The DOI matches its Crossref record; 265 of the 268 references it cites were found in a registry or an index.
Neurobiology of Aggression and Violence
Open accessAbstract
Acts of violence account for an estimated 1.43 million deaths worldwide annually. While violence can occur in many contexts, individual acts of aggression account for the majority of instances. In some individuals, repetitive acts of aggression are grounded in an underlying neurobiological susceptibility that is just beginning to be understood. The failure of "top-down" control systems in the prefrontal cortex to modulate aggressive acts that are triggered by anger provoking stimuli appears to play an important role. An imbalance between prefrontal regulatory influences and hyper-responsivity of the amygdala and other limbic regions involved in affective evaluation are implicated. Insufficient serotonergic facilitation of "top-down" control, excessive catecholaminergic stimulation, and subcortical imbalances of glutamatergic/gabaminergic systems as well as pathology in neuropeptide systems involved in the regulation of affiliative behavior may contribute to abnormalities in this circuitry. Thus, pharmacological interventions such as mood stabilizers, which dampen limbic irritability, or selective serotonin reuptake inhibitors (SSRIs), which may enhance "top-down" control, as well as psychosocial interventions to develop alternative coping skills and reinforce reflective delays may be therapeutic.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Gene expression in the prefrontal cortex (PFC) has been shown to play a crucial role in the regulation of aggressive behavior [21, 22].”
From Gene expression profiles underlying aggressive behavior in the prefrontal cortex of cattle (2021) · cites this paper as [22]
In the citing paper
“It has been shown that aberrant presenilin expression also plays an important role in Alzheimer’s disease, with behaviors such as agitation and aggression frequently occurring in patients [22, 50].”
From Gene expression profiles underlying aggressive behavior in the prefrontal cortex of cattle (2021) · cites this paper as [22]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Role of genotype in the cycle of violence in maltreated children
Caspi, A., McClay, J., Moffitt, T. E., Mill, J., Martin, J., Craig, I. W., Taylor, A., & Poulton, R. (2002) · Science · doi:10.1126/science.1072290 · Cited by 4,842
Oxytocin increases trust in humans
Kosfeld, M., Heinrichs, M., Zak, P. J., Fischbacher, U., & Fehr, E. (2005) · Nature · doi:10.1038/nature03701 · Cited by 3,690
Dodge, K. A., & Coie, J. D. (1987) · Journal of Personality and Social Psychology · doi:10.1037//0022-3514.53.6.1146 · Cited by 2,546
Allelic Variation of Human Serotonin Transporter Gene Expression
Heils, A., Teufel, A., Petri, S., Stöber, G., Riederer, P., Bengel, D., & Lesch, K. P. (1996) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1996.66062621.x · Cited by 2,221
Emotion, attention, and the startle reflex
Lang, P. J., Bradley, M. M., & Cuthbert, B. N. (1990) · Psychological Review · doi:10.1037/0033-295x.97.3.377 · Cited by 2,205
Serious mental disorder in 23 000 prisoners: a systematic review of 62 surveys
Fazel, S., & Danesh, J. (2002) · The Lancet · doi:10.1016/s0140-6736(02)07740-1 · Cited by 2,201
Social Information-Processing Mechanisms in Reactive and Proactive Aggression
Crick, N. R., & Dodge, K. A. (1996) · Child Development · doi:10.2307/1131875 · Cited by 2,095
Pezawas, L., Meyer-Lindenberg, A., Drabant, E. M., Verchinski, B. A., Munoz, K. E., Kolachana, B. S., Egan, M. F., Mattay, V. S., Hariri, A. R., & Weinberger, D. R. (2005) · Nature Neuroscience · doi:10.1038/nn1463 · Cited by 1,980
The Amygdaloid Complex: Anatomy and Physiology
SAH, P., FABER, E. S. L., LOPEZ DE ARMENTIA, M., & POWER, J. (2003) · Physiological Reviews · doi:10.1152/physrev.00002.2003 · Cited by 1,745
Why Does Social Exclusion Hurt? The Relationship Between Social and Physical Pain.
MacDonald, G., & Leary, M. R. (2005) · Psychological Bulletin · doi:10.1037/0033-2909.131.2.202 · Cited by 1,712
Research works printed but not linked: 10
- World Health Organization, 2007, Third Milestones of a Global Campaign for Violence Prevention Report 2007: Scaling Up
- Swann AC, 2003, J Clin Psychiatry, 64, 26
- New AS, 2006, Soc Biol Psychiatry, 59, 47s
- Koenigsberg HW, 2007, Biol Psychiatry, 61, 104s
- Koenigsberg HW, 2007, Biol Psychiatry, 61, 200
- Siever L, 2006, Biol Psychiatry, 59, 100s
- Siever LJ, 1992, Neuropsychopharmacology, 6, 165
- Symons FJ, 2004, Ment Retard Dev Disabli Res Rev, 10, 13
- Sher L, Understanding Non-Suicidal Self-Injury: Current Science and Practice
- Hermans EJ, 2007, Ramsey NF
Cited by
Sorted by citations
Items 101–200 of 983
Lithium levels in the public drinking water supply and risk of suicide: A pilot study
Liaugaudaitė, V., Mickuvienė, N., Raškauskienė, N., Naginienė, R., & Sher, L. (2017) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2017.03.009 · Cited by 79
The neurobiology of human social behaviour: an important but neglected topic
Young, S. N. (2008) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0836 · Cited by 72
Hamazaki, K., Hamazaki, T., & Inadera, H. (2012) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2012.04.012 · Cited by 75
Eye Tracking Unconscious Face-to-Face Confrontations
Terburg, D., Hooiveld, N., Aarts, H., Kenemans, J. L., & van Honk, J. (2011) · Psychological Science · doi:10.1177/0956797611398492 · Cited by 74
Drugs related to monoamine oxidase activity
Fišar, Z. (2016) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2016.02.012 · Cited by 73
Walker, K., Bowen, E., & Brown, S. (2012) · Aggression and Violent Behavior · doi:10.1016/j.avb.2012.11.021 · Cited by 80
Borderline Personality Disorder (BPD): In the Midst of Vulnerability, Chaos, and Awe
Kulacaoğlu, F., & Köse, S. (2018) · Brain Sciences · doi:10.3390/brainsci8110201 · Cited by 71
A Meta-Analysis of the Val158Met COMT Polymorphism and Violent Behavior in Schizophrenia
Singh, J. P., Volavka, J., Czobor, P., & Dorn, R. A. V. (2012) · PLoS ONE · doi:10.1371/journal.pone.0043423 · Cited by 70
Trends in Psychiatry and Psychotherapy
(2020) · Trends in Psychiatry and Psychotherapy · doi:10.47626/2237-6089 · Cited by 70
Impulse control and criminal responsibility: Lessons from neuroscience
Penney, S. (2012) · International Journal of Law and Psychiatry · doi:10.1016/j.ijlp.2011.12.004 · Cited by 70
Soloff, P. H., White, R. T., Omari, A. A., Ramaseshan, K. S., & Diwadkar, V. A. (2015) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2015.04.006 · Cited by 73
Association of dopamine‐ and serotonin‐related genes with canine aggression
Våge, J., Wade, C., Biagi, T., Fatjó, J., Amat, M., Lindblad-Toh, K., & Lingaas, F. (2010) · Genes, Brain and Behavior · doi:10.1111/j.1601-183x.2010.00568.x · Cited by 65
Mikics, É., Guirado, R., Umemori, J., Tóth, M., Bíró, L., Miskolczi, C., Balázsfi, D., Zelena, D., Ċastrén, E., Haller, J., et al. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2017.142 · Cited by 73
Pérez-Rodríguez, M. M., Weinstein, S. R., New, A. S., Bevilacqua, L. M., Yuan, Q., Zhou, Z., Hodgkinson, C. A., Goodman, M. S., Koenigsberg, H. W., Goldman, D. A., et al. (2010) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2010.03.014 · Cited by 70
Self-citationBooij, L., Tremblay, R. E., Leyton, M., Séguin, J. R., Vitaro, F., Gravel, P., Perreau-Linck, E., Lévesque, M. L., Durand, F., Dikšić, M., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0011255 · Cited by 66
Alcorn, J. L., Gowin, J. L., Green, C. E., Swann, A. C., Moeller, F. G., & Lane, S. D. (2013) · Journal of Neuropsychiatry · doi:10.1176/appi.neuropsych.12030060 · Cited by 65
Bíró, L., Tóth, M., Sipos, E., Bruzsik, B., Tulogdi, Á., Bendahan, S., Sandi, C., & Haller, J. (2016) · Brain Structure and Function · doi:10.1007/s00429-016-1312-z · Cited by 68
Understanding the neuropsychiatric consequences associated with significant traumatic brain injury
Bhalerao, S., Geurtjens, C., Thomas, G. R., Kitamura, C., Zhou, C., & Marlborough, M. A. (2013) · Brain Injury · doi:10.3109/02699052.2013.793396 · Cited by 64
RBFOX1, encoding a splicing regulator, is a candidate gene for aggressive behavior
Fernàndez‐Castillo, N., Gan, G., van Donkelaar, M. M. J., Vaht, M., Weber, H., Retz, W., Meyer‐Lindenberg, A., Franke, B., Harro, J., Reif, A., et al. (2017) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2017.11.012 · Cited by 65
Sex differences in orbitofrontal connectivity in male and female veterans with TBI
McGlade, E., Rogowska, J., & Yurgelun-Todd, D. (2015) · Brain Imaging and Behavior · doi:10.1007/s11682-015-9379-3 · Cited by 63
Costanza, A., Rothen, S., Achab, S., Thorens, G., Baertschi, M., Weber, K., Canuto, A., Richard-Lepouriel, H., Perroud, N. A., & ZULLINO, D. F. (2020) · International Journal of Mental Health and Addiction · doi:10.1007/s11469-020-00259-3 · Cited by 65
Adult Emergence Agitation: A Veteran-Focused Narrative Review
Tolly, B., Waly, A. A., Peterson, G., Erbes, C. R., Prielipp, R. C., & Apostolidou, I. (2020) · Anesthesia & Analgesia · doi:10.1213/ane.0000000000005211 · Cited by 63
Comai, S., Bertazzo, A., Vachon, J., Daigle, M. S., Toupin, J., Côté, G., Turecki, G., & Gobbi, G. (2016) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2016.04.012 · Cited by 63
Hawes, S. W., Perlman, S. B., Byrd, A. L., Raine, A., Loeber, R., & Pardini, D. A. (2015) · Journal of Abnormal Psychology · doi:10.1037/abn0000129 · Cited by 66
Anxiety and aggression in adolescents with autism spectrum disorders attending mainstream schools
Ambler, P. G., Eidels, A., & Gregory, C. (2015) · Research in Autism · doi:10.1016/j.rasd.2015.07.005 · Cited by 75
The rodent accessory olfactory system
Mucignat‐Caretta, C. (2010) · Journal of Comparative Physiology A · doi:10.1007/s00359-010-0555-z · Cited by 62
Barzilay, R., Lobel, T. E., Krivoy, A., Shlosberg, D., Weizman, A., & Katz, N. (2015) · European Psychiatry · doi:10.1016/j.eurpsy.2015.09.461 · Cited by 61
Coppens, C. M., Siripornmongcolchai, T., Wibrand, K., Alme, M. N., Buwalda, B., de Boer, S. F., Koolhaas, J. M., & Bramham, C. R. (2011) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2011.00072 · Cited by 61
Meloy, J. R. (2018) · Journal of Personality Assessment · doi:10.1080/00223891.2018.1481077 · Cited by 61
Corvo, K., & Johnson, P. (2012) · Aggression and Violent Behavior · doi:10.1016/j.avb.2012.11.017 · Cited by 62
Cortical control of aggression: GABA signalling in the anterior cingulate cortex
Jager, A., Amiri, H., Bielczyk, N., van Heukelum, S., Heerschap, A., Aschrafi, A., Poelmans, G., Buitelaar, J. K., Kozicz, T., & Glennon, J. C. (2020) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2017.12.007 · Cited by 60
Altered cerebellar-amygdala connectivity in violent offenders: A resting-state fMRI study
Leutgeb, V., Wabnegger, A., Leitner, M., Zussner, T., Scharmüller, W., Klug, D., & Schienle, A. (2015) · Neuroscience Letters · doi:10.1016/j.neulet.2015.10.063 · Cited by 60
Endogenous testosterone and cortisol modulate neural responses during induced anger control
Denson, T. F., Ronay, R., von Hippel, W., & Schira, M. M. (2012) · Social Neuroscience · doi:10.1080/17470919.2012.655425 · Cited by 65
Pottoo, F., Javed, M. N., Barkat, M., Alam, M. S., Nowshehri, J. A., Alshayban, D., & Ansari, M. (2019) · Current Neuropharmacology · doi:10.2174/1570159x16666180628164432 · Cited by 42
Neural networks of aggression: ALE meta-analyses on trait and elicited aggression
Wong, T. Y., Sid, A., Wensing, T., Eickhoff, S. B., Habel, U., Gur, R. C., & Nickl‐Jockschat, T. (2018) · Brain Structure and Function · doi:10.1007/s00429-018-1765-3 · Cited by 65
Tao, S., Li, J., Zhang, M., Zheng, P., Lau, E. Y. H., Sun, J., & Zhu, Y. (2021) · Mindfulness · doi:10.1007/s12671-020-01570-9 · Cited by 71
Bobadilla, L., Wampler, M., & Taylor, J. E. (2012) · Journal of Social and Clinical Psychology · doi:10.1521/jscp.2012.31.5.458 · Cited by 66
Smeijers, D., Rinck, M., Bulten, E., van den Heuvel, T., & Verkes, R. (2017) · Aggressive Behavior · doi:10.1002/ab.21697 · Cited by 62
Regional grey matter volume reduction in adolescents engaging in non-suicidal self-injury
Ando, A., Reichl, C., Scheu, F., Bykova, A., Parzer, P., Resch, F., Brunner, R., & Kaess, M. (2018) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2018.08.005 · Cited by 58
Deconstructing Anger in the Human Brain
Gilam, G., & Hendler, T. (2015) · Current topics in behavioral neurosciences · doi:10.1007/7854_2015_408 · Cited by 57
da Cunha‐Bang, S., Hjordt, L. V., Perfalk, E., Beliveau, V., Bock, C., Lehel, S., Thomsen, C. E., Sestoft, D. M., Svarer, C., & Knudsen, G. M. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2016.02.030 · Cited by 58
Sex differences in the neural correlates of aggression
Repple, J., Habel, U., Wagels, L., Pawliczek, C. M., Schneider, F. W., & Kohn, N. (2018) · Brain Structure and Function · doi:10.1007/s00429-018-1739-5 · Cited by 58
Dugre, J. R., Dumais, A., Dellazizzo, L., & Potvin, S. (2019) · Psychological Medicine · doi:10.1017/s0033291719001272 · Cited by 61
10-Year Outcome of Suicidal Behavior in Borderline Personality Disorder
Soloff, P. H., & Chiappetta, L. (2018) · Journal of Personality Disorders · doi:10.1521/pedi_2018_32_332 · Cited by 56
Stahl, S. M. (2014) · CNS Spectrums · doi:10.1017/s1092852914000522 · Cited by 56
Prefrontal cortex lesions and MAO-A modulate aggression in penetrating traumatic brain injury
Pardini, M., Krüeger, F., Hodgkinson, C. A., Raymont, V., Ferrier, C., Goldman, D. A., Strenziok, M., Guida, S., & Grafman, J. H. (2011) · Neurology · doi:10.1212/wnl.0b013e318211c33e · Cited by 55
Neuroimaging correlates of aggression in schizophrenia: an update
Hoptman, M. J., & Antonius, D. (2010) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e328342c8e0 · Cited by 56
Baum, M. L. (2011) · Neuroethics · doi:10.1007/s12152-011-9108-6 · Cited by 63
Darmedru, C., Demily, C., & Nicolas Franck, B. (2017) · Psychiatry Research · doi:10.1016/j.psychres.2016.12.062 · Cited by 55
CSF and plasma testosterone in attempted suicide
Stefánsson, J. G., Chatzittofis, A., Nordström, P., Arver, S., Åsberg, M., & Jokinen, J. (2016) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2016.08.009 · Cited by 54
Traditional Masculinity and Aggression in Adolescence: Its Relationship with Emotional Processes
Malonda-Vidal, E., García, P. S., Llorca, A., Muñoz‐Navarro, R., & Mestre-Escrivá, V. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18189802 · Cited by 54
Infant malnutrition predicts conduct problems in adolescents
Galler, J. R., Bryce, C. P., Waber, D. P., Hock, R. S., Harrison, R. H., Eaglesfield, G. D., & Fitzmaurice, G. M. (2012) · Nutritional Neuroscience · doi:10.1179/1476830512y.0000000012 · Cited by 54
Schizophrenia and impulsive aggression: A heuristic inquiry with forensic and clinical implications
Felthous, A. R. (2008) · Behavioral Sciences & the Law · doi:10.1002/bsl.846 · Cited by 54
Discovery of biochemical biomarkers for aggression: A role for metabolomics in psychiatry
Hagenbeek, F. A., Kluft, C., Hankemeier, T., Bartels, M., Draisma, H. H. M., Middeldorp, C. M., Berger, R., Noto, A., Lussu, M., Pool, R., et al. (2016) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32435 · Cited by 54
Вячеславовна, Г. А., Svirin, E. P., Pavlov, D., Cespuglio, R., Proshin, A. T., Schroeter, C. A., Lesch, K., & Strekalova, T. V. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24020915 · Cited by 54
Violent and criminal manifestations in dementia patients
Cipriani, G., Lucetti, C., Danti, S., Carlesi, C., & Nuti, A. (2015) · Geriatrics and gerontology international/Geriatrics & gerontology international · doi:10.1111/ggi.12608 · Cited by 54
Dumais, A., Potvin, S., Joyal, C. C., Allaire, J.-F., Stip, É., LESAGE, A. D., Gobbi, G., & Côté, G. (2011) · Schizophrenia Research · doi:10.1016/j.schres.2011.02.024 · Cited by 52
Borderline personality disorder and rTMS: A pilot trial
Cailhol, L., Roussignol, B., Klein, R., Bousquet, B., Simonetta‐Moreau, M., Schmitt, L., Thalamas, C., Tap, G., & Birmes, P. J. (2014) · Psychiatry Research · doi:10.1016/j.psychres.2014.01.030 · Cited by 52
Religion and Psychiatry: Beyond Boundaries
Verhagen, P. J. (2010) · Cited by 52
Nanda, P., Tandon, N., Mathew, I. T., Padmanabhan, J. L., Clementz, B. A., Pearlson, G. D., Sweeney, J. A., Tamminga, C. A., & Keshavan, M. S. (2015) · Schizophrenia Research · doi:10.1016/j.schres.2015.11.030 · Cited by 53
Hecht, L. K., & Latzman, R. D. (2017) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803395.2017.1314450 · Cited by 54
Aggression‐related brain function assessed with the Point Subtraction Aggression Paradigm in fMRI
Skibsted, A. P., da Cunha‐Bang, S., Carré, J. M., Hansen, A. E., Beliveau, V., Knudsen, G. M., & Fisher, P. M. (2017) · Aggressive Behavior · doi:10.1002/ab.21718 · Cited by 51
Brain morphology of childhood aggressive behavior: A multi-informant study in school-age children
Thijssen, S., Ringoot, A. P., Wildeboer, A., Bakermans‐Kranenburg, M. J., Marroun, H. E., Albert Hofman, D., Jaddoe, V. W. V., Verhulst, F. C., Tiemeier, H. W., van IJzendoorn, M. H., et al. (2015) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-015-0344-9 · Cited by 53
Animal Abuse as an Indicator of Domestic Violence: One Health, One Welfare Approach
Mota‐Rojas, D., Monsalve, S., Lezama-García, K., Mora‐Medina, P., Domínguez-Oliva, A., Ramírez-Necoechea, R., & Garcia, R. D. C. M. (2022) · Animals · doi:10.3390/ani12080977 · Cited by 65
Soloff, P. H., Abraham, K., Burgess, A., Ramaseshan, K. S., Chowdury, A., & Diwadkar, V. A. (2016) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2016.12.009 · Cited by 54
Peck, Y., CLOUGH, A. R., Culshaw, P. N., & Liddell, M. J. (2019) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2019.03.019 · Cited by 50
Moeller, S. J., Froböse, M. I., Konova, A. B., Misyrlis, M., Parvaz, M. A., Goldstein, R. Z., & Alia‐Klein, N. (2014) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2014.07.016 · Cited by 51
Dorsal/ventral parcellation of the amygdala: Relevance to impulsivity and aggression
Gopal, A. A., Clark, E. L., Allgair, A., D’Amato, C., Furman, M., Gansler, D. A., & Fulwiler, C. (2013) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2012.10.010 · Cited by 53
Crocker, A. G., Prokić, A., Morin, D., & Reyes, A.-T. (2013) · Journal of Intellectual Disability Research · doi:10.1111/jir.12080 · Cited by 47
Is there a shared neurobiology between aggression and Internet addiction disorder?
Hahn, C., & Kim, D. (2014) · Journal of Behavioral Addictions · doi:10.1556/jba.3.2014.1.2 · Cited by 47
Orbitofrontal cortical thinning and aggression in mild traumatic brain injury patients
Epstein, D. J., Legarreta, M., Bueler, E., King, J., McGlade, E., & Yurgelun‐Todd, D. (2016) · Brain and Behavior · doi:10.1002/brb3.581 · Cited by 47
Mumford, E. A., Taylor, B. G., Berg, M. T., Liu, W., & Miesfeld, N. (2018) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2018.10.016 · Cited by 47
Вячеславовна, Г. А., Pavlov, D., Anthony, D. C., Ponomarev, E. D., Sambon, M., Proshin, A. T., Shafarevich, I., Babaevskaya, D., Lesch, K., Bettendorff, L., et al. (2019) · Neuropharmacology · doi:10.1016/j.neuropharm.2019.02.025 · Cited by 47
Kaltsouni, E., Fisher, P. M., Dubol, M., Hustad, S., Lanzenberger, R. R., Frøkjær, V. G., Wikström, J., Comasco, E., & Poromaa, I. S. (2021) · Neuropsychopharmacology · doi:10.1038/s41386-021-01010-9 · Cited by 46
Molero‐Chamizo, A., Riquel, R. M., Moriana, J. A., Nitsche, M. A., & Urbina, G. N. R. (2018) · Neuroscience · doi:10.1016/j.neuroscience.2018.11.018 · Cited by 53
Yan, J., Monaco, H., & Xavier, J. B. (2019) · Annual Review of Microbiology · doi:10.1146/annurev-micro-020518-120033 · Cited by 43
Dystrophic Serotonin Axons in Postmortem Brains from Young Autism Patients
Azmitia, E. C., Singh, J. S., Hou, X. P., & Węgiel, J. (2011) · The Anatomical Record · doi:10.1002/ar.21243 · Cited by 46
Madsen, K., Erritzoe, D., Mortensen, E. L., Gade, A., Madsen, J., Baaré, W., Knudsen, G. M., & Hasselbalch, S. G. (2011) · Psychopharmacology · doi:10.1007/s00213-010-1926-4 · Cited by 45
Aebi, M., van Donkelaar, M. M. J., Poelmans, G., Buitelaar, J. K., Sonuga-Barke, E. J. S., Stringaris, A. K., Faraone, S. V., Franke, B., Steinhausen, H., & van Hulzen, K. J. E. (2015) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32346 · Cited by 47
Mentis, A. A., Dardiotis, E., Katsouni, E., & Chrousos, G. P. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01257-2 · Cited by 60
Walling, S. M., Meehan, J. C., Marshall, A. D., Holtzworth‐Munroe, A., & Taft, C. T. (2011) · Journal of Marital and Family Therapy · doi:10.1111/j.1752-0606.2011.00226.x · Cited by 45
High prevalence of brain pathology in violent prisoners: a qualitative CT and MRI scan study
Schiltz, K., Witzel, J. G., Bausch-Hölterhoff, J., & Bogerts, B. (2013) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-013-0403-6 · Cited by 48
Morandotti, N., Dima, D., Jogia, J., Frangou, S., Sala, M., Vidovich, G. Z. D., Lazzaretti, M., Gambini, F., Marraffini, E., d'Allio, G., et al. (2013) · Psychiatry Research · doi:10.1016/j.pscychresns.2013.02.002 · Cited by 49
Characterization of 5-HT1A/1B−/− mice: An animal model sensitive to anxiolytic treatments
Guilloux, J., David, D. J. P., Xia, L., Nguyen, H. T., Rainer, Q., Guiard, B. P., Repérant, C., Deltheil, T., Tóth, M., Hen, R., et al. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.02.009 · Cited by 51
Mence, M., Hawes, D. J., Wedgwood, L., Morgan, S. S. J., Barnett, B. E. W., Kohlhoff, J. R., & Hunt, C. J. (2014) · Journal of Family Psychology · doi:10.1037/a0035352 · Cited by 44
Fung, L. K., Libove, R. A., Phillips, J. M., Haddad, F., & Hardan, A. Y. (2014) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-014-2144-4 · Cited by 47
On thwarted goals and displaced aggression: A compensatory competence model
Leander, N. P., & Chartrand, T. L. (2017) · Journal of Experimental Social Psychology · doi:10.1016/j.jesp.2017.04.010 · Cited by 46
Persistency of Cannabis Use Predicts Violence following Acute Psychiatric Discharge
Dugre, J. R., Dellazizzo, L., Giguère, C., Potvin, S., & Dumais, A. (2017) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2017.00176 · Cited by 43
Locci, A., & Pinna, G. (2018) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2018.12.014 · Cited by 42
How reliable are amygdala findings in psychopathy? A systematic review of MRI studies
Deming, P., Heilicher, M. O., & Koenigs, M. R. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104875 · Cited by 53
Gillespie, S. M., Brzozowski, A., & Mitchell, I. (2017) · Psychology Crime and Law · doi:10.1080/1068316x.2017.1414816 · Cited by 52
Thomas, L., & Egan, V. (2022) · Aggression and Violent Behavior · doi:10.1016/j.avb.2022.101750 · Cited by 45
Effects of Oxytocin on Women's Aggression Depend on State Anxiety
Campbell, A. C., & Hausmann, M. (2013) · Aggressive Behavior · doi:10.1002/ab.21478 · Cited by 42
Godar, S. C., Bortolato, M., Castelli, M. P., Casti, A., Casu, A., Chen, K. Y., Ennas, M. G., Tambaro, S., & Shih, J. C. (2014) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2014.04.014 · Cited by 44
Manchia, M., & Fanos, V. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.03.024 · Cited by 42
Neuroendocrine underpinning of social recognition in males and females
Aspesi, D., & Choleris, E. (2022) · Journal of Neuroendocrinology · doi:10.1111/jne.13070 · Cited by 41
Nikolic, M., Pezzoli, P., Jaworska, N., & Seto, M. C. (2022) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2022.110596 · Cited by 41
Conway, C., Keenan‐Miller, D., Hammen, C. L., Lind, P. A., Najman, J. M., & Brennan, P. A. (2012) · Journal of Clinical Child & Adolescent Psychology · doi:10.1080/15374416.2012.632351 · Cited by 44
Gender differences in aggression of borderline personality disorder
Mancke, F., Bertsch, K., & Herpertz, S. C. (2015) · Borderline Personality Disorder and Emotion Dysregulation · doi:10.1186/s40479-015-0028-7 · Cited by 41
Are batterers different from other criminals? An fMRI study
Bueso‐Izquierdo, N., Verdejo‐Román, J., Contreras‐Rodríguez, O., Carmona-Perera, M., Pérez-Garcı́a, M., & Hidalgo-Ruzzante, N. A. (2016) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsw020 · Cited by 41
Metadata
- Authors
- Siever, L. J.
- Affiliations
- Icahn School of Medicine at Mount Sinai (US)
- Corresponding author
- Siever, Larry J.
- Venue
- American Journal of Psychiatry
- Published
- 2008-04
- Volume
- 165
- Issue
- 4
- Pages
- 429-442
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- PMC
- PMC4176893
- OpenAlex
- W2143884902
- Cited by
- 984
- References
- 268
- Citations by year
- 2026: 33 · 2025: 38 · 2024: 45 · 2023: 55 · 2022: 53 · 2021: 54 · 2020: 46 · 2019: 56 · 2018: 60 · 2017: 66 · 2016: 70 · 2015: 69 · 2014: 53 · 2013: 56 · 2012: 56
- FWCI
- 9.85
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- U.S. Department of Veterans Affairs
- National Institutes of Health (MO1-RR-00071)
- National Institute of Mental Health (R01MH063875, MO1-RR-00071, MH 56140, MH-63875, R01MH056140)
- National Center for Research Resources (MO1RR00071, M01RR000071, M01-RR-00071)
- NIH Clinical Center
- Topics
- Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- aggression, violence, neurobiology of aggression, prefrontal cortex, top-down control, amygdala, limbic system, serotonergic system, catecholaminergic system, neuropeptides, affiliative behavior, mood stabilizers, selective serotonin reuptake inhibitors, psychosocial interventions, coping strategies
- MeSH terms
- Aggression, Amygdala, Brain, Cognition Disorders, Disease Susceptibility, Kindling, Neurologic, Limbic System, Models, Neurological, Models, Psychological, Terminology as Topic, Violence, Prefrontal Cortex, Neurotransmitter Agents
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
