Cellular senescence and the senescent secretory phenotype: therapeutic opportunities

Cited by (1,003)

Items 501–600 of 1,003

1. A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways Across Tissues
   2021
2. Removal of senescent cells reduces the viral load and attenuates pulmonary and systemic inflammation in SARS-CoV-2-infected, aged hamsters
   Lou Delval, Aline Hantute-Ghesquier, Valentin Sencio, Jean‐Michel Flaman, Cyril Robil, Fabiola Silva Angulo, Larissa Lipskaia, Özmen Çobanoglu, Anne‐Sophie Lacoste, Arnaud Machelart et al. · 2023 · Nature Aging
3. Ginkgetin Alleviates Inflammation and Senescence by Targeting STING
   Yadan Liu, Jialin Ye, Zisheng Fan, Xiaolong Wu, Yinghui Zhang, Ruirui Yang, Bing Jiang, Yajie Wang, Min Wu, Jingyi Zhou et al. · 2024 · Advanced Science
4. Preparing for an Aging World: Engaging Biogerontologists, Geriatricians, and the Society
   Janko Nikolich‐Žugich, Dana P. Goldman, Paul R. Cohen, Denis A. Cortese, Luigi Fontana, Brian Keith Kennedy, M. Jane Mohler, S. Jay Olshansky, Thomas T. Perls, Daniel P. Perry et al. · 2015 · The Journals of Gerontology Series A
5. Cancer driver mutations in endometriosis: Variations on the major theme of fibrogenesis
   Sun‐Wei Guo · 2018 · Reproductive Medicine and Biology
6. Articulating the Case for the Longevity Dividend
   S. Jay Olshansky · 2016 · Cold Spring Harbor Perspectives in Medicine
7. Multiparametric senescent cell phenotyping reveals targets of senolytic therapy in the aged murine skeleton
   Doolittle, Madison L., Saul, Dominik, Kaur, Japneet, Rowsey, Jennifer L., Vos, Stephanie J., Pavelko, Kevin D., Farr, Joshua N., Monroe, David G., Khosla, Sundeep · 2023 · Nature Communications
8. Multiparametric senescent cell phenotyping reveals CD24 osteolineage cells as targets of senolytic therapy in the aged murine skeleton
   Doolittle, Madison L., Saul, Dominik, Kaur, Japneet, Rowsey, Jennifer L., Vos, Stephanie J., Pavelko, Kevin D., Farr, Joshua N., Monroe, David G., Khosla, Sundeep · 2023
9. Translating the Biology of Aging into New Therapeutics for Alzheimer's Disease: Senolytics
   Markus Rießland, Miranda E. Orr · 2023 · The Journal of Prevention of Alzheimer s Disease
10. Stromal Fibroblast in Age-Related Cancer: Role in Tumorigenesis and Potential as Novel Therapeutic Target
    Abdelouahid El‐Khattouti, Mohamed Hassan, Christian R. Gómez · 2015 · Frontiers in Oncology
11. The microRNA-34a-Induced Senescence-Associated Secretory Phenotype (SASP) Favors Vascular Smooth Muscle Cells Calcification
    Estella Zuccolo, Ileana Badi, Francesco Scavello, Irene Gambuzza, Luigi Mancinelli, Federica Macrì, Calogero C. Tedesco, Fabrizio Veglia, Anna Rita Bonfigli, Fabiola Olivieri et al. · 2020 · International Journal of Molecular Sciences
12. Long-term cardiovascular complications following sepsis: is senescence the missing link?
    Hamid Merdji, Valérie B. Schini‐Kerth, Ferhat Meziani, Florence Toti · 2021 · Annals of Intensive Care
13. IFN-γ and TNF Induce Senescence and a Distinct Senescence-Associated Secretory Phenotype in Melanoma
    Lorenzo Homann, Maximilian Rentschler, Ellen Brenner, Katharina Böhm, Martin Röcken, Thomas Wieder · 2022 · Cells
14. Senescent preosteoclast secretome promotes metabolic syndrome associated osteoarthritis through cyclooxygenase 2
    Weiping Su, Guanqiao Liu, Bahram Mohajer, Jiekang Wang, Alena Shen, Weixin Zhang, Bin Liu, Ali Guermazi, Peisong Gao, Xu Cao et al. · 2022 · eLife
15. Ergothioneine promotes longevity and healthy aging in male mice
    Makoto Katsube, Takahiro Ishimoto, Yutaro Fukushima, Asuka Kagami, Tsuyoshi Shuto, Yukio Kato · 2024 · GeroScience
16. Therapy with Multipotent Mesenchymal Stromal Cells Protects Lungs from Radiation-Induced Injury and Reduces the Risk of Lung Metastasis
    Diana Klein, Alexandra Schmetter, Roze Imsak, Florian Wirsdörfer, Kristian Unger, Holger Jastrow, Martin Stuschke, Verena Jendrossek · 2015 · Antioxidants and Redox Signaling
17. Trial Watch: Radioimmunotherapy for oncological indications
    Norma Bloy, Jonathan G. Pol, Gwenola Manic, Ilio Vitale, Alexander M.M. Eggermont, Jérôme Galon, Éric Tartour, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi · 2014 · OncoImmunology
18. Inhibition of PI3K/Akt/mTOR signaling in PI3KR2-overexpressing colon cancer stem cells reduces tumor growth due to apoptosis
    Sugong Chen, Robert C. Fisher, Steven A. Signs, L. Alex Molina, Anitha Kota Shenoy, Maria-Cecilia Lopez, Henry V. Baker, John M. Koomen, Yi Chen, Haley R Gittleman et al. · 2016 · Oncotarget
19. Blackberry, raspberry and black raspberry polyphenol extracts attenuate angiotensin II-induced senescence in vascular smooth muscle cells
    Rafaela G. Feresin, Jingwen Huang, DawnKylee S Klarich, Yitong Zhao, Shirin Pourafshar, Bahram Herman Arjmandi, Gloria Salazar · 2016 · Food & Function
20. Senescence and tumor suppression
    Philip W. Hinds, Jodie R. Pietruska · 2017 · F1000Research
21. Age-Related Changes to Human Tear Composition
    Alessandra Micera, Antonio Di Zazzo, Graziana Esposito, Rosa Helena Longo, William Foulsham, Roberto Sacco, Roberto Sgrulletta, Stefano Bonini · 2018 · Investigative Ophthalmology & Visual Science
22. Ginsenoside Rg1 protects against d-galactose induced fatty liver disease in a mouse model via FOXO1 transcriptional factor
    Rongjia Qi, Rong Jiang, Hanxianzhi Xiao, Ziling Wang, Siyuan He, Lu Wang, Yaping Wang · 2020 · Life Sciences
23. How does adipose tissue contribute to inflammageing?
    Zamboni, Mauro, Nori, Nicole, Brunelli, Anna, Zoico, Elena · 2021 · Experimental Gerontology
24. LncRNA SNHG4 promotes prostate cancer cell survival and resistance to enzalutamide through a let-7a/RREB1 positive feedback loop and a ceRNA network
    Qingzhuo Dong, Hui Qiu, Chiyuan Piao, Zhengxiu Li, Xiaolu Cui · 2023 · Journal of Experimental & Clinical Cancer Research
25. Inflammation unites diverse acute and chronic diseases
    Peter Libby, Robin D. Smith, Eric J. Rubin, Marilyn K. Glassberg, Michael E. Farkouh, Robert S. Rosenson · 2024 · European Journal of Clinical Investigation
26. The relationship between telomere length and aging-related diseases
    Xuanqi Huang, Leyi Huang, Jiameng Lu, Lijuan Cheng, Du An Wu, Linmeng Li, Shuting Zhang, Xinyue Lai, Lu Xu · 2025 · Clinical and Experimental Medicine
27. Cigarette Smoke Induces Human Airway Epithelial Senescence via Growth Differentiation Factor 15 Production
    Qun Wu, Di Jiang, Jennifer L. Matsuda, Kristina Ternyak, Bicheng Zhang, Hong Wei Chu · 2016 · American Journal of Respiratory Cell and Molecular Biology
28. Toll-like receptor-4 signaling pathway in aorta aging and diseases: “its double nature”
    Carmela Rita Balistreri, Giovanni Ruvolo, Domenico Lio, Rosalinda Madonna · 2017 · Journal of Molecular and Cellular Cardiology
29. HMG-CoA Reductase Inhibition Delays DNA Repair and Promotes Senescence After Tumor Irradiation
    Elena V. Efimova, Natalia Ricco, Edwardine Labay, Helena J. Mauceri, Amy C. Flor, Aishwarya Ramamurthy, Harold G. Sutton, Ralph R. Weichselbaum, Stephen J. Kron · 2017 · Molecular Cancer Therapeutics
30. Oxidative stress, telomeres and cellular senescence: What non-drug interventions might break the link?
    Jorge D. Erusalimsky · 2020 · Free Radical Biology and Medicine
31. Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and promotes a pro-regenerative environment in osteoarthritis
    Marta Varela-Eirín, Paula Carpintero-Fernández, Agustín Sánchez‐Temprano, Adrián Varela-Vázquez, Carlos Luis Paíno, Antonio Casado‐Díaz, Alfonso Jesús Calañas Continente, Virginia Mato‐Abad, Eduardo Fonseca, Mustapha Kandouz et al. · 2020 · Aging
32. Aging Impairs Mitochondrial Function and Mitophagy and Elevates Interleukin 6 Within the Cerebral Vasculature
    Tyrrell, Daniel J., Blin, Muriel G., Song, Jianrui, Wood, Sherri C., Goldstein, Daniel R. · 2020 · Journal of the American Heart Association
33. Histone Variant H2A.J Marks Persistent DNA Damage and Triggers the Secretory Phenotype in Radiation-Induced Senescence
    Isermann, Anna, Mann, Carl, Rübe, Claudia E. · 2020 · International Journal of Molecular Sciences
34. Obesity-induced neuroinflammation and cognitive impairment in young adult versus middle-aged mice
    Rosemary E. Henn, Sarah E. Elzinga, Emily Glass, Rachel Parent, Kai Guo, Adam M. Allouch, Faye E. Mendelson, John Hayes, Ian F. Webber‐Davis, Geoffery G. Murphy et al. · 2022 · Immunity & Ageing
35. The effect of metformin on senescence of T lymphocytes
    Jia Hui Yang, Hai-Cheng Liu, Jianqing Zhang, Jianyong Zou, Xin Zhang, Wo‐Ming Chen, Yong Gu, Hai Yu Hong · 2023 · Immunity & Ageing
36. Mesenchymal stem cell-derived inflammatory fibroblasts mediate interstitial fibrosis in the aging heart
    JoAnn Trial, Mark L. Entman, Katarzyna A. Cieslik · 2015 · Journal of Molecular and Cellular Cardiology
37. Age‐associated vascular inflammation promotes monocytosis during atherogenesis
    Wei Du, Christine K. Wong, Yang Song, Hua Shen, Daniel N. Mori, Noemí Rotllán, Nathan L. Price, Anca Dana Dobrian, Hailong Meng, Steven H. Kleinstein et al. · 2016 · Aging Cell
38. Energetic interventions for healthspan and resiliency with aging
    Derek M. Huffman, Marissa J. Schafer, Nathan K. LeBrasseur · 2016 · Experimental Gerontology
39. Intracellular signalling pathways: targets to reverse immunosenescence
    Tamàs Fülöp, Jacek Maciej Witkowski, Aurélie Y. Le Page, Carl F Fortin, Graham Pawelec, Anis Larbi · 2016 · Clinical & Experimental Immunology
40. Functional Interaction between Melatonin Signaling and Noncoding RNAs
    Shih‐Chi Su, Russel Joseph Reiter, Hui‐Yi Hsiao, Wen‐Hung Chung, Shun‐Fa Yang · 2018 · Trends in Endocrinology and Metabolism
41. SIRT1 regulates osteoblast senescence through SOD2 acetylation and mitochondrial dysfunction in the progression of Osteoporosis caused by Cadmium exposure
    Dehui Zhou, Yawei Ran, Rui Yu, Zongping Liu, Di Ran, Zongping Liu · 2023 · Chemico-Biological Interactions
42. Increased transport of acetyl‐CoA into the endoplasmic reticulum causes a progeria‐like phenotype
    Yajing Peng, Samantha L. Shapiro, Varuna C. Banduseela, Inca A. Dieterich, Kyle J. Hewitt, Emery H. Bresnick, Guangyao Kong, Jing Zhang, Kathryn L. Schueler, Mark P. Keller et al. · 2018 · Aging Cell
43. G Protein-Coupled Receptor Systems and Their Role in Cellular Senescence
    Paula Santos‐Otte, Hanne Leysen, Jaana van Gastel, Jhana O. Hendrickx, Bronwen Martin, Stuart R. Maudsley · 2019 · Computational and Structural Biotechnology Journal
44. Untitled work
    2023 · 10.1016/j.celrep.2023.112593
45. As we age: Does slippage of quality control in the immune system lead to collateral damage?
    Ludmila Müller, Graham Pawelec · 2015 · Ageing Research Reviews
46. Cellular and molecular basis of the imbalance between vascular damage and repair in ageing and age-related diseases: As biomarkers and targets for new treatments
    Rosalinda Madonna, Giuseppina Novo, Carmela Rita Balistreri · 2016 · Mechanisms of Ageing and Development
47. Screening of a kinase library reveals novel pro-senescence kinases and their common NF-κB-dependent transcriptional program
    Mylène Ferrand, Olivier Kirsh, Audrey Griveau, David Vindrieux, Nadine Martin, Pierre‐Antoine Defossez, David Bernard · 2015 · Aging
48. Senescence gives insights into the morphogenetic evolution of anamniotes
    Éric Villiard, Jean-François Denis, Faranak Sadat Hashemi, Sebastian Igelmann, Gerardo Ferbeyre, Stéphane Roy · 2017 · Biology Open
49. Nutrient sensing pathways as therapeutic targets for healthy ageing
    Anna Aiello, Giulia Accardi, Giuseppina Candore, Caterina Maria Gambino, Mario G. Mirisola, Giusi Taormina, Claudia Virruso, Calogero Caruso · 2017 · Expert Opinion on Therapeutic Targets
50. Geroprotectors: A role in the treatment of frailty
    Anne‐Ulrike Trendelenburg, Ariane C. Scheuren, Paul K Potter, Ralph Müller, Ilaria Bellantuono · 2019 · Mechanisms of Ageing and Development
51. Intestinal stem cells acquire premature senescence and senescence associated secretory phenotype concurrent with persistent DNA damage after heavy ion radiation in mice
    Santosh Kumar, Shubhankar Suman, Albert J. Fornace, Kamal Datta · 2019 · Aging
52. The importance of the nitric oxide‐cGMP pathway in age‐related cardiovascular disease: Focus on phosphodiesterase‐1 and soluble guanylate cyclase
    Keivan Golshiri, Ehsan Ataei Ataabadi, Eliana Portilla-Fernández, A.H. Jan Danser, Anton J.M. Roks · 2019 · Basic & Clinical Pharmacology & Toxicology
53. Chronic Intermittent Hypoxia Triggers a Senescence-like Phenotype in Human White Preadipocytes
    Katarzyna Polonis, Christiane Becari, C. Anwar A. Chahal, Yuebo Zhang, Alina M. Allen, Todd Andrew Kellogg, Virend Kristen Somers, Prachi Singh · 2020 · Scientific Reports
54. Transient metabolic improvement in obese mice treated with navitoclax or dasatinib/quercetin
    Arantzazu Sierra‐Ramírez, José Luis López-Aceituno, Luis Filipe Costa‐Machado, Adrián Plaza, Marta Barradas, Pablo J. Fernández-Marcos · 2020 · Aging
55. Do polyunsaturated fatty acids protect against bone loss in our aging and osteoporotic population?
    Kari Martyniak, Fei Wei, Amelia Ballesteros, Teerin T. Meckmongkol, Ashley N. Calder, Timothy A. Gilbertson, Nina A. Orlovskaya, Melanie Jean Coathup · 2020 · Bone
56. Senescent Cell Depletion Through Targeting BCL-Family Proteins and Mitochondria
    Ying Fan, Jiaoqi Cheng, Huihong Zeng, Lijian Shao · 2020 · Frontiers in Physiology
57. Cellular Senescence and Periodontitis: Mechanisms and Therapeutics
    Sijia Chen, Dian Zhou, Ousheng Liu, Huan Chen, Yuehong Wang, Yueying Zhou · 2022 · Biology
58. Crosstalk between proximal tubular epithelial cells and other interstitial cells in tubulointerstitial fibrosis after renal injury
    Congcong Guo, Yuying Cui, Mingwen Jiao, Jinming Yao, Junyu Zhao, Yutian Tian, Jianjun Dong, Lin Liao · 2024 · Frontiers in Endocrinology
59. Exploring the effects of Dasatinib, Quercetin, and Fisetin on DNA methylation clocks: a longitudinal study on senolytic interventions
    Edwin Lee, Natàlia Carreras-Gallo, Leilani Lopez, Logan Turner, Aaron Lin, Tavis L. Mendez, Hannah Went, Alan Tomusiak, Eric M. Verdin, Michael J. Corley et al. · 2024 · Aging
60. ROS-Induced Gingival Fibroblast Senescence: Implications in Exacerbating Inflammatory Responses in Periodontal Disease
    Shuling Guo, Liangliang Fu, Chenghu Yin, Wenjun Shao, Quan Sun, Liangwen Chen, Ting Xia, Min Wang, Haibin Xia · 2024 · Inflammation
61. Serpine1 Knockdown Enhances MMP Activity after Flexor Tendon Injury in Mice: Implications for Adhesions Therapy
    M.A.T. Freeberg, Youssef M. Farhat, Anas Easa, Jacob G. Kallenbach, Dominic W. Malcolm, Mark R. Buckley, Danielle S. W. Benoit, Hani A. Awad · 2018 · Scientific Reports
62. Oncogene-Induced Senescence as a New Mechanism of Disease: The Paradigm of Erdheim–Chester Disease
    Cavalli, Giulio, Biavasco, Riccardo, Borgiani, Bruno, Dagna, Lorenzo · 2014 · Frontiers in Immunology
63. Age‐associated adipose tissue inflammation promotes monocyte chemotaxis and enhances atherosclerosis
    Jianrui Song, Diana M. Farris, Paola Ariza, Smriti Moorjani, Mita Varghese, Muriel G. Blin, Judy Chen, Daniel J. Tyrrell, Min Zhang, Kanakadurga Singer et al. · 2023 · Aging Cell
64. Molecular mechanisms of ageing and related diseases
    Junping Liu · 2014 · Clinical and Experimental Pharmacology and Physiology
65. Loss of Arp2/3 induces an NF-κB–dependent, nonautonomous effect on chemotactic signaling
    Congying Wu, Elizabeth M. Haynes, Sreeja B. Asokan, Jeremy M. Simon, Norman E. Sharpless, Albert S. Baldwin, Ian J. Davis, Gary L. Johnson, James E. Bear · 2013 · The Journal of Cell Biology
66. Aspirin Targets SIRT1 and AMPK to Induce Senescence of Colorectal Carcinoma Cells
    Yu Ri Jung, Eun Ju Kim, Hyeong Jwa Choi, Jung-Jin Park, Hak-Su Kim, Yoon‐Jin Lee, Myung‐Jin Park, Minyoung Lee · 2015 · Molecular Pharmacology
67. The third path of tubulointerstitial fibrosis: aberrant endothelial secretome
    Mark Lipphardt, Jong Wook Song, Kei Matsumoto, Sina Dadafarin, Hassan Dihazi, Gerhard Anton Muller, Michael S. Goligorsky · 2017 · Kidney International
68. Delivery of Sonic Hedgehog Gene Repressed Irradiation-induced Cellular Senescence in Salivary Glands by Promoting DNA Repair and Reducing Oxidative Stress
    Bo Hai, Qingguo Zhao, Michael A. Deveau, Fei Liu · 2018 · Theranostics
69. Visceral Fat
    Michael D. Jensen · 2020 · Endocrinology and Metabolism Clinics of North America
70. Role of Cellular Senescence and NOX4-Mediated Oxidative Stress in Systemic Sclerosis Pathogenesis
    Sonsoles Piera-Velázquez, Sergio A. Jiménez · 2014 · Current Rheumatology Reports
71. Loss of the Osteogenic Differentiation Potential during Senescence Is Limited to Bone Progenitor Cells and Is Dependent on p53
    Geneviève Despars, Cynthia L. Carbonneau, Pascal Bardeau, Daniel L. Coutu, Christian M. Beausejour · 2013 · PLoS ONE
72. NF-κB/Rel Transcription Factors in Pancreatic Cancer: Focusing on RelA, c-Rel, and RelB
    Derya Kabacaoğlu, Dietrich Alexander Ruess, Jiaoyu Ai, Hana Algül · 2019 · Cancers
73. Prelamin A mediates myocardial inflammation in dilated and HIV-associated cardiomyopathies
    Daniel Brayson, Andrea Frustaci, Romina Verardo, Cristina Chimenti, Matteo Antonio Russo, Robert Hayward, Sadia Ahmad, Gema Vizcay‐Barrena, Andrea Protti, Peter S. Zammit et al. · 2019 · JCI Insight
74. Bacterial genotoxins induce T cell senescence
    Sarah L. Mathiasen, Laura Gall-Mas, Ioannis S. Pateras, Sofia D. P. Theodorou, Martin R.J. Namini, Morten Hansen, Océane C. B. Martin, Chella Krishna Vadivel, Konstantinos Ntostoglou, Deborah Butter et al. · 2021 · Cell Reports
75. Mitochondria-targeted esculetin mitigates atherosclerosis in the setting of aging via the modulation of SIRT1-mediated vascular cell senescence and mitochondrial function in Apoe−/− mice
    Santosh Karnewar, Sriravali Pulipaka, Sujana Katta, Devayani Panuganti, Praveen Kumar Neeli, Rajamannar Thennati, Mahesh Kumar Jerald, Srigiridhar Kotamraju · 2022 · Atherosclerosis
76. Therapeutic Perspectives for Inflammation and Senescence in Osteoarthritis Using Mesenchymal Stem Cells, Mesenchymal Stem Cell-Derived Extracellular Vesicles and Senolytic Agents
    Michael G. Rizzo, Thomas Michael Best, Johnny Huard, Marc J. Philippon, Francis John Hornicek, Zhenfeng Duan, Anthony J. Griswold, Lee D. Kaplan, Joshua M. Hare, Dimitrios Kouroupis · 2023 · Cells
77. Immunosuppressants in cancer prevention and therapy
    Mikhail V. Blagosklonny · 2013 · OncoImmunology
78. Relationship of inflammatory profile of elderly patients serum and senescence-associated secretory phenotype with human breast cancer cells proliferation: Role of IL6/IL8 ratio
    Bertha Alicia Barajas-Gómez, Óscar Rosas‐Carrasco, Sandra Lizbeth Morales-Rosales, Gibrán Pedraza-Vázquez, Viridiana Yazmín González‐Puertos, Teresa Juárez‐Cedillo, Jorge A. García, Norma Edith López‐Díazguerrero, Pablo Damián‐Matsumura, Mina Königsberg et al. · 2016 · Cytokine
79. Impact of aging on bone, marrow and their interactions
    Corey M. Hoffman, Jimin Han, Laura Maria Calvi · 2018 · Bone
80. Mouse Models of Accelerated Cellular Senescence
    Matthew J. Yousefzadeh, Kendra I. Melos, Luise A. Angelini, Christin Elizabeth Burd, Paul D. Robbins, Laura J. Niedernhofer · 2018 · Methods in molecular biology
81. Circulating Senescent T Cells Are Linked to Systemic Inflammation and Lesion Size During Human Cutaneous Leishmaniasis
    Luciana Polaco Covre, Régia F. Martins, Oliver Devine, Emma S. Chambers, Milica Vukmanovic‐Stejic, Juliana A. Silva, Reynaldo Dietze, Rodrigo Ribeiro Rodrigues, Herbert Leonel de Matos Guedes, Aloísio Falqueto et al. · 2019 · Frontiers in Immunology
82. Old blood from heterochronic parabionts accelerates vascular aging in young mice: transcriptomic signature of pathologic smooth muscle remodeling
    Tamás Kiss, Ádám Nyúl‐Tóth, Rafał Gulej, Stefano Tarantini, Tamás Csípő, Péter Mukli, Anna Ungvari, Priya Balasubramanian, Andriy Yabluchanskiy, Zoltán Benyó et al. · 2022 · GeroScience
83. Synergism of BCL-2 family inhibitors facilitates selective elimination of senescent cells
    David Rysanek, Pavla Vašicová, Jayaprakash Narayana Kolla, David Sedlák, Ladislav Anděra, Jiří Bártek, Zdeněk Hodný · 2022 · Aging
84. Sirt6 regulates postnatal growth plate differentiation and proliferation via Ihh signaling
    Jinying Piao, Kunikazu Tsuji, Hiroki Ochi, Munetaka Iwata, Daisuke Koga, Atsushi Okawa, Sadao Morita, Shu Takeda, Yoshinori Asou · 2013 · Scientific Reports
85. Loss of Glis2/NPHP7 causes kidney epithelial cell senescence and suppresses cyst growth in the Kif3a mouse model of cystic kidney disease
    Dongmei Lu, Alysha A. Rauhauser, Binghua Li, Chongyu Ren, Kayla McEnery, Jili Zhu, Moumita Chaki, Komal Vadnagara, Sarah El-Hadi, Anton M. Jetten et al. · 2016 · Kidney International
86. Ionizing radiation reduces ADAM10 expression in brain microvascular endothelial cells undergoing stress-induced senescence
    Lucinda S. McRobb, Matthew J. McKay, Jennifer R. Gamble, Michael Grace, Vaughan Moutrie, Estevam D. Santos, Vivienne S. Lee, Zhenjun Zhao, Mark P. Molloy, Marcus Andrew Stoodley · 2017 · Aging
87. Cross-Sectional and Longitudinal Relationships Between Inflammatory Biomarkers and Frailty in Community-dwelling Older Men: The Concord Health and Ageing in Men Project
    Benjumin Hsu, Vasant Hirani, Robert Graham Cumming, Vasi Naganathan, Fiona Blyth, Fredrick Clive Wright, Louise M. Waite, Markus J. Seibel, David J. Handelsman, David George Le Couteur · 2017 · The Journals of Gerontology Series A
88. Senescent Cells in Early Vascular Ageing and Bone Disease of Chronic Kidney Disease—A Novel Target for Treatment
    Sam Hobson, Samsul Arefin, Karolina R. Kublickiene, Paul G. Shiels, Peter Stenvinkel · 2019 · Toxins
89. Potential Role of Cellular Senescence in Asthma
    Zhao-Ni Wang, Ruonan Su, Bi-Yuan Yang, Kexin Yang, Lifen Yang, Yan Yan, Zhuang‐Gui Chen · 2020 · Frontiers in Cell and Developmental Biology
90. Atorvastatin-induced senescence of hepatocellular carcinoma is mediated by downregulation of hTERT through the suppression of the IL-6/STAT3 pathway
    Sin-Ting Wang, Shi‐Wei Huang, Kuang-Ting Liu, Teng‐Yu Lee, Jeng‐Jer Shieh, Chun‐Ying Wu · 2020 · Cell Death Discovery
91. Inflammageing in the cardiovascular system: mechanisms, emerging targets, and novel therapeutic strategies
    Danlin Liu, Gavin David Richardson, Fehmi Metehan Benli, Catherine Park, João Vicente Braga de Souza, Agnieszka K. Bronowska, Ioakim Spyridopoulos · 2020 · Clinical Science
92. Cellular senescence: friend or foe to respiratory viral infections?
    William J. Kelley, Rachel L. Zemans, Daniel R. Goldstein · 2020 · European Respiratory Journal
93. Accelerated aging in perinatally HIV-infected children: clinical manifestations and pathogenetic mechanisms
    Chiappini, Elena, Bianconi, Martina, Dalzini, Annalisa, Petrara, Maria Raffaella, Galli, Luisa, Giaquinto, Carlo, De Rossi, Anita · 2018 · Aging
94. Matrix metalloproteinase 10 is linked to the risk of progression to dementia of the Alzheimer’s type
    Martino Adami, Pamela V, Orellana, Adelina, García, Pablo, Kleineidam, Luca, Alarcón-Martín, Emilio, Montrreal, Laura, Aguilera, Nuria, Espinosa, Ana, Abdelnour, Carla, Rosende-Roca, Maitee et al. · 2022 · Brain
95. Subcellular structure, heterogeneity, and plasticity of senescent cells
    Thais Cardoso Bitencourt, José Eduardo Vargas, Andrew Oliveira Silva, Lucas Rosa Fraga, Eduardo Cremonese Filippi‐Chiela · 2024 · Aging Cell
96. Senescence, NK cells, and cancer: navigating the crossroads of aging and disease
    Marina Gergues, Rafijul Bari, Sharmila Koppisetti, Anna Gosiewska, Lin Kang, ROBERT J. HARIRI · 2025 · Frontiers in Immunology
97. miRNAs in stem cell aging and age-related disease
    Soon Won Choi, Jin Young Lee, Kyung‐Sun Kang · 2017 · Mechanisms of Ageing and Development
98. Cell cycle and apoptosis regulator 2 at the interface between DNA damage response and cell physiology
    Martina Magni, Giacomo Buscemi, Laura Zannini · 2018 · Mutation Research/Reviews in Mutation Research
99. Circulating Pro-Vascular Progenitor Cell Depletion During Type 2 Diabetes
    Daniella C. Terenzi, Mohammed A. Al-Omran, Adrian Quan, Hwee Teoh, Subodh Verma, David A. Hess · 2018 · JACC Basic to Translational Science
100. Molecular mechanisms of natural compounds in cell death induction and sensitization to chemotherapeutic drugs in lung cancer
     Onsurang Wattanathamsan, Yoshihiro Hayakawa, Varisa Pongrakhananon · 2019 · Phytotherapy Research