The DOI matches its Crossref record; 115 of the 115 references it cites were found in a registry or an index.
ATP-sensitive potassium channelopathies: focus on insulin secretion
Open accessAbstract
ATP-sensitive potassium (K(ATP)) channels, so named because they are inhibited by intracellular (ATP), play key physiological roles in many tissues. In pancreatic beta cells, these channels regulate glucose-dependent insulin secretion and serve as the target for sulfonylurea drugs used to treat type 2 diabetes. This review focuses on insulin secretory disorders, such as congenital hyperinsulinemia and neonatal diabetes, that result from mutations in K(ATP) channel genes. It also considers the extent to which defective regulation of K(ATP) channel activity contributes to the etiology of type 2 diabetes.
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Cites
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Hibino, H., Inanobe, A., Furutani, K., Murakami, S., Findlay, I., & Kurachi, Y. (2010) · Physiological Reviews · doi:10.1152/physrev.00021.2009 · Cited by 1,539
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Metadata
- Authors
- Ashcroft, F. M.
- Venue
- Journal of Clinical Investigation
- Published
- 2005-08-01
- Volume
- 115
- Issue
- 8
- Pages
- 2047-2058
- ISSN
- 0021-9738 (ISSN-L)
- OpenAlex
- W2038353863
- Cited by
- 623
- References
- 115
- FWCI
- 32.35
- Type
- journal article
- Language
- en
- Open access
- bronze
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