The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
All-Cause Mortality in Women With Severe Postpartum Psychiatric Disorders
Open accessAbstract
OBJECTIVE: The postpartum period is associated with a high risk of psychiatric episodes. The authors studied mortality in women with first-onset severe psychiatric disorders following childbirth and compared their mortality rates with those in women from the background population including other female psychiatric patients (mothers and childless women). METHOD: In a register-based cohort study with linked information from Danish population registers, the authors identified women with first psychiatric inpatient or outpatient contacts 0-3 months postpartum. The main outcome measure was mortality rate ratios (MRRs): deaths from natural causes (diseases and medical conditions) or unnatural causes (suicides, accidents, and homicides). The cohort included 1,545,857 women representing 68,473,423 person-years at risk. RESULTS: In total, 2,699 women had first-onset psychiatric disorders 0-3 months postpartum, and 96 of these died during follow-up. Women with postpartum psychiatric disorders had a higher MRR (3.74; 95% CI=3.06-4.57) than non-postpartum-onset mothers (MRR=2.73; 95% CI=2.67-2.79) when compared with mothers with no psychiatric history. However, childless women with psychiatric diagnoses had the highest MRR (6.15; 95% CI=5.94-6.38). Unnatural cause of death represented 40.6% of fatalities among women with postpartum psychiatric disorders, and within the first year after diagnosis, suicide risk was drastically increased (MRR=289.42; 95% CI=144.02-581.62) when compared with mothers with no psychiatric history. CONCLUSIONS: Women with severe postpartum psychiatric disorders had increased MRRs compared with mothers without psychiatric diagnoses, and the first year after diagnosis represents a time of particularly high relative risk for suicide in this vulnerable group.
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Self-citation
Metadata
- Authors
- Johannsen, B. M. W., Larsen, J. T., Laursen, T. M., Bergink, V., Meltzer-Brody, S., & Munk-Olsen, T.
- Affiliations
- University of North Carolina at Chapel Hill (US)
- From the National Center for Register-Based Research and the Center for Integrated Register-Based Research, Department of Economics and Business Economics, Aarhus University, Aarhus, Denmark; the Department of Psychiatry, Erasmus Medical Center, Rotterdam, the Netherlands; and the Department of Psychiatry, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill.
- ORCID
- Venue
- American Journal of Psychiatry
- Published
- 2016-06-01
- Volume
- 173
- Issue
- 6
- Pages
- 635-642
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- PMC
- PMC5325688
- OpenAlex
- W2292507621
- Cited by
- 110
- References
- 32
- Citations by year
- 2026: 6 · 2025: 13 · 2024: 15 · 2023: 9 · 2022: 11 · 2021: 10 · 2020: 8 · 2019: 11 · 2018: 10 · 2017: 9 · 2016: 8
- FWCI
- 12.56
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (publishedVersion)
- PubMed Central (acceptedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
- Funders
- Lundbeckfonden (R155-2014-1724, R155-2012-11280)
- National Institute of Mental Health (R01MH104468)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Social Sciences › Sociology and Political Science › Homicide, Infanticide, and Child Abuse
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Maternal and fetal healthcare
- Keywords
- postpartum mental disorders, all-cause mortality, suicide risk, postpartum depression, childless women, mothers, mortality rate ratio, unnatural causes of death, postpartum period
- MeSH terms
- Adolescent, Adult, Mental Disorders, Cause of Death, Denmark, Female, Humans, Puerperal Disorders, Registries, Suicide, Survival Analysis, Case-Control Studies, Postpartum Period, Young Adult
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