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Cited by 201

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Apoptotic mechanisms in Alzheimer neurofibrillary degeneration: cause or effect?

Open access
Dickson, Dennis W.·2004·Journal of Clinical Investigation

Abstract

Increasing evidence suggests that selective neuronal loss in neurodegenerative diseases involves activation of cysteine aspartyl proteases (caspases), which initiate and execute apoptosis. In Alzheimer disease both extracellular amyloid deposits and intracellular amyloid beta protein may activate caspases, leading to cleavage of nuclear and cytoskeletal proteins, including tau protein. Proteolysis of tau may be critical to neurofibrillary degeneration, which correlates with dementia.

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Crossref · 10.1172/jci200422317

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Metadata

Authors
Dickson, D. W.
Venue
Journal of Clinical Investigation
Published
2004-07-01
Volume
114
Issue
1
Pages
23-27
ISSN
0021-9738 (ISSN-L)
OpenAlex
W1966929153
Cited by
201
References
7
FWCI
9.31
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Apoptotic mechanisms in Alzheimer neurofibrillary degeneration: cause or effect? https://app.cochat.ai/papers/10.1172/jci200422317
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Dickson, D. W. (2004). Apoptotic mechanisms in Alzheimer neurofibrillary degeneration: cause or effect? Journal of Clinical Investigation. https://doi.org/10.1172/jci200422317

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.