The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.
Lymphocytes, neuropeptides, and genes involved in alopecia areata
Open accessAbstract
Many lessons in autoimmunity - particularly relating to the role of immune privilege and the interplay between genetics and neuroimmunology - can be learned from the study of alopecia areata, the most common cause of inflammation-induced hair loss. Alopecia areata is now understood to represent an organ-restricted, T cell-mediated autoimmune disease of hair follicles. Disease induction is associated with collapse of hair follicle immune privilege in both humans and in animal models. Here, the role of HLA associations, other immunogenetic factors, and neuroendocrine parameters in alopecia areata pathogenesis are reviewed. This instructive and clinically significant model disease deserves more widespread interest in the immunology community.
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Cites
Loss of Functional Suppression by CD4+CD25+ Regulatory T Cells in Patients with Multiple Sclerosis
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NALP1 in Vitiligo-Associated Multiple Autoimmune Disease
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Neuroimmunology of Stress: Skin Takes Center Stage
Arck, P. C., Slominski, A., Theoharides, T. C., Peters, E. M. J., & Paus, R. (2006) · Journal of Investigative Dermatology · doi:10.1038/sj.jid.5700104 · Cited by 472
Self-citationSee no evil, hear no evil, do no evil: the lessons of immune privilege
Niederkorn, J. Y. (2006) · Nature Immunology · doi:10.1038/ni1328 · Cited by 447
The human hair follicle immune system: cellular composition and immune privilege
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Neuroimmunoendocrine circuitry of the ‘brain-skin connection’
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Cited by
Gilhar, A., Etzioni, A., & Paus, R. (2012) · New England Journal of Medicine · doi:10.1056/nejmra1103442 · Cited by 609
Self-citationKey role of CRF in the skin stress response system
Slominski, A. T., Zmijewski, M. A., Zbytek, B., Tobin, D. J., Theoharides, T. C., & Rivier, J. (2013) · Endocrine Reviews · doi:10.1210/er.2012-1092 · Cited by 400
(Neuro-)endocrinology of epithelial hair follicle stem cells
Paus, R., Arck, P., & Tiede, S. (2008) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2008.02.023 · Cited by 47
Self-citationScreening for associated autoimmune disorders in Polish patients with Addison’s disease
Fichna, M., Fichna, P., Gryczyńska, M., Walkowiak, J., Żurawek, M., & Sowiński, J. (2010) · Endocrine · doi:10.1007/s12020-010-9312-x · Cited by 47
Metadata
- Authors
- Gilhar, A., Paus, R., & Kalish, R. S.
- Venue
- Journal of Clinical Investigation
- Published
- 2007-08-01
- Volume
- 117
- Issue
- 8
- Pages
- 2019-2027
- ISSN
- 0021-9738 (ISSN-L)
- OpenAlex
- W1985141915
- Cited by
- 306
- References
- 54
- FWCI
- 19.30
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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