Autophagy and neurodegeneration

Repertoires of Autophagy in the Pathogenesis of Ocular Diseases

Li, Y., Jiang, Q. L., Cao, G.-F., Yao, J., & Yan, B. (2015) · Cellular Physiology and Biochemistry · doi:10.1159/000373980 · Cited by 16,351

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

MACDONALD, M. (1993) · Cell · doi:10.1016/0092-8674(93)90585-e · Cited by 8,366

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

Kitada, T., Asakawa, S., Hattori, N., Matsumine, H., Yamamura, Y., Minoshima, S., Yokochi, M., Mizuno, Y., & Shimizu, N. (1998) · Nature · doi:10.1038/33416 · Cited by 5,227

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

Goate, A., Chartier-Harlin, M.-C., Mullan, M., Brown, J., Crawford, F., Fidani, L., Giuffra, L., Haynes, A., Irving, N., James, L., et al. (1991) · Nature · doi:10.1038/349704a0 · Cited by 4,659

α-Synuclein Locus Triplication Causes Parkinson's Disease

Singleton, A. B., Farrer, M., Johnson, J., Singleton, A., Hague, S., Kachergus, J., Hulihan, M., Peuralinna, T., Dutra, A., Nussbaum, R., et al. (2003) · Science · doi:10.1126/science.1090278 · Cited by 4,383

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

Sherrington, R., Rogaev, E. I., Liang, Y., Rogaeva, E. A., Levesque, G., Ikeda, M., Chi, H., Lin, C., Li, G., Holman, K., et al. (1995) · Nature · doi:10.1038/375754a0 · Cited by 4,051

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

Narendra, D., Tanaka, A., Suen, D.-F., & Youle, R. J. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200809125 · Cited by 4,026

mTOR: from growth signal integration to cancer, diabetes and ageing

Zoncu, R., Efeyan, A., & Sabatini, D. M. (2011) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3025 · Cited by 3,941

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

Hara, T., Nakamura, K., Matsui, M., Yamamoto, A., Nakahara, Y., Suzuki-Migishima, R., Yokoyama, M., Mishima, K., Saito, I., Okano, H., et al. (2006) · Nature · doi:10.1038/nature04724 · Cited by 3,882

The Autophagy-Related Beclin-1 Protein Requires the Coiled-Coil and BARA Domains To Form a Homodimer with Submicromolar Affinity

Ranaghan, M. J., Durney, M. A., Mesleh, M. F., McCarren, P. R., Garvie, C. W., Daniels, D. S., Carey, K. L., Skepner, A. P., Levine, B., & Perez, J. R. (2017) · Biochemistry · doi:10.1021/acs.biochem.7b00936 · Cited by 16

Liraglutide provides neuroprotection by regulating autophagy through the AMPK-FOXO3 signaling pathway in a spinal contusion injury rat model

Zhang, D., Yu, D., Mei, X., & Lv, G. (2020) · Neuroscience Letters · doi:10.1016/j.neulet.2020.134747 · Cited by 16

Involvement of Autophagy in Levodopa‐Induced Dyskinesia

Feyder, M. T., Plewnia, C., Lieberman, O. J., Spigolon, G., Piccin, A., Urbina-Treviño, L., Dehay, B., Li, Q., Nilsson, P., Altun, M., et al. (2021) · Movement Disorders · doi:10.1002/mds.28480 · Cited by 17

ATG4B Inhibitor UAMC-2526 Potentiates the Chemotherapeutic Effect of Gemcitabine in a Panc02 Mouse Model of Pancreatic Ductal Adenocarcinoma

Takhsha, F. S., Vangestel, C., Tanç, M., Bruycker, S. D., Berg, M., Pintelon, I., Stroobants, S. G., Meyer, G. R. Y. D., der Veken, P. V., & Martinet, W. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.750259 · Cited by 16

The autophagy protein Atg9 functions in glia and contributes to parkinsonian symptoms in a Drosophila model of Parkinson’s disease

Yi, S., Wang, L., Ho, M. S., & Zhang, S. (2023) · Neural Regeneration Research · doi:10.4103/1673-5374.382259 · Cited by 15

Cellular neurobiology of hyperforin

Bouron, A. (2023) · Phytotherapy Research · doi:10.1002/ptr.8063 · Cited by 15

Autophagy: a necessary evil in cancer and inflammation

Mathur, A., Ritu, R., Chandra, P., & Das, A. (2024) · 3 Biotech · doi:10.1007/s13205-023-03864-w · Cited by 16

The initiator caspase Dronc is subject of enhanced autophagy upon proteasome impairment in Drosophila

Lee, T. V., Kaya, H. E. K., Simin, R. T., Baehrecke, E. H., & Bergmann, A. (2016) · Cell Death and Differentiation · doi:10.1038/cdd.2016.40 · Cited by 15

Autophagy in Neurodegeneration: Can’t Digest It, Spit It Out!

Barthet, V. J. A., & Ryan, K. M. (2018) · Trends in Cell Biology · doi:10.1016/j.tcb.2018.01.001 · Cited by 14

Impaired proteostasis in rare neurological diseases

Osinalde, N., Duarri, A., Ramírez, J., Barrio, R., de Nanclares, G. P., & Mayor, U. (2018) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2018.10.007 · Cited by 19

Differences in the Autophagy Response to Hypoxia in the Hippocampus and Neocortex of Rats

Churilova, A. V., Зачепило, Т. Г., Baranova, K. A., & Rybnikova, E. A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23148002 · Cited by 13

Targeting the Mitochondrial Pyruvate Carrier for Neuroprotection

Tang, B. L. (2019) · Brain Sciences · doi:10.3390/brainsci9090238 · Cited by 15

Autophagy in white matter disorders of the CNS : mechanisms and therapeutic opportunities

Nutma, E., Marzin, M. C., Cillessen, S. A. G. M., & Amor, S. (2020) · The Journal of Pathology · doi:10.1002/path.5576 · Cited by 15

The impact of diabetes mellitus on the development of psychiatric and neurological disorders

Kelly, O., Sullivan, J., Carris, N., Geci, S., Martinez, A., Liashenko, V., Colvin, J., Misko, E., Vanderlaan, G., He, L., et al. (2024) · Brain Disorders · doi:10.1016/j.dscb.2024.100135 · Cited by 18

Lanthanum chloride induces autophagy in primary cultured rat cortical neurons through Akt/mTOR and AMPK/mTOR signaling pathways

Gao, X., Yu, M., Sun, W., Han, Y., Yang, J., Lu, X., Jin, C., Wu, S., & Cai, Y. (2021) · Food and Chemical Toxicology · doi:10.1016/j.fct.2021.112632 · Cited by 14

Melatonin Protects Neural Stem Cells Against Tri-Ortho-Cresyl Phosphate-Induced Autophagy

Liu, C. X., Zhou, W., Li, Z., Ren, J. T., Li, X., Li, S., Liu, Q., Song, F., Hao, A., & Wang, F. (2020) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2020.00025 · Cited by 13

Peroxisome proliferator-activated receptors (PPARs) agonists as promising neurotherapeutics

Ghannam, I. A. Y., Hassan, R. M., & Abdel‐Maksoud, M. S. (2025) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2025.108226 · Cited by 13

Epg5 links proteotoxic stress due to defective autophagic clearance and epileptogenesis in Drosophila and Vici syndrome patients

Deneubourg, C., Dafsari, H. S., Lowe, S. A., Martinez-Cotrina, A., Mazaud, D., Park, S. H., Vergani, V., Almacellas‐Barbanoj, A., Maroofian, R., Averdunk, L., et al. (2024) · Autophagy · doi:10.1080/15548627.2024.2405956 · Cited by 13

Gyp1 has a dual function as Ypt1 GAP and interaction partner of Atg8 in selective autophagy

Mitter, A. L., Schlotterhose, P., & Krick, R. (2019) · Autophagy · doi:10.1080/15548627.2019.1569929 · Cited by 12

14,15-Epoxyeicosatrienoic Acid Protect Against Glucose Deprivation and Reperfusion-Induced Cerebral Microvascular Endothelial Cells Injury by Modulating Mitochondrial Autophagy via SIRT1/FOXO3a Signaling Pathway and TSPO Protein

Qu, Y., Cao, J., Wang, D., Wang, S., Li, Y., & Zhu, Y. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.888836 · Cited by 12

Role of apoptosis and autophagy in mediating tramadol-induced neurodegeneration in the rat hippocampus

Gholami, M., Hayes, A. W., Jamaati, H., Sureda, A., & Motaghinejad, M. (2023) · Molecular Biology Reports · doi:10.1007/s11033-023-08641-9 · Cited by 12

Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic ReticulumPreprint

Kuijpers, M., Kochlamazashvili, G., Stumpf, A., Puchkov, D., Swaminathan, A., Lucht, M. T., Krause, E., Maritzen, T., Schmitz, D., & Haucke, V. (2020) · bioRxiv · doi:10.1101/2020.07.06.189522 · Cited by 167

Emerging insights into traditional Chinese medicine associated with neurodegenerative diseases: A bibliometric analysis

Luo, Y., Hu, B., Yuan, Z., Bi, H., Yu, J., & Pan, Q. (2024) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2024.118785 · Cited by 12

Perfluorooctanoic acid (PFOA) activates astrogliosis-associated neuroinflammation through ER stress-autophagy axis

Min, E., Ko, M. Y., Kim, M. J., Park, H.-J., Kim, Y., Kim, K. K., Lee, B., Hyun, S., & Ka, M. (2025) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2025.179546 · Cited by 11

Targeting autophagy in astrocytes: a potential for neurodegenerative disease intervention

Potokar, M., & Jorgačevski, J. (2025) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2025.1584767 · Cited by 14

Unveiling mysteries of aging: the potential of melatonin in preventing neurodegenerative diseases in older adults

Ünal, Ö., Akgun-Unal, N., & Baltacı, A. K. (2025) · Biogerontology · doi:10.1007/s10522-025-10254-7 · Cited by 11

Beclin 1, LC3 and P62 Expression in Equine Sarcoids

Martano, M., Altamura, G., Power, K., Liguori, P., Restucci, B., Borzacchiello, G., & Maiolino, P. (2021) · Animals · doi:10.3390/ani12010020 · Cited by 12

Euphejolkinolide A, a new ent-abietane lactone from Euphorbia peplus L. with promising biological activity in activating the autophagy-lysosomal pathway

Ran, X., Lu, Q.-Y., Li, Y.-Y., Pu, X.-X., Guo, Y., Yuan, M.-R., Guan, S.-P., Sun, M., Jiao, L., Yao, Y., et al. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e13691 · Cited by 13

Dissecting Sex‐Related Cognition between Alzheimer’s Disease and Diabetes: From Molecular Mechanisms to Potential Therapeutic Strategies

Ashraf, G. M., Ebada, M. A., Suhail, M., Ali, A., Uddin, M. S., Bilgrami, A. L., Perveen, A., Husain, A., Tarique, M., Hafeez, A., et al. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/4572471 · Cited by 11

Pathological Nuclear Hallmarks in Dentate Granule Cells of Alzheimer’s Patients: A Biphasic Regulation of Neurogenesis

Gil, L., Chi-Ahumada, É., Niño, S. A., Capdeville, G., Méndez-Torres, A. M., Guerrero, C., Poves, A. B. R., Olazabal, I. M., & Jiménez-Capdeville, M. E. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232112873 · Cited by 10

Protein aggregation and biomolecular condensation in hypoxic environments (Review)

Li, C., Hao, B., Yang, H., Wang, K., Fan, L., & Xiao, W. (2024) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2024.5357 · Cited by 10

The effects and mechanism of estrogen on rats with Parkinson's disease in different age groups.

Li, X.-Z., Sui, C., Chen, Q., Zhuang, Y., Zhang, H., & Zhou, X. (2016) · PubMed Central · Cited by 10

Biomedical importance of the ubiquitin–proteasome system in diabetes and metabolic transdifferentiation of pancreatic duct epithelial cells into β-cells

Liu, Z., Wang, P., Yin, Z., Lai, K. P., & Li, R. (2023) · Gene · doi:10.1016/j.gene.2023.147191 · Cited by 10

Involvement of mTOR pathway in neurodegeneration in NSF-related developmental and epileptic encephalopathy

Hayashi, T., Yano, N., Kora, K., Yokoyama, A., Maizuru, K., Kayaki, T., Nishikawa, K., Osawa, M., Niwa, A., Takenouchi, T., et al. (2023) · Human Molecular Genetics · doi:10.1093/hmg/ddad008 · Cited by 10

Autophagy at the synapse, an early site of dysfunction in neurodegeneration

Jasutkar, H. G., & Yamamoto, A. (2023) · Current Opinion in Physiology · doi:10.1016/j.cophys.2023.100631 · Cited by 9

epg5 knockout leads to the impairment of reproductive success and courtship behaviour in a zebrafish model of autophagy-related diseases

Fontana, C. M., Locatello, L., Sabatelli, P., Facchinello, N., Lidron, E., Maradonna, F., Carnevali, O., Rasotto, M. B., & Valle, L. D. (2021) · Biomedical Journal · doi:10.1016/j.bj.2021.04.002 · Cited by 9

Macroautophagy and normal aging of the nervous system: Lessons from animal models

Kallergi, E., & Nikoletopoulou, V. (2021) · Cell Stress · doi:10.15698/cst2021.10.257 · Cited by 10

ATase inhibition rescues age-associated proteotoxicity of the secretory pathway

Murie, M., Peng, Y., Rigby, M. J., Dieterich, I. A., Farrugia, M. A., Endresen, A., Bhattacharyya, A., & Puglielli, L. (2022) · Communications Biology · doi:10.1038/s42003-022-03118-0 · Cited by 9

Immune complexes suppressed autophagy in glomerular endothelial cells

Wang, L., & Law, H. (2018) · Cellular Immunology · doi:10.1016/j.cellimm.2018.02.013 · Cited by 9

Autophagy promotes cell and organismal survival by maintaining NAD(H) poolsPreprint

Sedlackova, L., Otten, E. G., Scialò, F., Shapira, D., Kataura, T., Carroll, B., Seranova, E., Rabanal‐Ruiz, Y., Kelly, G., Stefanatos, R. K. A., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.01.31.928424 · Cited by 9

Glial Cytokine and Metabolic Networks in Progressive Multiple Sclerosis: From Pathophysiology to Biomarkers and Therapeutic Strategies

Hohm, H. L., Schuster, R., Buciu, V. B., Serban, D.-M., Ciurescu, S., Cornea, A., Sharma, A., Nistor, D., & Kundnani, N. R. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26188817 · Cited by 9

Differential expression of CD8 defines phenotypically distinct cytotoxic T cells in cancer and multiple sclerosis

Burkard, T., Juan, M. H. S., Dreis, C., Kiprina, A., Namgaladze, D., Siebenbrodt, K., Luger, S., Foerch, C., Pfeilschifter, J., Weigert, A., et al. (2022) · Clinical and Translational Medicine · doi:10.1002/ctm2.1068 · Cited by 7

Inhibiting autophagy by miR-19a-3p/PTEN regulation protected retinal pigment epithelial cells from hyperglycemic damage

Gong, Q., Luo, D., Wang, H., Xu, X., Fan, Y., Zheng, Z. J., & Qian, T. (2023) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2023.119530 · Cited by 9

The autophagy paradox: A new hypothesis in neurodegenerative disorders

Barmaki, H., Nourazarian, A., Shademan, B., & Khaki‐Khatibi, F. (2024) · Neurochemistry International · doi:10.1016/j.neuint.2024.105827 · Cited by 9

Different Roles of Beclin1 in the Interaction Between Glia and Neurons after Exposure to Morphine and the HIV- Trans-Activator of Transcription (Tat) Protein

Lapierre, J., Karuppan, M. K. M., Pokharel, M. D., Rodriguez, M., & El‐Hage, N. (2021) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-021-10017-4 · Cited by 9

A Therapeutic Target for Inhibition of Neurodegeneration: Autophagy

Pupyshev, A. B., Короленко, Т. А., & Tikhonova, M. A. (2017) · Neuroscience and Behavioral Physiology · doi:10.1007/s11055-017-0519-7 · Cited by 8

Fat cadherins in mouse models of degenerative ataxias

Baron, O., Grieshober, D., Dias, C., & Fanto, M. (2019) · Scientific Reports · doi:10.1038/s41598-019-52684-7 · Cited by 8

The Antidepressant Drug Amitriptyline Affects Human SH-SY5Y Neuroblastoma Cell Proliferation and Modulates Autophagy

Adornetto, A., Laganà, M. L., Satriano, A., Licastro, E., Corasaniti, M. T., Bagetta, G., & Russo, R. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms251910415 · Cited by 7

Tau proteotasis in Alzheimer’s disease

Chinnathambi, S. (2024) · Advances in protein chemistry and structural biology · doi:10.1016/bs.apcsb.2024.09.003 · Cited by 7

The Effects of Yuan‐Zhi Decoction and Its Active Ingredients in Both In Vivo and In Vitro Models of Chronic Cerebral Hypoperfusion by Regulating the Levels of Aβ and Autophagy

Liu, Y., Huang, X., Chen, W., Chen, Y., Wang, N., & Wu, X. (2020) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2020/6807879 · Cited by 7

Autophagy Modulation for Organelle-Targeting Therapy

Martins, W. K., & Baptista, M. S. (2016) · InTech eBooks · doi:10.5772/63976 · Cited by 7

Role of Cellular Senescence in Parkinson’s Disease: Potential for Disease-Modification Through Senotherapy

Rademacher, D. J., Exline, J. E., & Foecking, E. M. (2025) · Biomedicines · doi:10.3390/biomedicines13061400 · Cited by 8

Schwann Cell‐Specific Ablation of Beclin 1 Impairs Myelination and Leads to Motor and Sensory Neuropathy in Mice

Gambarotto, L., Russo, L., Bresolin, S., Persano, L., D’Amore, R., Ronchi, G., Zen, F. D., Muratori, L., Cani, A., Negro, S., et al. (2024) · Advanced Science · doi:10.1002/advs.202308965 · Cited by 6

Analysis of meta-transcriptomics and identification of genes linked to bioactive peptides and vitamins in Indonesian tempe

Tamang, J. P., Das, S., Lama, S., Utama, G. L., Safitri, R., Balia, R. L., & Thapa, N. (2025) · Food Research International · doi:10.1016/j.foodres.2025.115757 · Cited by 6

Akebia Saponin D prevents axonal loss against TNF-induced optic nerve damage with autophagy modulation

Sase, K., Tsukahara, C., Fujita, N., Arizono, I., Takagi, H., & Kitaoka, Y. (2020) · Molecular Biology Reports · doi:10.1007/s11033-020-06008-y · Cited by 6

Inhibition of p38 ameliorates axonal loss with modulation of autophagy in TNF-induced optic nerve damage

Sase, K., Tsukahara, C., Fujita, N., Arizono, I., Otsubo, M., & Kitaoka, Y. (2023) · International Ophthalmology · doi:10.1007/s10792-023-02706-1 · Cited by 6

Preventive Effects of Crocin, a Key Carotenoid Component in Saffron, Against Nicotine-Triggered Neurodegeneration in Rat Hippocampus: Possible Role of Autophagy and Apoptosis

Gholami, M., Klionsky, D. J., & Motaghinejad, M. (2024) · International Journal of Preventive Medicine · doi:10.4103/ijpvm.ijpvm_41_23 · Cited by 6

Nutrient Starvation Decreases Cx43 Levels and Limits Intercellular Communication in Primary Bovine Corneal Endothelial Cells

D’hondt, C., Iyyathurai, J., Welkenhuyzen, K., Himpens, B., Leybaert, L., & Bultynck, G. (2016) · The Journal of Membrane Biology · doi:10.1007/s00232-016-9874-5 · Cited by 6

Effects of caloric restriction on retinal aging and neurodegeneration

Adornetto, A., Morrone, L. A., Satriano, A., Laganà, M. L., Licastro, E., Nucci, C., Corasaniti, M. T., Tonin, P., Bagetta, G., & Russo, R. (2020) · Progress in brain research · doi:10.1016/bs.pbr.2020.07.005 · Cited by 6

Mutation of a Ubiquitin Carboxy Terminal Hydrolase L1 Lipid Binding Site Alleviates Cell Death, Axonal Injury, and Behavioral Deficits After Traumatic Brain Injury in Mice

Mi, Z., Liu, H., Rose, M. E., Ma, J., Reay, D. P., Ma, X., Henchir, J. J., Dixon, C. E., & Graham, S. H. (2021) · Neuroscience · doi:10.1016/j.neuroscience.2021.09.001 · Cited by 5

Detection of autophagy in Hirschsprung’s disease

Huang, Q., Ge, X., Li, P., Duan, Y., Guo, Z., Zheng, B., Wu, X., Guo, X., & Gao, Y. (2015) · Neuroreport · doi:10.1097/wnr.0000000000000465 · Cited by 5

Neuronal vacuolation and spinocerebellar degeneration associated with altered neurotransmission

Giannakopoulou, A. (2017) · Folia Neuropathologica · doi:10.5114/fn.2017.68580 · Cited by 5

The many connections of UFMylation with Alzheimer’s disease: a comprehensive review

Yan, T., Clarkson, B. D. S., Lou, Z., Springer, W., & Fiesel, F. C. (2025) · Molecular Neurodegeneration · doi:10.1186/s13024-025-00855-8 · Cited by 4

Swimming and L-arginine loaded chitosan nanoparticles ameliorates aging‐induced neuron atrophy, autophagy marker LC3, GABA and BDNF-TrkB pathway in the spinal cord of rats

Zargani, M., Ramírez‐Campillo, R., & Arabzadeh, E. (2023) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-023-02795-y · Cited by 4

Induction of proteasomal activity in mammalian cells by lifespan-extending tRNA synthetase inhibitors

Mariner, B. L., Rodriguez, A. S., Heath, O. C., & McCormick, M. A. (2023) · GeroScience · doi:10.1007/s11357-023-00938-8 · Cited by 4

p62/sequestosome-1 as a severity-reflecting plasma biomarker in Charcot–Marie–Tooth disease type 1A

Yoon, B., Kim, Y. H., Nam, S. H., Lee, H., Oh, S., Kim, N., Kim, K., Jo, Y. R., Kim, J. K., Choi, B., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-61794-w · Cited by 5

Wide Applications of Chloroquine Other Than Antimalarial

Alani, B. G., Alwash, A. H., & Ibrahim, I. T. (2020) · Pharmacology & Pharmacy · doi:10.4236/pp.2020.1110022 · Cited by 4

Effect of Sodium Valproate on the Conformational Stability of the Visual G Protein-Coupled Receptor Rhodopsin

Razzaghi, N., Fernandez-Gonzalez, P., Mas‐Sanchez, A., Vila-Julià, G., Pérez, J. J., & Garriga, P. (2021) · Molecules · doi:10.3390/molecules26103032 · Cited by 6

Involvement of Beclin‑1 in axonal protection by short‑term hyperglycemia against TNF‑induced optic nerve damage

Sase, K., Kitaoka, Y., Tsukahara, C., & Takagi, H. (2018) · Molecular Medicine Reports · doi:10.3892/mmr.2018.9568 · Cited by 7

SQSTM1/p62 drives radiosensitivity in cervical cancer via autophagy-independent mechanisms

Yoshida, M., Nunomura, H., Furuta, A., Yamada, K., Yasuda, I., Takemura, K., Tsuda, S., Yamaki‐Ushijima, A., Shima, T., Ogawa, R., et al. (2025) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2025.104633 · Cited by 3

Enhanced Retinal Ganglion Cell Survival via Autophagy Activation in a Novel Retinal Ischemia/Reperfusion Rat Model

Lee, S. H., Han, J. W., Yoon, S.-A., Chang, H. S., & Park, T. K. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27021031 · Cited by 3

New Atg9 Phosphorylation Sites Regulate Autophagic Trafficking in Glia

Wang, L., Yi, S., Zhang, S., Tsai, Y.-T., Cheng, Y.-H., Lin, Y.-T., Lin, C.-C., Lee, Y., Wang, H., & Ho, M. S. (2025) · ASN NEURO · doi:10.1080/17590914.2024.2443442 · Cited by 3

A ß-Secretase Modulator Decreases Tau Pathology and Preserves Short-Term Memory in a Mouse Model of Neurofibrillary Degeneration

Tautou, M., Eddarkaoui, S., Descamps, F., Larchanché, P.-E., Bakali, J. E., Goveas, L. M., Dumoulin, M., Lamarre, C., Blum, D. L., Buée, L., et al. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.679335 · Cited by 5

ECSIT prevents Alzheimer’s disease pathology by regulating neuronal mitochondrial ROS and mitophagyPreprint

Lepelley, A., Vaughn, L. S., Staniszewski, A., Zhang, H., Du, F., Koppensteiner, P., Tomljanovic, Z., Carneiro, F. R. G., Teich, A. F., Ninan, I., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.01.09.900407 · Cited by 3

c-Myc: Central regulator of autophagy and senescence in cancer

Ji, S., Sun, T., Zhang, Q., Wu, M., Cao, Y., Gao, R., Wang, L., Nicot, C., & Sethi, G. (2026) · Cancer Letters · doi:10.1016/j.canlet.2026.218315 · Cited by 2

Novel mutations and molecular pathways identified in patients with brain iron accumulation disorders

Si, L., Wang, Z., Li, X., Yang, S., Yao, T., Xu, E., Wang, X., & Wang, C. (2023) · Neurogenetics · doi:10.1007/s10048-023-00725-9 · Cited by 2

Acetyl-CoA and acetylation in biology and disease

Puglielli, L., Rigby, M. J., & Fernandez-Fuente, G. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-95582-9.00009-7 · Cited by 2

Spatial selectivity of ATase inhibition in mouse models of Charcot–Marie–Tooth disease

Fernandez-Fuente, G., Farrugia, M. A., Peng, Y., Schneider, A. J., Svaren, J. P., & Puglielli, L. (2024) · Brain Communications · doi:10.1093/braincomms/fcae232 · Cited by 2

Autophagy on the road to longevity and aging

Manifava, M., & Ktistakis, N. T. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-822003-0.00002-4 · Cited by 2

I nnate immunity regulates α‐synuclein clearance

Sawamura, M., Uemura, N., & Takahashi, R. (2016) · Movement Disorders · doi:10.1002/mds.26571 · Cited by 2

A Novel Human TBCK- Neuronal Cell Model Results in Severe Neurodegeneration and Partial Rescue with Mitochondrial Fission InhibitionPreprint

Angireddy, R., Karisetty, B. C., Katsura, K. A., Diaz‐Rosado, A., Murali, S., Smith, S. M., Ohl, L., Clark, K., Kossenkov, A. V., & Bhoj, E. J. K. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.30.621078 · Cited by 2

DAPL1 deficiency impairs autophagy in retinal pigment epithelium to drive age-dependent retinal pathologies

Chen, H., Tan, Q., Hu, Y., Liu, L., Liang, X., & Hou, L. (2026) · Journal of the Formosan Medical Association · doi:10.1016/j.jfma.2026.05.038 · Cited by 1

Chemical and Molecular Strategies in Restoring Autophagic Flux in TDP-43 Proteinopathy

Jamerlan, A., & Hulme, J. (2026) · Molecules · doi:10.3390/molecules31060924 · Cited by 1

Autophagy–Actin Crosstalk: Implications for Cellular Homeostasis and Disease

Fierti, A. O., Rozsa, R. G., Potu, A., Tajammal, A., & Li, H. (2026) · Cells · doi:10.3390/cells15080665 · Cited by 1

Role of ESCRT pathway and autophagy in neurodegenerative diseases

Dongre, S., Soni, N., & Bissa, B. (2026) · International review of neurobiology · doi:10.1016/bs.irn.2026.05.022 · Cited by 1

Emerging New Pathways in Malignant Neoplasms and Neurodegenerative Disorders: Perspectives for Therapeutics

Wrasidlo, W., & Masliah, E. (2026) · Cells · doi:10.3390/cells15131177 · Cited by 1

Brain Aging in HIV-1 Infection

Santerre, M., & Sawaya, B. E. (2018) · IntechOpen eBooks · doi:10.5772/intechopen.77029 · Cited by 1

Regulation of autophagy by TDP-43

Tomar, A. K., & Yadav, S. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-820066-7.00005-9 · Cited by 1

Neuroprotective effect of Vesatolimod in an experimental autoimmune encephalomyelitis mice model

Jiang, X., Song, Y., Fang, J., Yang, X., Mu, S., & Zhang, J. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.109717 · Cited by 1

Roles of endoplasmic reticulum stress and activating transcription factors in Alzheimer’s disease and Parkinson’s disease

Cheng, C.-F., Cheng, E., & Ku, H.-C. (2024) · Tzu-Chi Medical Journal · doi:10.4103/tcmj.tcmj_51_24 · Cited by 1

Combination treatment with rapamycin and glucocorticoid protects the death of mesostriatal dopaminergic neurons in animal model of Parkinson's disease

Lee, K., Kim, H. J., Kim, J. E., Elina, K. C., Kim, S., Park, Y. S., & Kim, H. K. (2025) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2025.173966 · Cited by 1

Mechanistic Target of Rapamycin

McKee-Muir, O. C., & Russell, R. C. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-812146-7.00009-3 · Cited by 2

Glymphatic Efficiency is a Critical Factor for Using Abnormal Tau in Peripheral Tissues as Biomarker for Alzheimer’s Disease

Lou, Y. (2018) · Biomarkers and Applications · doi:10.29011/2576-9588.100030 · Cited by 1

Epg5 links proteotoxic stress due to defective autophagic clearance and epileptogenesis in Drosophila and Vici Syndrome patientsPreprint

Deneubourg, C., Dafsari, H. S., Lowe, S. A., Martinez-Cotrina, A., Mazaud, D., Park, S. H., Vergani, V., Maroofian, R., Averdunk, L., Karimiani, E. G., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.04.23.590762 · Cited by 1

Tumor acidosis in malignant progression and therapy

Pellegrini, P. (2016) · Figshare

Physiological Role of Autophagy and Implications in Disease

Karanasios, E., & Ktistakis, N. T. (2016) · Springer eBooks · doi:10.1007/978-3-319-33145-4_5

Is Selective Autophagy Distinct from Starvation-Induced Autophagy?

Guillebaud, G., & Germain, M. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802937-4.00005-3

Autophagy and Cancer Chemotherapy: Inhibition or Enhancement?

Santiago‐O’Farrill, J. M., Lü, Z., & Bast, R. C. (2016) · Single Cell Biology · doi:10.4172/2168-9431.1000145

Autophagy-linked FYVE protein mediates the turnover of mutant huntingtin and modifies pathogenesis in mouse models of Huntington’s disease

Fox, L. M. (2016) · doi:10.7916/d83b60cm

Autophagy inMycobacterium abscessusInfection

Subhadra, B., & Choi, C. H. (2017) · Journal of Bacteriology and Virology · doi:10.4167/jbv.2017.47.3.122

Autophagy, a guardian against neurodegeneration

Garcı́a-Arencibia, M., Hochfeld, W. E., Toh, P. P. C., & Rubinsztein, D. C. (2010) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2010.02.008 · Cited by 159

Autophagy Induction as a Therapeutic Strategy for Neurodegenerative Diseases

Djajadikerta, A., Keshri, S., Tanasa, M. P., Prestil, R., Ryan, L., & Rubinsztein, D. C. (2019) · Journal of Molecular Biology · doi:10.1016/j.jmb.2019.12.035 · Cited by 244

Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities

Menzies, F. M., Fleming, A., Caricasole, A., Bento, C. F., Andrews, S. P., Ashkenazi, A., Füllgrabe, J., Jackson, A., Jimenez Sanchez, M., Karabiyik, C., et al. (2017) · Neuron · doi:10.1016/j.neuron.2017.01.022 · Cited by 1,134

Autophagy in Neurodegenerative Diseases: From Mechanism to Therapeutic Approach

Nah, J., Yuan, J., & Jung, Y. (2015) · Molecules and Cells · doi:10.14348/molcells.2015.0034 · Cited by 234

When the Good Turns Bad

Nassif, M., Medinas, D. B., Castillo, K., Gherardelli, C., & Hetz, C. A. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-801033-4.00017-5