FGF23 induces left ventricular hypertrophy

Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization

Go, A. S., Chertow, G. M., Fan, D., McCulloch, C. E., & Hsu, C.-Y. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa041031 · Cited by 11,369

Recommendations for Chamber Quantification: A Report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, Developed in Conjunction with the European Association of Echocardiography, a Branch of the European Society of Cardiology

Lang, R. M., Bierig, M., Devereux, R. B., Flachskampf, F. A., Foster, E., Pellikka, P. A., Picard, M. H., Roman, M. J., Seward, J., Shanewise, J. S., et al. (2005) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2005.10.005 · Cited by 11,318

Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart study

Levy, D., Garrison, R. J., Savage, D. D., Kannel, W. B., & Castelli, W. P. (1990) · New England Journal of Medicine · doi:10.1056/nejm199005313222203 · Cited by 5,699

Prevalence of Chronic Kidney Disease in the United States

Coresh, J., Selvin, E., Stevens, L. A., Manzi, J., Kusek, J. W., Eggers, P., Van Lente, F., & Levey, A. S. (2007) · JAMA · doi:10.1001/jama.298.17.2038 · Cited by 4,895

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

Kuro-o, M., Matsumura, Y., Aizawa, H., Kawaguchi, H., Suga, T., Utsugi, T., Ohyama, Y., Kurabayashi, M., Kaname, T., Kume, E., et al. (1997) · Nature · doi:10.1038/36285 · Cited by 3,837

A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy

Molkentin, J. D., Lu, J., Antos, C. L., Markham, B. E., Richardson, J. A., Robbins, J. M., Grant, S. R., & Olson, E. N. (1998) · Cell · doi:10.1016/s0092-8674(00)81573-1 · Cited by 2,566

Fibroblast growth factors.

Ornitz, D. M., & Itoh, N. (2001) · Genome biology · doi:10.1186/gb-2001-2-3-reviews3005 · Cited by 1,985

Cellular signaling by fibroblast growth factor receptors

Eswarakumar, V. P., Lax, I., & Schlessinger, J. (2005) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2005.01.001 · Cited by 1,923

Regulation of cardiac hypertrophy by intracellular signalling pathways

Heineke, J., & Molkentin, J. D. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1983 · Cited by 1,890

Receptor Specificity of the Fibroblast Growth Factor Family

Ornitz, D. M., Xu, J., Colvin, J. S., McEwen, D. G., MacArthur, C. A., Coulier, F., Gao, G., & Goldfarb, M. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.25.15292 · Cited by 1,871

Klotho converts canonical FGF receptor into a specific receptor for FGF23

Urakawa, I., Yamazaki, Y., Shimada, T., Iijima, K., Hasegawa, H., Okawa, K., Fujita, T., Fukumoto, S., & Yamashita, T. (2006) · Nature · doi:10.1038/nature05315 · Cited by 1,865

Fibroblast Growth Factor 23 and Mortality among Patients Undergoing Hemodialysis

Gutiérrez, O. M., Mannstadt, M., Isakova, T., Rauh‐Hain, J. A., Tamez, H. E., Shah, A., Smith, K. T., Lee, H., Thadhani, R., Jüppner, H., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0706130 · Cited by 1,729

Cardiac Hypertrophy: The Good, the Bad, and the Ugly

Frey, N., & Olson, E. N. (2003) · Annual Review of Physiology · doi:10.1146/annurev.physiol.65.092101.142243 · Cited by 1,480

Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia

Shimada, T., Mizutani, S., Muto, T., Yoneya, T., Hino, R., Takeda, S., Takeuchi, Y., Fujita, T., Fukumoto, S., & Yamashita, T. (2001) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.101545198 · Cited by 1,391

Regulation of Fibroblast Growth Factor-23 Signaling by Klotho

Kurosu, H., Ogawa, Y., Miyoshi, M., Yamamoto, M., Nandi, A., Rosenblatt, K. P., Baum, M. G., Schiavi, S. C., Hu, M. C., Moe, O. W., et al. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.c500457200 · Cited by 1,381

NFAT Signaling

Crabtree, G. R., & Olson, E. N. (2002) · Cell · doi:10.1016/s0092-8674(02)00699-2 · Cited by 1,323

Clinical and echocardiographic disease in patients starting end-stage renal disease therapy

Foley, R. N., Parfrey, P. S., Harnett, J. D., Kent, G. M., Martin, C. J., Murray, D. C., & Barré, P. E. (1995) · Kidney International · doi:10.1038/ki.1995.22 · Cited by 1,294

Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney disease

Isakova, T., on behalf of the Chronic Renal Insufficiency Cohort (CRIC) Study Group, WAHL, P. W., Vargas, G. S., Gutiérrez, O. M., Scialla, J. J., Xie, H., Appleby, D. H., Nessel, L. C., Bellovich, K. A., et al. (2011) · Kidney International · doi:10.1038/ki.2011.47 · Cited by 1,271

Receptor Specificity of the Fibroblast Growth Factor Family

Zhang, X., Ibrahimi, O. A., Olsen, S. K., Umemori, H., Mohammadi, M., & Ornitz, D. M. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m601252200 · Cited by 1,164

Cardiac repair with intramyocardial injection of allogeneic mesenchymal stem cells after myocardial infarction

Amado, L. C., SALIARIS, A. P., Schuleri, K. H., John, M. S., Xie, J.-S., Cattaneo, S. M., Durand, D. J., Fitton, T. P., Kuang, J. Q., Stewart, G. C., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504388102 · Cited by 1,072

Fibroblast Growth Factor 23 and Risks of Mortality and End-Stage Renal Disease in Patients With Chronic Kidney Disease

Isakova, T. (2011) · JAMA · doi:10.1001/jama.2011.826 · Cited by 1,023

The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A

Faul, C., Donnelly, M., Merscher, S., Chang, Y. H., Franz, S., Delfgaauw, J., Chang, J., Choi, H. Y., Campbell, K. N., Kim, K., et al. (2008) · Nature Medicine · doi:10.1038/nm.1857 · Cited by 993

The parathyroid is a target organ for FGF23 in rats

Ben‐Dov, I. Z., Galitzer, H., Lavi-Moshayoff, V., Goetz, R. M., Kuro‐o, M., Mohammadi, M., Sirkis, R., Naveh‐Many, T., & Silver, J. (2007) · Journal of Clinical Investigation · doi:10.1172/jci32409 · Cited by 951

Klotho Deficiency Causes Vascular Calcification in Chronic Kidney Disease

Hu, M. C., Shi, M., Zhang, J., Quiñones, H., Griffith, C. S., Kuro‐o, M., & Moe, O. W. (2010) · Journal of the American Society of Nephrology · doi:10.1681/asn.2009121311 · Cited by 945

Fibroblast Growth Factor-23 Mitigates Hyperphosphatemia but Accentuates Calcitriol Deficiency in Chronic Kidney Disease

Gutiérrez, O. M., Isakova, T., Rhee, E. P., Shah, A., Holmes, J., Collerone, G., Diaeresis]ppner, H. J., & Wolf, M. S. (2005) · Journal of the American Society of Nephrology · doi:10.1681/asn.2005010052 · Cited by 920

Immunochemical analysis of myosin heavy chain during avian myogenesis in vivo and in vitro.

Bader, D. M., Masaki, Τ., & Fischman, D. A. (1982) · The Journal of Cell Biology · doi:10.1083/jcb.95.3.763 · Cited by 919

Fibroblast Growth Factor 23 in Oncogenic Osteomalacia and X-Linked Hypophosphatemia

Jonsson, K. B., Zahradnik, R. J., Larsson, T. E., White, K. E., Sugimoto, T., Imanishi, Y., Yamamoto, T., Hampson, G., Koshiyama, H., Ljunggren, Ö., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa020881 · Cited by 904

Fibroblast Growth Factor 23 and Left Ventricular Hypertrophy in Chronic Kidney Disease

Gutiérrez, O. M., Januzzi, J. L., Isakova, T., Laliberte, K. A., Smith, K., Collerone, G., Sarwar, A., Hoffmann, U., Coglianese, E. E., Christenson, R. H., et al. (2009) · Circulation · doi:10.1161/circulationaha.108.844506 · Cited by 843

The MEK1–ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice

Bueno, O. F., Windt, L. J. D., Tymitz, K. M., Witt, S. A., Kimball, T. R., Klevitsky, R., Hewett, T. E., Jones, S. P., Lefer, D. J., Peng, C., et al. (2000) · The EMBO Journal · doi:10.1093/emboj/19.23.6341 · Cited by 774

The Chronic Renal Insufficiency Cohort (CRIC) Study

Feldman, H. I., Appel, L. J., Chertow, G. M., Cifelli, D., Čižman, B., Daugirdas, J. T., Fink, J. C., Franklin-Becker, E. D., Go, A. S., Hamm, L. L., et al. (2003) · Journal of the American Society of Nephrology · doi:10.1097/01.asn.0000070149.78399.ce · Cited by 660

The conserved phosphoinositide 3‐kinase pathway determines heart size in mice

Shioi, T., Kang, P., Douglas, P., Hampe, J., Yballe, C., Lawitts, J., Cantley, L., & Izumo, S. (2000) · EMBO Journal · doi:10.1093/emboj/19.11.2537 · Cited by 646

Protein kinase cascades in the regulation of cardiac hypertrophy

Dorn, G. W., & Force, T. L. (2005) · Journal of Clinical Investigation · doi:10.1172/jci24178 · Cited by 627

Fibroblast growth factor receptor tyrosine kinases: molecular analysis and signal transduction

Jaye, M., Schlessinger, J., & Dionne, C. A. (1992) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/0167-4889(92)90136-y · Cited by 617

Molecular Insights into the Klotho-Dependent, Endocrine Mode of Action of Fibroblast Growth Factor 19 Subfamily Members

Goetz, R. M., Beenken, A., Ibrahimi, O. A., Kalinina, J., Olsen, S. K., Eliseenkova, A. V., Xu, C.-F., Neubert, T. A., Zhang, F., Linhardt, R. J., et al. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.02249-06 · Cited by 550

Myosin isoenzyme redistribution in chronic heart overload

Lompré, A., Schwartz, K., d’Albis, A., Lacombe, G., Thiem, N. V., & Bernard Swynghedauw, A. (1979) · Nature · doi:10.1038/282105a0 · Cited by 523

“Stress-Responsive” Mitogen-Activated Protein Kinases (c-Jun N-Terminal Kinases and p38 Mitogen-Activated Protein Kinases) in the Myocardium

Sugden, P. H., & Clerk, A. (1998) · Circulation Research · doi:10.1161/01.res.83.4.345 · Cited by 519

MAPK signalling in cardiovascular health and disease: molecular mechanisms and therapeutic targets

Muslin, A. J. (2008) · Clinical Science · doi:10.1042/cs20070430 · Cited by 504

Calcineurin?NFAT signaling regulates the cardiac hypertrophic response in coordination with the MAPKs

Molkentin, J. D. (2004) · Cardiovascular Research · doi:10.1016/j.cardiores.2004.01.021 · Cited by 504

Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain

Mohammadi, M., Froum, S., Hamby, J. M., Schroeder, M. C., Panek, R. L., Lu, G. H., Eliseenkova, A. V., Green, D., Schlessinger, J., & Hubbard, S. R. (1998) · The EMBO Journal · doi:10.1093/emboj/17.20.5896 · Cited by 492

Regulation of MAPKs by growth factors and receptor tyrosine kinases

Katz, M., Amit, I., & Yarden, Y. (2007) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2007.01.002 · Cited by 490

Activated glycogen synthase-3β suppresses cardiac hypertrophy in vivo

Antos, C. L., McKinsey, T. A., Frey, N., Kutschke, W. J., McAnally, J., Shelton, J. M., Richardson, J. A., Hill, J. A., & Olson, E. N. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.231619298 · Cited by 476

Alterations of Left Ventricular Hypertrophy in and Survival of Patients Receiving Hemodialysis

London, G. M., Pannier, B., Guérin, A. P., Blacher, J., Marchais, S. J., Darné, B. M., Métivier, F., Adda, H., & Safar, M. E. (2001) · Journal of the American Society of Nephrology · doi:10.1681/asn.v12122759 · Cited by 465

The Associations of Fibroblast Growth Factor 23 and Uncarboxylated Matrix Gla Protein With Mortality in Coronary Artery Disease: The Heart and Soul Study

Parker, B. D., Schurgers, L. J., Brandenburg, V. M., Christenson, R. H., Vermeer, C., Ketteler, M., Shlipak, M. G., Whooley, M. A., & Ix, J. H. (2010) · Annals of Internal Medicine · doi:10.7326/0003-4819-152-10-201005180-00004 · Cited by 463

Myosin heavy chain messenger RNA and protein isoform transitions during cardiac hypertrophy. Interaction between hemodynamic and thyroid hormone-induced signals.

Izumo, S., Lompré, A., Matsuoka, R., Koren, G., Schwartz, K., Nadal‐Ginard, B., & Mahdavi, V. (1987) · Journal of Clinical Investigation · doi:10.1172/jci112908 · Cited by 448

Calcium–calcineurin signaling in the regulation of cardiac hypertrophy

Wilkins, B. J., & Molkentin, J. D. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.07.121 · Cited by 447

Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes. The potential role of the cascade in the integration of two signaling pathways leading to myocyte hypertrophy.

Bogoyevitch, M. A., Glennon, P. E., Andersson, M., Clerk, A., Lazou, A., Marshall, C. J., Parker, P. J., & Sugden, P. H. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)42228-9 · Cited by 388

Peptide growth factors can provoke "fetal" contractile protein gene expression in rat cardiac myocytes.

Parker, T. G., Packer, S. E., & Schneider, M. D. (1990) · Journal of Clinical Investigation · doi:10.1172/jci114466 · Cited by 376

Early Control of PTH and FGF23 in Normophosphatemic CKD Patients

de Oliveira, R. C., Cancela, A. L. E., Graciolli, F. G., dos Reis, L. M., Draibe, S. A., Cuppari, L., Carvalho, A. B., Jorgetti, V., Canziani, M. E. F., & Moysés, R. M. A. (2009) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.05420709 · Cited by 357

High levels of serum fibroblast growth factor (FGF)-23 are associated with increased mortality in long haemodialysis patients

Jean, G., Terrat, J.-C., Vanel, T., Hurot, J. M., Lorriaux, C., Mayor, B., & Chazot, C. (2009) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfp191 · Cited by 351

Control of Cardiac Gene Expression by Mechanical Stress

Komuro, I., & Yazaki, Y. (1993) · Annual Review of Physiology · doi:10.1146/annurev.ph.55.030193.000415 · Cited by 344

Serum intact FGF23 associate with left ventricular mass, hypertrophy and geometry in an elderly population

Mirza, M. A. I., Larsson, A. O., Melhus, H., Lind, L., & Larsson, T. E. (2009) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2009.05.013 · Cited by 341

Direct evidence for a causative role of FGF23 in the abnormal renal phosphate handling and vitamin D metabolism in rats with early-stage chronic kidney disease

Hasegawa, H., Nagano, N., Urakawa, I., Yamazaki, Y., Iijima, K., Fujita, T., Yamashita, T., Fukumoto, S., & Shimada, T. (2010) · Kidney International · doi:10.1038/ki.2010.313 · Cited by 339

Forging Forward with 10 Burning Questions on FGF23 in Kidney Disease

Wolf, M. (2010) · Journal of the American Society of Nephrology · doi:10.1681/asn.2009121293 · Cited by 310

Transcription factor GATA-4 regulates cardiac muscle-specific expression of the alpha-myosin heavy-chain gene.

Molkentin, J. D., Kalvakolanu, D. V., & Markham, B. E. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.7.4947 · Cited by 309

Use of tibial length to quantify cardiac hypertrophy: application in the aging rat

Yin, F. C. P., Spurgeon, H. A., Rakusan, K., Weisfeldt, M. L., & Lakatta, E. G. (1982) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1982.243.6.h941 · Cited by 296

Left Ventricular Hypertrophy in the Renal Patient

Middleton, R., Parfrey, P. S., & Foley, R. N. (2001) · Journal of the American Society of Nephrology · doi:10.1681/asn.v1251079 · Cited by 294

Effect of Hypophosphatemia on Myocardial Performance in Man

O'Connor, L. R., Wheeler, W. S., & Bethune, J. E. (1977) · New England Journal of Medicine · doi:10.1056/nejm197710272971702 · Cited by 292

Prognostic Impact of the Indexation of Left Ventricular Mass in Patients Undergoing Dialysis

Zoccali, C., Benedetto, F. A., Mallamaci, F., Tripepi, G. L., Giacone, G., Cataliotti, A., Seminara, G., Stancanelli, B., & Malatino, L. (2001) · Journal of the American Society of Nephrology · doi:10.1681/asn.v12122768 · Cited by 292

Differential Expression of the Fibroblast Growth Factor Receptor (FGFR) Multigene Family in Normal Human Adult Tissues

Hughes, S. (1997) · Journal of Histochemistry & Cytochemistry · doi:10.1177/002215549704500710 · Cited by 283

The Autosomal Dominant Hypophosphatemic Rickets R176Q Mutation in Fibroblast Growth Factor 23 Resists Proteolytic Cleavage and Enhances in Vivo Biological Potency

Bai, X., Miao, D., Goltzman, D., & Karaplis, A. C. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m210490200 · Cited by 274

Overexpression of Fibroblast Growth Factor 23 Suppresses Osteoblast Differentiation and Matrix Mineralization In Vitro

Wang, H., Yoshiko, Y., Yamamoto, R., Minamizaki, T., Kozai, K., Tanne, K., Aubin, J. E., & Maeda, N. (2008) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.080220 · Cited by 263

Parathyroid cell resistance to fibroblast growth factor 23 in secondary hyperparathyroidism of chronic kidney disease

Galitzer, H., Ben‐Dov, I. Z., Silver, J., & Naveh‐Many, T. (2009) · Kidney International · doi:10.1038/ki.2009.464 · Cited by 246

Circulating Fibroblast Growth Factor 23 in Patients with End-Stage Renal Disease Treated by Peritoneal Dialysis Is Intact and Biologically Active

Shimada, T., Urakawa, I., Isakova, T., Yamazaki, Y., Epstein, M., Wesseling‐Perry, K., Wolf, M. S., Salusky, I. B., & Jüppner, H. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-1603 · Cited by 230

Left Ventricular Hypertrophy in Nondiabetic Predialysis CKD

Paoletti, E., Bellino, D., Cassottana, P., Rolla, D., & Cannella, G. (2005) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2005.04.031 · Cited by 218

Analysis of the Biochemical Mechanisms for the Endocrine Actions of Fibroblast Growth Factor-23

Yu, X., Ibrahimi, O. A., Goetz, R. M., Zhang, F., Davis, S. I., Garringer, H. J., Linhardt, R. J., Ornitz, D. M., Mohammadi, M., & White, K. E. (2005) · Endocrinology · doi:10.1210/en.2005-0670 · Cited by 213

Prognostic Value of Echocardiographic Indicators of Left Ventricular Systolic Function in Asymptomatic Dialysis Patients

Zoccali, C., Benedetto, F. A., Mallamaci, F., Tripepi, G. L., Giacone, G., Cataliotti, A., Seminara, G., Stancanelli, B., & Malatino, L. (2004) · Journal of the American Society of Nephrology · doi:10.1097/01.asn.0000117977.14912.91 · Cited by 205

Biological activities of fibroblast growth factor-2 in the adult myocardium

Detillieux, K. A. (2002) · Cardiovascular Research · doi:10.1016/s0008-6363(02)00708-3 · Cited by 201

Induction of the skeletal alpha-actin gene in alpha 1-adrenoceptor-mediated hypertrophy of rat cardiac myocytes.

Bishopric, N. H., Simpson, P. C., & Ordahl, C. P. (1987) · Journal of Clinical Investigation · doi:10.1172/jci113179 · Cited by 200

The Klotho gene family as a regulator of endocrine fibroblast growth factors

Kurosu, H., & Kuro‐o, M. (2008) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2008.10.052 · Cited by 198

Fatty Acid Utilization in the Hypertrophied and Failing Heart: Molecular Regulatory Mechanisms

Barger, P. M., & Kelly, D. P. (1999) · The American Journal of the Medical Sciences · doi:10.1097/00000441-199907000-00006 · Cited by 192

Sox9 is required for precursor cell expansion and extracellular matrix organization during mouse heart valve development

Lincoln, J., Kist, R., Scherer, G., & Yutzey, K. E. (2007) · Developmental Biology · doi:10.1016/j.ydbio.2007.02.002 · Cited by 187

IMPACT OF RENAL TRANSPLANTATION ON UREMIC CARDIOMYOPATHY

Parfrey, P. S., Harnett, J. D., Foley, R. N., Kent, G. M., Murray, D. C., Barré, P. E., & Guttmann, R. D. (1995) · Transplantation · doi:10.1097/00007890-199511000-00005 · Cited by 173

Calsarcin-2 deficiency increases exercise capacity in mice through calcineurin/NFAT activation

Frey, N., Frank, D., Lippl, S., Kühn, C., Kögler, H., Barrientos, T., Rohr, C. M., Will, R. D., Müller, O. J., Weiler-Guettler, H., et al. (2008) · Journal of Clinical Investigation · doi:10.1172/jci36277 · Cited by 148

The Cytoskeleton and Related Proteins in the Human Failing Heart

Sawa Kostin, D., Hein, S., Arnon, E., Scholz, D., & Schaper, J. (2000) · Heart Failure Reviews · doi:10.1023/a:1009813621103 · Cited by 143

Control of Cardiac Growth and Function by Calcineurin Signaling

Vega, R. B., Bassel‐Duby, R., & Olson, E. N. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.r300023200 · Cited by 132

The Crystal Structure of Fibroblast Growth Factor (FGF) 19 Reveals Novel Features of the FGF Family and Offers a Structural Basis for Its Unusual Receptor Affinity,

Harmer, N. J., Pellegrini, L., Chirgadze, D., Fernández‐Recio, J., & Blundell, T. L. (2003) · Biochemistry · doi:10.1021/bi035320k · Cited by 124

The transcriptional repressor Nab1 is a specific regulator of pathological cardiac hypertrophy

Buitrago, M. A. B., Lorenz, K., Maass, A. H., Oberdorf‐Maass, S. U., Keller, U., Schmitteckert, E. M., Ivashchenko, Y., Lohse, M. J., & Engelhardt, S. H. (2005) · Nature Medicine · doi:10.1038/nm1272 · Cited by 116

IMPACT OF RENAL TRANSPLANTATION ON UREMIC CARDIOMYOPATHY

Parfrey, P. S., Harnett, J. D., Foley, R. N., Kent, G. M., Murray, D. C., Barré, P. E., & Guttmann, R. D. (1995) · Transplantation · doi:10.1097/00007890-199511150-00005 · Cited by 114

Reversible depression in myocardial performance in dogs with experimental phosphorus deficiency.

Fuller, T. J., Nichols, W., Brenner, B. J., & Peterson, J. C. (1978) · Journal of Clinical Investigation · doi:10.1172/jci109239 · Cited by 106

Comparative toxicity of allylamine and acrolein in cultured myocytes and fibroblasts from neonatal rat heart

Toraason, M. A., Luken, M. E., Breitenstein, M. J., KRUEGER, J. A., & Biagini, R. E. (1989) · Toxicology · doi:10.1016/0300-483x(89)90216-3 · Cited by 103

Protein Kinase A, Ca2+/Calmodulin-Dependent Kinase II, and Calcineurin Regulate the Intracellular Trafficking of Myopodin between the Z-Disc and the Nucleus of Cardiac Myocytes

Faul, C., Dhume, A., Schecter, A. D., & Mundel, P. H. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.00950-07 · Cited by 86

Effect of paricalcitol and cinacalcet on serum phosphate, FGF-23, and bone in rats with chronic kidney disease

Finch, J. L., Tokumoto, M., Nakamura, H. K., Yao, W., Shahnazari, M., Lane, N. E., & Slatopolsky, E. (2010) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00552.2009 · Cited by 81

Trophic Effect of Human Pericardial Fluid on Adult Cardiac Myocytes

Corda, S., Mebazaa, A., Gandolfini, M.-P., Fitting, C., Marotte, F., Peynet, J., Charlemagne, D., Cavaillon, J., Payen, D. M., Rappaport, L., et al. (1997) · Circulation Research · doi:10.1161/01.res.81.5.679 · Cited by 80

Cardiovascular Abnormalities in Patients with X-Linked Hypophosphatemia

Nehgme, R., Fahey, J. T., Smith, C. R., & Carpenter, T. O. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.8.4181 · Cited by 77

Fibroblast growth factor 2 isoforms and cardiac hypertrophy

Kardami, E. (2004) · Cardiovascular Research · doi:10.1016/j.cardiores.2004.04.024 · Cited by 71

Stimulus specific changes of energy metabolism in hypertrophied heart

Rimbaud, S., Sanchez, H., Garnier, A., Fortin, D., Bigard, X. A., Veksler, V., & Ventura‐Clapier, R. (2009) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2009.01.013 · Cited by 54

Promotion of importin α–mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3

Faul, C., Hüttelmaier, S., Oh, J. S., Hachet, V., Singer, R. H., & Mundel, P. H. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200411169 · Cited by 50

Cardioprotective effect of calcineurin inhibition in an animal model of renal disease

Marco, G. S. D., Reuter, S., Kentrup, D., Ting, L., Liu, T., Grabner, A., Jacobi, A. M., Pavenstädt, H., Baba, H. A., Tiemann, K., et al. (2010) · European Heart Journal · doi:10.1093/eurheartj/ehq436 · Cited by 39

Basic fibroblast growth factor induces myocardial hypertrophy following acute infarction in rats

Scheinowitz, M., Kotlyar, A., Zimand, S., Ohad, D. G., Leibovitz, I., Bloom, N., Goldberg, I., Nass, D., Engelberg, S., Savion, N., et al. (1998) · Experimental Physiology · doi:10.1113/expphysiol.1998.sp004140 · Cited by 28

Inactivation of myosin heavy chain genes in the mouse: Diverse and unexpected phenotypes

Allen, D. L., Harrison, B. C., & Leinwand, L. A. (2000) · Microscopy Research and Technique · doi:10.1002/1097-0029(20000915)50:6 · Cited by 26

Biologists abandon Popper at their peril

(2000) · doi:10.1002/(sici)1521-1878(200002)22:2

Should We STOP Angiotensin Converting Enzyme Inhibitors/Angiotensin Receptor Blockers in Advanced Kidney Disease?

Ahmed, A., Jorna, T., & Bhandari, S. (2016) · The Nephron journals/Nephron journals · doi:10.1159/000447068 · Cited by 11,782

The Fibroblast Growth Factor signaling pathway

Ornitz, D. M., & Itoh, N. (2015) · WIREs Developmental Biology · doi:10.1002/wdev.176 · Cited by 2,050

KDOQI US Commentary on the 2012 KDIGO Clinical Practice Guideline for the Evaluation and Management of CKD

Inker, L. A., Astor, B. C., Fox, C. H., Isakova, T., Lash, J. P., Peralta, C. A., Tamura, M. K., & Feldman, H. I. (2014) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2014.01.416 · Cited by 1,828

Cardiorenal Syndrome: Classification, Pathophysiology, Diagnosis, and Treatment Strategies: A Scientific Statement From the American Heart Association

Rangaswami, J., Bhalla, V., Blair, J. E., Chang, T. I., Costa, S. P., Lentine, K. L., Lerma, E. V., Mezue, K. N., Molitch, M. E., Müllens, W., et al. (2019) · Circulation · doi:10.1161/cir.0000000000000664 · Cited by 1,535

The Osteocyte: An Endocrine Cell … and More

Dallas, S. L., Prideaux, M., & Bonewald, L. F. (2013) · Endocrine Reviews · doi:10.1210/er.2012-1026 · Cited by 1,042

Induction of cardiac FGF23/FGFR4 expression is associated with left ventricular hypertrophy in patients with chronic kidney disease

Leifheit‐Nestler, M., Siemer, R. G., Flasbart, K., Richter, B., Kirchhoff, F., Ziegler, W. H., Klintschar, M., Becker, J. U., Erbersdobler, A., Aufricht, C., et al. (2015) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfv421 · Cited by 207

Connecting the dots on fibroblast growth factor 23 and left ventricular hypertrophy

Gutiérrez, O. M. (2016) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfv445 · Cited by 5

SaO027CARDIO-PATHOLOGICAL EFFECTS OF FGF23 IN CKD ARE MEDIATED BY FGFR4

Grabner, A., Amaral, A. P., Singh, S., Schramm, K. J., Sloan, A. J., Kentrup, D., Reuter, S., Pavenstaedt, H., Marco, G. S. D., Wolf, M., et al. (2015) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfv150.04

FGF-23, Left Ventricular Hypertrophy, and Mortality in Patients With CKD

Hidaka, N., Inoue, K., Katô, H., Hoshino, Y., Koga, M., Kinoshita, Y., Takashi, Y., Makita, N., Fukumoto, S., Nangaku, M., et al. (2023) · JACC Advances · doi:10.1016/j.jacadv.2023.100747 · Cited by 13

Fibroblast Growth Factor 23 and Left Ventricular Hypertrophy in Chronic Kidney Disease

Gutiérrez, O. M., Januzzi, J. L., Isakova, T., Laliberte, K. A., Smith, K., Collerone, G., Sarwar, A., Hoffmann, U., Coglianese, E. E., Christenson, R. H., et al. (2009) · Circulation · doi:10.1161/circulationaha.108.844506 · Cited by 843