The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
Efficacy of behavioral versus triazolam treatment in persistent sleep-onset insomnia
Abstract
OBJECTIVE: This study compared differential effects of behavioral therapy and triazolam in a clinical population with sleep-onset insomnia. Triazolam was hypothesized to decrease sleep latency and frequency and duration of awakening, with some effects during the first night's administration. But at follow-up, sleep measures were predicted to return to baseline levels. Behavioral treatment was hypothesized to effect sleep after 2 or more weeks of training which persisted at follow-up. METHOD: Thirty patients with average sleep latencies of 81.48 minutes, who reported chronic insomnia for an average of 2.6 years, were randomly assigned to one of two treatment groups: behavioral stimulus control/relaxation training and triazolam. RESULTS: Both treatments decreased sleep latency but differentially. Triazolam was effective immediately but maintained only some gains at follow-up. Behavioral treatment decreased sleep latency beginning the second week, when subjects expected no improvement, with gains maintained at follow-up. Comparisons showed that triazolam group latencies returned toward baseline, while behavioral group gains were maintained at follow-up. CONCLUSIONS: Triazolam treatment showed superior immediate treatment effects, while behavioral treatment showed superior treatment effects at follow-up, effects that accrued during the training period and differentially persisted at follow-up. One treatment strategy implied by these results would be to combine these two interventions concurrently. This would seem to use the immediate effects produced by the medication until the behavioral skills were learned, at which point medication would be terminated. This strategy could offer immediate relief and sustained effects at drug termination.
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“The recommended first-line treatment, Cognitive Behavioral Therapy for Insomnia (CBTI) does not carry these risks and is therefore preferable for reasons beyond demonstrated efficacy(244-248), efficacy relative to medications(249-253), and effectiveness(254).”
From Sleep: important considerations for the prevention of cardiovascular disease (2016) · cites this paper as [249]
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Behavioral and Pharmacological Therapies for Late-Life Insomnia: A Randomized Controlled Trial
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Metadata
- Authors
- McClusky, H. Y., Milby, J. B., Switzer, P. K., Williams, V., & Wooten, V. D.
- Affiliations
- University of Alabama at Birmingham (US)
- Venue
- American Journal of Psychiatry
- Published
- 1991-01-01
- Volume
- 148
- Issue
- 1
- Pages
- 121-126
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W1811457666
- Cited by
- 152
- References
- 34
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 1 · 2023: 2 · 2022: 1 · 2021: 2 · 2020: 2 · 2019: 1 · 2018: 2 · 2017: 2 · 2016: 5 · 2015: 2 · 2014: 5 · 2013: 1 · 2012: 6
- FWCI
- 9.66
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Keywords
- sleep onset insomnia, chronic insomnia, triazolam, behavior therapy, stimulus control, relaxation training, sleep latency, maintenance therapy, medication effects, combination therapy
- MeSH terms
- Adult, Behavior Therapy, Evaluation Studies as Topic, Female, Follow-Up Studies, Humans, Sleep Initiation and Maintenance Disorders, Male, Personality Inventory, Relaxation Therapy, Sleep, Triazolam
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