C-reactive protein: a critical update

C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women

Ridker, P. M., Hennekens, C. H., Buring, J. E., & Rifai, N. (2000) · New England Journal of Medicine · doi:10.1056/nejm200003233421202 · Cited by 5,850

Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men

Ridker, P. M., Cushman, M., Stampfer, M. J., Tracy, R. P., & Hennekens, C. H. (1997) · New England Journal of Medicine · doi:10.1056/nejm199704033361401 · Cited by 5,504

C-Reactive Protein in Healthy Subjects: Associations With Obesity, Insulin Resistance, and Endothelial Dysfunction: A Potential Role for Cytokines Originating From Adipose Tissue?

Yudkin, J. S., Stehouwer, C. D. A., Emeis, J. J., & Coppack, S. W. (1999) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.19.4.972 · Cited by 2,465

The Prognostic Value of C-Reactive Protein and Serum Amyloid A Protein in Severe Unstable Angina

Liuzzo, G., Biasucci, L. M., Gallimore, J. R., Grillo, R. L., Rebuzzi, A. G., Pepys, M. B., & Maseri, A. (1994) · New England Journal of Medicine · doi:10.1056/nejm199408183310701 · Cited by 2,354

C-Reactive Protein, a Sensitive Marker of Inflammation, Predicts Future Risk of Coronary Heart Disease in Initially Healthy Middle-Aged Men

Köenig, W., Sund, M., Fröhlich, M., Fischer, H.-G., Löwel, H., Döring, A., Hutchinson, W. L., & Pepys, M. B. (1999) · Circulation · doi:10.1161/01.cir.99.2.237 · Cited by 1,952

Hemostatic Factors and the Risk of Myocardial Infarction or Sudden Death in Patients with Angina Pectoris

Thompson, S. G., Kienast, J., Pyke, S., Haverkate, F., & van de Loo, J. C. W. (1995) · New England Journal of Medicine · doi:10.1056/nejm199503093321003 · Cited by 1,819

Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses

Danesh, J. (2000) · BMJ · doi:10.1136/bmj.321.7255.199 · Cited by 1,692

Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events

Ridker, P. M., Rifai, N., Clearfield, M., Downs, J. R., Weis, S. E., Miles, J. S., & Gotto, A. M. (2001) · New England Journal of Medicine · doi:10.1056/nejm200106283442601 · Cited by 1,557

Production of C-reactive protein and risk of coronary events in stable and unstable angina

Haverkate, E., Thompson, S. G., Pyke, S., Gallimore, J. R., & Mark B Pepys Group (1997) · The Lancet · doi:10.1016/s0140-6736(96)07591-5 · Cited by 1,511

Long-Term Effects of Pravastatin on Plasma Concentration of C-reactive Protein

Ridker, P. M., Rifai, N., Pfeffer, M. A., Sacks, F. M., & Braunwald, E. (1999) · Circulation · doi:10.1161/01.cir.100.3.230 · Cited by 1,471

The impact of bariatric surgery on inflammation: quenching the fire of obesity?

Hafida, S., Mirshahi, T., & Nikolajczyk, B. S. (2016) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0000000000000277 · Cited by 53

Associations between cardiovascular disease risk factors and IL-6 and hsCRP levels in the elderly

Nadrowski, P., Chudek, J. T., Skrzypek, M., Puzianowska‐Kuźnicka, M., Mossakowska, M., Więcek, A., Zdrojewski, T. R., Grodzicki, T. K., & Kozakiewicz, K. (2016) · Experimental Gerontology · doi:10.1016/j.exger.2016.10.001 · Cited by 53

Innate immunity, hemostasis and matrix remodeling: PTX3 as a link

Doni, A., Garlanda, C., & Mantovani, A. (2016) · Seminars in Immunology · doi:10.1016/j.smim.2016.10.012 · Cited by 54

C-reactive protein and cold-pressor tolerance in the general population: the Tromsø Study

Schistad, E. I., Stubhaug, A., Furberg, A., Engdahl, B., & Nielsen, C. S. (2017) · Pain · doi:10.1097/j.pain.0000000000000912 · Cited by 53

Is C-Reactive Protein a Prognostic Factor of Colorectal Cancer?

Shiu, Y.-C., Lin, J.-K., Huang, C., Jiang, J., Wang, L.-W., Huang, H., & Yang, S.-H. (2008) · Diseases of the Colon & Rectum · doi:10.1007/s10350-007-9133-z · Cited by 53

The Relationship Between Adrenomedullin, Metabolic Factors, and Vascular Function in Individuals With Type 2 Diabetes

Lim, S. C., Morgenthaler, N. G., Subramaniam, T., Wu, Y. S., Goh, S. K., & Sum, C. F. (2007) · Diabetes Care · doi:10.2337/dc06-1899 · Cited by 54

Anti-Inflammatory and Antioxidant Effects of Liposoluble C60 at the Cellular, Molecular, and Whole-Animal Levels

Hui, M., Jia, X., Li, X., Lazcano-Silveira, R., & Shi, M. (2023) · Journal of Inflammation Research · doi:10.2147/jir.s386381 · Cited by 52

Blood-based biomarkers in patients with non-small cell lung cancer treated with immune checkpoint blockade

Tsai, Y.-T., Schlom, J., & Donahue, R. N. (2024) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-024-02969-1 · Cited by 56

Magnetic chemiluminescent immunoassay for human C-reactive protein on the centrifugal microfluidics platform

Czilwik, G., Vashist, S. K., Klein, V., Buderer, A., Roth, G. D., von Stetten, F., Zengerle, R., & Mark, D. (2015) · RSC Advances · doi:10.1039/c5ra12527h · Cited by 52

C-reactive protein as an early predictor for anastomotic leakage in elective abdominal surgery

Šćepanović, M., Kovačević, B., Cijan, V., Antic, A., Petrovic, Z., Ašćerić, R. R., Krdžić, I., & Cuk, V. V. (2013) · Techniques in Coloproctology · doi:10.1007/s10151-013-1013-z · Cited by 52

Evaluating Chagas disease progression and cure through blood-derived biomarkers: a systematic review

Requena‐Méndez, A., López, M. C., Angheben, A., Izquierdo, L., Ribeiro, I., Pinazo, M., Gascón, J., & Muñóz, J. (2013) · Expert Review of Anti-infective Therapy · doi:10.1586/14787210.2013.824718 · Cited by 52

Limited value of pro-inflammatory oxylipins and cytokines as circulating biomarkers in endometriosis – a targeted ‘omics study

Lee, Y. H., Liang, C., Fang, J., Chern, B. S. M., Tan, H. H., & Chan, J. K. Y. (2016) · Scientific Reports · doi:10.1038/srep26117 · Cited by 52

Electrochemical methods for detection of biomarkers of Chronic Obstructive Pulmonary Disease in serum and saliva

Xuan, C., Dong, T., Wei, X., Yang, Z., Pires, N. M. M., Ren, J., & Jiang, Z. (2019) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2019.111453 · Cited by 52

Sputum and salivary protein biomarkers and point-of-care biosensors for the management of COPD.

Dong, T., Santos, S., Yang, Z.-C., Yang, S., & Kirkhus, N. E. (2020) · In Analysis · doi:10.1039/c9an01704f · Cited by 36

Global assessment of C-reactive protein and health-related outcomes: an umbrella review of evidence from observational studies and Mendelian randomization studies

Markozannes, G., Koutsioumpa, C., Cividini, S., Monori, G., Tsilidis, K. K., Kretsavos, N., Τheodoratou, E., Gill, D., Ioannidis, J. P. A., & Tzoulaki, I. (2020) · European Journal of Epidemiology · doi:10.1007/s10654-020-00681-w · Cited by 52

Endothelial Dysfunction and Neutrophil Degranulation as Central Events in Sepsis Physiopathology

Martín-Fernández, M., Tamayo-Velasco, Á., Aller, R., Gonzalo‐Benito, H., Martínez-Paz, P., & Tamayo, E. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22126272 · Cited by 58

C-Reactive Protein Does Not Directly Induce Tissue Factor in Human Monocytes

Paffen, E., Vos, H. L., & Bertina, R. M. (2004) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000126681.16619.69 · Cited by 52

C-reactive protein (CRP) induces chemokine secretion via CD11b/ICAM-1 interaction in human adherent monocytes

Montecucco, F., Steffens, S., Burger, F., Pelli, G., Monaco, C. G., & Mach, F. (2008) · Journal of Leukocyte Biology · doi:10.1189/jlb.0208123 · Cited by 52

Association of fear of terror with low-grade inflammation among apparently healthy employed adults

Melamed, S., Shirom, A., Toker, S., Berliner, S., & Shapira, I. (2004) · Psychosomatic Medicine · doi:10.1097/01.psy.0000130963.52755.b9 · Cited by 51

Early identification of metabolic syndrome risk: A review of reviews and proposal for defining pre-metabolic syndrome status

Gesteiro, E., Megía, A., Guadalupe‐Grau, A., Fernández‐Veledo, S., Vendrell, J. J., & González‐Gross, M. (2021) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2021.05.022 · Cited by 61

Systemic inflammation, heart rate variability and air pollution in a cohort of senior adults

Luttmann‐Gibson, H., Suh, H. H., Coull, B. A., Dockery, D. W., Sarnat, S. E., Schwartz, J. D., Stone, P. H., & Gold, D. R. (2010) · Occupational and Environmental Medicine · doi:10.1136/oem.2009.050625 · Cited by 51

Effect of Oral and Vaginal Hormonal Contraceptives on Inflammatory Blood Biomarkers

Divani, A. A., Luo, X., Datta, Y. H., Flaherty, J. D., & Panoskaltsis‐Mortari, A. (2015) · Mediators of Inflammation · doi:10.1155/2015/379501 · Cited by 56

Effect of surgeon experience on postoperative plasma cortisol and C ‐reactive protein concentrations after ovariohysterectomy in the dog: a randomised trial

Michelsen, J., Heller, J., Wills, F., & Noble, G. K. (2012) · Australian Veterinary Journal · doi:10.1111/j.1751-0813.2012.01013.x · Cited by 52

Minimally modified electronegative LDL and its autoantibodies in acute and chronic coronary syndromes

de Oliveira, J. A., Sevanian, A., Rodrigues, R. J., Apolinário, E., & Abdalla, D. S. P. (2006) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2006.05.002 · Cited by 51

Biomarkers for ventilator-associated pneumonia: Review of the literature

Palazzo, S. J., Simpson, T., & Schnapp, L. M. (2011) · Heart & Lung · doi:10.1016/j.hrtlng.2010.11.003 · Cited by 51

Clinical relevance of procalcitonin and C-reactive protein as infection markers in renal impairment: a cross-sectional study

Park, J. H., Kim, D. H., Jang, H. R., Kim, M., Jung, S., Lee, J. E., Huh, W., Kim, Y.-G., Kim, D. J., & Oh, H. Y. (2014) · Critical Care · doi:10.1186/s13054-014-0640-8 · Cited by 51

Molecular basis of cancer-therapy-induced cardiotoxicity: introducing microRNA biomarkers for early assessment of subclinical myocardial injury

Sandhu, H., & Maddock, H. L. (2013) · Clinical Science · doi:10.1042/cs20120620 · Cited by 51

Targeted Biomarker Discovery by High Throughput Glycosylation Profiling of Human Plasma Alpha1-Antitrypsin and Immunoglobulin A

Ruhaak, L. R., Koeleman, C. A. M., Uh, H., Stam, J. C., van Heemst, D., Maier, A. B., Houwing‐Duistermaat, J. J., Hensbergen, P. J., Slagboom, P. E., Deelder, A. M., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0073082 · Cited by 51

Interleukin-6 Receptor Gene, Plasma C-Reactive Protein, and Diabetes Risk in Women

Qi, L., Rifai, N., & Hu, F. B. (2008) · Diabetes · doi:10.2337/db08-0968 · Cited by 50

High-Sensitivity C-Reactive Protein Complements Plasma Epstein-Barr Virus Deoxyribonucleic Acid Prognostication in Nasopharyngeal Carcinoma: A Large-Scale Retrospective and Prospective Cohort Study

Tang, L., Li, C.-F., Chen, Q.-Y., Zhang, L., Lai, X.-P., He, Y., Xu, Y.-X.-X., Hu, D.-P., Wen, S.-H., Peng, Y.-T., et al. (2014) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2014.10.005 · Cited by 51

Emerging role of novel biomarkers in the diagnosis of inflammatory bowel disease

Soubières, A. (2016) · World Journal of Gastrointestinal Pharmacology and Therapeutics · doi:10.4292/wjgpt.v7.i1.41 · Cited by 51

Optimization of microfluidic biosensor efficiency by means of fluid flow engineering

Selmi, M., Gazzah, M. H., & Belmabrouk, H. (2017) · Scientific Reports · doi:10.1038/s41598-017-06204-0 · Cited by 51

A Sustained Reduction in Serum Cholinesterase Enzyme Activity Predicts Patient Outcome following Sepsis

Zivkovic, A. R., Decker, S., Zirnstein, A. C., Sigl, A., Schmidt, K., Weigand, M. A., Hofer, S., & Brenner, T. (2018) · Mediators of Inflammation · doi:10.1155/2018/1942193 · Cited by 53

Pubertal Status and Age are Differentially Associated with Inflammatory Biomarkers in Female and Male Adolescents

Stumper, A., Moriarity, D. P., Coe, C. L., Ellman, L. M., Abramson, L. Y., & Alloy, L. B. (2019) · Journal of Youth and Adolescence · doi:10.1007/s10964-019-01101-3 · Cited by 63

HIF1α inhibition facilitates Leflunomide-AHR-CRP signaling to attenuate bone erosion in CRP-aberrant rheumatoid arthritis

Liang, C., Li, J., Lu, C. C., Xie, D., Liu, J., Zhong, C., Wu, X., Dai, R., Zhang, H., Guan, D., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-12163-z · Cited by 51

Dose-response association between C-reactive protein and risk of all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies

Ni, P., Yu, M., Zhang, R., Cheng, C., He, M., Wang, H., Chen, S., & Duan, G. (2020) · Annals of Epidemiology · doi:10.1016/j.annepidem.2020.07.005 · Cited by 51

Biosensors for detecting viral and bacterial infections using host biomarkers: a review

Qureshi, A., & Niazi, J. H. (2020) · The Analyst · doi:10.1039/d0an00896f · Cited by 51

Ultrasensitive Confocal Fluorescence Microscopy of C-Reactive Protein Interacting With FcγRIIa

Manolov, D., Röcker, C., Hombach, V., Nienhaus, G. U., & Torzewski, J. (2004) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000147407.17137.02 · Cited by 51

Native pentameric C-reactive protein displays more potent pro-atherogenic activities in human aortic endothelial cells than modified C-reactive protein

Devaraj, S., Venugopal, S. K., & Jialal, I. (2005) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2005.03.031 · Cited by 51

Relation of Nocturnal Melatonin Levels to C-Reactive Protein Concentration in Patients With ST-Segment Elevation Myocardial Infarction

Domínguez‐Rodríguez, A., García‐González, M. J., Abreu-González, P., Ferrer, J., & Kaski, J. C. (2005) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2005.07.120 · Cited by 51

Val66Met BDNF polymorphism as a vulnerability factor for inflammation-associated depressive symptoms in women with breast cancer

Dooley, L. N., Ganz, P. A., Cole, S. W., Crespi, C. M., & Bower, J. E. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.02.059 · Cited by 50

Utility of C-Reactive Protein Levels for Early Prediction of Dengue Severity in Adults

Chen, C.-C., Lee, I., Liu, J.-W., Huang, S.-Y., & Wang, L. (2015) · BioMed Research International · doi:10.1155/2015/936062 · Cited by 50

Role of biochemical markers in the monitoring of COVID-19 patients

Letelier, P. J., Encina, N. A. M., Morales, P., Riffo, A., Silva, H., Riquelme, I., & Guzmán, N. H. (2020) · Journal of Medical Biochemistry · doi:10.5937/jomb0-29341 · Cited by 54

The Relationship Between C-Reactive Protein and Atherosclerosis Differs on the Basis of Body Mass Index

Gupta, N., de Lemos, J. A., Ayers, C. R., Abdullah, S. M., McGuire, D. K., & Khera, A. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.04.050 · Cited by 51

Topological Localization of Monomeric C-reactive Protein Determines Proinflammatory Endothelial Cell Responses

Li, H., Wang, J., Wu, Y., Zhang, L., Liu, Z.-P., Filep, J. G., Potempa, L. A., Wu, Y., & Ji, S. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.555318 · Cited by 52

Effect of a Mangosteen Dietary Supplement on Human Immune Function: A Randomized, Double-Blind, Placebo-Controlled Trial

Tang, Y., Li, P.-G., Kondo, M., Ji, H., Kou, Y., & Ou, B. (2009) · Journal of Medicinal Food · doi:10.1089/jmf.2008.0204 · Cited by 50

Correlates of C-reactive protein levels in young adults: a population-based cohort study of 3827 subjects in Brazil

Nazmi, A., Oliveira, I. O., & Victora, C. G. (2008) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2008000500003 · Cited by 50

Inhibition of C-Reactive Protein in Morbidly Obese Patients After Laparoscopic Sleeve Gastrectomy

Hakeam, H. A., O’Regan, P. J., Salem, A. M., Bamehriz, F. Y., & Jomaa, L. F. (2008) · Obesity Surgery · doi:10.1007/s11695-008-9729-y · Cited by 50

Taurine Attenuates Hepatic Inflammation in Chronic Alcohol-Fed Rats Through Inhibition of TLR4/MyD88 Signaling

Lin, C.-J., Chiu, C., Chen, Y., Chen, M.-L., Hsu, T., & Tzang, B. (2015) · Journal of Medicinal Food · doi:10.1089/jmf.2014.3408 · Cited by 50

Comparison of Non-Invasive Methods for the Detection of Coronary Atherosclerosis

Bampi, A. T. B. A., Rochitte, C. E., Favarato, D., Lemos, P. A., & da Luz, P. L. (2009) · Clinics · doi:10.1590/s1807-59322009000700012 · Cited by 48

Multiplex Immuno-MALDI-TOF MS for Targeted Quantification of Protein Biomarkers and Their Proteoforms Related to Inflammation and Renal Dysfunction

Gao, J., Meyer, K., Borucki, K., & Ueland, P. M. (2018) · Analytical Chemistry · doi:10.1021/acs.analchem.7b04975 · Cited by 49

The prognostic value of interleukin 6 in multiple chronic diseases and all-cause death: The Multi-Ethnic Study of Atherosclerosis (MESA)

Cainzos‐Achirica, M., Enjuanes, C., Greenland, P., McEvoy, J. W., Cushman, M., Dardari, Z., Nasir, K., Budoff, M. J., Al-Mallah, M. H., Yeboah, J., et al. (2018) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2018.09.034 · Cited by 50

Serum cytokine patterns in first half of pregnancy

Stokkeland, L. M. T., Giskeødegård, G. F., Stridsklev, S., Ryan, L., Steinkjer, B., Tangerås, L. H., Vanky, E., & Iversen, A. (2019) · Cytokine · doi:10.1016/j.cyto.2019.03.013 · Cited by 49

Involvement of circulating inflammatory factors in prognosis and risk of cardiovascular disease

Haybar, H., Shokouhian, M., Bagheri, M., Davari, N., & Saki, N. (2019) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2019.05.010 · Cited by 55

Appetite change profiles in depression exhibit differential relationships between systemic inflammation and activity in reward and interoceptive neurocircuitry

Cosgrove, K. T., Burrows, K., Avery, J. A., Kerr, K. L., DeVille, D. C., Aupperle, R. L., Teague, T. K., Drevets, W. C., & Simmons, W. K. (2019) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.10.006 · Cited by 50

Effect of curcumin on C‐reactive protein as a biomarker of systemic inflammation: An updated meta‐analysis of randomized controlled trials

Gorabi, A. M., Abbasifard, M., Imani, D., Aslani, S., Razi, B., Alizadeh, S., Bagheri‐Hosseinabadi, Z., Sathyapalan, T., & Sahebkar, A. (2021) · Phytotherapy Research · doi:10.1002/ptr.7284 · Cited by 50

Introducing the wide range C-reactive protein (wr-CRP) into clinical use for the detection of microinflammation

Rogowski, O., Vered, Y., Shapira, I., Noach‐Hirsh, M., Zakut, V., & Berliner, S. A. (2005) · Clinica Chimica Acta · doi:10.1016/j.cccn.2005.02.024 · Cited by 50

Inflammation in Relation to Sarcopenia and Sarcopenic Obesity among Older Adults Living with Chronic Comorbidities: Results from the National Health and Nutrition Examination Survey 1999–2006

Karanth, S. D., Washington, C. J., Cheng, T. D., Zhou, D., Leeuwenburgh, C., Braithwaite, D., & Zhang, D. (2021) · Nutrients · doi:10.3390/nu13113957 · Cited by 49

Incremental value of high-sensitivity C-reactive protein and N-terminal pro-B-type natriuretic peptide for the prediction of postoperative cardiac events in noncardiac vascular surgery patients

Goei, D., Hoeks, S. E., Boersma, E. H., Winkel, T. A., Dunkelgrün, M., Flu, W., Schouten, O., Bax, J. J., & Poldermans, D. (2009) · Coronary Artery Disease · doi:10.1097/mca.0b013e3283219e47 · Cited by 49

Protective Effects of Isolated Polyphenolic and Alkaloid Fractions of Ruta graveolens L. on Acute and Chronic Models of Inflammation

Ratheesh, M., Shyni, G. L., Sindhu, G., & Helen, A. (2009) · Inflammation · doi:10.1007/s10753-009-9154-y · Cited by 49

C-reactive protein variations for different chronic somatic disorders

Håheim, L. L., Nafstad, P. H. J., Olsen, I., Schwarze, P. E., & Rønningen, K. S. (2009) · Scandinavian Journal of Public Health · doi:10.1177/1403494809104358 · Cited by 49

Ultrafast molecular motor driven nanoseparation and biosensing

Lard, M., ten Siethoff, L., Kumar, S., Persson, M., Kronnie, G. T., Linke, H., & Månsson, A. (2013) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2013.03.071 · Cited by 49

High-sensitivity C-reactive protein in the exhaled breath condensate and serum in stable and unstable asthma

Ziętkowski, Z., Tomasiak, M. M., Skiepko, R., Mroczko, B., Szmitkowski, M., & Bodzenta­‐Łukaszyk, A. (2008) · Respiratory Medicine · doi:10.1016/j.rmed.2008.10.003 · Cited by 49

Effects of an Antisense Oligonucleotide Inhibitor of C‐Reactive Protein Synthesis on the Endotoxin Challenge Response in Healthy Human Male Volunteers

Noveck, R. J., Stroes, E. S. G., Flaim, J., Baker, B. F., Hughes, S. G., Graham, M. J., Crooke, R. M., & Ridker, P. M. (2014) · Journal of the American Heart Association · doi:10.1161/jaha.114.001084 · Cited by 49

New Biochemical Insights into the Pathogenesis of Osteoarthritis and the Role of Laboratory Investigations in Clinical Assessment

Punzi, L., Oliviero, F., & Plebani, M. (2005) · Critical Reviews in Clinical Laboratory Sciences · doi:10.1080/10408360591001886 · Cited by 49

The Effect of Roux-en-Y vs. Omega-Loop Gastric Bypass on Liver, Metabolic Parameters, and Weight Loss

Kruschitz, R., Wakolbinger, M., Kienbacher, C., Trauner, M. A., Klammer, C., Schindler, K., Langer, F. B., Prager, G., Krebs, M., & Ludvik, B. H. (2016) · Obesity Surgery · doi:10.1007/s11695-016-2083-6 · Cited by 49

Baseline C-Reactive Protein Level Predicts Survival of Early-Stage Lung Cancer: Evidence from a Systematic Review and Meta-Analysis

Leuzzi, G., Galeone, C., Gisabella, M., Duranti, L., Taverna, F., Suatoni, P., Morelli, D., & Pastorino, U. (2016) · Tumori Journal · doi:10.5301/tj.5000522 · Cited by 49

Methotrexate, blood pressure and markers of arterial function in patients with rheumatoid arthritis: a repeated cross-sectional study

Mangoni, A. A., Baghdadi, L. R., Shanahan, E. M., Wiese, M. D., Tommasi, S., Elliot, D. J., & Woodman, R. J. (2017) · Therapeutic Advances in Musculoskeletal Disease · doi:10.1177/1759720x17719850 · Cited by 51

Inflammation and cell-to-cell communication, two related aspects in frailty

Pansarasa, O., Mimmi, M. C., Davin, A., Giannini, M., Guaita, A., & Cereda, C. (2022) · Immunity & Ageing · doi:10.1186/s12979-022-00306-8 · Cited by 47

Adipocytokines, C-Reactive Protein, and Cardiovascular Disease: A Population-Based Prospective Study

Seven, E., Husemoen, L. L. N., Sehested, T. S. G., Ibsen, H., Wachtell, K., Linneberg, A. R., & Jeppesen, J. (2015) · PLoS ONE · doi:10.1371/journal.pone.0128987 · Cited by 50

High‐sensitivity C reactive protein as a biomarker for grading of childhood asthma in relation to clinical classification, induced sputum cellularity, and spirometry

Deraz, T. E., Kamel, T. B., Elkerdany, T. A., & El‐Ghazoly, H. M. A. (2011) · Pediatric Pulmonology · doi:10.1002/ppul.21539 · Cited by 48

Does elevated C-reactive protein cause human atherothrombosis? Novel insights from genetics, intervention trials, and elsewhere

Nordestgaard, B. G. (2009) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e3283307bfe · Cited by 48

Liver proteins as sensor of human malignancies and inflammation

Peracaula, R., Sarrats, A., & Rudd, P. M. (2010) · PROTEOMICS - CLINICAL APPLICATIONS · doi:10.1002/prca.200900170 · Cited by 48

Evaluation of C-reactive protein as an inflammatory biomarker in rabbits for vaccine nonclinical safety studies

Destexhe, É., Prinsen, M. K., van Schöll, I., Kuper, C. F., Garçon, N., Veenstra, S., & Segal, L. M. (2013) · Journal of Pharmacological and Toxicological Methods · doi:10.1016/j.vascn.2013.04.003 · Cited by 48

Pretreatment Serum C-Reactive Protein Levels Predict Benefit From Multimodality Treatment Including Radical Surgery in Malignant Pleural Mesothelioma

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Elevated Serum C-Reactive Protein Relates to Increased Cerebral Myoinositol Levels in Middle-Aged Adults

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