Liver fibrosis

Molecular Mechanisms of Stress-Responsive Changes in Collagen and Elastin Networks in Skin

Aziz, J., Shezali, H., Radzi, Z., Yahya, N. A., Abu Kassim, N. H., Czernuszka, J., & Rahman, M. T. (2016) · Skin Pharmacology and Physiology · doi:10.1159/000447017 · Cited by 7,323

The Versatile Role of microRNA-30a in Human Cancer

Wang, C., Yang, X., Chen, Y., & Chen, L. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000471111 · Cited by 3,414

Natural history of liver fibrosis progression in patients with chronic hepatitis C

Poynard, T., Bedossa, P., & Opolon, P. (1997) · The Lancet · doi:10.1016/s0140-6736(96)07642-8 · Cited by 3,011

Nonalcoholic Steatohepatitis

Ludwig, J., Viggiano, T. R., McGill, D. B., & Ott, B. J. (1980) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(24)00530-5 · Cited by 2,903

J. Submicrosc. Cytol. Pathol.

Thomas, A. C., & Campbell, J. H. (2000) · Cited by 2,800

Epithelial-mesenchymal transition and its implications for fibrosis

Kalluri, R., & Neilson, E. G. (2003) · Journal of Clinical Investigation · doi:10.1172/jci20530 · Cited by 2,715

Epithelial-mesenchymal transition and its implications for fibrosis

Kalluri, R., & Neilson, E. G. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200320530 · Cited by 2,171

Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection

Regev, A., Berho, M. E., Jeffers, L. J., Milikowski, C., Molina, E. G., Pyrsopoulos, N., Feng, Z.-Z., Reddy, K. R., & Schiff, E. R. (2002) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2002.06038.x · Cited by 2,078

Hepatogastroenterology

Xu, D., He, X., Chang, Y., Sun, S., Xu, C., & Lin, J. (2012) · Hepatogastroenterology · doi:10.5754/hge12458 · Cited by 1,977

Liver fibrosis – from bench to bedside

Friedman, S. L. (2003) · Journal of Hepatology · doi:10.1016/s0168-8278(02)00429-4 · Cited by 1,780

Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: a prospective study

Imbert‐Bismut, F., Ratziu, V., Piéroni, L., Charlotte, F., Benhamou, Y., & Poynard, T. (2001) · The Lancet · doi:10.1016/s0140-6736(00)04258-6 · Cited by 1,422

Identification of chronic hepatitis C patients without hepatic fibrosis by a simple predictive model

Forns, X., Ampurdanés, S., Llovet, J. M., Aponte, J. Á. N., Quintó, L., Martínez‐Bauer, E., Bruguera, M., Sánchez-Tapias, J. M., & Rodés, J. (2002) · Hepatology · doi:10.1053/jhep.2002.36128 · Cited by 1,123

Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis

Phillips, R. J., Burdick, M. D., Hong, K. M., Lutz, M., Murray, L. A., Xue, Y., Belperio, J. A., Keane, M. P., & Strieter, R. M. (2004) · Journal of Clinical Investigation · doi:10.1172/jci20997 · Cited by 1,071

Hepatic lipocytes: the principal collagen-producing cells of normal rat liver.

Friedman, S. L., Roll, F. J., Boyles, J., & Bissell, D. M. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.24.8681 · Cited by 859

Roles of TGF-beta in hepatic fibrosis

Gressner, A. M. (2002) · Frontiers in bioscience · doi:10.2741/a812 · Cited by 785

Management of Cirrhosis and Ascites

Ginès, P., Cárdenas, A., Arroyo, V., & Rodés, J. (2004) · New England Journal of Medicine · doi:10.1056/nejmra035021 · Cited by 768

History, Heterogeneity, Developmental Biology, and Functions of Quiescent Hepatic Stellate Cells

Geerts, A. (2001) · Seminars in Liver Disease · doi:10.1055/s-2001-17550 · Cited by 740

Nonalcoholic fatty liver disease: Improvement in liver histological analysis with weight loss

Dixon, J. B., Bhathal, P. S., Hughes, N. R., & O'Brien, P. E. (2004) · Hepatology · doi:10.1002/hep.20251 · Cited by 727

Toll-Like Receptor 4 Mediates Inflammatory Signaling by Bacterial Lipopolysaccharide in Human Hepatic Stellate Cells

Paik, Y.-H., Schwabe, R. F., Bataller, R., Russo, M. P., Jobin, C., & Brenner, D. A. (2003) · Hepatology · doi:10.1053/jhep.2003.50182 · Cited by 651

Cooperation of Liver Cells in Health and Disease

Kmieć, Z. (2001) · Advances in anatomy, embryology and cell biology · doi:10.1007/978-3-642-56553-3 · Cited by 645

Evaluation of Liver Fibrosis: A Concise Review

Afdhal, N. H., & Nunes, D. (2004) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2004.30110.x · Cited by 614

Projecting future complications of chronic hepatitis C in the United States

Davis, G. L., Albright, J. E., Cook, S. F., & Rosenberg, D. M. (2003) · Liver Transplantation · doi:10.1053/jlts.2003.50073 · Cited by 577

NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis

Bataller, R. A., Schwabe, R. F., Choi, Y. H., Yang, L., Paik, Y. H., Lindquist, J. N., Qian, T., Schoonhoven, R., Hagedorn, C. H., Lemasters, J. J., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci18212 · Cited by 566

Apoptosis: The nexus of liver injury and fibrosis

Canbay, A. E., Friedman, S. L., & Gores, G. J. (2004) · Hepatology · doi:10.1002/hep.20051 · Cited by 536

Hepatic Stellate Cells as a Target for the Treatment of Liver Fibrosis

Bataller, R. A., & Brenner, D. A. (2001) · Seminars in Liver Disease · doi:10.1055/s-2001-17558 · Cited by 493

NADPH oxidase–derived free radicals are key oxidants in alcohol-induced liver disease

Kono, H., Rusyn, I., Yin, M., Gäbele, E., Yamashina, S., Dikalova, A., Kadiiska, M. B., Connor, H. D., Mason, R. P., Segal, B. H., et al. (2000) · Journal of Clinical Investigation · doi:10.1172/jci9020 · Cited by 493

Angiotensin II induces contraction and proliferation of human hepatic stellate cells

Bataller, R. A., Ginès, P., Nicolás, J. M., Görbig, M. N., García-Ramallo, E., Gasull, X., Bosch, J., Arroyo, V., & Rodés, J. (2000) · Gastroenterology · doi:10.1016/s0016-5085(00)70368-4 · Cited by 490

Fibrogenesis II. Metalloproteinases and their inhibitors in liver fibrosis

Arthur, M. J. P. (2000) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.2000.279.2.g245 · Cited by 479

Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin

Kamada, Y., Tamura, S., Kiso, S., Matsumoto, H., Saji, Y., Yoshida, Y., Fukui, K., Maeda, N., Nishizawa, H., Nagaretani, H., et al. (2003) · Gastroenterology · doi:10.1053/j.gastro.2003.08.029 · Cited by 479

Effects of platelet-derived growth factor and other polypeptide mitogens on DNA synthesis and growth of cultured rat liver fat-storing cells.

Pinzani, M., Gesualdo, L., Sabbah, G. M., & Abboud, H. E. (1989) · Journal of Clinical Investigation · doi:10.1172/jci114363 · Cited by 477

Spontaneous recovery from micronodular cirrhosis: Evidence for incomplete resolution associated with matrix cross-linking☆

Issa, R., Zhou, X., Constandinou, C. M., Fallowfield, J. A., Millward‐Sadler, H., Gaça, M. D. A., Sands, E., Suliman, I., Trim, N., & Knorr, A. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.03.009 · Cited by 454

Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro

Galli, A., Crabb, D. W., Ceni, E., Salzano, R., Mello, T., Svegliati–Baroni, G., Ridolfi, F., Trozzi, L., Surrenti, C., & Casini, A. (2002) · Gastroenterology · doi:10.1053/gast.2002.33666 · Cited by 440

A significant proportion of myofibroblasts are of bone marrow origin in human liver fibrosis☆

Forbes, S. J., Russo, F. P., Rey, V., Burra, P., Rugge, M., Wright, N. A., & Alison, M. R. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.02.025 · Cited by 434

Regression of liver fibrosis after biliary drainage in patients with chronic pancreatitis and stenosis of the common bile duct

Hammel, P., Couvelard, A., O'Toole, D., Ratouis, A., Sauvanet, A., Fléjou, J. F., Degott, C., Belghiti, J., Bernades, P., Valla, D., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejm200102083440604 · Cited by 427

Noninvasive diagnosis of liver cirrhosis using DNA sequencer–based total serum protein glycomics

Callewaert, N., Vlierberghe, H. V., Hecke, A. V., Laroy, W., Delanghe, J., & Contreras, R. (2004) · Nature Medicine · doi:10.1038/nm1006 · Cited by 418

Ligands of peroxisome proliferator-activated receptor γ modulate profibrogenic and proinflammatory actions in hepatic stellate cells

Marra, F., Efsen, E., Romanelli, R. G., Caligiuri, A., Pastacaldi, S., Batignani, G., Bonacchi, A., Caporale, R., Laffi, G., Pinzani, M., et al. (2000) · Gastroenterology · doi:10.1053/gast.2000.9365 · Cited by 409

Roles of TGF-beta in hepatic fibrosis

Axel, M. G. (2002) · Frontiers in bioscience · doi:10.2741/gressner · Cited by 407

Host genetic factors influence disease progression in chronic hepatitis C

Powell, E. E., Edwards-Smith, C. J., Hay, J. L., Clouston, A. D., Crawford, D. H., Shorthouse, C., Purdie, D. M., & Jonsson, J. R. (2000) · Hepatology · doi:10.1053/he.2000.6253 · Cited by 397

Leptin receptor–mediated signaling regulates hepatic fibrogenesis and remodeling of extracellular matrix in the rat

Ikejima, K., Takei, Y., Honda, H., Hirose, M., Yoshikawa, M., Zhang, Y., Lang, T., Fukuda, T., Yamashina, S., Kitamura, T., et al. (2002) · Gastroenterology · doi:10.1053/gast.2002.32995 · Cited by 386

II. Alcoholic liver injury involves activation of Kupffer cells by endotoxin

Thurman, R. G. (1998) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.1998.275.4.g605 · Cited by 378

Smad7 prevents activation of hepatic stellate cells and liver fibrosis in rats

Dooley, S., Hamzavi, J., Breitkopf, K., Wiercinska, E., Said, H. M., Lorenzen, J., ten Dijke, P., & Gressner, A. M. (2003) · Gastroenterology · doi:10.1016/s0016-5085(03)00666-8 · Cited by 370

Genetic Polymorphisms and the Progression of Liver Fibrosis: A Critical Appraisal

Bataller, R. A., North, K. E., & Brenner, D. A. (2003) · Hepatology · doi:10.1053/jhep.2003.50127 · Cited by 356

Activated human hepatic stellate cells express the renin-angiotensin system and synthesize angiotensin II

Bataller, R. A., Sancho‐Bru, P., Ginès, P., Lora, J. M., Al-Garawi, A. A., Solé, M., Colmenero, J., Nicolás, J. M., Jiménez, W., Weich, N. S., et al. (2003) · Gastroenterology · doi:10.1016/s0016-5085(03)00695-4 · Cited by 352

Rat hepatic lipocytes express smooth muscle actin upon activation in vivo and in culture.

Rockey, D. C., Boyles, J. K., Gabbiani, G., & Friedman, S. L. (1992) · PubMed · Cited by 342

Rat liver myofibroblasts and hepatic stellate cells: Different cell populations of the fibroblast lineage with fibrogenic potential

Knittel, T. E., Kobold, D., Saile, B., Grundmann, A., Neubauer, K., Piscaglia, F., & Ramadori, G. P. (1999) · Gastroenterology · doi:10.1016/s0016-5085(99)70407-5 · Cited by 338

Strain-specific differences in mouse hepatic wound healing are mediated by divergent T helper cytokine responses

Shi, Z., Wakil, A. E., & Rockey, D. C. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.20.10663 · Cited by 310

Neutrophil-derived superoxide anion induces lipid peroxidation and stimulates collagen synthesis in human hepatic stellate cells: Role of nitric oxide

Casini, A., Ceni, E., Salzano, R., Biondi, P., Parola, M., Galli, A., Foschi, M., Caligiuri, A., Pinzani, M., & Surrenti, C. (1997) · Hepatology · doi:10.1002/hep.510250218 · Cited by 302

Fas enhances fibrogenesis in the bile duct ligated mouse: A link between apoptosis and fibrosis

Canbay, A. E., Higuchi, H., Bronk, S. F., Taniai, M., Sebo, T. J., & Gores, G. J. (2002) · Gastroenterology · doi:10.1053/gast.2002.35953 · Cited by 302

Angiotensin-Converting Enzyme Inhibition Attenuates the Progression of Rat Hepatic Fibrosis

Jonsson, J. R., Clouston, A. D., Ando, Y., Kelemen, L., Horn, M. J., Adamson, M., Purdie, D. M., & Powell, E. E. (2001) · Gastroenterology · doi:10.1053/gast.2001.25480 · Cited by 296

Liver biopsy: complications and risk factors

Thampanitchawong, P. (2000) · World Journal of Gastroenterology · doi:10.3748/wjg.v5.i4.301 · Cited by 294

Histological course of alcoholic hepatitis

Parés, A. R., Caballería, J., Bruguera, M., Torres, M., & Rodés, J. (1986) · Journal of Hepatology · doi:10.1016/s0168-8278(86)80006-x · Cited by 293

Hepatic Stellate Cells: Unique Characteristics in Cell Biology and Phenotype

Sato, M., Suzuki, S., & Senoo, H. (2003) · Cell Structure and Function · doi:10.1247/csf.28.105 · Cited by 292

DDR2 receptor promotes MMP-2–mediated proliferation and invasion by hepatic stellate cells

Olaso, E., Ikeda, K., Eng, F. J., Xu, L.-M., Wang, L., Lin, H. C., & Friedman, S. L. (2001) · Journal of Clinical Investigation · doi:10.1172/jci200112373 · Cited by 291

Hepatic fibrosis

Pópper, H., & Udenfriend, S. (1970) · The American Journal of Medicine · doi:10.1016/s0002-9343(70)80135-8 · Cited by 284

Isolated hepatic lipocytes and kupffer cells from normal human liver: Morphological and functional characteristics in primary culture

Friedman, S. L., Rockey, D. C., McGuire, R. F., Maher, J. J., Boyles, J. K., & Yamasaki, G. (1992) · Hepatology · doi:10.1002/hep.1840150211 · Cited by 284

Is liver fibrosis reversible?

Benyon, R. C., & Iredale, J. P. (2000) · Gut · doi:10.1136/gut.46.4.443 · Cited by 260

The Role of Smad3 in Mediating Mouse Hepatic Stellate Cell Activation

Schnabl, B., Kweon, Y. O., Frederick, J. P., Wang, X.-F., Rippe, R. A., & Brenner, D. A. (2001) · Hepatology · doi:10.1053/jhep.2001.25349 · Cited by 256

Differentiation and function of Kupffer cells

Naito, M., Hasegawa, G., Ebe, Y., & Yamamoto, T. (2004) · Medical Molecular Morphology · doi:10.1007/s00795-003-0228-x · Cited by 252

Human Hepatic Stellate Cells Express CCR5 and RANTES to Induce Proliferation and Migration

Schwabe, R. F., Bataller, R., & Brenner, D. A. (2003) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00215.2003 · Cited by 252

Hepatitis C virus core and nonstructural proteins induce fibrogenic effects in hepatic stellate cells

Bataller, R. A., Paik, Y., Lindquist, J. N., Lemasters, J. J., & Brenner, D. A. (2004) · Gastroenterology · doi:10.1053/j.gastro.2003.11.018 · Cited by 251

The role of kupffer cell oxidant production in early ethanol-induced liver disease,

Wheeler, M. D. (2001) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(01)00748-1 · Cited by 249

A dual reporter gene transgenic mouse demonstrates heterogeneity in hepatic fibrogenic cell populations

Magness, S. T., Bataller, R. A., Yang, L., & Brenner, D. A. (2004) · Hepatology · doi:10.1002/hep.20427 · Cited by 246

PDGF and signal transduction in hepatic stellate cells

Pinzani, M. (2002) · Frontiers in bioscience · doi:10.2741/a875 · Cited by 239

Immune stimulation of hepatic fibrogenesis by CD8 cells and attenuation by transgenic interleukin-10 from hepatocytes

Safadi, R., Ohta, M., Alvarez, C. E., Fiel, M. I., Bansal, M., Mehal, W. Z., & Friedman, S. L. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.04.062 · Cited by 239

Reversibility of liver fibrosis and cirrhosis following treatment for hepatitis C

Arthur, M. J. P. (2002) · Gastroenterology · doi:10.1053/gast.2002.33367 · Cited by 238

Contribution of obesity to hepatitis C-related fibrosis progression

Ortiz, V., Berenguer, M., Rayón, J. M., Carrasco, D., & Berenguer, J. (2002) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2002.05995.x · Cited by 233

Tissue inhibitor of metalloproteinases-1 attenuates spontaneous liver fibrosis resolution in the transgenic mouse

Yoshiji, H., Kuriyama, S., Yoshii, J., Ikenaka, Y., Noguchi, R., Nakatani, T., Tsujinoue, H., Yanase, K., Namisaki, T., Imazu, H., et al. (2002) · Hepatology · doi:10.1053/jhep.2002.35625 · Cited by 229

Hepatocyte-specific disruption of Bcl-xL leads to continuous hepatocyte apoptosis and liver fibrotic responses

Takehara, T., Tatsumi, T., Suzuki, T., Rucker, E. B., Hennighausen, L. G., Jinushi, M., Miyagi, T., Kanazawa, Y., & Hayashi, N. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.07.019 · Cited by 223

Human Hepatic Stellate Cells Show Features of Antigen-Presenting Cells and Stimulate Lymphocyte Proliferation

Viñas, O., Bataller, R., Sancho-Bru, P., Ginès, P., Berenguer, C., Enrich, C., Nicolás, J. M., Ercilla, G., Gallart, T., Vives, J., et al. (2003) · Hepatology · doi:10.1002/hep.1840380418 · Cited by 223

Hepatic fibrogenesis requires sympathetic neurotransmitters

Oben, J. A., Roskams, T., Yang, S., Lin, H., Sinelli, N., Torbenson, M., Smedh, U., Moran, T. H., Li, Z., Huang, J., et al. (2004) · Gut · doi:10.1136/gut.2003.026658 · Cited by 215

Chemokines in liver inflammation and fibrosis

Marra, F. (2002) · Frontiers in bioscience · doi:10.2741/a887 · Cited by 214

Cathepsin B inactivation attenuates hepatic injury and fibrosis during cholestasis

Canbay, A. E., Guicciardi, M. E., Higuchi, H., Feldstein, A. E., Bronk, S. F., Rydzewski, R. M., Taniai, M., & Gores, G. J. (2003) · Journal of Clinical Investigation · doi:10.1172/jci17740 · Cited by 210

Hepatitis C and liver fibrosis

Schuppan, D., Schulze-Krebs, A., Bauer, M. W., & Hahn, E. G. (2003) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401163 · Cited by 209

Portal tract fibrogenesis in the liver

Ramadori, G. P., & Saile, B. (2003) · Laboratory Investigation · doi:10.1038/labinvest.3700030 · Cited by 201

The Pathogenesis of Nonalcoholic Steatohepatitis and Other Fatty Liver Diseases: A Four-Step Model including the Role of Lipid Release and Hepatic Venular Obstruction in the Progression to Cirrhosis

Wanless, I. R., & Shiota, K. (2004) · Seminars in Liver Disease · doi:10.1055/s-2004-823104 · Cited by 200

Interactions Between Hepatic Stellate Cells and the Immune System

Maher, J. J. (2001) · Seminars in Liver Disease · doi:10.1055/s-2001-17555 · Cited by 198

Noninvasive monitoring of patients with chronic hepatitis C

Fontana, R. J., & Lok, A. S.-F. (2002) · Hepatology · doi:10.1053/jhep.2002.36800 · Cited by 196

Procollagen expression by nonparenchymal rat liver cells in experimental biliary fibrosis

Milani, S., Herbst, H., Schuppan, D., Kim, K. Y., Riecken, E. O., & Stein, H. (1990) · Gastroenterology · doi:10.1016/0016-5085(90)91307-r · Cited by 192

Transcriptional regulation of hepatic stellate cell activation: Figure 1

Mann, D. A., & Smart, D. E. (2002) · Gut · doi:10.1136/gut.50.6.891 · Cited by 191

Up-regulation of components of the renin-angiotensin system in the bile duct–ligated rat liver

Paizis, G., Cooper, M. E., Schembri, J. M., Tikellis, C., Burrell, L. M., & Angus, P. (2002) · Gastroenterology · doi:10.1053/gast.2002.36561 · Cited by 189

Cathepsin B inactivation attenuates hepatic injury and fibrosis during cholestasis

Canbay, A. E., Guicciardi, M. E., Higuchi, H., Feldstein, A. E., Bronk, S. F., Rydzewski, R. M., Taniai, M., & Gores, G. J. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200317740 · Cited by 188

Hepatic stellate cells and the regulation of liver inflammation

Marra, F. (1999) · Journal of Hepatology · doi:10.1016/s0168-8278(99)80327-4 · Cited by 187

Relaxin inhibits effective collagen deposition by cultured hepatic stellate cells and decreases rat liver fibrosis in vivo

Williams, E. J., Benyon, R. C., Trim, N., Hadwin, R. J., Grove, B. H., Arthur, M. J. P., Unemori, E., & Iredale, J. P. (2001) · Gut · doi:10.1136/gut.49.4.577 · Cited by 186

HEPATIC FIBROSIS

Albanis, E., & Friedman, S. L. (2001) · Clinics in Liver Disease · doi:10.1016/s1089-3261(05)70168-9 · Cited by 184

SOCS1 Is a Suppressor of Liver Fibrosis and Hepatitis-induced Carcinogenesis

Yoshida, T., Ogata, H., Kamio, M., Joo, A., Shiraishi, H., Tokunaga, Y., Sata, M., Nagai, H., & Yoshimura, A. (2004) · The Journal of Experimental Medicine · doi:10.1084/jem.20031675 · Cited by 184

Liver nbsp fibrosis signals leading to the amplification of the fibrogenic hepatic stellate cell

Rippe, R. A. (2003) · Frontiers in bioscience · doi:10.2741/887 · Cited by 183

Genetic polymorphisms of alcohol metabolizing enzymes

Agarwal, D. P. (2001) · Pathologie Biologie · doi:10.1016/s0369-8114(01)00242-5 · Cited by 182

Upregulation of osteopontin expression is involved in the development of nonalcoholic steatohepatitis in a dietary murine model

Sahai, A., Malladi, P., Melin-Aldana, H., Green, R. M., & Whitington, P. F. (2004) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00002.2004 · Cited by 181

Interleukin 6/Gp130–Dependent Pathways Are Protective During Chronic Liver Diseases

Streetz, K. L., Tacke, F., Leifeld, L., Wüstefeld, T., Graw, A., Klein, C., Kamino, K., Spengler, U., Kreipe, H. H., Kubicka, S., et al. (2003) · Hepatology · doi:10.1053/jhep.2003.50268 · Cited by 168

An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis

Cho, J., Hocher, B., Herbst, H., Jia, J., Ruehl, M., Hahn, E. G., Riecken, E. O., & Schuppan, D. (2000) · Gastroenterology · doi:10.1016/s0016-5085(00)70370-2 · Cited by 167

Role of fibroblast growth factor type 1 and 2 in carbon tetrachloride-induced hepatic injury and fibrogenesis

Yu, C., Wang, F., Jin, C., Huang, X., Miller, D. L., Basilico, C., & McKeehan, W. L. (2003) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)63522-5 · Cited by 167

Extracellular signal-regulated kinase activation differentially regulates platelet-derived growth factor's actions in hepatic stellate cells, and is induced by In Vivo liver injury in the rat

Marra, F., Arrighi, M. C., Fazi, M., Caligiuri, A., Pinzani, M., Romanelli, R. G., Efsen, E., Laffi, G., & Geñtilini, P. (1999) · Hepatology · doi:10.1002/hep.510300406 · Cited by 160

Effect of angiotensin II type 1 receptor blockade on experimental hepatic fibrogenesis

Paizis, G., Gilbert, R. E., Cooper, M. E., Murthi, P., Schembri, J. M., Wu, L. L., Rumble, J. R., Kelly, D. J., Tikellis, C., Cox, A. J., et al. (2001) · Journal of Hepatology · doi:10.1016/s0168-8278(01)00146-5 · Cited by 157

NF-kappaB Inhibits Expression of the alpha1(I) Collagen Gene

Rippe, R. A., Schrum, L. W., Stefanovic, B., Solis-Herruzo, J. A., & Brenner, D. A. (1999) · DNA and Cell Biology · doi:10.1089/104454999314890 · Cited by 156

CD40 Activates NF-κB and c-Jun N-Terminal Kinase and Enhances Chemokine Secretion on Activated Human Hepatic Stellate Cells

Schwabe, R. F., Schnabl, B., Kweon, Y. O., & Brenner, D. A. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.11.6812 · Cited by 155

Promoter Polymorphism of the Cd14 Endotoxin Receptor Gene As A Risk Factor for Alcoholic Liver Disease

Järveläinen, H. A., Orpana, A., Perola, M., Savolainen, V. T., Karhunen, P. J., & Lindros, K. O. (2001) · Hepatology · doi:10.1053/jhep.2001.24236 · Cited by 149

Conditional Tetracycline–Regulated Expression of Tgf–β1 in Liver of Transgenic Mice Leads to Reversible Intermediary Fibrosis

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Prolonged infusion of angiotensin II into normal rats induces stellate cell activation and proinflammatory events in liver

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