c-Met–mediated endothelial plasticity drives aberrant vascularization and chemoresistance in glioblastoma

Hallmarks of Cancer: The Next Generation

Hanahan, D., & Weinberg, R. A. (2011) · Cell · doi:10.1016/j.cell.2011.02.013 · Cited by 66,590 · see citing works

Radiotherapy Plus Concomitant and Adjuvant Temozolomide for Glioblastoma

Stupp, R., Mason, W. P., van den Bent, M. J., Weller, M., Fisher, B., Taphoorn, M. J. B., Belanger, K., Brandes, A. A., Marosi, C., Bogdahn, U., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa043330 · Cited by 21,807 · see citing works

The basics of epithelial-mesenchymal transition

Kalluri, R., & Weinberg, R. A. (2009) · Journal of Clinical Investigation · doi:10.1172/jci39104 · Cited by 10,196 · see citing works

Molecular mechanisms of epithelial–mesenchymal transition

Lamouille, S., Xu, J., & Derynck, R. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3758 · Cited by 8,091 · see citing works

Epithelial–mesenchymal transitions in tumour progression

Thiery, J. P. (2002) · Nature reviews. Cancer · doi:10.1038/nrc822 · Cited by 6,632 · see citing works

A Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma

Gilbert, M. R., Dignam, J. J., Armstrong, T. S., Wefel, J. S., Blumenthal, D. T., Vogelbaum, M. A., Colman, H., Chakravarti, A., Pugh, S., Won, M., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1308573 · Cited by 2,834 · see citing works

Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

Zeisberg, E. M., Tarnavski, O., Zeisberg, M., Dorfman, A. L., McMullen, J. R., Gustafsson, E., Chandraker, A. K., Yuan, X., Pu, W. T., Roberts, A. B., et al. (2007) · Nature Medicine · doi:10.1038/nm1613 · Cited by 2,224 · see citing works

Genes Expressed in Human Tumor Endothelium

Croix, B. S., Rago, C., Velculescu, V. E., Traverso, G., Romans, K. E., Montgomery, E. A., Lal, A., Riggins, G. J., Christoph Lengauer, C., Vogelstein, B., et al. (2000) · Science · doi:10.1126/science.289.5482.1197 · Cited by 1,845 · see citing works

AZD2171, a Pan-VEGF Receptor Tyrosine Kinase Inhibitor, Normalizes Tumor Vasculature and Alleviates Edema in Glioblastoma Patients

Batchelor, T. T., Sorensen, A. G., di Tomaso, E., Zhang, W.-T., Duda, D. G., Cohen, K. S., Kozak, K. R., Cahill, D. P., Chen, P.-J., Zhu, M., et al. (2007) · Cancer Cell · doi:10.1016/j.ccr.2006.11.021 · Cited by 1,769 · see citing works

Tumor angiogenesis: molecular pathways and therapeutic targets

Weis, S. M., & Cheresh, D. A. (2011) · Nature Medicine · doi:10.1038/nm.2537 · Cited by 1,739 · see citing works

Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases

Carmeliet, P., & Jain, R. K. (2011) · Nature Reviews Drug Discovery · doi:10.1038/nrd3455 · Cited by 1,678 · see citing works

Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells

Ricci‐Vitiani, L., D, R. P. M., Biffoni, M., Todaro, M., Invernici, G., Cenci, T., Maira, G., Parati, E. A., Stassi, G., Larocca, L. M., et al. (2010) · Nature · doi:10.1038/nature09557 · Cited by 1,380 · see citing works

Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth.

Bussolino, F., Di Renzo, M. F., Ziche, M., Bocchietto, E., Olivero, M., Naldini, L., Gaudino, G., Tamagnone, L., Coffer, A., & Comoglio, P. M. (1992) · The Journal of cell biology · doi:10.1083/jcb.119.3.629 · Cited by 1,337 · see citing works

Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors

De Palma, M., Venneri, M. A., Galli, R., Sergi, L. S., Politi, L. S., Sampaolesi, M., & Naldini, L. (2005) · Cancer Cell · doi:10.1016/j.ccr.2005.08.002 · Cited by 1,311 · see citing works

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

Wang, Y., Nakayama, M., Pitulescu, M. E., Schmidt, T., Bochenek, M. L., Sakakibara, A., Adams, S., Davy, A., Deutsch, U., Lüthi, U., et al. (2010) · Nature · doi:10.1038/nature09002 · Cited by 1,276 · see citing works

Glioblastoma stem-like cells give rise to tumour endothelium

Wang, R., Chadalavada, K., Wilshire, J. A., Kowalik, U., Hovinga, K. E., Geber, A. B., Fligelman, B., Leversha, M. A., Brennan, C. W., & Tabar, V. S. (2010) · Nature · doi:10.1038/nature09624 · Cited by 1,204 · see citing works

Haematopoietic stem cells derive directly from aortic endothelium during development

Bertrand, J. Y., Chi, N. C., Santoso, B., Teng, S., Stainier, D. Y. R., & Traver, D. J. (2010) · Nature · doi:10.1038/nature08738 · Cited by 1,053 · see citing works

Discovery of Endothelial to Mesenchymal Transition as a Source for Carcinoma-Associated Fibroblasts

Zeisberg, E. M., Potenta, S., Xie, L., Zeisberg, M., & Kalluri, R. (2007) · Cancer Research · doi:10.1158/0008-5472.can-07-3127 · Cited by 1,011 · see citing works

Blood stem cells emerge from aortic endothelium by a novel type of cell transition

Kissa, K., & Herbomel, P. (2010) · Nature · doi:10.1038/nature08761 · Cited by 961 · see citing works

In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium

Boisset, J.-C., van Cappellen, W. A., Andrieu‐Soler, C., Galjart, N., Dzierzak, E. A., & Robin, C. (2010) · Nature · doi:10.1038/nature08764 · Cited by 951 · see citing works

Fibroblasts in Kidney Fibrosis Emerge via Endothelial-to-Mesenchymal Transition

Zeisberg, E. M., Potenta, S. E., Sugimoto, H., Zeisberg, M., & Kalluri, R. (2008) · Journal of the American Society of Nephrology · doi:10.1681/asn.2008050513 · Cited by 878 · see citing works

Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma

Huse, J. T., & Holland, E. C. (2010) · Nature reviews. Cancer · doi:10.1038/nrc2818 · Cited by 765 · see citing works

Conversion of vascular endothelial cells into multipotent stem-like cells

Medici, D., Shore, E. M., Lounev, V. Y., Kaplan, F. S., Kalluri, R., & Olsen, B. R. (2010) · Nature Medicine · doi:10.1038/nm.2252 · Cited by 678 · see citing works

The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage

Lancrin, C., Sroczyńska, P., Stephenson, C., Allen, T., Kouskoff, V., & Lacaud, G. (2009) · Nature · doi:10.1038/nature07679 · Cited by 634 · see citing works

Continuous single-cell imaging of blood generation from haemogenic endothelium

Eilken, H. M., Nishikawa, S., & Schroeder, T. (2009) · Nature · doi:10.1038/nature07760 · Cited by 572 · see citing works

The role of endothelial-to-mesenchymal transition in cancer progression

Potenta, S. E., Zeisberg, E. M., & Kalluri, R. (2008) · British Journal of Cancer · doi:10.1038/sj.bjc.6604662 · Cited by 553 · see citing works

Perivascular Nitric Oxide Activates Notch Signaling and Promotes Stem-like Character in PDGF-Induced Glioma Cells

Charles, N., Ozawa, T., Squatrito, M., Bleau, A.-M., Brennan, C. W., Hambardzumyan, D., & Holland, E. C. (2010) · Cell Stem Cell · doi:10.1016/j.stem.2010.01.001 · Cited by 550 · see citing works

VEGF Inhibits Tumor Cell Invasion and Mesenchymal Transition through a MET/VEGFR2 Complex

Lu, K. V., Chang, J. P., Parachoniak, C. A., Pandika, M. M., Aghi, M. K., Meyronet, D., Isachenko, N., Fouse, S. D., Phillips, J. J., Cheresh, D. A., et al. (2012) · Cancer Cell · doi:10.1016/j.ccr.2012.05.037 · Cited by 550 · see citing works

Transdifferentiation of glioblastoma cells into vascular endothelial cells

Soda, Y., Marumoto, T., Friedmann‐Morvinski, D., Soda, M., Liu, F., Michiue, H., Pastorino, S., Yang, M., Hoffman, R. M., Kesari, S., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1016030108 · Cited by 516 · see citing works

EndMT contributes to the onset and progression of cerebral cavernous malformations

Maddaluno, L., Rudini, N., Cuttano, R., Bravi, L., Giampietro, C., Corada, M., Ferrarini, L., Orsenigo, F., Papa, E., Boulday, G., et al. (2013) · Nature · doi:10.1038/nature12207 · Cited by 486 · see citing works

Mechanisms of Glioma-Associated Neovascularization

Hardee, M. E., & Zagzag, D. (2012) · American Journal Of Pathology · doi:10.1016/j.ajpath.2012.06.030 · Cited by 476 · see citing works

Genes that Distinguish Physiological and Pathological Angiogenesis

Seaman, S., Stevens, J., Yang, M., Logsdon, D. L., Graff‐Cherry, C., & Croix, B. S. (2007) · Cancer Cell · doi:10.1016/j.ccr.2007.04.017 · Cited by 419 · see citing works

TGF-β signaling mediates endothelial to mesenchymal transition (EndMT) during vein graft remodeling

Cooley, B., Nevado, J., Mellad, J., Yang, D., Hilaire, C. S., Negro, A., Fang, F., Chen, G.-B., Hong, S., Walts, A., et al. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3006927 · Cited by 414 · see citing works

Epithelial-to-Mesenchymal and Endothelial-to-Mesenchymal Transition

Kovacic, J. C., Mercader, N., Torres, M., Boehm, M., & Fuster, V. (2012) · Circulation · doi:10.1161/circulationaha.111.040352 · Cited by 402 · see citing works

TGF-β inhibition of endothelial cell proliferation: Alteration of EGF binding and EGF-induced growth-regulatory (competence) gene expression

Takehara, K., LeRoy, E. C., & Grotendorst, G. R. (1987) · Cell · doi:10.1016/0092-8674(87)90294-7 · Cited by 342 · see citing works

Fibroblast-specific protein 1 identifies an inflammatory subpopulation of macrophages in the liver

Österreicher, C. H., Penz-Österreicher, M., Grivennikov, S. I., Gumá, M., Koltsova, E. K., Datz, C., Šášik, R., Hardiman, G., Karin, M., & Brenner, D. A. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1017547108 · Cited by 337 · see citing works

HGF/c-Met Acts as an Alternative Angiogenic Pathway in Sunitinib-Resistant Tumors

Shojaei, F., Lee, J. H., Simmons, B. H., Wong, A., Esparza, C. O., Plumlee, P. A., Feng, J., Stewart, A., Hu‐Lowe, D. D., & Christensen, J. G. (2010) · Cancer Research · doi:10.1158/0008-5472.can-10-0489 · Cited by 321 · see citing works

Lymphoma-Specific Genetic Aberrations in Microvascular Endothelial Cells in B-Cell Lymphomas

Streubel, B., Chott, A., Huber, D., Exner, M., Jaeger, U., Wagner, O. F., & Schwarzinger, I. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa033153 · Cited by 318 · see citing works

Endothelial-Myofibroblast Transition Contributes to the Early Development of Diabetic Renal Interstitial Fibrosis in Streptozotocin-Induced Diabetic Mice

Li, J., Qu, X., & Bertram, J. F. (2009) · American Journal Of Pathology · doi:10.2353/ajpath.2009.090096 · Cited by 317 · see citing works

FGF Regulates TGF-β Signaling and Endothelial-to-Mesenchymal Transition via Control of let-7 miRNA Expression

Chen, P., Qin, L., Barnes, C., Charissé, K., Yi, T., Zhang, X., Ali, R., Medina, P. P., Yu, J., Slack, F. J., et al. (2012) · Cell Reports · doi:10.1016/j.celrep.2012.10.021 · Cited by 305 · see citing works

VEGF and c-Met Blockade Amplify Angiogenesis Inhibition in Pancreatic Islet Cancer

You, W., Sennino, B., Williamson, C. W., Falcón, B. L., Hashizume, H., Yao, L., Aftab, D. T., & McDonald, D. M. (2011) · Cancer Research · doi:10.1158/0008-5472.can-10-2527 · Cited by 262 · see citing works

Activation of NF-κB Is Essential for Hepatocyte Growth Factor-Mediated Proliferation and Tubulogenesis

Müller, M., Morotti, A., & Ponzetto, C. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.4.1060-1072.2002 · Cited by 129 · see citing works

Angiogenic Property of Hepatocyte Growth Factor Is Dependent on Upregulation of Essential Transcription Factor for Angiogenesis, ets-1

Tomita, N., Morishita, R., Taniyama, Y., Koike, H., Aoki, M., Shimizu, H., Matsumoto, K., Nakamura, T., Kaneda, Y., & Ogihara, T. (2003) · Circulation · doi:10.1161/01.cir.0000055331.41937.aa · Cited by 115 · see citing works

Kaposi Sarcoma Herpesvirus Promotes Endothelial-to-Mesenchymal Transition through Notch-Dependent Signaling

Gasperini, P., Espígol‐Frigolé, G., McCormick, P. J., Salvucci, O., Maric, D., Uldrick, T. S., Polizzotto, M. N., Yarchoan, R., & Tosato, G. (2012) · Cancer Research · doi:10.1158/0008-5472.can-11-3067 · Cited by 115 · see citing works

Profilin-1 phosphorylation directs angiocrine expression and glioblastoma progression through HIF-1α accumulation

Fan, Y., Potdar, A. A., Gong, Y., Eswarappa, S. M., Donnola, S. B., Lathia, J. D., Hambardzumyan, D., Rich, J. N., & Fox, P. L. (2014) · Nature Cell Biology · doi:10.1038/ncb2954 · Cited by 93 · see citing works

Hepatocyte Growth Factor Enhances MMP Activity in Human Endothelial Cells

Wang, H., & Keiser, J. A. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.2852 · Cited by 77 · see citing works

Somatic cell type specific gene transfer reveals a tumor‐promoting function for p21Waf1/Cip1

Liu, Y., Yeh, N., Zhu, X.-H., Leversha, M. A., Cordon‐Cardo, C., Ghossein, R. A., Singh, B., Holland, E. C., & Koff, A. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601886 · Cited by 52 · see citing works

Cyclin D1 and cdk4 mediate development of neurologically destructive oligodendroglioma

Ciznadija, D., Liu, Y., Pyonteck, S. M., Holland, E. C., & Koff, A. (2011) · Cancer Research · doi:10.1158/0008-5472.can-11-1031 · Cited by 44 · see citing works

Pathological angiogenesis: mechanisms and therapeutic strategies

Dudley, A. C., & Griffioen, A. W. (2023) · Angiogenesis · doi:10.1007/s10456-023-09876-7 · Cited by 529 · see citing works

Mutational Landscape of Secondary Glioblastoma Guides MET-Targeted Trial in Brain Tumor

Hu, H., Mu, Q., Bao, Z., Chen, Y., Liu, Y., Chen, J., Wang, K., Wang, Z., Nam, Y., Jiang, B., et al. (2018) · Cell · doi:10.1016/j.cell.2018.09.038 · Cited by 343 · see citing works

Challenges in glioblastoma research: focus on the tumor microenvironment

Bikfalvi, A., da Costa, C. A., Avril, T., Barnier, J., Bauchet, L., Brisson, L., Cartron, P., Castel, H., Chevet, É., Chneiweiss, H., et al. (2022) · Trends in cancer · doi:10.1016/j.trecan.2022.09.005 · Cited by 309 · see citing works

The role of tumor microenvironment in therapeutic resistance

Son, B., Lee, S., Youn, H., Kim, E., Kim, W., & Youn, B. (2016) · Oncotarget · doi:10.18632/oncotarget.13907 · Cited by 305 · see citing works

Vascular niche IL-6 induces alternative macrophage activation in glioblastoma through HIF-2α

Wang, Q., He, Z., Huang, M., Liu, T., Wang, Y., Xu, H., Duan, H., Ma, P., Zhang, L., Zamvil, S. S., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-03050-0 · Cited by 279 · see citing works

Molecular Mechanisms of Treatment Resistance in Glioblastoma

Ou, A. C., Yung, W. K. A., & Majd, N. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms22010351 · Cited by 270 · see citing works

Endothelial-to-Mesenchymal Transition

Bischoff, J. E. (2019) · Circulation Research · doi:10.1161/circresaha.119.314813 · Cited by 234 · see citing works

Endothelial-to-Mesenchymal Transition in Cancer

Clere, N., Renault, S., & Corre, I. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00747 · Cited by 199 · see citing works

Exosomal miR-155 from M1-polarized macrophages promotes EndoMT and impairs mitochondrial function via activating NF-κB signaling pathway in vascular endothelial cells after traumatic spinal cord injury

Ge, X., Tang, P., Rong, Y., Jiang, D., Lu, X., Ji, C., Wang, J., Huang, C., Duan, A., Liu, Y., et al. (2021) · Redox Biology · doi:10.1016/j.redox.2021.101932 · Cited by 197 · see citing works

Tumor angiogenesis revisited: Regulators and clinical implications

Ronca, R., Benkheil, M., Mitola, S. M. F., Struyf, S., & Liekens, S. (2017) · Medicinal Research Reviews · doi:10.1002/med.21452 · Cited by 193 · see citing works

Lnc-TALC promotes O6-methylguanine-DNA methyltransferase expression via regulating the c-Met pathway by competitively binding with miR-20b-3p

Wu, P., Cai, J., Chen, Q., Han, B., Meng, X., Li, Y., Li, Z., Wang, R., Lin, L., Duan, C., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-10025-2 · Cited by 181 · see citing works

MET in glioma: signaling pathways and targeted therapies

Cheng, F., & Guo, D. (2019) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-019-1269-x · Cited by 164 · see citing works

EMT‐ and MET‐related processes in nonepithelial tumors: importance for disease progression, prognosis, and therapeutic opportunities

Kahlert, U. D., Joseph, J. V., & Kruyt, F. A. E. (2017) · Molecular Oncology · doi:10.1002/1878-0261.12085 · Cited by 158 · see citing works

Synergistic immunotherapy of glioblastoma by dual targeting of IL-6 and CD40

Yang, F., He, Z., Duan, H., Zhang, D., Li, J., Yang, H., Dorsey, J. F., Zou, W., Nabavizadeh, S. A., Bagley, S. J., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-23832-3 · Cited by 157 · see citing works

PDGF-mediated mesenchymal transformation renders endothelial resistance to anti-VEGF treatment in glioblastoma

Liu, T., Ma, W., Xu, H., Huang, M., Zhang, D., He, Z., Zhang, L., Brem, S. S., O’Rourke, D. M., Gong, Y., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-05982-z · Cited by 152 · see citing works

Dual functionalized brain-targeting nanoinhibitors restrain temozolomide-resistant glioma via attenuating EGFR and MET signaling pathways

Meng, X., Zhao, Y., Han, B. R., Zha, C., Zhang, Y., Li, Z., Wu, P., Qi, T., Jiang, C., Liu, Y., et al. (2020) · Nature Communications · doi:10.1038/s41467-019-14036-x · Cited by 148 · see citing works

Targeting PAK4 to reprogram the vascular microenvironment and improve CAR‐T immunotherapy for glioblastoma

Ma, W., Wang, Y., Zhang, R., Yang, F., Zhang, D., Huang, M., Zhang, L., Dorsey, J. F., Binder, Z. A., O’Rourke, D. M., et al. (2020) · Nature Cancer · doi:10.1038/s43018-020-00147-8 · Cited by 143 · see citing works

Endothelial cells in tumor microenvironment: insights and perspectives

Leone, P., Malerba, E., Susca, N., Favoino, E., Perosa, F., Brunori, G., Prete, M., & Racanelli, V. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1367875 · Cited by 146 · see citing works

PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy

Zhang, D., Li, A. M., Hu, G., Huang, M., Yang, F., Zhang, L., Wellen, K. E., Xu, X., Conn, C. S., Zou, W., et al. (2023) · Cell Metabolism · doi:10.1016/j.cmet.2023.01.010 · Cited by 141 · see citing works

Wnt-mediated endothelial transformation into mesenchymal stem cell–like cells induces chemoresistance in glioblastoma

Huang, M., Zhang, D., Wu, J. Y., Xing, K., Yeo, E., Li, C., Zhang, L., Holland, E. C., Yao, L., Qin, L., et al. (2020) · Science Translational Medicine · doi:10.1126/scitranslmed.aay7522 · Cited by 138 · see citing works

A Systematic Review of Glioblastoma-Targeted Therapies in Phases II, III, IV Clinical Trials

Silva, E. C. D., Mercier, M.-C., Étienne-Selloum, N., Dontenwill, M., & Choulier, L. (2021) · Cancers · doi:10.3390/cancers13081795 · Cited by 130 · see citing works

Vascular Microenvironment, Tumor Immunity and Immunotherapy

Lamplugh, Z. L., & Fan, Y. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.811485 · Cited by 126 · see citing works

Fibronectin in malignancy: Cancer-specific alterations, protumoral effects, and therapeutic implications

Rick, J. W., Chandra, A., Ore, C. L. D., Nguyen, A. T., Yagnik, G., & Aghi, M. K. (2019) · Seminars in Oncology · doi:10.1053/j.seminoncol.2019.08.002 · Cited by 114 · see citing works

The role of MET in chemotherapy resistance

Wood, G. E., Hockings, H., Hilton, D. M., & Kermorgant, S. (2021) · Oncogene · doi:10.1038/s41388-020-01577-5 · Cited by 113 · see citing works

Circulating Glioma Cells Exhibit Stem Cell-like Properties

Liu, T., Xu, H., Huang, M., Ma, W., Saxena, D., Lustig, R. A., Alonso‐Basanta, M., Zhang, Z., O’Rourke, D. M., Zhang, L., et al. (2018) · Cancer Research · doi:10.1158/0008-5472.can-18-0650 · Cited by 112 · see citing works

Endothelial-to-mesenchymal transition in anticancer therapy and normal tissue damage

Choi, K. J., Nam, J.-K., Kim, J.-H., Choi, S., & Lee, Y. (2020) · Experimental & Molecular Medicine · doi:10.1038/s12276-020-0439-4 · Cited by 112 · see citing works

EndMT: A promising and controversial field

Hong, L., Du, X., Li, W., Mao, Y., Sun, L., & Li, X. (2018) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2018.07.005 · Cited by 100 · see citing works

Glioblastoma Therapy in the Age of Molecular Medicine

Geraldo, L. H., Garcia, C., da Fonseca, A. C. C., Dubois, L. G., Spohr, T. C. L. D. S. E., Matias, D., Magalhães, E. S. D. C., do Amaral, R. F., da Rosa, B. G., Grimaldi, I., et al. (2018) · Trends in cancer · doi:10.1016/j.trecan.2018.11.002 · Cited by 92 · see citing works

Fine‐tuning vascular fate during endothelial–mesenchymal transition

Xiao, L., & Dudley, A. C. (2016) · The Journal of Pathology · doi:10.1002/path.4814 · Cited by 90 · see citing works

Navigating tumor angiogenesis: therapeutic perspectives and myeloid cell regulation mechanism

Yang, F., Lee, G., & Fan, Y. (2024) · Angiogenesis · doi:10.1007/s10456-024-09913-z · Cited by 84 · see citing works

FLASH radiation reprograms lipid metabolism and macrophage immunity and sensitizes medulloblastoma to CAR-T cell therapy

Ni, H., Reitman, Z. J., Zou, W., Akhtar, M. N., Paul, R., Huang, M., Zhang, D., Zheng, H., Zhang, R., Ma, R., et al. (2025) · Nature Cancer · doi:10.1038/s43018-025-00905-6 · Cited by 86 · see citing works

MiR-206 inhibits epithelial ovarian cancer cells growth and invasion via blocking c-Met/AKT/mTOR signaling pathway

Dai, C., Xie, Y., Zhuang, X., & Yuan, Z. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.05.077 · Cited by 77 · see citing works

Tumor Vessels Fuel the Fire in Glioblastoma

Rosińska, S., & Gavard, J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22126514 · Cited by 77 · see citing works

Role and Therapeutic Targeting of the HGF/MET Pathway in Glioblastoma

Cruickshanks, N. A., Zhang, Y., Yuan, F., Pahuski, M., Gibert, M. K., & Abounader, R. (2017) · Cancers · doi:10.3390/cancers9070087 · Cited by 74 · see citing works

Autophagy mediates glucose starvation-induced glioblastoma cell quiescence and chemoresistance through coordinating cell metabolism, cell cycle, and survival

Wang, L. Y., Shang, Z., Zhou, Y., Hu, X., Chen, Y., Fan, Y., Wei, X., Wu, L. L., Liang, Q., Zhang, J., et al. (2018) · Cell Death and Disease · doi:10.1038/s41419-017-0242-x · Cited by 73 · see citing works

Dual inhibition of Akt and c‐Met as a second‐line therapy following acquired resistance to sorafenib in hepatocellular carcinoma cells

Han, P., Li, H., Jiang, X. L., Zhai, B., Tan, G., Zhao, D., Qiao, H., Liu, B., Jiang, H., & Sun, X. (2017) · Molecular Oncology · doi:10.1002/1878-0261.12039 · Cited by 69 · see citing works

Small-molecule toosendanin reverses macrophage-mediated immunosuppression to overcome glioblastoma resistance to immunotherapy

Yang, F., Zhang, D., Jiang, H., Ye, J., Zhang, L., Bagley, S. J., Winkler, J. D., Gong, Y., & Fan, Y. (2023) · Science Translational Medicine · doi:10.1126/scitranslmed.abq3558 · Cited by 69 · see citing works

Cancer stem-like cells directly participate in vasculogenic mimicry channels in triple-negative breast cancer

Sun, H., Yao, N., Siqi, C., Linqi, L., Shiqi, L., Zhao, Y., Guanjie, S., Danfang, Z., & Zhi, Y. (2019) · Cancer Biology and Medicine · doi:10.20892/j.issn.2095-3941.2018.0209 · Cited by 70 · see citing works

A phase 1 and randomized, placebo‐controlled phase 2 trial of bevacizumab plus dasatinib in patients with recurrent glioblastoma: Alliance/North Central Cancer Treatment Group N0872

Galanis, E., Anderson, S. K., Twohy, E. L., Carrero, X. W., Dixon, J. G., Tran, D. D., Jeyapalan, S. A., Anderson, D. M., Kaufmann, T. J., Feathers, R. W., et al. (2019) · Cancer · doi:10.1002/cncr.32340 · Cited by 69 · see citing works

Regulation of Partial and Reversible Endothelial-to-Mesenchymal Transition in Angiogenesis

Fang, J. S., Hultgren, N. W., & Hughes, C. C. W. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.702021 · Cited by 65 · see citing works

Cancer-associated fibroblast-derived PAI-1 promotes lymphatic metastasis via the induction of EndoMT in lymphatic endothelial cells

Wei, W.-F., Zhou, H., Chen, P., Huang, X., Huang, L., Liang, L.-J., Guo, C.-H., Zhou, C.-F., Yu, L., Fan, L., et al. (2023) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-023-02714-0 · Cited by 64 · see citing works

Temporal DNA-PK activation drives genomic instability and therapy resistance in glioma stem cells.

Wang, Y., Xu, H., Liu, T.-R., Huang, M.-G., Butter, P., Li, C.-S., Zhang, L., Kao, G., Gong, Y.-Q., Maity, A., et al. (2018) · JCI Insight · doi:10.1172/jci.insight.98096 · Cited by 54 · see citing works

Roles of TGF-β signals in tumor microenvironment via regulation of the formation and plasticity of vascular system

Watabe, T., Takahashi, K., Pietras, K., & Yoshimatsu, Y. (2023) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2023.04.007 · Cited by 62 · see citing works

Mesenchymal Transformation: The Rosetta Stone of Glioblastoma Pathogenesis and Therapy Resistance

Azam, Z., To, S. S. T., & Tannous, B. A. (2020) · Advanced Science · doi:10.1002/advs.202002015 · Cited by 59 · see citing works

Microenvironmental regulation of solid tumour resistance to CAR T cell therapy

Lamplugh, Z. L., Wellhausen, N., June, C. H., & Fan, Y. (2025) · Nature reviews. Immunology · doi:10.1038/s41577-025-01229-3 · Cited by 71 · see citing works

Angiogenesis and targeted therapy in the tumour microenvironment: From basic to clinical practice

Yang, S., Fang, Y., Ma, Y., Wang, F., Wang, Y., Jia, J., Yang, Y., Sun, W., Zhou, Q., & Li, Z. (2025) · Clinical and Translational Medicine · doi:10.1002/ctm2.70313 · Cited by 52 · see citing works

YAP Orchestrates Heterotypic Endothelial Cell Communication via HGF/c-MET Signaling in Liver Tumorigenesis

Thomann, S., Weiler, S. M. E., Marquard, S., Rose, F., Ball, C. R., Tóth, M., Wei, T., Sticht, C., Fritzsche, S., Roessler, S. K., et al. (2020) · Cancer Research · doi:10.1158/0008-5472.can-20-0242 · Cited by 50 · see citing works

An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma

Yang, F., Akhtar, M. N., Zhang, D., El-Mayta, R. D., Shin, J., Dorsey, J. F., Zhang, L., Xu, X., Guo, W., Bagley, S. J., et al. (2024) · Science Advances · doi:10.1126/sciadv.adj4678 · Cited by 44 · see citing works

ETS transcription factors: Multifaceted players from cancer progression to tumor immunity

Wang, Y., Huang, Z., Sun, M., Huang, W., & Xia, L. (2023) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2023.188872 · Cited by 46 · see citing works

Overcoming physical stromal barriers to cancer immunotherapy

Chung, S. W., Xie, Y., & Suk, J. S. (2021) · Drug Delivery and Translational Research · doi:10.1007/s13346-021-01036-y · Cited by 42 · see citing works

LncRNA MIR155HG Promotes Temozolomide Resistance by Activating the Wnt/β-Catenin Pathway Via Binding to PTBP1 in Glioma

He, X., Sheng, J., Yu, W., Wang, K., Zhu, S., & Liu, Q. (2020) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-020-00898-z · Cited by 42 · see citing works

MicroRNA-128-3p Mediates Lenvatinib Resistance of Hepatocellular Carcinoma Cells by Downregulating c-Met

Xu, X., Jiang, W., Han, P., Zhang, J., Tong, L., & Sun, X. (2022) · Journal of Hepatocellular Carcinoma · doi:10.2147/jhc.s349369 · Cited by 41 · see citing works

Reprogramming endothelial cells to empower cancer immunotherapy

Cleveland, A. H., & Fan, Y. (2023) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2023.11.002 · Cited by 43 · see citing works

Oligosaccharyltransferase Inhibition Reduces Receptor Tyrosine Kinase Activation and Enhances Glioma Radiosensitivity

Baro, M., Sambrooks, C. L., Quijano, A., Saltzman, W. M., & Contessa, J. N. (2018) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-18-0792 · Cited by 40 · see citing works

Extracellular proteolysis in glioblastoma progression and therapeutics

Quesnel, A., Karagiannis, G. S., & Filippou, P. S. (2020) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2020.188428 · Cited by 40 · see citing works

Current and emerging concepts for systemic treatment of metastatic colorectal cancer

Steup, C., Kennel, K. B., Neurath, M. F., Fichtner-Feigl, S., & Greten, F. R. (2025) · Gut · doi:10.1136/gutjnl-2025-335412 · Cited by 39 · see citing works

TGF-β induces oncofetal fibronectin that, in turn, modulates TGF-β superfamily signaling in endothelial cells

Ventura, E., Weller, M., Macnair, W., Eschbach, K., Beisel, C., Cordazzo, C., Claassen, M., Zardi, L., & Burghardt, I. (2017) · Journal of Cell Science · doi:10.1242/jcs.209619 · Cited by 37 · see citing works

PI3K/Akt signaling in urological cancers: Tumorigenesis function, therapeutic potential, and therapy response regulation

Rezaei, S., Nikpanjeh, N., Rezaee, A., Gholami, S., Hashemipour, R., Biavarz, N., Yousefi, F., Tashakori, A., Salmani, F., Rajabi, R., et al. (2023) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2023.175909 · Cited by 36 · see citing works

NEO212, a conjugate of temozolomide and perillyl alcohol, blocks the endothelial-to-mesenchymal transition in tumor-associated brain endothelial cells in glioblastoma

Marín‐Ramos, N. I., Jhaveri, N., Thein, T. Z., Fayngor, R. A., Chen, T. C., & Hofman, F. M. (2018) · Cancer Letters · doi:10.1016/j.canlet.2018.10.034 · Cited by 34 · see citing works

Mechanosensory entities and functionality of endothelial cells

Mierke, C. T. (2024) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1446452 · Cited by 32 · see citing works

Vascular Detransformation for Cancer Therapy

Fan, Y. (2019) · Trends in cancer · doi:10.1016/j.trecan.2019.05.007 · Cited by 28 · see citing works

Verbascoside suppresses the migration and invasion of human glioblastoma cells via targeting c-Met-mediated epithelial-mesenchymal transition

Hei, B., Wang, J., Wu, G., Ouyang, J., & Liu, R.-E. (2019) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2019.05.096 · Cited by 27 · see citing works

The driving mechanism and targeting value of mimicry between vascular endothelial cells and tumor cells in tumor progression

Ma, X., Geng, Z., Wang, S., Yu, Z., Liu, T., Guan, S., Du, S., & Zhu, C. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115029 · Cited by 27 · see citing works

Reduced EGFR and increased miR-221 is associated with increased resistance to temozolomide and radiotherapy in glioblastoma

Areeb, Z., Stuart, S. F., West, A. J., Gomez, J., Nguyen, H. P. T., Paradiso, L., Zulkifli, A., Jones, J., Kaye, A. H., Morokoff, A. P., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-74746-x · Cited by 27 · see citing works

Nanomedicine Revisited: Next Generation Therapies for Brain Cancer

Bhargav, A. G., Mondal, S. K., Garcia, C. A., Green, J. J., & Quiñones‐Hinojosa, A. (2020) · Advanced Therapeutics · doi:10.1002/adtp.202000118 · Cited by 26 · see citing works

Endothelial Cells Promote Docetaxel Resistance of Prostate Cancer Cells by Inducing ERG Expression and Activating Akt/mTOR Signaling Pathway

Zhou, W., Su, Y., Zhang, Y., Han, B., Liu, H., & Wang, X. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.584505 · Cited by 26 · see citing works

Endothelial-to-mesenchymal transition in tumour progression and its potential roles in tumour therapy

Yin, Z., & Wang, L. (2023) · Annals of Medicine · doi:10.1080/07853890.2023.2180155 · Cited by 26 · see citing works

The Pleiotropic Role of L1CAM in Tumor Vasculature

Angiolini, F., & Cavallaro, U. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18020254 · Cited by 24 · see citing works

SHP2 protects endothelial cell barrier through suppressing VE‐cadherin internalization regulated by MET‐ARF1

Zhang, J., Huang, J., Qi, T., Huang, Y., Lu, Y., Zhan, T., Gong, H., Zhu, Z., Shi, Y., Zhou, J., et al. (2018) · The FASEB Journal · doi:10.1096/fj.201800284r · Cited by 23 · see citing works

Brain-targeted antigen-generating nanoparticles improve glioblastoma prognosis

Wang, W., Zhang, M., Zhang, Q., Mohammadniaei, M., Shen, J., & Sun, Y. (2022) · Journal of Controlled Release · doi:10.1016/j.jconrel.2022.10.037 · Cited by 22 · see citing works

Lenvatinib for effectively treating antiangiogenic drug-resistant nasopharyngeal carcinoma

Sun, Q., Wang, Y., Ji, H. L., Sun, X., Xie, S., Chen, L., Li, S., Zeng, W., Chen, R., Tang, Q., et al. (2022) · Cell Death and Disease · doi:10.1038/s41419-022-05171-3 · Cited by 21 · see citing works

Neovascularization directed by CAVIN1/CCBE1/VEGFC confers TMZ-resistance in glioblastoma

Wang, M., Xia, D., Xu, D., Yin, Y., Xu, F., Zhang, B., Li, K., Yang, Z., & Zou, J. (2023) · Cancer Letters · doi:10.1016/j.canlet.2023.216593 · Cited by 21 · see citing works

Chloride intracellular channel protein 2 is secreted and inhibits MMP14 activity, while preventing tumor cell invasion and metastasis

Ozaki, S., Akihiro, U., Yano, H., Ohsumi, S., Sumida, Y., Hayase, E., Usa, E., Islam, A., Choudhury, M. E., Nishi, Y., et al. (2021) · Neoplasia · doi:10.1016/j.neo.2021.06.001 · Cited by 20 · see citing works

Shifting Shapes: The Endothelial-to-Mesenchymal Transition as a Driver for Cancer Progression

Giordanengo, L., Proment, A., Botta, V., Picca, F., Munir, H., Tao, J., Olivero, M., Taulli, R., Bersani, F., Sangiolo, D., et al. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26136353 · Cited by 20 · see citing works

Endothelial plasticity drives aberrant vascularization and impedes cardiac repair after myocardial infarction

Huang, M., Yang, F., Zhang, D., Lin, M., Duan, H., El-Mayta, R. D., Zhang, L., Qin, L., Shewale, S. V., Pei, L., et al. (2022) · Nature Cardiovascular Research · doi:10.1038/s44161-022-00047-3 · Cited by 19 · see citing works

Yes-associated protein promotes endothelial-to-mesenchymal transition of endothelial cells in choroidal neovascularization fibrosis

Zou, R., Xu, Y., Shen, M.-Q., Zhang, X., & Yuan, Y. (2022) · International Journal of Ophthalmology · doi:10.18240/ijo.2022.05.03 · Cited by 19 · see citing works

Co-culture models for investigating cellular crosstalk in the glioma microenvironment

Niu, X., Zhang, Y., & Wang, Y. (2023) · Cancer Pathogenesis and Therapy · doi:10.1016/j.cpt.2023.11.002 · Cited by 17 · see citing works

Spatial transcriptomics and multi-omics reveal relapse and resistance mechanisms of EndMT-derived CAFs mediated by TNC and FLNC in glioblastoma

Li, J., Xia, D., Zhou, Y., Hu, Y., Yang, Z., Yin, Y., Wang, J., Zhang, B., Gong, L., Li, K., et al. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-06743-5 · Cited by 16 · see citing works

Loss of Endothelial Cell Matrix Metalloproteinase 14 Reduces Melanoma Growth and Metastasis by Increasing Tumor Vessel Stability

Kümper, M., Hessenthaler, S., Zamek, J., Niland, S., Pach, E., Mauch, C., & Zigrino, P. (2021) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2021.12.016 · Cited by 16 · see citing works

Diffuse Large B-Cell Lymphoma Promotes Endothelial-to-Mesenchymal Transition via WNT10A/Beta-Catenin/Snail Signaling

Sun, X., Fang, J., Ye, F., Zhang, S., Huang, H., Hou, J., & Wang, T. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.871788 · Cited by 16 · see citing works

Understanding the Role of Endothelial Cells in Glioblastoma: Mechanisms and Novel Treatments

Hovis, G. E. A., Chandra, N. V., Kejriwal, N., Hsieh, K. J.-Y., Chu, A., Yang, I., & Wadehra, M. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25116118 · Cited by 15 · see citing works

Spatial analysis of tissue immunity and vascularity by light sheet fluorescence microscopy

Zhang, D., Cleveland, A. H., Krimitza, E., Han, K., Yi, C., Stout, A. L., Zou, W., Dorsey, J. F., Gong, Y., & Fan, Y. (2024) · Nature Protocols · doi:10.1038/s41596-023-00941-5 · Cited by 14 · see citing works

TGF-β1 Promotes Angiogenesis via Endothelial-to-Mesenchymal Transition in Infantile Hemangioma

Gong, X., Qiu, T., Zhou, J., Yang, K., Xiang, S., Zhang, Z., Lan, Y., Zhang, X., Zhou, Z., Yang, C., et al. (2025) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.125.322793 · Cited by 13 · see citing works

Paeoniflorin Inhibits EMT and Angiogenesis in Human Glioblastoma via K63-Linked C-Met Polyubiquitination-Dependent Autophagic Degradation

Liu, Z., Wang, Z., Chen, D., Liu, X., Yu, G., Zhang, Y., Chen, C., Xu, R., Wang, Y., & Liu, R. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.785345 · Cited by 13 · see citing works

Advancing precision medicine in gliomas through single-cell sequencing: unveiling the complex tumor microenvironment

Li, J., Zhang, Y., Liang, C., Yan, X., Hui, X., & Liu, Q. (2024) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1396836 · Cited by 12 · see citing works

Novel approaches to combat chemoresistance against glioblastomas

Towner, R. A., Zalles, M., Saunders, D., & Smith, N. (2020) · Cancer Drug Resistance · doi:10.20517/cdr.2020.38 · Cited by 12 · see citing works

Implication of Irisin in Different Types of Cancer: A Systematic Review and Meta-Analysis

Vliora, M., Nintou, E., Karligiotou, E., Ioannou, L. G., Grillo, E., Mitola, S. M. F., & Flouris, A. D. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23179971 · Cited by 12 · see citing works

Enolase-phosphatase 1 as a novel potential malignant glioma indicator promotes cell proliferation and migration

Su, L., Yang, K., Li, S., Liu, C., Han, J., Zhang, Y., & Xu, G. (2018) · Oncology Reports · doi:10.3892/or.2018.6592 · Cited by 12 · see citing works

Role of vascular endothelium and exosomes in cancer progression and therapy (Review)

Dai, Y., Yao, Y., He, Y., & Hu, X. (2024) · International Journal of Oncology · doi:10.3892/ijo.2024.5712 · Cited by 11 · see citing works

Mesenchymal Epithelial Transition (MET): A Key Player in Chemotherapy Resistance and an Emerging Target for Potentiating Cancer Immunotherapy

To, K. K. W., & Cho, W. C. S. (2022) · Current Cancer Drug Targets · doi:10.2174/1568009622666220307105107 · Cited by 11 · see citing works

The strange Microenvironment of Glioblastoma

Brisson, L., Geraldo, L. H., Bikfalvi, A., & Mathivet, T. (2023) · Revue Neurologique · doi:10.1016/j.neurol.2023.03.007 · Cited by 10 · see citing works

Suppression of p53-inducible gene 3 is significant for glioblastoma progression and predicts poor patient prognosis

Quan, J., Li, Y., Jin, M., Chen, D., Jin, M., & Jin, M. (2017) · Tumor Biology · doi:10.1177/1010428317694572 · Cited by 10 · see citing works

Interleukin 6 and cancer resistance in glioblastoma multiforme

Detchou, D. K. E. D., & Barrie, U. (2024) · Neurosurgical Review · doi:10.1007/s10143-024-02783-5 · Cited by 9 · see citing works

Endothelial transdifferentiation of glioma stem cells: a literature review

Buruiană, A., Florian, I. Ş., Florian, I. A., Şoriţău, O., & Șușman, S. (2025) · Acta Neuropathologica Communications · doi:10.1186/s40478-025-02031-x · Cited by 9 · see citing works

c-Met Expression Is a Useful Marker for Prognosis Prediction in IDH-Mutant Lower-Grade Gliomas and IDH-Wildtype Glioblastomas

Ohba, S., Yamada, Y., Murayama, K., Pareira, E. S., Sasaki, H., Yamada, S., Abe, M., Hasegawa, M., & Hirose, Y. (2019) · World Neurosurgery · doi:10.1016/j.wneu.2019.03.040 · Cited by 9 · see citing works

Meningeal blood vessel blockage enhances anti-glioblastoma immunity

Gao, Y., Peng, Y., Cheng, J., Zhang, X., Zhong, J., Lu, C., Xing, X., Lai, Y., Sun, H., Zeng, X., et al. (2026) · Cell · doi:10.1016/j.cell.2025.12.045 · Cited by 11 · see citing works

Evolutionary Mechanisms of Cancer Suggest Rational Therapeutic Approaches

Balzerano, A., Paccosi, E., & Proietti‐De‐Santis, L. (2021) · Cytogenetic and Genome Research · doi:10.1159/000516530 · Cited by 8 · see citing works

Mouse Models to Evaluate the Functional Role of the Tumor Microenvironment in Cancer Progression and Therapy ResponsesPreprint

McAndrews, K. M., Mahadevan, K. K., & Kalluri, R. (2024) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a041411 · Cited by 8 · see citing works

Overexpression of c-Met is Associated with Poor Prognosis in Glioblastoma Multiforme: A Systematic Review and Meta-Analyses

Anton, J., Sudibio, S., Handoko, H., Permata, T. B. M., Kodrat, H., Nuryadi, E., Sofyan, H. R., Susanto, E., Mulyadi, R., Aman, R. A., et al. (2021) · Asian Pacific Journal of Cancer Prevention · doi:10.31557/apjcp.2021.22.10.3075 · Cited by 7 · see citing works

TPX2 Enhanced the Activation of the HGF/ETS-1 Pathway and Increased the Invasion of Endocrine-Independent Prostate Carcinoma Cells

Zhou, H., Liu, M., Shao, T., Xie, P., Zhu, S., Wang, W., Miao, Q., Peng, J., & Zhang, P. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.618540 · Cited by 7 · see citing works

Abstract 5222: Endothelial plasticity generates aberrant angiogenesis and therapy resistance in glioblastoma

Huang, M., & Fan, Y. (2015) · Cancer Research · doi:10.1158/1538-7445.am2015-5222

AI-11 * c-MET-MEDIATED ENDOTHELIAL-MESENCHYMAL TRANSITION DRIVES GLIOBLASTOMA PROGRESSION AND THERAPEUTIC RESISTANCE

Huang, M., Ma, P., Mitteer, R. A., & Fan, Y. (2014) · Neuro-Oncology · doi:10.1093/neuonc/nou238.11

ANGI-01. TRANSFORMATION OF TUMOR ENDOTHELIAL CELLS TO MESENCHYMAL STEM CELL-LIKE CELLS INDUCES THERAPY RESISTANCE IN GLIOBLASTOMA

Huang, M. (2016) · Neuro-Oncology · doi:10.1093/neuonc/now212.056

Chemotherapeutic Stress Induces Transdifferentiation of Glioblastoma Cells to Endothelial Cells and Promotes Vascular Mimicry

Baisiwala, S., Auffinger, B., Caragher, S. P., Shireman, J. M., Ahsan, R., Lee, G., Hasan, T., Park, C., Saathoff, M. R., Christensen, A. C., et al. (2019) · Stem Cells International · doi:10.1155/2019/6107456 · Cited by 45 · see citing works

TAMI-26. SINGLE-CELL TRANSCRIPTOME ANALYSIS REVEALS THAT ENDOTHELIAL TRANSFORMATION DRIVES GLIOBLASTOMA CHEMORESISTANCE VIA Wnt/β-CATENIN/MRP-1

Huang, M., Zhang, D., & Fan, Y. (2020) · Neuro-Oncology · doi:10.1093/neuonc/noaa215.914