19
Decreased plasma cholesterol esterification and cholesteryl ester transfer in hypopituitary patients on glucocorticoid replacement therapy
Beentjes, J. A. M., van Tol, A., Sluiter, W. J., & Dullaart, R. P. F. (2000) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.1080/003655100750044839 · Cited by 19
Evidence for a cholesteryl ester donor activity of LDL particles during alimentary lipemia in normolipidemic subjects
Lassel, T. S., Guérin, M., Auboiron, S., Guy-grand, B., & Chapman, M. J. (1999) · Atherosclerosis · doi:10.1016/s0021-9150(99)00161-6 · Cited by 19
“The relative proportions of both donor and acceptor lipoprotein particles are known to significantly influence cholesteryl ester transfer mediated by CETP [15– 18].”
Background
Rates of cholesterol esterification and esterified cholesterol net mass transfer between high‐density lipoproteins and apolipoprotein B‐containing lipoproteins in Type 1 diabetes
Valabhji, J., Donovan, J., McColl, A. J., Schächter, M., Richmond, W., & Elkeles, R. S. (2002) · Diabetic Medicine · doi:10.1046/j.1464-5491.2002.00714.x · Cited by 19
Postprandial reverse cholesterol transport in type 2 diabetic patients: effect of a lipid lowering treatment
Autran, D., Attia, N., Dedecjus, M., Durlach, V., & Girard-Globa, A. (2000) · Atherosclerosis · doi:10.1016/s0021-9150(00)00428-7 · Cited by 19
“The transfer of TG to HDL by CETP in exchange for cholesteryl esters is strongly enhanced by the presence of high concentrations of TG-rich particles [28] such as occur during lipid absorption.”
Background
Lipoprotein composition influences cholesteryl ester transfer in alcohol abusers
Liinamaa, J., Kesdniemi, Y. A., & Savolainen, M. J. (1998) · Annals of Medicine · doi:10.3109/07853899809005861 · Cited by 19
Plasma cholesteryl ester transfer activity is modulated by the phase transition of the lipoprotein core
Morton, R. E., & Parks, J. S. (1996) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37556-8 · Cited by 19
Fasting plasma triacylglycerol concentrations predict adverse changes in lipoprotein metabolism after a normal meal
Potts, J. L., Humphreys, S. M., Coppack, S. W., Fisher, R. M., Gibbons, G. F., & Fray, K. N. (1994) · British Journal Of Nutrition · doi:10.1079/bjn19940013 · Cited by 18
“Within relatively normal ranges of plasma lipid concentrations, this process is governed by the lipid concentrations in the various lipoprotein fractions rather than by the activity of CETP in individual subjects (Mann et al. 1991).”
Background
Alterations of Lipoprotein Fluidity by Non‐Esterified Fatty Acids Known to Affect Cholesteryl Ester Transfer Protein Activity
Foucher, C., Lagrost, L., Maupoil, V., Meste, M. L., Rochette, L., & Gambert, P. (1996) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1996.00436.x · Cited by 18
Cholesteryl ester transfer protein: gathering momentum as a genetic marker and as drug target
Ritsch, A., & Patsch, J. R. (2003) · Current Opinion in Lipidology · doi:10.1097/00041433-200304000-00009 · Cited by 18
Cholesteryl ester transfer protein inhibition by PD 140195
Bisgaier, C. L., Essenburg, A. D., Minton, L. L., Homan, R., Blankley, C. J., & White, A. D. (1994) · Lipids · doi:10.1007/bf02536247 · Cited by 18
The role of CETP inhibition in dyslipidemia
Harchaoui, K. E., van der Steeg, W. A., Stroes, E. S. G., & Kastelein, J. J. P. (2007) · Current Atherosclerosis Reports · doi:10.1007/s11883-007-0008-5 · Cited by 18
HDL in risk prediction and its direct and indirect involvement in atherogenesis
Durrington, P. N. (2002) · Atherosclerosis Supplements · doi:10.1016/s1567-5688(02)00042-9 · Cited by 17
Plasma Cholesterol Esterification And Transfer, the Menopause, And Hormone Replacement Therapy in Women1
Lewis-Barned, N. J., Sutherland, W. H. F., Walker, R. J., Walker, H. L., de Jong, S. A., Edwards, E. A., & Markham, V. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.10.6022 · Cited by 17
“However, levels of CETP are not ratelimiting for cholesteryl ester transfer in normotriglyceridemic subjects ( 12 ).”
Background
Increased production rates of LDL are common in individuals with low plasma levels of HDL cholesterol, independent of plasma triglyceride concentrations.
Ginsberg, H. N., Ngai, C. I., Wang, X. J., & Ramakrishnan, R. (1993) · Arteriosclerosis and Thrombosis A Journal of Vascular Biology · doi:10.1161/01.atv.13.6.842 · Cited by 17
Lipid Transfer Inhibitor Protein Activity Deficiency in Normolipidemic Uremic Patients on Continuous Ambulatory Peritoneal Dialysis
Serdyuk, A. P., & Morton, R. E. (1997) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.17.9.1716 · Cited by 17
Cholesteryl ester transfer protein and lecithin: Cholesterol acyltransferase activities in hispanic and anglo postmenopausal women: Associations with total and regional body fat
Greaves, K. A., Going, S. B., Fernández, M. L., Milliken, L. A., Lohman, T. G., Bassford, T. L., & McNamara, D. J. (2003) · Metabolism · doi:10.1053/meta.2003.50045 · Cited by 16
Accelerated cholesteryl ester transfer and altered lipoprotein composition in diabetic cynomolgus monkeys.
Bagdade, J. D., Wagner, J. D., Rudel, L. L., & Clarkson, T. B. (1995) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)40061-6 · Cited by 16
Marine lipids normalize cholesteryl ester transfer in IDDM
Bagdade, J. D., Ritter, M. C., & Subbaiah, P. V. (1996) · Diabetologia · doi:10.1007/bf00400682 · Cited by 16
“Mann et al. [ 24 ] have also shown that VLDL mass is an important positive regulator of CET [24].”
BackgroundInfluential
Interrelationships between postprandial lipoprotein B:CIII particle changes and high-density lipoprotein subpopulation profiles in mixed hyperlipoproteinemia
Saïdi, Y., Sich, D., Camproux, A., Egloff, M., Federspiel, M.-C., Gautier, V., Raisonnier, A., Turpin, G., & Beucler, I. (1999) · Metabolism · doi:10.1016/s0026-0495(99)90011-2 · Cited by 16
Plasma cholesteryl ester transfer protein is lowered by treatment of hypercholesterolemia with cholestyramine*
Carrilho, A. J. F., Medina, W. L., Nakandakare, E. R., & Quintão, E. C. R. (1997) · Clinical Pharmacology & Therapeutics · doi:10.1016/s0009-9236(97)90154-5 · Cited by 16
Plasma Cholesteryl Ester Transfer, But Not Cholesterol Esterification, Is Related to Lipoprotein-Associated Phospholipase A2: Possible Contribution to an Atherogenic Lipoprotein Profile
Dullaart, R. P. F., Constantinides, A., Perton, F. G., van Leeuwen, J. J. J., van Pelt, L. J., de Vries, R., & van Tol, A. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-2139 · Cited by 15
The lipid substrate preference of CETP controls the biochemical properties of HDL in fat/cholesterol-fed hamsters
Morton, R. E., Mihna, D., & Liu, Y. (2021) · Journal of Lipid Research · doi:10.1016/j.jlr.2021.100027 · Cited by 15
“Low VLDL constrains plasma CETP activity in vivo by limiting the availability of TG for the CETPmediated heteroexchange of CE and TG (7, 8).”
Background
Phage-displayed recombinant single-chain antibody fragments with high affinity for cholesteryl ester transfer protein (CETP): cDNA cloning, characterization and CETP quantification
Ritsch, A., Ebenbichler, C. F., Naschberger, E., Schgoer, W., Stanzl, U., Dietrich, H., Heinrich, P. C., Saito, K., & Patsch, J. R. (2004) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm.2004.046 · Cited by 15
“were able to show that an increase in CE transfer by addition of CETP depends on the concentration of TG-rich lipoproteins (8).”
Background
An elevation of triglycerides reflecting decreased triglyceride clearance may not be pathogenic – relevance to high-carbohydrate diets
McCarty, M. F. (2004) · Medical Hypotheses · doi:10.1016/j.mehy.2002.11.002 · Cited by 15
“However, what about the impact of elevated triglycerides on the size of LDL and HDL particles? Transfer of cholesterol esters from these lipoproteins to VLDL or chylomicrons, catalyzed by cholesterol ester transfer protein (CETP), reduces the size of LDL and HDL, and this effect is more prominent when triglyceride lev…”
Background
Partial suppression of CETP activity beneficially modifies the lipid transfer profile of plasma
Morton, R. E., & Greene, D. J. (2006) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2006.06.030 · Cited by 15
Cholesteryl Ester Transfer Protein and Atherogenesis
Tall, A. R., SHARP, D., Zhong, S., Hayek, T., Masucci-Magoulas, L., Rubin, E. M., & Breslow, J. L. (1997) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1997.tb52000.x · Cited by 15
Effects of Diacylglycerol Oil on Adiposity in Obese Children: Initial Communication
Matsuyama, T., Shoji, K., Watanabe, H., Shimizu, M., Saotome, Y., Nagao, T., Matsuo, N., Hase, T., Tokimitsu, I., & Nakaya, N. (2006) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem.2006.19.6.795 · Cited by 15
Dynamics of lipoprotein transport in the human circulatory system
Fielding, P. E., & Fielding, C. J. (1996) · New comprehensive biochemistry · doi:10.1016/s0167-7306(08)60525-6 · Cited by 14
Fluvastatin reduces levels of plasma apo B-containing particles and increases those of LpA-I
Dallongeville, J., Fruchart, J., Bard, J., & Pfrister, P. (1994) · The American Journal of Medicine · doi:10.1016/0002-9343(94)90229-1 · Cited by 14
Markedly Elevated Lipid Transfer Inhibitor Protein in Hypercholesterolemic Subjects Is Mitigated by Plasma Triglyceride Levels
Morton, R. E., Nunes, V. S., Izem, L., & Quintão, E. C. R. (2001) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/hq1001.096722 · Cited by 14
Factors Explaining Mothers' Breastfeeding Satisfaction
Kim, S. H. (2009) · Korean journal of women health nursing/Yeoseong geon'gang ganho hag'hoeji/Yeoseong geon-gang ganho hakoeji · doi:10.4069/kjwhn.2009.15.4.270 · Cited by 13
CETP and oxidized LDL levels increase in dyslipidemic subjects
Wang, J., Gu, Q., Li, K., & Zhang, C. (2007) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2007.05.010 · Cited by 13
Lecithin:Cholesterol Acyltransferase Activity and Cholesteryl Ester Transfer Rate in Patients with Diabetes Mellitus
Dirican, M. (2003) · DergiPark (Istanbul University) · Cited by 13
Conversion of lipid transfer inhibitor protein (apolipoprotein F) to its active form depends on LDL composition
Morton, R. E., & Greene, D. J. (2011) · Journal of Lipid Research · doi:10.1194/jlr.m018283 · Cited by 12
Effect of cholesteryl ester transfer protein (CETP) expression on diet-induced hyperlipidemias in transgenic rats
Zak, Z., Gautier, T., Dumont, L., Masson, D., Deckert, V., Duverneuil, L., de Barros, J.-P. P., Guern, N. L., Schneider, M., Moulin, P., et al. (2004) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2004.10.006 · Cited by 12
Phospholipid and cholesteryl ester transfer are increased in lipoprotein lipase deficiency
Kaser, S., Sandhofer, A., Hölzl, B., Gander, R., Ebenbichler, C. F., Paulweber, B., & Patsch, J. R. (2003) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.2003.01091.x · Cited by 12
Characterization of LDL Particle Size Among Carriers of a Defective or a Null Mutation in the Lipoprotein Lipase Gene
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Short-term response to dietary counseling of hyperlipidemic outpatients of a lipid clinic
Dallongeville, J., LeBoeuf, N. R., Blais, C., Touchette, J., Gervais, N., & Davignon, J. (1994) · Journal of the American Dietetic Association · doi:10.1016/0002-8223(94)90156-2 · Cited by 12
A Randomized, Placebo‐Controlled Trial to Assess the Effects of 8 Weeks of Administration of GSK256073, a Selective GPR109A Agonist, on High‐Density Lipoprotein Cholesterol in Subjects With Dyslipidemia
Olson, E. J., Mahar, K. M., Haws, T. F., Fossler, M. J., Gao, F., de Gouville, A., Sprecher, D. L., & Lepore, J. J. (2019) · Clinical Pharmacology in Drug Development · doi:10.1002/cpdd.704 · Cited by 11
Reduced Reverse Cholesterol Transport Efficacy in Healthy Men with Undesirable Postprandial Triglyceride Response
Motte, A., Gall, J., Salem, J., Dasque, E., Lebot, M., Frisdal, É., Galier, S., Villard, E. F., Bouaziz-Amar, É., Lacorte, J., et al. (2020) · Biomolecules · doi:10.3390/biom10050810 · Cited by 12
“Note that such an enhanced cholesteryl ester transfer from HDL to triglyceride-rich lipoprotein subspecies has been previously reported in patients presenting primary hypertriglyceridemia [39,40] or during the postprandial phase in subjects with mixed hyperlipidemia [41].”
Background
The association of HDL cholesterol concentration with the −629C>A CETP promoter polymorphism is not fully explained by its relationship with plasma cholesteryl ester transfer
Dullaart, R. P. F., Borggreve, S. E., Hillege, H. L., & Dallinga‐Thie, G. M. (2008) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.1080/00365510701519719 · Cited by 11
“The rate of plasma cholesteryl ester mass transfer between HDL and apo B-containing lipoproteins reflects the action of CETP on HDL in the context of the constellation and composition of endogenous cholesteryl ester acceptor lipoproteins [7].”
Background
Enhancement of cholesteryl ester transfer in plasma by hormone-replacement therapy
Ritsch, A., Kaser, S., Volgger, B., Abfalter, E., Sturm, W., nzer, H. G., ger, B. F., Kirchmair, R., Ebenbichler, C. F., & Patsch, J. R. (2002) · Metabolism · doi:10.1053/meta.2002.31991 · Cited by 11
Fenofibrate reverses the decline in HDL cholesterol in mice overexpressing human phospholipid transfer protein
Lie, J. T., Lankhuizen, I. M., Gross, B. S., vanGent, T., VANHAPEREN, R., Scheek, L. M., Staels, B., DECROM, R., & Vantol, A. (2005) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2005.10.002 · Cited by 12
Plasma triglyceride and high density lipoprotein cholesterol are poor surrogate markers of pro-atherogenic chylomicron remnant homeostasis in subjects with the metabolic syndrome
Irawati, D., Mamo, J. C. L., Dhaliwal, S. S., Soares, M. J., Clark, K., & James, A. P. (2016) · Lipids in Health and Disease · doi:10.1186/s12944-016-0330-4 · Cited by 10
“A defect in lipolysis would be expected to promote an increased residency time for TRLs including chylomicron particles and favour increased lipid exchange promote accumulation of TRL remnants [38, 39].”
Background
Plasma cholesteryl ester transfer protein and lipoprotein levels during treatment of growth hormone‐deficient adult humans
Carrilho, A. J. F., Cunha-Neto, M. B. C., Nunes, V. S., Lottenberg, A. M., Medina, W. L., Nakandakare, E. R., Musolino, N. R. D. C., Bronstein, M. D., & Quintão, E. C. R. (2001) · Lipids · doi:10.1007/s11745-001-0756-y · Cited by 10
Association between Plasma Cholesteryl Ester Transfer Protein activity and Lipid profiles in Metabolic Syndrome in an Iranian Population
Goodarzi, M. T., Mohammadian, M., Borzouei, S., & Hassanzadeh, T. (2014) · Cited by 10
Low‐fat diets, triglycerides and coronary heart disease risk
Roche, H. M. (2000) · Nutrition Bulletin · doi:10.1046/j.1467-3010.2000.00020.x · Cited by 10
Apolipoprotein‐B subclasses as acceptors of cholesteryl esters transferred by CETP
Lee, D. M., Alaupovic, P., Knight‐Gibson, C., & Bagdade, J. D. (2008) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.2008.02001.x · Cited by 10
VLDL-bound lipoprotein lipase facilitates the cholesteryl ester transfer protein-mediated transfer of cholesteryl esters from HDL to VLDL
Pruneta‐Deloche, V., Pulcini, T., Lalanne, F., Marçais, C., Berthézène, F., Ponsin, G., & Moulin, P. (1999) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)32108-8 · Cited by 11
Effect of infusion of a triacylglycerol emulsion on low-density lipoprotein composition and oxidizability
Callow, J., Samra, J. S., & Frayn, K. N. (1998) · Atherosclerosis · doi:10.1016/s0021-9150(97)00261-x · Cited by 9
“Except in severe hypertriglyceridaemia, the rate of CETP-mediated neutral lipid exchange is dependent on the availability of TAG [16].”
Background
LIPID ABNORMALITIES IN PATIENTS OF BETA THALASSAEMIA MAJOR
Patne, A., Hisalkar, P., & Gaikwad, S. (2012) · Cited by 9
Clinical Relevance of Reducing Triglycerides
Nafziger, A. N. (1994) · Drugs · doi:10.2165/00003495-199448010-00001 · Cited by 9
CETP‐mediated cholesteryl ester enrichment of apoB subclasses in type 1 diabetes
Bagdade, J. D., Knight‐Gibson, C., Simpson, N., Gerkin, R. D., Alaupovic, P., & Reardon, C. (2011) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.2011.02636.x · Cited by 8
Effect of dietary omega-3 eicosapentaenoic acid supplements on cholesteryl ester transfer from HDL in cholesterol-fed rabbits
Sugano, M., Makino, N., & Yanaga, T. (1997) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/s0005-2760(97)00013-1 · Cited by 8
Reduced cholesteryl ester transfer in plasma of patients with lipoprotein lipase deficiency.
Bagdade, J. D., Ritter, M. C., Lithell, H., Bassett, D. R., Mailly, F., Talmud, P. J., & Hayden, M. R. (1996) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39112-4 · Cited by 8
Association between the atherogenic index of plasma and coronary collateral circulation in patients with chronic total occlusion
Dong, S., Qiao, J., Gao, A., Zhao, Z., Huang, X., Kan, Y., Yang, Z., Ma, M., Chu, F., Han, H., et al. (2024) · BMC Cardiovascular Disorders · doi:10.1186/s12872-024-03992-y · Cited by 6
“CETP transfers TG from apolipoprotein B lipoprotein particles to HDL-C through TG exchange of cholesterol esters, resulting in a decrease in HDL-C levels and an increase in LDL-C and very low-density lipoprotein cholesterol (VLDL-C) levels in plasma [39].”
Background
Study of high sensitive c-reactive protein in preeclampsia
Aruna, P., Krishnamma, M., Ramalingam, K., Naidu, J. N., & Prasad, M. (2018) · International Journal of Clinical Biochemistry and Research · doi:10.18231/2394-6377.2018.0061 · Cited by 6
“Triacylglycerol levels are a major determinant of cholesterol ester transfer protein (CETP) activity.(10) Therefore, in the presence of increased triacylglycerolrich lipoproteins, CETP activity is increased so that all circulating lipoproteins become enriched in triacylglycerol, in particular HDL and LDL particles.”
Background
Elevated Serum Low-Density Lipoproteins-Cholesterol Levels and B1B2/B2B2 CETP Genotype Are Positively Associated with Nonalcoholic Fatty Liver Disease in Women with Gallstone Disease
Pérez-Robles, M., Campos-Perez, W. Y., Rivera-Valdes, J. J., Franco‐Topete, R. A., Navarrete-Medina, E. M., Maldonado‐González, M., Ruiz‐Madrigal, B., Rodríguez-Reyes, S. C., & Martínez‐López, E. (2022) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2022.0010 · Cited by 6
Epidemiology: Disease Associations and Modulators of HDL-Related Biomarkers
Savolainen, M. J. (2014) · Handbook of experimental pharmacology · doi:10.1007/978-3-319-09665-0_7 · Cited by 6
“The excess triglyceride-rich particles also enhance the CETP-mediated exchange of cholesteryl esters from HDL to apoB-containing lipoprotein particles and simulta- neous transfer of triglycerides into HDL (Mann et al. 1991; Liinamaa et al. 1997).”
Background
Métabolisme des lipides et des lipoprotéines chez l'homme
Gautier, T., Masson, D., & Lagrost, L. (2010) · EMC - Endocrinologie - Nutrition · doi:10.1016/s1155-1941(10)51260-5 · Cited by 6
Characterization of two HDL subfractions and LpA-I, LpA-I:A-II distribution profiles and clinical characteristics of hyperalphalipoproteinemic subjects without cholesterol ester transfer protein deficiency.
Sich, D., Saïdi, Y., Giral, P., Lagrost, L., Dallongeville, J., Federspiel, M.-C., Cherfils, C., Raisonnier, A., Turpin, G., & Beucler, I. (1998) · Atherosclerosis · doi:10.1016/s0021-9150(98)00030-6 · Cited by 6
“CETP activity with exogenous lipoproteins was determined measuring the transfer of [H]CE between donor exogenous [H]CE HDL3 and acceptor exogenous unlabeled LDL [31].”
BackgroundMethod
Postprandial Hyperlipidemia and Coronary Artery Disease
Patsch, J. R. (1993) · Medical science symposia series · doi:10.1007/978-94-011-1703-6_9 · Cited by 6
Cholesteryl ester transfer in patients with renal failure or renal transplants
Corboy, J., Sutherland, W. H. F., Walker, R. J., Robertson, M. C., & COX, C. M. (1994) · Kidney International · doi:10.1038/ki.1994.378 · Cited by 6
“[12—14], and hyperlipidemia accelerates plasma cholesteryl ester transfer [15, 16].”
BackgroundResultInfluential
The Role of a Triplet Repeat Sequence of the Very Low Density Lipoprotein Receptor Gene in Plasma Lipid and Lipoprotein Level Variability in Humans
Helbecque, N., Dallongeville, J., Codron, V., Arveiler, D., Ruidavets, J., Evans, A., Cambien, F., Fruchart, J., & Amouyel, P. (1997) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.17.11.2759 · Cited by 6
Serum Cholesteryl Ester Transfer Protein Concentrations Are Associated with Serum Levels of Total Cholesterol, Beta-Lipoprotein and Apoproteins in Patients with Type 2 Diabetes Mellitus
Inukai, Y., Ito, K., Hara, K., Yamazaki, A., Takebayashi, K., Aso, Y., & Inukai, T. (2007) · Medical Principles and Practice · doi:10.1159/000104810 · Cited by 5
Sex-specific responses in glucose-insulin homeostasis and lipoprotein-lipid components after high-dose supplementation with marine n-3 PUFAs in abdominal obesity: a randomized double-blind crossover study
Laupsa‐Borge, J., Grytten, E., Bohov, P., Bjørndal, B., Strand, E., Skorve, J., Nordrehaug, J. E., Berge, R. K., Rostrup, E., Mellgren, G., et al. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1020678 · Cited by 5
Sphingolipidomic profile and HDL subfractions in obese dyslipidemic type 2 diabetic patients
Aslan, İ., Aydın, D., Koca, Y., Yılmaz, Ç., Çeker, T., Öztüzün, A., & Aslan, M. (2023) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2023.106719 · Cited by 5
HDL and Endothelium
Maranhão, R. C., Filho, A. C. M., Sigal, G. A., Chagas, A. C. P., & da Luz, P. L. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-812348-5.00022-2 · Cited by 5
Modulation of the Activity of the Human Cholesteryl Ester Transfer Protein by Carboxylated Derivatives
Florentin, E., Athias, A., & Lagrost, L. (1996) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1996.0699h.x · Cited by 5
Statins and Fibrates: Should They Be Recommended?
Chruściel, P., Mikhailidis, D. P., Toth, P. P., Rysz, J., & Banach, M. (2015) · Springer eBooks · doi:10.1007/978-3-319-20433-8_2 · Cited by 4
Dyslipidemia and atherogenic indexes in children with transfusion-dependent thalassemia
Ray, S., Saikia, D., Vashisht, Y., Sharma, S., Meena, R. K., & Kumar, M. (2023) · Hematology Transfusion and Cell Therapy · doi:10.1016/j.htct.2023.02.006 · Cited by 4
Association between cholesteryl ester transfer protein Taq1B polymorphism with lipid levels in primary hyperlipidemic patients
Hassanzadeh, T., Firoozrai, M., Zonouz, A. E., & Paoli, M. (2008) · European Journal of Lipid Science and Technology · doi:10.1002/ejlt.200700101 · Cited by 4
One Common Polymorphism of Cholesteryl Ester Transfer Protein Gene in Iranian Subjects With and Without Primary Hypertriglyceridemia
Hassanzadeh, T., Firoozrai, M., Zonouz, A. E., Radmehr, H., Zavarehee, A., & Paoli, M. (2007) · Pakistan Journal of Biological Sciences · doi:10.3923/pjbs.2007.4224.4229 · Cited by 4
Lipid-modifying therapy
(2007) · CRC Press eBooks · doi:10.1201/b13464-10 · Cited by 4
Dyslipidaemia in type 2 diabetes
Adiseshiah, M., Olive, S., & Harrison, Z. (2002) · Primary Health Care · doi:10.7748/phc2002.02.12.1.41.c359 · Cited by 4
Accelerated cholesteryl ester transfer in patients with essential hypertension and the effect of ramipril treatment
Bagdade, J. D., Liu, X.-Q., Buchanan, W., Hafner, J. M., & Rosenson, R. S. (1998) · Atherosclerosis · doi:10.1016/s0021-9150(98)00101-4 · Cited by 4
Assessment of the relationship between insulin resistance, atherogenic index of plasma and white blood cell count: A data mining study
Doğan, H. O. (2017) · Cumhuriyet Tıp Dergisi/Cumhuriyet Üniversitesi Tıp Fakültesi dergisi · doi:10.7197/223.v39i29491.316368 · Cited by 3
Chapter 15 Dynamics of lipoprotein transport in the circulatory system
Fielding, P. E., & Fielding, C. J. (1991) · New comprehensive biochemistry · doi:10.1016/s0167-7306(08)60343-9 · Cited by 3

Authors: Mann, C. J., Yen, F. T., Grant, A. M., & Bihain, B. E.
Affiliations: Louisiana State University (US)
ORCID: Yen, F T
Venue: Journal of Clinical Investigation
Publisher: American Society for Clinical Investigation
Published: 1991-12-01
Volume: 88
Issue: 6
Pages: 2059-2066
ISSN: 0021-9738 (ISSN-L)
DOI: 10.1172/jci115535
OpenAlex: W2114689977
Cited by: 339
References: 30
Citations by year: 2024: 5 · 2023: 3 · 2022: 5 · 2021: 2 · 2020: 1 · 2019: 2 · 2018: 2 · 2017: 3 · 2016: 3 · 2015: 2 · 2014: 10 · 2013: 1 · 2012: 2
FWCI: 17.17
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Journal of Clinical Investigation (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5p01hl025596-15)
National Heart, Lung, and Blood Institute (HL255-96)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipid metabolism and disorders
Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Cholesterol and Lipid Metabolism
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
Keywords: cholesteryl ester transfer, cholesteryl ester transfer protein, hypertriglyceridemia, VLDL, VLDL triglycerides, reverse cholesterol transport, CETP activity, bezafibrate, lipoprotein metabolism, rate-determining step
MeSH terms: Adult, Bezafibrate, Biological Transport, Carrier Proteins, Cholesterol Esters, Glycoproteins, Humans, Lipoproteins, HDL, Lipoproteins, LDL, Lipoproteins, VLDL, Triglycerides, Hypertriglyceridemia, Cholesterol Ester Transfer Proteins

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Mechanism of plasma cholesteryl ester transfer in hypertriglyceridemia.

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