Alopecia areata
Abstract
This review article synthesizes relevant information about hair-follicle biology and pathobiology and summarizes the clinical presentation and management of this common condition.
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The hair follicle is an immune-privileged organ that can be maintained by POMC-derived peptides including MSH and perhaps cortisol.
“The HF is considered an immune privilege organ that can also be maintained by POMC-derived peptides including melanocyte stimulating hormone (MSH) [129, 180, 181] and perhaps cortisol [59, 182].”
From Steroidogenesis in the skin: Implications for local immune functions (2013) · cites this paper as [180]
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- Authors
- Gilhar, A., Etzioni, A., & Paus, R.
- Affiliations
- Technion – Israel Institute of Technology (IL)
- University of Manchester (GB)
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2012-04-19
- Volume
- 366
- Issue
- 16
- Pages
- 1515-1525
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W4245220598
- Cited by
- 609
- References
- 82
- Citations by year
- 2026: 68 · 2025: 51 · 2024: 46 · 2023: 60 · 2022: 55 · 2021: 51 · 2020: 32 · 2019: 32 · 2018: 40 · 2017: 26 · 2016: 46 · 2015: 33 · 2014: 30 · 2013: 29 · 2012: 9
- FWCI
- 6.07
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Research Explorer (The University of Manchester) (submittedVersion)
- Topics
- Health Sciences › Medicine › Urology › Hair Growth and Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › melanin and skin pigmentation
- Health Sciences › Medicine › Epidemiology › Nail Diseases and Treatments
- Keywords
- alopecia areata, hair follicle biology, clinical features, disease management
- MeSH terms
- Alopecia Areata, Dermatitis, Contact, Hair, Humans, Immunosuppressive Agents, Immunotherapy, Injections, Intralesional, Hair Follicle
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