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PKM2 Activator TEPP-46 Attenuates Thoracic Aortic Aneurysm and Dissection by Inhibiting NLRP3 Inflammasome-Mediated IL-1β Secretion

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UCP2-induced hypoxia promotes lipid accumulation and tubulointerstitial fibrosis during ischemic kidney injury

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Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation

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Network Pharmacology-Based Dissection of the Anti-diabetic Mechanism of Lobelia chinensis

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UCP2 as a Cancer Target through Energy Metabolism and Oxidative Stress Control

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Fatty acid metabolism in macrophages: a target in cardio-metabolic diseases

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Immunometabolism: A new target for improving cancer immunotherapy

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Comprehensive Examination of the Mouse Lung Metabolome Following Mycobacterium tuberculosis Infection Using a Multiplatform Mass Spectrometry Approach

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Complement as a Major Inducer of Harmful Events in Infectious Sepsis

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Uncoupling proteins as a therapeutic target for the development of new era drugs against neurodegenerative disorder

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Perivascular adipose tissue dysfunction aggravates adventitial remodeling in obese mini pigs via NLRP3 inflammasome/IL-1 signaling pathway

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Host-Directed Therapy in Tuberculosis: Targeting Host Metabolism

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RIPK3 Activates MLKL-Mediated Necroptosis and Inflammasome Signaling During Streptococcus Infection

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Loss of epitranscriptomic control of selenocysteine utilization engages senescence and mitochondrial reprogramming

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ATP-citrate lyase controls endothelial gluco-lipogenic metabolism and vascular inflammation in sepsis-associated organ injury

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The Role of Exogenous Hydrogen Sulfide in Free Fatty Acids Induced Inflammation in Macrophages

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The mitochondrial respiratory chain: A metabolic rheostat of innate immune cell-mediated antibacterial responses

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Role of succinic acid in the regulation of sepsis

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A Lipid Perspective on Regulated Pyroptosis

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Glia Maturation Factor and Mitochondrial Uncoupling Proteins 2 and 4 Expression in the Temporal Cortex of Alzheimer’s Disease Brain

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Acetyl-CoA synthetase 2 induces pyroptosis and inflammation of renal epithelial tubular cells in sepsis-induced acute kidney injury by upregulating the KLF5/NF-κB pathway

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Melatonin decreases M1 polarization via attenuating mitochondrial oxidative damage depending on UCP2 pathway in prorenin-treated microglia

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NLRP3 Inflammasome Blockade Reduces Cocaine-Induced Microglial Activation and Neuroinflammation

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Hydrogen Sulfide Plays an Important Role by Influencing NLRP3 inflammasome

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Pin1 Promotes NLRP3 Inflammasome Activation by Phosphorylation of p38 MAPK Pathway in Septic Shock

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Metabolic adaptations of cells at the vascular-immune interface during atherosclerosis

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Quaking Deficiency Amplifies Inflammation in Experimental Endotoxemia via the Aryl Hydrocarbon Receptor/Signal Transducer and Activator of Transcription 1–NF-κB Pathway

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Limitation of TCA Cycle Intermediates Represents an Oxygen-Independent Nutritional Antibacterial Effector Mechanism of Macrophages

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Dichloroacetate improves systemic energy balance and feeding behavior during sepsis

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Nutritional metabolomics in critical illness

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Compound K inhibits priming and mitochondria-associated activating signals of NLRP3 inflammasome in renal tubulointerstitial lesions

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The Basally Expressed p53-Mediated Homeostatic Function

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Interleukin-1 in Coronary Artery Disease

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Theaflavin mitigates acute gouty peritonitis and septic organ injury in mice by suppressing NLRP3 inflammasome assembly

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Upregulation of microRNA-335-5p reduces inflammatory responses by inhibiting FASN through the activation of AMPK/ULK1 signaling pathway in a septic mouse model

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DROSHA-Dependent AIM2 Inflammasome Activation Contributes to Lung Inflammation during Idiopathic Pulmonary Fibrosis

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The crosstalk between NLRP3 inflammasome and gut microbiome in atherosclerosis

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Inflammasome Inhibition: Putting Out the Fire

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Candida tropicalis induces NLRP3 inflammasome activation via glycogen metabolism-dependent glycolysis and JAK-STAT1 signaling pathway in myeloid-derived suppressor cells to promote colorectal carcinogenesis

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Role of UCP2 in the protective effects of PPARβ/δ activation on lipopolysaccharide-induced endothelial dysfunction

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Platelet Inhibition Prevents NLRP3 Inflammasome Activation and Sepsis-Induced Kidney Injury

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Investigation of He’s Yang Chao recipe against oxidative stress-related mitophagy and pyroptosis to improve ovarian function

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Metabolic Alterations Contribute to Enhanced Inflammatory Cytokine Production in Irgm1-deficient Macrophages

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Risperidone Exacerbates Glucose Intolerance, Nonalcoholic Fatty Liver Disease, and Renal Impairment in Obese Mice

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Inflammasome Activation and Pyroptosis via a Lipid-regulated SIRT1-p53-ASC Axis in Macrophages From Male Mice and Humans

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Palmitoylation of gasdermin D directs its membrane translocation and pore formation in pyroptosisPreprint

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Role of Damage-Associated Molecular Patterns (DAMPS) in the Postoperative Period after Colorectal Surgery

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Expressions and Regulatory Effects of P38/ERK/JNK Mapks in the Adipogenic Trans-Differentiation of C2C12 Myoblasts

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NLRP3 Inflammasome Modulates Post-Burn Lipolysis and Hepatic Fat Infiltration via Fatty Acid Synthase

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Activation of UCP2 by anethole trithione suppresses neuroinflammation after intracerebral hemorrhage

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Uncoupling protein 2 protects mice from aging

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Sensing soluble uric acid by Naip1-Nlrp3 platform

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Reprogramming Macrophage Metabolism and its Effect on NLRP3 Inflammasome Activation in Sepsis

Luo, R., Li, X., & Wang, D. (2022) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2022.917818 · Cited by 27

Uncoupling Protein 2 Increases Susceptibility to Lipopolysaccharide-Induced Acute Lung Injury in Mice

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Recent insight into the correlation of SREBP-mediated lipid metabolism and innate immune response

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Characterization of serum cytokines and circulating microRNAs that are predicted to regulate inflammasome genes in cutaneous leishmaniasis patients

Mendonça, L. S. O., Santos, J. M., Kaneto, C. M., de Carvalho, L. D., dos Santos, J. L., Augusto, D. G., Carvalho, S. M. S., Soares-Martins, J. A. P., & Silva-Jardim, I. (2020) · Experimental Parasitology · doi:10.1016/j.exppara.2020.107846 · Cited by 26

The involvement of the mitochondrial membrane in drug delivery

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Different dynamics of NLRP3 inflammasome-mediated IL-1β production in GM-CSF– and M-CSF–differentiated human macrophages

Budai, M. M., Tőzsér, J., & Benkő, S. (2017) · Journal of Leukocyte Biology · doi:10.1189/jlb.3a0716-300rr · Cited by 25

Obesity and dysregulated central and peripheral macrophage–neuron cross‐talk

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Granisetron protects polymicrobial sepsis-induced acute lung injury in mice

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Metabolic reprogramming of the inflammatory response in the nervous system: the crossover between inflammation and metabolism

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NLRP3 Inflammasome in Inflammation and Metabolism: Identifying Novel Roles in Postburn Adipose Dysfunction

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Lipid Metabolism: An Emerging Player in Sjögren’s Syndrome

Chang, K., Luo, P., Guo, Z., Yang, L., Pu, J., Han, F., Cai, F., Tang, J., & Wang, X. (2025) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-025-09023-8 · Cited by 24

4-1BBL Regulates the Polarization of Macrophages, and Inhibition of 4-1BBL Signaling Alleviates Imiquimod-Induced Psoriasis

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Fa(c)t checking: How fatty acids shape metabolism and function of macrophages and dendritic cells

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Exploring the Interplay between Fatty Acids, Inflammation, and Type 2 Diabetes

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MicroRNA-132 Negatively Regulates Palmitate-Induced NLRP3 Inflammasome Activation through FOXO3 Down-Regulation in THP-1 Cells

Byeon, H.-E., Jeon, J. Y., Kim, H. S., Kim, D. J., Lee, K. W., KANG, Y. Y., & Han, S. J. (2017) · Nutrients · doi:10.3390/nu9121370 · Cited by 22

Nervonic acid triggered ovarian inflammation by inducing mitochondrial oxidative stress to activate NLRP3/ IL-1β pathway

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The role of uncoupling protein 2 in macrophages and its impact on obesity-induced adipose tissue inflammation and insulin resistance

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Interferon Stimulated Gene Expression Is a Biomarker for Primary Mitochondrial Disease

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The role of redox signaling in mitochondria and endoplasmic reticulum regulation in kidney diseases

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UCP2 silencing restrains leukemia cell proliferation through glutamine metabolic remodeling

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Emerging nanomaterials targeting macrophage adapted to abnormal metabolism in cancer and atherosclerosis therapy (Review)

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We Know More Than We Can Tell About Diabetes and Vascular Disease: The 2016 Edwin Bierman Award Lecture

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Genetic variation in satiety signaling and hypothalamic inflammation: merging fields for the study of obesity

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The platelet pannexin 1-IL-1β axis orchestrates pancreatic ductal adenocarcinoma invasion and metastasis

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UCP2, IL18, and miR-133a-3p are dysregulated in subcutaneous adipose tissue of patients with obesity

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Plasma Metabolic Profiling of Pediatric Sepsis in a Chinese Cohort

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Caffeine Citrate Protects Against Sepsis-Associated Encephalopathy and Inhibits the UCP2/NLRP3 Axis in Astrocytes

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Progressive Host-Directed Strategies to Potentiate BCG Vaccination Against Tuberculosis

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Autophagy Mediates Escherichia Coli-Induced Cellular Inflammatory Injury by Regulating Calcium Mobilization, Mitochondrial Dysfunction, and Endoplasmic Reticulum Stress

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Nitric oxide as a regulator of B. anthracis pathogenicity

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Inhibition of fatty acid synthase protects obese mice from acute lung injury via ameliorating lung endothelial dysfunction

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miR-155 down-regulation protects the heart from hypoxic damage by activating fructose metabolism in cardiac fibroblasts

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Succinate Activates Uncoupling Protein 2 to Suppress Neuroinflammation and Confer Protection Following Intracerebral Hemorrhage

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The HO-1 Signal Prevents HMGB1-Mediated Activation of NLRP3 Inflammasomes in Lipopolysaccharide-Induced Acute Lung Injury In Vitro

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Immuno-onco-metabolism and Therapeutic Resistance

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Galangin Targets HSP90β to Alleviate Ulcerative Colitis by Controlling Fatty Acid Synthesis and Subsequent NLRP3 Inflammasome Activation

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UCP2 deficiency impairs podocyte autophagy in diabetic nephropathy

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Uncoupling protein-2 regulates M1 macrophage infiltration of gingiva with periodontitis

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Differential regulation of the immune system in a brain-liver-fats organ network during short-term fasting

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Extracellular vesicles derived from head and neck squamous cells carcinoma inhibit NLRP3 inflammasomes

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Pathways Related to NLRP3 Inflammasome Activation Induced by Gold Nanorods

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Just keep breathing: How mitochondrial metabolism influences sepsis outcome

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NLRP3 Inflammasome Deficiency Protects Against Microbial Sepsis Via Increased Lipoxin B4 Synthesis

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Fatty acid synthesis promotes inflammasome activation through NLRP3 palmitoylation

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