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Cited by 358

The DOI matches its Crossref record; 80 of the 80 references it cites were found in a registry or an index.

Structure and function of the platelet integrin IIb 3

Open access
Bennett, J. S.·2005·Journal of Clinical Investigation

Abstract

The platelet integrin alpha(IIb)beta(3) is required for platelet aggregation. Like other integrins, alpha(IIb)beta(3) resides on cell surfaces in an equilibrium between inactive and active conformations. Recent experiments suggest that the shift between these conformations involves a global reorganization of the alpha(IIb)beta(3) molecule and disruption of constraints imposed by the heteromeric association of the alpha(IIb) and beta(3) transmembrane and cytoplasmic domains. The biochemical, biophysical, and ultrastructural results that support this conclusion are discussed in this Review.

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Metadata

Authors
Bennett, J. S.
Venue
Journal of Clinical Investigation
Published
2005-12-01
Volume
115
Issue
12
Pages
3363-3369
ISSN
0021-9738 (ISSN-L)
OpenAlex
W2050701385
Cited by
358
References
80
FWCI
8.86
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Structure and function of the platelet integrin IIb 3. https://app.cochat.ai/papers/10.1172/jci26989
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Bennett, J. S. (2005). Structure and function of the platelet integrin IIb 3. Journal of Clinical Investigation. https://doi.org/10.1172/jci26989

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.