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Liver X receptor β in the hippocampus: A potential novel target for the treatment of major depressive disorder?

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Prenatal cannabinoid exposure and altered neurotransmission

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Neuroimmmune interactions of cannabinoids in neurogenesis: focus on interleukin-1β (IL-1β) signalling

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Delta-9-tetrahydrocannabinol disrupts hippocampal neuroplasticity and neurogenesis in trained, but not untrained adolescent Sprague-Dawley rats

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Chronic cannabinoid exposure reduces phencyclidine-induced schizophrenia-like positive symptoms in adult rats

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The Synthetic Cannabinoids THJ-2201 and 5F-PB22 Enhance In Vitro CB1 Receptor-Mediated Neuronal Differentiation at Biologically Relevant Concentrations

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Dual pharmacological inhibitor of endocannabinoid degrading enzymes reduces depressive-like behavior in female rats

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The Endocannabinoid System and Invertebrate Neurodevelopment and Regeneration

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On the Crucial Cerebellar Wound Healing-Related Pathways and Their Cross-Talks after Traumatic Brain Injury in Danio rerio

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15-Deoxy-Δ12,14-Prostaglandin J2 Biphasically Regulates the Proliferation of Mouse Hippocampal Neural Progenitor Cells by Modulating the Redox State

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Long-Term Stress and Concomitant Marijuana Smoke Exposure Affect Physiology, Behavior and Adult Hippocampal Neurogenesis

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Maternal Exposure and Neonatal Effects of Drugs of Abuse

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Neuroanatomical substrates involved in cannabinoid modulation of defensive responses

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From an Alternative Medicine to a New Treatment for Refractory Epilepsies: Can Cannabidiol Follow the Same Path to Treat Neuropsychiatric Disorders?

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Colocalization of CB1 receptors with L1 and GAP-43 in forebrain white matter regions during fetal rat brain development: Evidence for a role of these receptors in axonal growth and guidance

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Down‐regulation of diacylglycerol lipase‐α during neural stem cell differentiation: Identification of elements that regulate transcription

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Impairments in Neurogenesis Are Not Tightly Linked to Depressive Behavior in a Transgenic Mouse Model of Alzheimer's Disease

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The gut microbiome and adult hippocampal neurogenesis: A new focal point for epilepsy?

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Mitogen‐ and stress‐activated kinases regulate progenitor cell proliferation and neuron development in the adult dentate gyrus

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Antiglucocorticoids, Neurogenesis and Depression

Fitzsimons, C. P., van Hooijdonk, L. W. A., Morrow, J. A., Peeters, B. W. M. M., Hamilton, N. M., Craighead, M. W., & Vreugdenhil, E. (2009) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/138955709787316001 · Cited by 19

A cell population that strongly expresses the CB1 cannabinoid receptor in the ependyma of the rat spinal cord

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Role of FOXC1 in regulating APSCs self-renewal via STI-1/PrPC signaling

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Endocannabinoid signaling in glioma

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Unexpected short- and long-term effects of chronic adolescent HU-210 exposure on emotional behavior

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Cannabinoid receptor signaling induces proliferation but not neurogenesis in the mouse olfactory epithelium

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Role of cannabinoid receptor 1 and the peroxisome proliferator-activated receptor α in mediating anti-nociceptive effects of synthetic cannabinoids and a cannabinoid-like compound

Alsalem, M., Haddad, M., Aldossary, S. A., Kalbouneh, H., Altarifi, A., Jaffal, S. M., Abbas, M. A., Aldaoud, N., & El‐Salem, K. (2019) · Inflammopharmacology · doi:10.1007/s10787-019-00584-7 · Cited by 20

Interaction of Cannabis Use and Aging: From Molecule to Mind

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The Public Health Effects of Legalizing Marijuana

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Neuromodulation in Parkinson’s disease targeting opioid and cannabinoid receptors, understanding the role of NLRP3 pathway: a novel therapeutic approach

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Effects of psychedelics on neurogenesis and broader neuroplasticity: a systematic review

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CB 1 receptor signalling mediates cannabidiol-induced panicolytic-like effects and defensive antinociception impairment in mice threatened by Bothrops jararaca lancehead pit vipers

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Subregion‐specific decreases in hippocampal serotonin transporter protein expression and function associated with endophenotypes of depression

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Electroacupuncture Reduces Anxiety Associated With Inflammatory Bowel Disease By Acting on Cannabinoid CB1 Receptors in the Ventral Hippocampus in Mice

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Modulatory Activity of the Endocannabinoid System in the Development and Proliferation of Cells in the CNS

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Presynaptic α2-adrenoceptors control the inhibitory action of presynaptic CB1 cannabinoid receptors on prefrontocortical norepinephrine release in the rat

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Hippocampal Neurogenesis

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Cannabinoid Signaling in Auditory Function and Development

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Canabinoides sintéticos: drogas de abuso emergentes

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Cannabinoids & Stress: Impact of HU-210 on behavioral tests of anxiety in acutely stressed mice

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Colocalization of cannabinoid receptor 1 with somatostatin and neuronal nitric oxide synthase in rat brain hippocampus

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Huntington's disease and neurogenesis: FGF-2 to the rescue?

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Neurorestorative process, law, and mechanisms

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Notch1 signaling contributes to the oncogenic effect of HBx on human hepatic cells

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The Mental Health Industrial Complex: A Study in Three Cases

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Cannabidiol promotes neurogenesis in the dentate gyrus during an abstinence period in rats following chronic exposure to methamphetamine

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Directed growth and differentiation of stem cells towards neural cell fates using soluble and surface-mediated cues

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Effects of cannabinoids and related fatty acids upon the viability of P19 embryonal carcinoma cells

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Learning and memory retention deficits in prepubertal guinea pigs prenatally exposed to low levels of the organophosphorus insecticide malathion

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Long-term effects of THC exposure on reward learning and motivated behavior in adolescent and adult male rats

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The Diels–Alder Approach to Δ9‐Tetrahydrocannabinol Derivatives

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Expectancies about the Effects of Cannabis Use on Eating Disorder Symptoms

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Effects of the synthetic cannabinoid XLR-11 on the viability and migration rates of human brain microvascular endothelial cells in a clinically-relevant model

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Endocannabinoid system in the neurodevelopment of GABAergic interneurons: implications for neurological and psychiatric disorders

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Whole Organisms or Pure Compounds? Entourage Effect Versus Drug Specificity

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New Approaches to the Pharmacological Management of Major Depressive Disorder

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Cannabinoid rescue of striatal progenitor cells in chronic Borna Disease viral encephalitis in rats

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Activation of the p11/SMARCA3/Neurensin-2 pathway in parvalbumin interneurons mediates the response to chronic antidepressants

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Molecular Targets of Cannabinoids Associated with Depression

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Nicotine (NC)-induced "depressive" behavioral symptoms and effects of antidepressants including cannabinoids (CBs)

Hayase, T. (2008) · The Journal of Toxicological Sciences · doi:10.2131/jts.33.555 · Cited by 13

Genetic Manipulation of sn-1-Diacylglycerol Lipase and CB 1 Cannabinoid Receptor Gain-of-Function Uncover Neuronal 2-Linoleoyl Glycerol Signaling in Drosophila melanogaster

Tortoriello, G., Beiersdorf, J., Romani, S., Williams, G. H., Cameron, G. A., Mackie, K., Williams, M. J., Marzo, V. D., Keimpema, E., Doherty, P., et al. (2020) · Cannabis and Cannabinoid Research · doi:10.1089/can.2020.0010 · Cited by 14

Endocannabinoid Regulation of Monoamines in Psychiatric and Neurological Disorders

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Cannabinoid type 2 receptor inhibition enhances the antidepressant and proneurogenic effects of physical exercise after chronic stress

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Role of Cannabinoid Receptors in Anxiety Disorders

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Cannabis, Cannabinoids, and the Association with Psychosis

Radhakrishnan, R., Addy, P. H., Sewell, R. A., Skosnik, P. D., Ranganathan, M., & D’Souza, D. C. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-418679-8.00014-9 · Cited by 12

Serotonin, the Prefrontal Cortex, and the Antidepressant-Like Effect of Cannabinoids

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Effects of Chronic, Low-Dose Cannabinoids, Cannabidiol, Delta-9-Tetrahydrocannabinol and a Combination of Both, on Amyloid Pathology in the 5xFAD Mouse Model of Alzheimer's Disease

Arnanz, M. A., Esteban, S. R. D. M., Martínez-Relimpio, A. M., Rimmerman, N., Zaks, N., Grande, M. T., & Romero, J. (2023) · Cannabis and Cannabinoid Research · doi:10.1089/can.2023.0101 · Cited by 12

Attention Deficit Hyperactivity Disorder, Cannabis Use, and the Endocannabinoid System: A Scoping Review

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Converging action of alcohol consumption and cannabinoid receptor activation on adult hippocampal neurogenesis

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Cannabinoids as Regulators of Neural Development and Adult Neurogenesis

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The Endocannabinoid System is a Major Player in Schizophrenia

Köfalvi, A., & Fritzsche, M. (2007) · Springer eBooks · doi:10.1007/978-0-387-74349-3_22 · Cited by 10

Cannabidiol/cannabidiolic acid-rich hemp (Cannabis sativa L.) extract attenuates cognitive impairments and glial activations in rats exposed to chronic stress

Kamsrijai, U., Charoensup, R., Jaidee, W., Hawiset, T., Thaweethee-Sukjai, B., & Praman, S. (2024) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2024.119113 · Cited by 9

Chronic exposure to a synthetic cannabinoid alters cerebral brain metabolism and causes long-lasting behavioral deficits in adult mice

Bouter, C., Ott, F. W., Günther, D., Weig, L., Schmitz-Peiffer, F., Rozyyeva, M., Beindorff, N., & Bouter, Y. (2023) · Journal of Neural Transmission · doi:10.1007/s00702-023-02607-8 · Cited by 9

Women are taking the hit: Examining the unique consequences of cannabis use across the female lifespan

Gräfe, E. L., Reid, H. M. O., Shkolnikov, I., Conway, K., Kit, A., Acosta, C., & Christie, B. R. (2023) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2023.101076 · Cited by 10

High on Life? Medical Marijuana Laws and SuicidePreprint

Anderson, D. M., Rees, D. I., & Sabia, J. J. (2012) · SSRN Electronic Journal · doi:10.2139/ssrn.1994343 · Cited by 9

Effects of Cannabidiol (CBD) on Doxorubicin-Induced Anxiety and Depression-like Behaviors and mRNA Expression of Inflammatory Markers in Rats

Poudel, B., Bany, B. M., Hales, D. B., & Cheatwood, J. L. (2024) · Brain Sciences · doi:10.3390/brainsci14100999 · Cited by 8

Neurogenesis in the Damaged Mammalian Brain

Nakafuku, M., & Grande, A. W. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-397265-1.00074-5 · Cited by 8

CB1 cannabinoid receptor ligands augment the antidepressant-like activity of biometals (magnesium and zinc) in the behavioural tests

Wośko, S., Serefko, A., Szopa, A., Właź, P., Wróbel, A., Właź, A., Górska, J., & Poleszak, E. (2018) · Journal of Pharmacy and Pharmacology · doi:10.1111/jphp.12880 · Cited by 8

A Role for the Cannabinoid 1 Receptor in Neuronal Differentiation of Adult Spinal Cord Progenitors in vitro is Revealed through Pharmacological Inhibition and Genetic Deletion

Sideris, A., Bekker, T., Chan, W. S., Montoya-Gacharna, J. V., Blanck, T. J. J., & Recio‐Pinto, E. (2012) · Frontiers in Neuroscience · doi:10.3389/fnins.2012.00004 · Cited by 8

Fellutamide B Synthetic Path Intermediates with in Vitro Neuroactive Function Shows Mood-Elevating Effect in Stress-Induced Zebrafish Model

Reddy, R. G., Dachavaram, S. S., Reddy, B. R., Kalyankar, K. B., Rajan, W. D., Kootar, S., Kumar, A., Das, S. K., & Chakravarty, S. (2018) · ACS Omega · doi:10.1021/acsomega.8b00456 · Cited by 7

Cannabinoid receptor subtype influence on neuritogenesis in human SH-SY5Y cells

Lyons, E. L., Leone‐Kabler, S., Kovach, A. L., Thomas, B. F., & Howlett, A. C. (2020) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2020.103566 · Cited by 8

The highs and the lows: Recreational marijuana laws and mental health treatment

Ortega, A. (2023) · Health Economics · doi:10.1002/hec.4726 · Cited by 7

The Neuroprotective Properties, Functions, and Roles of Cannabis sativa in Selected Diseases Related to the Nervous System

Mahdi, O., Baharuldin, M. T. H., Nor, N. H. M., Chiroma, S. M., Jagadeesan, S., & Moklas, M. A. M. (2021) · Central Nervous System Agents in Medicinal Chemistry · doi:10.2174/1871524921666210127110028 · Cited by 6

The Role of Cannabinoids in CNS Development: Focus on Proliferation and Cell Death

Bockmann, E. C., Brito, R., Madeira, L. F., Sampaio, L. D. S., Reis, R. A. D. M., França, G. R., & Calaza, K. D. C. (2022) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-022-01263-y · Cited by 8

High hopes for CB2 receptors in neurogenesis

Downer, E. J. (2013) · British Journal of Pharmacology · doi:10.1111/bph.12548 · Cited by 7

Economics of Suicide

Marcotte, D. E., & Zejcirovic, D. (2020) · Springer eBooks · doi:10.1007/978-3-319-57365-6_132-1 · Cited by 8

Enhanced sensitivity of the MRL/MpJ mouse to the neuroplastic and behavioral effects of acute and chronic antidepressant treatments.

Balu, D. T. (2010) · Experimental and Clinical Psychopharmacology · doi:10.1037/a0017295 · Cited by 7

Unravelling a potential therapeutic effect of polymeric lipid-core nanoencapsulated cannabidiol on anxiety- and panic-like behaviours elicited by Bothrops jararaca lancehead pit vipers

Rodrigues, B. M. D. P., Hernandes, P. M., Balvedi, R. C., Alves, H. F. M., da Silva, K. P., Bicudo, R. D. C., Eberhardt, M. J., Poletto, F. S., Paese, K., Guterres, S. S., et al. (2025) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2025.125747 · Cited by 7

Neurotransmitters Play as a Key Role in Adult Neurogenesis

Hajali, V., Moradi, H. R., & Negah, S. S. (2018) · The Neuroscience Journal of Shefaye Khatam · doi:10.29252/shefa.6.4.61 · Cited by 6

3-Hydroxypropane-1,2-Diyl Dipalmitoleate—A Natural Compound with Dual Roles (CB1 Agonist/FAAH1 Blocker) in Inhibiting Ovarian Cancer Cell Line

Sathynathan, C. V., Lakshmisundaram, R., Sivamurugan, V., Kumar, D. T., Panchatcharam, T. S., Narasimhan, G., Doss, C. G. P., & Gnanambal, K. M. E. (2021) · Pharmaceuticals · doi:10.3390/ph14030255 · Cited by 6

Inhibition of Adult Neurogenesis in Male Mice after Repeated Exposure to Paracetamol Overdose

Suárez, J., de Ceglia, M., Rodríguez-Pozo, M., Vargas, A., Santos, I., Melgar‐Locatelli, S., Castro‐Zavala, A., Castilla‐Ortega, E., de Fonseca, F. R., Decara, J. M., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25041964 · Cited by 5

Hormetic effects of a cannabinoid system component, 2-arachidonoyl glycerol, on cell viability and expression profile of growth factors in cultured mouse Sertoli cells: Friend or foe of male fertility?

Mohammadpour-Asl, S., Roshan‐Milani, S., Fard, A. A., & Golchin, A. (2024) · Reproductive Toxicology · doi:10.1016/j.reprotox.2024.108575 · Cited by 6

Recent Advances in LC–MS/MS Analysis of Δ9-Tetrahydrocannabinol and its Metabolites in Biological Matrices

Ferreirós, N. (2013) · Bioanalysis · doi:10.4155/bio.13.218 · Cited by 6

The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system

Campos, A. C., Ortega, Z., Palazuelos, J., Fogaça, M. V., Aguiar, D. C., Díaz-Alonso, J., Ortega-Gutiérrez, S., Vázquez-Villa, H., Moreira, F. A., Guzmán, M., et al. (2013) · International Journal of Neuropsychopharmacology · doi:10.1017/s1461145712001502 · Cited by 313

Sex, drugs, and adult neurogenesis: Sex‐dependent effects of escalating adolescent cannabinoid exposure on adult hippocampal neurogenesis, stress reactivity, and amphetamine sensitization

Lee, T. T. ‐., Wainwright, S. R., Hill, M. N., Galea, L. A. M., & Gorzalka, B. B. (2013) · Hippocampus · doi:10.1002/hipo.22221 · Cited by 56

The Pro-neurogenic Effects of Cannabidiol and Its Potential Therapeutic Implications in Psychiatric Disorders

Luján, M. Á., & Valverde, O. (2020) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2020.00109 · Cited by 35

Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis

Wolf, S. A., Bick-Sander, A., Fabel, K., Leal-Galicia, P., Tauber, S., Ramirez-Rodriguez, G., Müller, A., Melnik, A., Waltinger, T. P., Ullrich, O., et al. (2010) · Cell Communication and Signaling · doi:10.1186/1478-811x-8-12 · Cited by 208

Open Access

Wolf, S. A., Bick-s, A., Fabel, K. S., Leal-galicia, P., Tauber, S., Ramirez, G., Müller, A., Melnik, A., Waltinger, T. P., Ullrich, O., et al. (2013)