The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.
Impaired diurnal adrenal rhythmicity restored by constant infusion of corticotropin-releasing hormone in corticotropin-releasing hormone-deficient mice.
Open accessAbstract
The normal pattern of daily glucocorticoid production in mammals requires circadian modulation of hypothalamicpituitary-adrenal axis activity. To assess both the factors responsible for imparting this diurnal profile and its physiologic importance, we have exploited corticotropin-releasing hormone (CRH)-deficient mice generated by homologous recombination in embryonic stem cells. CRH-deficient mice have lost normal circadian variations in plasma ACTH and glucocorticoid while maintaining normal circadian locomotor activity. Constant peripheral infusion of CRH produced marked diurnal excursions of plasma glucocorticoid, indicating that CRH acts in part as a permissive factor for other circadian modulators of adrenocortical activity. The presence of atrophic adrenals in CRH-deficient mice without an overt deficit in basal plasma ACTH concentration suggests that the diurnal increase in ACTH is essential to maintain normal adrenal function.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“CRH KO mice also demonstrate this sexual dichotomy in response to stress, indicating a mechanism independent of CRH (12, 38).”
From Interleukin-6 is an essential, corticotropin-releasing hormone-independent stimulator of the adrenal axis during immune system activation (2000) · cites this paper as [38]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Vale, W., Spiess, J., Rivier, C., & Rivier, J. (1981) · Science · doi:10.1126/science.6267699 · Cited by 3,965
Stephan, F. K., & Zucker, I. (1972) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.69.6.1583 · Cited by 2,039
Nemeroff, C. B., Widerlöv, E., Bissette, G., Walléus, H., Karlsson, I., Eklund, K., Kilts, C. D., Loosen, P. T., & Vale, W. (1984) · Science · doi:10.1126/science.6334362 · Cited by 1,485
Vaughan, J. M., Donaldson, C. J., Bittencourt, J. C., Perrin, M. H., Lewis, K., Sutton, S. W., Chan, R. K. W., Turnbull, A. V., Lovejoy, D. A., RIVIER, C. L., et al. (1995) · Nature · doi:10.1038/378287a0 · Cited by 1,479
Dunn, A. J., & Berridge, C. W. (1990) · Brain Research Reviews · doi:10.1016/0165-0173(90)90012-d · Cited by 1,352
Corticosteroid inhibition of acth secretion
KELLER-WOOD, M. E., & DALLMAN, M. F. (1984) · Endocrine Reviews · doi:10.1210/edrv-5-1-1 · Cited by 1,219
Regulation of ACTH Secretion: Variations on a Theme of B
DALLMAN, M. F., AKANA, S. F., CASCIO, C. S., DARLINGTON, D. N., JACOBSON, L., & LEVIN, N. (1987) · Proceedings of the 1986 Laurentian Hormone Conference · doi:10.1016/b978-0-12-571143-2.50010-1 · Cited by 655
Self-citationCorticotropin-releasing hormone deficiency reveals major fetal but not adult glucocorticoid need
Muglia, L., Jacobson, L., Dikkes, P., & Majzoub, J. A. (1995) · Nature · doi:10.1038/373427a0 · Cited by 524
Self-citationModulation of glucose regulation and insulin secretion by circadian rhythmicity and sleep
Van Cauter, E., Blackman, J. D., Roland, D., Spire, J. P., Refetoff, S., & Polonsky, K. S. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115396 · Cited by 448
Food and Water Restriction Shifts Corticosterone, Temperature, Activity and Brain Amine Periodicity
Krieger, D. T. (1974) · Endocrinology · doi:10.1210/endo-95-5-1195 · Cited by 382
Flagged first, then by citations
Cited by
Sorted by citations
Intraadrenal interactions in the regulation of adrenocortical steroidogenesis.
Ehrhart-Bornstein, M., Hinson, J. P., Bornstein, S. R., Scherbaum, W. A., & Vinson, G. P. (1998) · Endocrine Reviews · doi:10.1210/edrv.19.2.0326 · Cited by 600
Role of glucocorticoid negative feedback in the regulation of HPA axis pulsatility
Gjerstad, J. K., Lightman, S. L., & Spiga, F. (2018) · Stress · doi:10.1080/10253890.2018.1470238 · Cited by 437
Gonadal steroid hormones and the hypothalamo–pituitary–adrenal axis
Handa, R. J., & Weiser, M. J. (2014) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2013.11.001 · Cited by 408
Bethin, K. E., Vogt, S. K., & Muglia, L. J. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.16.9317 · Cited by 381
Self-citationHypothalamic-pituitary-adrenocortical axis regulation
Jacobson, L. (2005) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2005.01.003 · Cited by 248
Self-citationThe role of corticotropin-releasing factor and urocortin in the modulation of ingestive behavior
Heinrichs, S. C., & Richard, D. (1999) · Neuropeptides · doi:10.1054/npep.1999.0047 · Cited by 184
Transgenic Approach to the Study of Body Weight Regulation
Inui, A. (2000) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01435-2 · Cited by 159
Williams, J. B., Pang, D., Delgado, B., Kocherginsky, M., Tretiakova, M., Krausz, T., Pan, D., He, J., McClintock, M. K., & Conzen, S. D. (2009) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-08-0238 · Cited by 137
A feedback-controlled ensemble model of the stress-responsive hypothalamo-pituitary-adrenal axis.
Keenan, D. M., Licinio, J., & Veldhuis, J. D. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.051624198 · Cited by 145
Weninger, S. C., Peters, L. L., & Majzoub, J. A. (2000) · Endocrinology · doi:10.1210/endo.141.1.7277 · Cited by 149
Self-citationHypothalamic‐Pituitary‐Adrenocortical Axis: Neuropsychiatric Aspects
Jacobson, L. (2014) · Comprehensive physiology · doi:10.1002/cphy.c130036 · Cited by 153
Self-citationJones, J. R., Chaturvedi, S. M., Granados‐Fuentes, D., & Herzog, E. D. (2021) · Nature Communications · doi:10.1038/s41467-021-25959-9 · Cited by 149
Circadian Clocks, Stress, and Immunity
Dumbell, R., Matveeva, O., & Oster, H. (2016) · Frontiers in Endocrinology · doi:10.3389/fendo.2016.00037 · Cited by 150
Solberg, L. C., Olson, S. L., Turek, F. W., & Redei, E. (2001) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.2001.281.3.r786 · Cited by 145
Di Dalmazi, G., Berr, C. M., Fassnacht, M., Beuschlein, F., & Reincke, M. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2014-1401 · Cited by 139
Corticotropin-releasing hormone regulates IL-6 expression during inflammation
Venihaki, M., Dikkes, P., Carrigan, A., & Karalis, K. P. (2001) · Journal of Clinical Investigation · doi:10.1172/jci12869 · Cited by 135
Corticotropin-releasing hormone and animal models of anxiety: gene–environment interactions
Bakshi, V. P., & Kalin, N. H. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(00)01082-9 · Cited by 126
Placental corticotropin-releasing hormone: Function and regulation
Majzoub, J. A., & Karalis, K. P. (1999) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(99)70708-8 · Cited by 120
Self-citationAdrenal Clocks and the Role of Adrenal Hormones in the Regulation of Circadian Physiology
Leliavski, A., Dumbell, R., Ott, V., & Oster, H. (2014) · Journal of Biological Rhythms · doi:10.1177/0748730414553971 · Cited by 125
Genetic approaches to hypothalamic-pituitary-adrenal axis regulation
Arnett, M. G., Muglia, L. M., Laryea, G., & Muglia, L. J. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2015.215 · Cited by 105
Watts, A. G., Tanimura, S. M., & Sanchez‐Watts, G. (2003) · Endocrinology · doi:10.1210/en.2003-0394 · Cited by 109
Hypothalamic Regulation of Corticotropin-Releasing Factor under Stress and Stress Resilience
Kageyama, K., Iwasaki, Y., & Daimon, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222212242 · Cited by 115
Bornstein, S., WEBSTER, E. L., Torpy, D. J., Richman, S. J., Mitsiades, N., Igel, M., Lewis, D. B., Rice, K. C., Joost, H., Tsokos, M., et al. (1998) · Endocrinology · doi:10.1210/endo.139.4.5938 · Cited by 106
Loss of hypothalamic corticotropin-releasing hormone markedly reduces anxiety behaviors in mice
Zhang, R., Asai, M., Mahoney, C. E., Joachim, M., Shen, Y., Gunner, G., & Majzoub, J. A. (2016) · Molecular Psychiatry · doi:10.1038/mp.2016.136 · Cited by 103
Self-citationBurrows, H. L., Nakajima, M., Lesh, J., Goosens, K. A., Samuelson, L. C., Inui, A., Camper, S. A., & Seasholtz, A. F. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1963 · Cited by 94
Corticotropin-releasing hormone physiology
Majzoub, J. A. (2006) · European Journal of Endocrinology · doi:10.1530/eje.1.02247 · Cited by 97
Self-citationVenihaki, M., Carrigan, A., Dikkes, P., & Majzoub, J. A. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.13.7336 · Cited by 87
Self-citationJeong, K.-H., Jacobson, L., Pacák, K., Widmaier, E. P., Goldstein, D. S., & Majzoub, J. A. (2000) · Endocrinology · doi:10.1210/endo.141.3.7370 · Cited by 87
Self-citationNeuroendocrine underpinnings of sex differences in circadian timing systems
Yan, L., & Silver, R. (2015) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2015.10.007 · Cited by 89
Muglia, L. J., Jacobson, L., Luedke, C., Vogt, S. K., Schaefer, M. L., Dikkes, P., Fukuda, S., Sakai, Y., Suda, T., & Majzoub, J. A. (2000) · Journal of Clinical Investigation · doi:10.1172/jci5250 · Cited by 80
Self-citationDeng, Q., Riquelme, D., Trinh, L., Low, M. J., Tomić, M., Stojilkovic, S., & Aguilera, G. (2015) · Endocrinology · doi:10.1210/en.2015-1265 · Cited by 77
CRH Deficiency Impairs but Does Not Block Pituitary-Adrenal Responses to Diverse Stressors
Jacobson, L., Muglia, L. J., Weninger, S. C., Pacák, K., & Majzoub, J. A. (2000) · Neuroendocrinology · doi:10.1159/000054524 · Cited by 76
Self-citationSolano, J. M., & Jacobson, L. (1999) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1999.277.4.e708 · Cited by 75
Self-citationJeong, K., Jacobson, L., Widmaier, E. P., & Majzoub, J. A. (1999) · Endocrinology · doi:10.1210/endo.140.4.6669 · Cited by 67
Self-citationChronic variable stress alters hypothalamic–pituitary–adrenal axis function in the female mouse
Borrow, A. P., Heck, A. L., Miller, A. M., Sheng, J. A., Stover, S. A., Daniels, R. M., Bales, N. J., Fleury, T. K., & Handa, R. J. (2019) · Physiology & Behavior · doi:10.1016/j.physbeh.2019.112613 · Cited by 68
Torres‐Farfan, C., Serón‐Ferré, M., Dinet, V., & Korf, H. (2005) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2005.00279.x · Cited by 68
Corticotropin-releasing hormone deficiency unmasks the proinflammatory effect of epinephrine
Karalis, K. P., Kontopoulos, E., Muglia, L. J., & Majzoub, J. A. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.12.7093 · Cited by 64
Self-citationRhythmicity matters: Circadian and ultradian patterns of HPA axis activity
Focke, C. M. B., & Iremonger, K. J. (2019) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2019.110652 · Cited by 64
CRH-deficient mice have a normal anorectic response to chronic stress
Weninger, S. C., Muglia, L. J., Jacobson, L., & Majzoub, J. A. (1999) · Regulatory Peptides · doi:10.1016/s0167-0115(99)00070-1 · Cited by 57
Self-citationCorticotropin Secretory Dynamics in Humans under Low Glucocorticoid Feedback
Veldhuis, J. D., Iranmanesh, A., Naftolowitz, D. F., Tatham, N. E., Cassidy, F., & Carroll, B. J. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.11.8046 · Cited by 56
Pituitary-Adrenal Axis Regulation in Crh-Deficient Mice
Muglia, L. J., Bethin, K. E., Jacobson, L., Vogt, S. K., & Majzoub, J. A. (2000) · Endocrine Research · doi:10.3109/07435800009048638 · Cited by 56
Self-citationMice, melatonin and the circadian system
Korf, H., & von Gall, C. (2006) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2006.03.005 · Cited by 54
Jacobson, L. (1999) · Endocrinology · doi:10.1210/endo.140.1.6416 · Cited by 60
Self-citationKvetnansky, R., Kubovcakova, L., Tillinger, A., Micutkova, L., Krizanova, O., & Sabban, E. L. (2006) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-006-9063-7 · Cited by 53
Jacobson, L., Ansari, T., & McGuinness, O. P. (2006) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00383.2005 · Cited by 51
Self-citationAnimal Models of CRH Deficiency
Venihaki, M., & Majzoub, J. A. (1999) · Frontiers in Neuroendocrinology · doi:10.1006/frne.1999.0179 · Cited by 53
Self-citationThe physiology of corticotropin-releasing hormone deficiency in mice
Muglia, L. J., Jacobson, L., Weninger, S. C., Karalis, K. P., Jeong, K., & Majzoub, J. A. (2001) · Peptides · doi:10.1016/s0196-9781(01)00385-0 · Cited by 50
Self-citationMultimodal Regulation of Circadian Glucocorticoid Rhythm by Central and Adrenal Clocks
Son, G. H., Cha, H. K., Chung, S., & Kim, K. (2018) · Journal of the Endocrine Society · doi:10.1210/js.2018-00021 · Cited by 49
Ultradian Cortisol Pulsatility Encodes a Distinct, Biologically Important Signal
McMaster, A., Jangani, M., Sommer, P., Han, N., Brass, A., Beesley, S., Lu, W., Berry, A. A., Loudon, A. S. I., Donn, R. P., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0015766 · Cited by 49
Plasminogen regulates pro‐opiomelanocortin processing
Wang, N., Zhang, L., Miles, L. A., & Hoover-Plow, J. L. (2004) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2004.00694.x · Cited by 46
Targeted mutations of the corticotropin-releasing factor system: effects on physiology and behavior
Contarino, A., & Gold, L. H. (2002) · Neuropeptides · doi:10.1054/npep.2002.0899 · Cited by 44
Sexual Dimorphism in Circadian Physiology Is Altered in LXRα Deficient Mice
Feillet, C. A., Guérin, S., Lonchampt, M., Dacquet, C., Gustafsson, J.-Α., Delaunay, F., & Teboul, M. (2016) · PLoS ONE · doi:10.1371/journal.pone.0150665 · Cited by 43
Genetically engineered mice for studies of stress-related clinical conditions
Müller, M. B., & Keck, M. E. (2002) · Journal of Psychiatric Research · doi:10.1016/s0022-3956(01)00049-8 · Cited by 38
Transgenic study of energy homeostasis equation: implications and confounding influences
Inui, A. (2000) · The FASEB Journal · doi:10.1096/fj.00-0291rev · Cited by 38
Malathion exposure modulates hypothalamic gene expression and induces dyslipedemia in Wistar rats
Rezg, R., Mornagui, B., Ahmed, M. B., Chouchane, S. G., Belhajhmida, N., Abdeladhim, M., Kamoun, A., El‐Fazâa, S., & Gharbi, N. (2010) · Food and Chemical Toxicology · doi:10.1016/j.fct.2010.03.013 · Cited by 37
Langouche, L., Téblick, A., Gunst, J., & den Berghe, G. V. (2023) · Endocrine Reviews · doi:10.1210/endrev/bnad021 · Cited by 40
Lessons from CRH knockout mice
Venihaki, M., & Majzoub, J. A. (2002) · Neuropeptides · doi:10.1054/npep.2002.0906 · Cited by 36
Self-citationKlose, M., Jørgensen, K., & Kristensen, L. Ø. (2004) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2004.02111.x · Cited by 29
Yoshida-Hiroi, M., BRADBURY, M. J., Eisenhofer, G., Hiroi, N., Vale, W., Novotny, G. E. K., Hartwig, H.-G., Scherbaum, W., & Bornstein, S. R. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001143 · Cited by 30
Taste responsiveness and diet preference in autoimmune MRL mice
Ballok, D. A. (2003) · Behavioural Brain Research · doi:10.1016/s0166-4328(02)00276-0 · Cited by 31
Circadian Clocks and the Interaction between Stress Axis and Adipose Function
Kolbe, I., Dumbell, R., & Oster, H. (2015) · International Journal of Endocrinology · doi:10.1155/2015/693204 · Cited by 27
Sollars, P. J., Weiser, M. J., Kudwa, A. E., Bramley, J. R., Ogilvie, M. D., Spencer, R. L., Handa, R. J., & Pickard, G. E. (2014) · PLoS ONE · doi:10.1371/journal.pone.0111944 · Cited by 26
Heinrichs, S. C., & Souza, E. B. D. (1999) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1053/beem.1999.0042 · Cited by 26
Jacobson, L., Ansari, T., Potts, J. E., & McGuinness, O. P. (2006) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00526.2005 · Cited by 24
Self-citationMouse feeding behavior: ethology, regulatory mechanisms and utility for mutant phenotyping
Heinrichs, S. C. (2001) · Behavioural Brain Research · doi:10.1016/s0166-4328(01)00287-x · Cited by 24
Chida, D., Imaki, T., Suda, T., & Iwakura, Y. (2005) · Endocrinology · doi:10.1210/en.2005-0409 · Cited by 24
Kageyama, K., & Suda, T. (2008) · Peptides · doi:10.1016/j.peptides.2008.12.007 · Cited by 23
Nolan, L. A., Windle, R., Wood, S. A., Kershaw, Y. M., Lunness, H. R., Lightman, S. L., Ingram, C. D., & Levy, A. (2000) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.2000.00569.x · Cited by 22
Hypothalamic Regulation of Anterior Pituitary Function
Ben-Shlomo, A., & Melmed, S. K. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-380926-1.10002-1 · Cited by 22
Kubovčáková, L., Mičutková, L., Bartošová, Z., Sabban, E. L., Križanová, O., & Květňanský, R. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.03832.x · Cited by 21
Jeong, K., Sakihara, S., Widmaier, E. P., & Majzoub, J. A. (2004) · Endocrinology · doi:10.1210/en.2003-1558 · Cited by 22
Self-citationGene Regulation System of Vasopressin and Corticotoropin-Releasing Hormone
Yoshida, M. (2008) · Gene Regulation and Systems Biology · doi:10.4137/grsb.s424 · Cited by 20
Jacobson, L. (1999) · Endocrinology · doi:10.1210/endo.140.8.6910 · Cited by 18
Self-citationTéblick, A., Bruyn, L. D., Oudenhove, T. V., Perre, S. V., Pauwels, L., Derde, S., Langouche, L., & den Berghe, G. V. (2021) · Endocrinology · doi:10.1210/endocr/bqab222 · Cited by 19
Fukuda, Y., Kageyama, K., Nigawara, T., Kasagi, Y., & Suda, T. (2004) · Neuroscience Letters · doi:10.1016/j.neulet.2004.06.006 · Cited by 15
Stress-axis, coping and dementia: gene-manipulation studies
Heinrichs, S. C. (1999) · Trends in Pharmacological Sciences · doi:10.1016/s0165-6147(99)01335-8 · Cited by 16
Kageyama, K., Tamasawa, N., & Suda, T. (2011) · Stress · doi:10.3109/10253890.2010.536279 · Cited by 14
Molecular Chaperones and the Epigenetics of Longevity and Cancer Resistance
KRØLL, J. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1395.006 · Cited by 14
Dissecting Adrenal and Behavioral Responses to Stress by Targeted Gene Inactivation in Mice
Brewer, J. A., Bethin, K. E., Schaefer, M. L., Muglia, L. M., Vogt, S. K., Weninger, S. C., Majzoub, J. A., & Muglia, L. J. (2003) · Stress · doi:10.1080/1025389031000116460 · Cited by 12
Self-citationHypothalamic Regulation of Anterior Pituitary Function
Ben-Shlomo, A., & Melmed, S. (2017) · The Pituitary · doi:10.1016/b978-0-12-804169-7.00002-7 · Cited by 11
Nováková, M., Květňanský, R., & Mysliveček, J. (2010) · Stress · doi:10.3109/10253890902849840 · Cited by 10
Molecular Genetic Approaches to the Neuropharmacology of Corticotropin-Releasing Factor
Koob, G. F., Bartfai, T., & Roberts, A. J. (2001) · International Journal of Comparative Psychology · doi:10.46867/c4cp4b · Cited by 9
Soto-Rivera, C. L., & Majzoub, J. A. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-804169-7.00003-9 · Cited by 9
Self-citationLow, M. J. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-29738-7.00007-1 · Cited by 8
Yeh, C.-M. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00436 · Cited by 7
A hypothalamic circuit for circadian regulation of corticosterone secretion
Ramírez‐Plascencia, O. D., Luca, R. D., Machado, N., Eghlidi, D. H., Khanday, M. A., Bandaru, S. S., Raffin, F., Vujović, N., Arrigoni, E., & Saper, C. B. (2026) · Nature Communications · doi:10.1038/s41467-026-71482-0 · Cited by 6
Low, M. J. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4377-0324-5.00007-9 · Cited by 6
Molekulare Grundlagen der Adipositas
Hebebrand, J., Hinney, A., & Oeffner, F. (2001) · Springer eBooks · doi:10.1007/978-3-642-56858-9_12 · Cited by 6
Wang, O., & Majzoub, J. A. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-380926-1.10003-3 · Cited by 5
Self-citationMolecular biology of the HPA axis
Abel, K.-B., & Majzoub, J. A. (2005) · Techniques in the behavioral and neural sciences · doi:10.1016/s0921-0709(05)80008-2 · Cited by 5
Self-citationAssessment of serum level of corticotropin-releasing factor in primary nocturnal enuresis
Motawie, A. A., Al-Aziz, A. M. A., Hamed, H., Fatouh, A. A. A., Awad, M. A. M., & El-Ghany, A. A. (2016) · Journal of Pediatric Urology · doi:10.1016/j.jpurol.2016.08.030 · Cited by 5
Regulation and Actions of Corticotropin‐Releasing Hormone
Weninger, S. C., & Majzoub, J. A. (2001) · Comprehensive physiology · doi:10.1002/cphy.cp070406 · Cited by 5
Self-citationMutagenesis and Knockout Models: Hypothalamic-Pituitary-Adrenocortical System
Keck, M. E., & Müller, M. B. (2005) · Handbook of experimental pharmacology · doi:10.1007/3-540-28082-0_4 · Cited by 4
Genetics of Endocrine-Behavior Interactions
Müller, M. B., Keck, M. E., Steckler, T., & Holsboer, F. (2002) · Elsevier eBooks · doi:10.1016/b978-012532104-4/50093-7 · Cited by 4
Beneš, J., Tománková, H., Nováková, M., Rohan, Z., Květňanský, R., & Mysliveček, J. (2013) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-013-9916-9 · Cited by 3
Neuroendocrinology of Behavioral Rhythms
Lee, T. M., & Smale, L. (2006) · Springer eBooks · doi:10.1007/978-0-387-30405-2_23 · Cited by 3
Lessons Learned from Gene Targeting and Transgenesis for Adrenal Physiology and Disease
Böttner, A., & Bornstein, S. R. (2001) · Reviews in Endocrine and Metabolic Disorders · doi:10.1023/a:1011568516406 · Cited by 3
Hypothalamic Regulation of Anterior Pituitary Function
Ben-Shlomo, A., & Melmed, S. K. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-99899-4.00021-4 · Cited by 2
The future of feed intake regulation research
Baile, C. A., & Della‐Fera, M. A. (2001) · Journal of Animal Science · doi:10.2527/jas2001.79e-supple171x · Cited by 2
Gaston, L. S., Jorgensen, B., Friedman, H., Sherman, M. S., & Majzoub, J. A. (2026) · Endocrinology · doi:10.1210/endocr/bqag081
Self-citation
Metadata
- Authors
- Muglia, L. J., Jacobson, L., Weninger, S. C., Luedke, C. E., Bae, D. S., Jeong, K. H., & Majzoub, J. A.
- Affiliations
- Boston Children's Hospital (US)
- Howard Hughes Medical Institute (US)
- Corresponding author
- Majzoub, J A
- Venue
- Journal of Clinical Investigation
- Published
- 1997-06-15
- Volume
- 99
- Issue
- 12
- Pages
- 2923-2929
- ISSN
- 0021-9738 (ISSN-L)
- PMC
- PMC508144
- OpenAlex
- W1992866860
- Cited by
- 115
- References
- 47
- Citations by year
- 2026: 2 · 2025: 1 · 2023: 1 · 2022: 2 · 2021: 3 · 2019: 2 · 2018: 2 · 2017: 2 · 2016: 6 · 2015: 5 · 2014: 6 · 2013: 2 · 2012: 1
- FWCI
- 5.64
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Clinical Investigation (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Pfizer
- National Alliance for Research on Schizophrenia and Depression
- National Institutes of Health (1p30hd033688-01)
- Pfizer Pharmaceuticals
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD 33688)
- Topics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Keywords
- corticotropin-releasing factor, circadian rhythm, hypothalamic-pituitary-adrenal axis, ACTH, adrenal atrophy, adrenocortical function, glucocorticoid synthesis
- MeSH terms
- Adrenal Cortex, Adrenocorticotropic Hormone, Animals, Blood Glucose, Circadian Rhythm, Corticosterone, Corticotropin-Releasing Hormone, Female, Glucocorticoids, Insulin, Light, Male, Mice, Inbred C57BL, Motor Activity, Photoperiod, Mice, Knockout, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review