The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
Late-Life Depression and Microstructural Abnormalities in Dorsolateral Prefrontal Cortex White Matter
Abstract
OBJECTIVE: The purpose of this study was to determine whether microstructural abnormalities in the white matter of the dorsolateral prefrontal cortex are associated with late-life depression. METHOD: Seventeen elderly depressed subjects were compared with 16 elderly subjects who were not depressed. Diffusion tensor imaging was used to measure the fractional anisotropy of the white matter in the dorsolateral prefrontal cortex's superior and middle frontal gyri bilaterally and in the left occipital lobe as a control region. The authors compared results between groups while controlling for age, sex, and comorbid medical disorders. RESULTS: Even after controlling for age, sex, hypertension, and heart disease, the authors found significantly lower fractional anisotropy values in the right superior frontal gyrus white matter of depressed patients than comparison subjects. CONCLUSIONS: Microstructural changes in the white matter of the right superior frontal gyrus are associated with late-life depression. Further work is needed to determine how these changes contribute to depression outcomes.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Previous studies using diffusion imaging have demonstrated reduced fractional anisotropy in ACC and prefrontal white matter generally in depressed subjects (Taylor et al. 2004; Bae et al. 2006; Nobuhara et al. 2006); future studies using diffusion tractography should test the integrity of the specific tracts identified here in patients with mood disorders.”
From Anatomical connectivity of the subgenual cingulate region targeted with deep brain stimulation for treatment-resistant depression (2008) · cites this paper as Taylor et al. 2004
Citations
Cites
The CES-D Scale: A Self-Report Depression Scale for Research in the General Population
Radloff, L. S. (1977) · Applied Psychological Measurement · doi:10.1177/014662167700100306 · Cited by 53,267
A new depression scale designed to be sensitive to change
Montgomery, S. A., & Åsberg, M. (1979) · British Journal of Psychiatry · doi:10.1192/bjp.134.4.382 · Cited by 13,962
Robins, L. N. (1981) · Archives of General Psychiatry · doi:10.1001/archpsyc.1981.01780290015001 · Cited by 5,219
Basser, P. J., & Pierpaoli, C. (1996) · Journal of Magnetic Resonance, Series B · doi:10.1006/jmrb.1996.0086 · Cited by 4,306
Mayberg, H. S., Liotti, M., Brannan, S. K., McGinnis, S., Mahurin, R. K., Jerabek, P. A., Silva, J. A., Tekell, J. L., Martin, C. C., Lancaster, J. L., et al. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.5.675 · Cited by 2,416
Limbic-cortical dysregulation: a proposed model of depression
(1997) · The Journal of Neuropsychiatry and Clinical Neurosciences · doi:10.1176/jnp.9.3.471 · Cited by 1,585
Reduction of Prefrontal Cortex Glucose Metabolism Common to Three Types of Depression
Baxter, L. R. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810030049007 · Cited by 1,320
The NIMH Epidemiologic Catchment Area Program
Regier, D. A. (1984) · Archives of General Psychiatry · doi:10.1001/archpsyc.1984.01790210016003 · Cited by 1,259
Frontal–subcortical neuronal circuits and clinical neuropsychiatry
Tekin, S., & Cummings, J. L. (2002) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(02)00428-2 · Cited by 1,240
Anxiety and affective style: role of prefrontal cortex and amygdala
Davidson, R. J. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01328-2 · Cited by 1,170
MRI-defined vascular depression
(1997) · American Journal of Psychiatry · doi:10.1176/ajp.154.4.497 · Cited by 770
Self-citationNeural circuitry underlying voluntary suppression of sadness
Lévesque, J., Eugène, F., Joanette, Y., Paquette, V., Mensour, B., Beaudoin, G., Leroux, J.-M., Bourgouin, P., & Beauregard, M. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01817-6 · Cited by 689
A simplified method to measure the diffusion tensor from seven MR images
Basser, P. J., & Pierpaoli, C. M. (1998) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910390610 · Cited by 584
Executive Dysfunction and Long-term Outcomes of Geriatric Depression
Alexopoulos, G. S., Meyers, B. S., Young, R. C., Kalayam, B., Kakuma, T., Gabrielle, M., Sirey, J. A., & Hull, J. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.3.285 · Cited by 486
Executive Dysfunction in Geriatric Depression
Lockwood, K. A., Alexopoulos, G. S., & van Gorp, W. G. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.7.1119 · Cited by 378
Magnetic Resonance Imaging of the Caudate Nuclei in Depression: Preliminary Observations
Krishnan, K. R. R. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820070047007 · Cited by 365
Self-citationAlexopoulos, G. S., Kiosses, D. N., Choi, S. J., Murphy, C. F., & Lim, K. O. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.11.1929 · Cited by 307
Conturo, T. E., McKinstry, R. C., Akbudak, E., & Robinson, B. H. (1996) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910350319 · Cited by 293
Cognition and white matter hyperintensities in older depressed patients
Lesser, I. M., Boone, K. B., Mehringer, C. M., Wohl, M. A., Miller, B. L., & Berman, N. (1996) · American Journal of Psychiatry · doi:10.1176/ajp.153.10.1280 · Cited by 283
Prefrontal Dysfunction and Treatment Response in Geriatric Depression
Kalayam, B., & Alexopoulos, G. S. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.8.713 · Cited by 263
Kumar, A., Thomas, A., Lavretsky, H., Yue, K. T. N., Huda, A., Curran, J. G., Venkatraman, T. N., Estanol, L., Mintz, J., Mega, M. S., et al. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.4.630 · Cited by 189
MRI signal hyperintensities in geriatric depression
GREENWALD, B. S., Kramer‐Ginsberg, E., Krishnan, R. R., Ashtari, M., Aupperle, P. M., & Patel, M. C. (1996) · American Journal of Psychiatry · doi:10.1176/ajp.153.9.1212 · Cited by 187
Kumar, A. (2000) · Neuropsychopharmacology · doi:10.1016/s0893-133x(99)00124-4 · Cited by 181
The regional prefrontal syndromes: a theoretical and clinical overview
Duffy, J. D., & Campbell, J. J. (1994) · Journal of Neuropsychiatry · doi:10.1176/jnp.6.4.379 · Cited by 174
Medial orbital frontal lesions in late-onset depression
MacFall, J. R., Payne, M. E., Provenzale, J. E., & Krishnan, K. R. R. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(00)01113-6 · Cited by 163
Self-citationKumar, A., Newberg, A. B., Alavi, A. A., Berlin, J. A., Smith, R., & Reivich, M. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.15.7019 · Cited by 134
Thomas, A. J., Ferrier, I. N., Kalaria, R. N., Woodward, S. A., Ballard, C. G., Oakley, A. E., Perry, R. H., & O'Brien, J. T. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.10.1682 · Cited by 102
Curran, S., Murray, C. M., Beck, M. V., Dougall, N. J., O’Carroll, R. E., Austin, M., Ebmeier, K. P., & Goodwin, G. M. (1993) · The British Journal of Psychiatry · doi:10.1192/bjp.163.2.155 · Cited by 75
Martínez, J. A. (2005) · Medicina Paliativa · Cited by 24
Orientaciones para la sedaciÓn del enfermo terminal
Vidal, A. C., & Olarte, J. M. N. (2001) · Medicina Paliativa · Cited by 24
Muerte encefálica y toma de decisiones en la Unidad de Cuidados Intensivos
Millá, P. M. (2000) · Medicina Intensiva · doi:10.1016/s0210-5691(00)79581-7 · Cited by 17
Flores, L. F. B. (2005) · DS : Derecho y salud · Cited by 12
Theology and biomedical ethics.
McCormick, R. A. (1982) · PubMed · Cited by 12
Lanuza, C. T.-V. (2003) · Dialnet (Universidad de la Rioja) · Cited by 7
La eutanasia y la Iglesia Católica
Gafo, J. (1990) · Dialnet (Universidad de la Rioja) · Cited by 7
Flagged first, then by citations
Cited by
Sorted by citations
Frontocingulate Dysfunction in Depression: Toward Biomarkers of Treatment Response
Pizzagalli, D. A. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2010.166 · Cited by 945
Koolschijn, P. C. M. P., van Haren, N. E. M., Lensvelt‐Mulders, G. J. L. M., Hulshoff Pol, H. E., & Kahn, R. S. (2009) · Human Brain Mapping · doi:10.1002/hbm.20801 · Cited by 902
Anand, A., Li, Y., Wang, Y., Wu, J., Gao, S., Bukhari, L., Mathews, V. P., Kalnin, A., & Lowe, M. J. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.02.021 · Cited by 787
Gliogenesis and Glial Pathology in Depression
Rajkowska, G., & Miguel-Hidalgo, J. J. (2007) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/187152707780619326 · Cited by 625
Johansen-Berg, H., Gutman, D. A., Behrens, T. E. J., Matthews, P. M., Rushworth, M. F. S., Katz, E., Lozano, A. M., & Mayberg, H. S. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhm167 · Cited by 561
Metadata
- Authors
- Taylor, W. D., MacFall, J. R., Payne, M. E., McQuoid, D. R., Provenzale, J. M., Steffens, D. C., & Krishnan, K. R. R.
- Affiliations
- Duke Medical Center (US)
- Venue
- American Journal of Psychiatry
- Published
- 2004-07-01
- Volume
- 161
- Issue
- 7
- Pages
- 1293-1296
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2142902799
- Cited by
- 230
- References
- 35
- Citations by year
- 2026: 1 · 2025: 6 · 2024: 1 · 2023: 4 · 2022: 4 · 2021: 3 · 2020: 5 · 2019: 5 · 2018: 7 · 2017: 7 · 2016: 6 · 2015: 7 · 2014: 15 · 2013: 19 · 2012: 26
- FWCI
- 11.17
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (K234 MH 65939, R01 MH-54846, R01MH054846, K23MH065939, P50MH60451, P50MH060451)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced Neuroimaging Techniques and Applications
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Keywords
- geriatric depression, dorsolateral prefrontal cortex, white matter microstructure, fractional anisotropy, superior frontal gyrus, middle frontal gyrus
- MeSH terms
- Aged, Major Depressive Disorder, Depressive Disorder, Major, Female, Frontal Lobe, Heart Diseases, Humans, Hypertension, Image Processing, Computer-Assisted, Functional Laterality, Male, Middle Aged, Neural Pathways, Occipital Lobe, Psychiatric Status Rating Scales, Comorbidity, Anisotropy, Echo-Planar Imaging, Prefrontal Cortex, Diffusion Magnetic Resonance Imaging
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
