The DOI matches its Crossref record; 44 of the 44 references it cites were found in a registry or an index.
Cerebellar-Prefrontal Network Connectivity and Negative Symptoms in Schizophrenia
Open accessAbstract
OBJECTIVE: The interpretability of results in psychiatric neuroimaging is significantly limited by an overreliance on correlational relationships. Purely correlational studies cannot alone determine whether behavior-imaging relationships are causal to illness, functionally compensatory processes, or purely epiphenomena. Negative symptoms (e.g., anhedonia, amotivation, and expressive deficits) are refractory to current medications and are among the foremost causes of disability in schizophrenia. The authors used a two-step approach in identifying and then empirically testing a brain network model of schizophrenia symptoms. METHODS: In the first cohort (N=44), a data-driven resting-state functional connectivity analysis was used to identify a network with connectivity that corresponds to negative symptom severity. In the second cohort (N=11), this network connectivity was modulated with 5 days of twice-daily transcranial magnetic stimulation (TMS) to the cerebellar midline. RESULTS: A breakdown of connectivity in a specific dorsolateral prefrontal cortex-to-cerebellum network directly corresponded to negative symptom severity. Restoration of network connectivity with TMS corresponded to amelioration of negative symptoms, showing a statistically significant strong relationship of negative symptom change in response to functional connectivity change. CONCLUSIONS: These results demonstrate that a connectivity breakdown between the cerebellum and the right dorsolateral prefrontal cortex is associated with negative symptom severity and that correction of this breakdown ameliorates negative symptom severity, supporting a novel network hypothesis for medication-refractory negative symptoms and suggesting that network manipulation may establish causal relationships between network markers and clinical phenomena.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“In subjects with schizophrenia, CBM-iTBS can alter brain metabolism and cerebellar-frontal functional connectivity (Basavaraju et al., 2021; Brady et al., 2019; Cho et al., 2012; Halko et al., 2014; Singh et al., 2019), as well as positively impact affective and cognitive symptoms (Basavaraju et al., 2021; Demirtas-Tatlidede et al., 2010; Garg et al., 2016; Shinn et al., 2023; Zhu et al., 2021).”
From A double-blind, randomized, sham-controlled clinical trial of cerebellar intermittent theta burst stimulation for bipolar disorder: Safety, tolerability, mood and cognitive effects (2025) · cites this paper as Brady et al., 2019
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The Positive and Negative Syndrome Scale (PANSS) for schizophrenia.
Kay, S. R., Fiszbein, A., & Opler, L. A. (1987) · Schizophrenia Bulletin · doi:10.1093/schbul/13.2.261 · Cited by 21,378
The organization of the human cerebral cortex estimated by intrinsic functional connectivity
Thomas Yeo, B. T., Krienen, F. M., Sepulcre, J., Sabuncu, M. R., Lashkari, D., Hollinshead, M., Roffman, J. L., Smoller, J. W., Zöllei, L., Polimeni, J. R., et al. (2011) · Journal of Neurophysiology · doi:10.1152/jn.00338.2011 · Cited by 9,182
Power, J. D., Barnes, K. A., Snyder, A. Z., Schlaggar, B. L., & Petersen, S. E. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2011.10.018 · Cited by 7,429
The organization of the human cerebellum estimated by intrinsic functional connectivity
Buckner, R. L., Krienen, F. M., Castellanos, A., Diaz, J. C., & Yeo, B. T. T. (2011) · Journal of Neurophysiology · doi:10.1152/jn.00339.2011 · Cited by 7,304
Functional Network Organization of the Human Brain
Power, J. D., Cohen, A. L., Nelson, S. M., Wig, G. S., Barnes, K. A., Church, J. A., Vogel, A. C., Laumann, T. O., Miezin, F. M., Schlaggar, B. L., et al. (2011) · Neuron · doi:10.1016/j.neuron.2011.09.006 · Cited by 4,124
DPABI: Data Processing & Analysis for (Resting-State) Brain Imaging
Yan, C., Wang, X., Zuo, X., & Zang, Y. (2016) · Neuroinformatics · doi:10.1007/s12021-016-9299-4 · Cited by 3,935
Resting-state connectivity biomarkers define neurophysiological subtypes of depression
Drysdale, A. T., Grosenick, L., Downar, J., Dunlop, K., Mansouri, F., Meng, Y., Fetcho, R. N., Zebley, B., Oathes, D. J., Etkin, A., et al. (2017) · Nature Medicine · doi:10.1038/nm.4246 · Cited by 2,170
Physiologic Dysfunction of Dorsolateral Prefrontal Cortex in Schizophrenia
Weinberger, D. R. (1986) · Archives of General Psychiatry · doi:10.1001/archpsyc.1986.01800020020004 · Cited by 2,025
The Scale for the Assessment of Negative Symptoms (SANS): Conceptual and Theoretical Foundations
Andreasen, N. C. (1989) · The British Journal of Psychiatry · doi:10.1192/s0007125000291496 · Cited by 1,532
Andreasen, N. C., Paradiso, S., & OʼLeary, D. S. (1998) · Schizophrenia Bulletin · doi:10.1093/oxfordjournals.schbul.a033321 · Cited by 1,193
Cited by
Sorted by citations
The Theory and Neuroscience of Cerebellar Cognition
Schmahmann, J. D., Guell, X., Stoodley, C. J., & Halko, M. A. (2019) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-070918-050258 · Cited by 587
Self-citationAssessing the mechanisms of brain plasticity by transcranial magnetic stimulation
Jannati, A., Oberman, L. M., Rotenberg, A., & Pascual‐Leone, Á. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-022-01453-8 · Cited by 326
Regulation of autism-relevant behaviors by cerebellar-prefrontal cortical circuits
Kelly, E., Meng, F., Fujita, H., Morgado, F., Kazemi, Y., Rice, L. C., Ren, C., Escamilla, C. O., Gibson, J. M., Sajadi, S., et al. (2020) · Nature Neuroscience · doi:10.1038/s41593-020-0665-z · Cited by 280
Fujita, H., Kodama, T., & du Lac, S. (2020) · eLife · doi:10.7554/elife.58613 · Cited by 254
The Cerebellar Cognitive Affective/Schmahmann Syndrome: a Task Force Paper
Argyropoulos, G. P. D., van Dun, K., Adamaszek, M., Leggio, M. G., Manto, M. U., Masciullo, M., Molinari, M., Stoodley, C. J., Overwalle, F. V., Ivry, R. B., et al. (2019) · The Cerebellum · doi:10.1007/s12311-019-01068-8 · Cited by 260
Self-citationDopamine Receptor Subtypes, Physiology and Pharmacology: New Ligands and Concepts in Schizophrenia
Martel, J., & McArthur, S. G. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.01003 · Cited by 245
A review of resting-state fMRI and its use to examine psychiatric disorders
Canario, E., Chen, D. Y., & Biswal, B. B. (2021) · Psychoradiology · doi:10.1093/psyrad/kkab003 · Cited by 231
Consensus Paper. Cerebellar Reserve: From Cerebellar Physiology to Cerebellar Disorders
Mitoma, H., Buffo, A., Gelfo, F., Guell, X., Fucà, E., Kakei, S., Lee, J., Manto, M. U., Petrosini, L., Shaikh, A. G., et al. (2019) · The Cerebellum · doi:10.1007/s12311-019-01091-9 · Cited by 171
Self-citationXue, A., Kong, R., Yang, Q., Eldaief, M. C., Angeli, P. A., DiNicola, L. M., Braga, R. M., Buckner, R. L., & Yeo, B. T. T. (2020) · Journal of Neurophysiology · doi:10.1152/jn.00561.2020 · Cited by 151
Reverse-translational identification of a cerebellar satiation network
Low, A. Y. T., Goldstein, N., Gaunt, J. R., Huang, K.-P., Zainolabidin, N., Yip, A. K. K., Carty, J. R. E., Choi, J. Y., Miller, A. M., Ho, H. S. T., et al. (2021) · Nature · doi:10.1038/s41586-021-04143-5 · Cited by 135
Self-citationWhat have we really learned from functional connectivity in clinical populations?
Zhang, J., Kucyi, A., Raya, J., Nielsen, A. N., Nomi, J. S., Damoiseaux, J. S., Greene, D. J., Horovitz, S. G., Uddin, L. Q., & Whitfield, S. (2021) · NeuroImage · doi:10.1016/j.neuroimage.2021.118466 · Cited by 133
Human brain connectivity: Clinical applications for clinical neurophysiology
Hallett, M., de Haan, W., Deco, G., Dengler, R., Iorio, R. D., Galléa, C., Gerloff, C. P., Grefkes, C., Helmich, R. C. G., Kringelbach, M. L., et al. (2020) · Clinical Neurophysiology · doi:10.1016/j.clinph.2020.03.031 · Cited by 118
Ferrarelli, F., & Phillips, M. L. (2021) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2020.20071050 · Cited by 119
Wada, M., Noda, Y., Iwata, Y., Tsugawa, S., Yoshida, K., Tani, H., Hirano, Y., Koike, S., Sasabayashi, D., Katayama, H., et al. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01572-0 · Cited by 113
Compression of Cerebellar Functional Gradients in Schizophrenia
Dong, D., Luo, C., Guell, X., Wang, Y., He, H., Duan, M., Eickhoff, S. B., & Yao, D. (2020) · Schizophrenia Bulletin · doi:10.1093/schbul/sbaa016 · Cited by 109
A Reckoning and Research Agenda for Neuroimaging in Psychiatry
Etkin, A. (2019) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2019.19050521 · Cited by 115
Yoshida, J., Oñate, M., Khatami, L., Vera, J. R., Nadim, F., & Khodakhah, K. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.1535-22.2022 · Cited by 102
Lorentzen, R., Nguyen, T. D., McGirr, A., Hieronymus, F., & Østergaard, S. D. (2022) · Schizophrenia · doi:10.1038/s41537-022-00248-6 · Cited by 104
The Cross-Talk Between the Dopaminergic and the Immune System Involved in Schizophrenia
Vidal, P. M., & Pacheco, R. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00394 · Cited by 92
Functional Territories of Human Dentate Nucleus
Guell, X., D’Mello, A. M., Hubbard, N. A., Romeo, R. R., Gabrieli, J. D. E., Whitfield, S., Schmahmann, J. D., & Anteraper, S. A. (2019) · Cerebral Cortex · doi:10.1093/cercor/bhz247 · Cited by 80
Self-citationPrediction, Psychosis, and the Cerebellum
Moberget, T., & Ivry, R. B. (2019) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2019.06.001 · Cited by 83
Stoodley, C. J., & Tsai, P. T. (2021) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-100120-092143 · Cited by 75
Fabro, L. D., Schmidt, A., Fortea, L., Delvecchio, G., D’Agostino, A., Raduà, J., Borgwardt, S., & Brambilla, P. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.06.020 · Cited by 74
Metoki, A., Wang, Y., & Olson, I. R. (2021) · Cerebral Cortex · doi:10.1093/cercor/bhab260 · Cited by 72
Voineskos, A. N., Hawco, C. S., Neufeld, N. H., Turner, J. A., Ameis, S. H., Anticevic, A., Buchanan, R. W., Cadenhead, K. S., Dazzan, P., Dickie, E. W., et al. (2024) · World Psychiatry · doi:10.1002/wps.21159 · Cited by 81
Self-citationBasavaraju, R., Ithal, D., Thanki, M. V., Ramalingaiah, A. H., Thirthalli, J., Reddy, R. P., Brady, R. O., Halko, M. A., Bolo, N. R., Keshavan, M. S., et al. (2021) · Schizophrenia Research · doi:10.1016/j.schres.2021.10.005 · Cited by 70
Self-citationUnderstanding the effects of serotonin in the brain through its role in the gastrointestinal tract
Shine, J. M., O’Callaghan, C., Walpola, I. C., Wainstein, G., Taylor, N. L., Aru, J., Huebner, B., & John, Y. J. (2022) · Brain · doi:10.1093/brain/awac256 · Cited by 68
rTMS modulates precuneus-hippocampal subregion circuit in patients with subjective cognitive decline
Chen, J., Ma, N., Hu, G., Amdanee, N., Xue, C., Qi, W., Xu, W., Chen, S., Rao, J., Liu, W., et al. (2020) · Aging · doi:10.18632/aging.202313 · Cited by 60
Iraji, A., Faghiri, A., Fu, Z., Rachakonda, S., Kochunov, P., Belger, A., Ford, J. M., McEwen, S. C., Mathalon, D. H., Mueller, B. A., et al. (2021) · Network Neuroscience · doi:10.1162/netn_a_00196 · Cited by 56
Chauhan, P., Garg, S., Tikka, S. K., & Khattri, S. (2021) · The Cerebellum · doi:10.1007/s12311-020-01193-9 · Cited by 57
Investigational and Therapeutic Applications of Transcranial Magnetic Stimulation in Schizophrenia
Mehta, U. M., Naik, S. S., Thanki, M. V., & Thirthalli, J. (2019) · Current Psychiatry Reports · doi:10.1007/s11920-019-1076-2 · Cited by 59
Vanes, L. D., Mouchlianitis, E. D., Patel, K., Barry, E. F., Wong, K., Thomas, M., Szentgyorgyi, T., Joyce, D. W., & Shergill, S. S. (2019) · Scientific Reports · doi:10.1038/s41598-019-51023-0 · Cited by 56
Cao, H., & Cannon, T. D. (2019) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2019.19050480 · Cited by 55
Liu, Y., Xiao, X., Yang, Y., Yao, R., Yang, Q., Zhu, Y., Yang, X., Zhang, S., Shen, L. H., & Jiao, B. (2024) · Alzheimer s & Dementia · doi:10.1002/alz.14049 · Cited by 54
Schmahmann, J. D. (2021) · Handbook of clinical neurology · doi:10.1016/b978-0-12-822290-4.00016-5 · Cited by 50
Self-citationAhmed, A. O., Kirkpatrick, B., Granholm, E., Rowland, L. M., Barker, P. B., Gold, J. M., Buchanan, R. W., Outram, T., Bernardo, M., García‐Portilla, M. P., et al. (2021) · Schizophrenia Bulletin · doi:10.1093/schbul/sbab148 · Cited by 56
Consensus Paper: Cerebellum and Reward
Manto, M. U., Adamaszek, M., Apps, R., Carlson, E. S., Guarque‐Chabrera, J., Heleven, E., Kakei, S., Khodakhah, K., Kuo, S., Lin, C.-Y. R., et al. (2024) · The Cerebellum · doi:10.1007/s12311-024-01702-0 · Cited by 53
Cao, H., Xia, W., Hu, N., Zhang, W., Xiao, Y., Zeng, J., Sweeney, J. A., Lencer, R., Lui, S., & Gong, Q. (2021) · Schizophrenia Bulletin · doi:10.1093/schbul/sbab112 · Cited by 49
The cerebellum and psychological trauma: A systematic review of neuroimaging studies
Blithikioti, C., Nuño, L., Guell, X., Pascual‐Diaz, S., Gual, A., Balcells‐Oliveró, M., & Miquel, L. (2022) · Neurobiology of Stress · doi:10.1016/j.ynstr.2022.100429 · Cited by 49
Hughes, D., Kunitoki, K., Elyounssi, S., Luo, M., Bazer, O. M., Hopkinson, C. E., Dowling, K. F., Doyle, A. E., Dunn, E. C., Eryilmaz, H., et al. (2023) · Nature Neuroscience · doi:10.1038/s41593-023-01321-8 · Cited by 46
Structural and resting state functional connectivity beyond the cortex
Harrison, O. K., Guell, X., Klein-Flügge, M. C., & Barry, R. L. (2021) · NeuroImage · doi:10.1016/j.neuroimage.2021.118379 · Cited by 47
Pushing the Boundaries of Psychiatric Neuroimaging to Ground Diagnosis in Biology
Saggar, M., & Uddin, L. Q. (2019) · eneuro · doi:10.1523/eneuro.0384-19.2019 · Cited by 38
New clues for the role of cerebellum in schizophrenia and the associated cognitive impairment
Faris, P. S., Pischedda, D., Palesi, F., & D'Angelo, E. U. (2024) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2024.1386583 · Cited by 45
Kim, J.-Y., Lee, H. S., & Lee, S. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9123934 · Cited by 41
Dynamic Altered Amplitude of Low-Frequency Fluctuations in Patients With Major Depressive Disorder
Zheng, R., Chen, Y., Jiang, Y. B., Wen, M., Zhou, B., Li, S., Wei, Y., Yang, Z., Wang, C., Cheng, J., et al. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.683610 · Cited by 40
Treatment-resistant schizophrenia: How far have we traveled?
Pandey, A., & Kalita, K. N. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.994425 · Cited by 45
α6-Containing GABAA Receptors: Functional Roles and Therapeutic Potentials
Sieghart, W., Chiou, L., Ernst, M. C., Fabjan, J., Savić, M. M., & Lee, M. T. (2022) · Pharmacological Reviews · doi:10.1124/pharmrev.121.000293 · Cited by 40
The cerebellum regulates fear extinction through thalamo-prefrontal cortex interactions in male mice
Frontera, J. L., Sala, R. W., Georgescu, I. A., Baba Aissa, H., d’Almeida, M. N., Popa, D., & Léna, C. (2023) · Nature Communications · doi:10.1038/s41467-023-36943-w · Cited by 38
Noninvasive neuromodulation of the prefrontal cortex in mental health disorders
Regenold, W. T., Deng, Z., & Lisanby, S. H. (2021) · Neuropsychopharmacology · doi:10.1038/s41386-021-01094-3 · Cited by 38
Cerebellar Functional Dysconnectivity in Drug-Naïve Patients With First-Episode Schizophrenia
Cao, H., Xia, W., Zhang, W., Xiao, Y., Zeng, J., Sweeney, J. A., Gong, Q., & Lui, S. (2022) · Schizophrenia Bulletin · doi:10.1093/schbul/sbac121 · Cited by 40
Cai, X., Wang, Y.-M., Wang, Y., Zhou, H., Huang, J., Wang, Y., Lui, S. S. Y., Møller, A., Hung, K. S. Y., Mak, H. K., et al. (2020) · Schizophrenia Bulletin · doi:10.1093/schbul/sbaa200 · Cited by 37
Zhu, L., Zhang, W., Zhu, Y., Mu, X., Zhang, Q., Wang, Y., Cai, J., & Xie, B. (2021) · Psychiatry Research · doi:10.1016/j.psychres.2021.114204 · Cited by 37
Hua, J. P. Y., Abram, S. V., & Ford, J. M. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.1069488 · Cited by 37
Repetitive Transcranial Magnetic Stimulation for Auditory Verbal Hallucinations in Schizophrenia
Hua, Q., Wang, L., He, K., Sun, J., Xu, W., Zhang, L., Tian, Y., Wang, K., & Ji, G. (2024) · JAMA Network Open · doi:10.1001/jamanetworkopen.2024.44215 · Cited by 40
Neural mapping of anhedonia across psychiatric diagnoses: A transdiagnostic neuroimaging analysis
Schaub, A.-C., Kirschner, M., Schweinfurth, N., Mählmann, L., Kettelhack, C., Engeli, E., Doll, J. P. K., Borgwardt, S., Lang, U. E., Kaiser, S., et al. (2021) · NeuroImage Clinical · doi:10.1016/j.nicl.2021.102825 · Cited by 38
Dopamine D2 receptors in pyramidal neurons in the medial prefrontal cortex regulate social behavior
Chen, H. H., Xiong, X.-X., Jin, S.-Y., He, X., He, X., Yang, J.-M., Gao, T., & Chen, Y. (2023) · Pharmacological Research · doi:10.1016/j.phrs.2023.107042 · Cited by 36
Pan, Z., Xiong, D., Xiao, H., Li, J., Huang, Y., Zhou, J., Chen, J., Li, X., Ning, Y., Wu, F., et al. (2021) · Psychiatry Research · doi:10.1016/j.psychres.2021.113866 · Cited by 35
Psychomotor Slowing in Psychosis and Inhibitory Repetitive Transcranial Magnetic Stimulation
Walther, S., Alexaki, D., Weiss, F., Gama, D. B., Kyrou, A., Nuoffer, M. G., Wüthrich, F., Lefebvre, S., & Nadesalingam, N. (2024) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2024.0026 · Cited by 33
Antonucci, L. A., Penzel, N., Pergola, G., Kambeitz‐Ilankovic, L., Dwyer, D., Kambeitz, J. P., Haas, S. S., Passiatore, R., Fazio, L., Caforio, G., et al. (2019) · Neuropsychopharmacology · doi:10.1038/s41386-019-0532-3 · Cited by 32
Theories and models of negative symptoms in schizophrenia and clinical implications
Chan, R. C. K., Wang, L., & Lui, S. S. Y. (2022) · Nature Reviews Psychology · doi:10.1038/s44159-022-00065-9 · Cited by 35
Effectiveness of Cerebellar Circuitry Modulation in Schizophrenia: A Systematic Review
Escelsior, A., Belvederi Murri, M., Calcagno, P., Cervetti, A., Caruso, R., Croce, E., Grassi, L., & Amore, M. (2019) · Journal of Nervous & Mental Disease · doi:10.1097/nmd.0000000000001064 · Cited by 32
Gan, H., Zhu, J., Zhuo, K., Zhang, J., Tang, Y., Qian, Z., Xiang, Q., Li, X., Zhu, Y., Wang, J., et al. (2021) · Psychiatry Research · doi:10.1016/j.psychres.2021.113876 · Cited by 32
Chen, F.-J., Gu, C., Zhai, N., Duan, H.-F., Zhai, A.-L., & Zhang, X. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00732 · Cited by 32
Xi, Y., Guo, F., Liu, W., Fu, Y., Li, J., Wang, H., Chen, F., Cui, L., Zhu, Y., Li, C., et al. (2021) · Schizophrenia Research · doi:10.1016/j.schres.2021.06.024 · Cited by 35
Cerebellar Structure and Cognitive Ability in Psychosis
Moussa‐Tooks, A. B., Rogers, B. P., Huang, A., Sheffield, J. M., Heckers, S., & Woodward, N. D. (2022) · Biological Psychiatry · doi:10.1016/j.biopsych.2022.03.013 · Cited by 32
Altered cerebral perfusion in bipolar disorder: A pCASL MRI study
Zeng, V., Lizano, P. L., Bolo, N. R., Lutz, O., Brady, R. O., Ivleva, E. I., Dai, W., Clementz, B. A., Tamminga, C. A., Pearlson, G. D., et al. (2020) · Bipolar Disorders · doi:10.1111/bdi.12966 · Cited by 31
Self-citationIraji, A., Faghiri, A., Fu, Z., Kochunov, P. V., Adhikari, B. M., Belger, A., Ford, J. M., McEwen, S. C., Mathalon, D. H., Pearlson, G. D., et al. (2022) · NeuroImage · doi:10.1016/j.neuroimage.2022.119013 · Cited by 31
Ochi, R., Noda, Y., Tsuchimoto, S., Tarumi, R., Honda, S., Matsushita, K., Tsugawa, S., Plitman, E., Masuda, F., Ogyu, K., et al. (2020) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2020.109871 · Cited by 30
The Cerebellum and Cognitive Function: Anatomical Evidence from a Transdiagnostic Sample
Bègue, I., Elandaloussi, Y., Delavari, F., Cao, H., Moussa‐Tooks, A. B., Roser, M. M., Pierrick Coupé, A., Leboyer, M., Kaiser, S., Houenou, J., et al. (2023) · The Cerebellum · doi:10.1007/s12311-023-01645-y · Cited by 29
Self-citationBrain‐based sex differences in schizophrenia: A systematic review of fMRI studies
Salehi, M. A., Zafari, R., Mohammadi, S., Farahani, M. S., Dolatshahi, M., Harandi, H., Poopak, A., & Dager, S. R. (2024) · Human Brain Mapping · doi:10.1002/hbm.26664 · Cited by 31
Nawaz, U., Lee, I., Beermann, A., Eack, S. M., Keshavan, M. S., & Brady, R. O. (2020) · Schizophrenia Bulletin · doi:10.1093/schbul/sbaa088 · Cited by 29
Self-citationBiomarkers Obtained by Transcranial Magnetic Stimulation in Neurodevelopmental Disorders
Jannati, A., Ryan, M. A., Kaye, H. L., Tsuboyama, M., & Rotenberg, A. (2021) · Journal of Clinical Neurophysiology · doi:10.1097/wnp.0000000000000784 · Cited by 29
Linking cerebellar functional gradients to transdiagnostic behavioral dimensions of psychopathology
Dong, D., Guell, X., Genon, S., Wang, Y., Ji, C., Eickhoff, S. B., Yao, D., & Luo, C. (2022) · NeuroImage Clinical · doi:10.1016/j.nicl.2022.103176 · Cited by 29
Kang, N.-O., Chung, S., Lee, S.-H., & Bang, M. (2024) · Schizophrenia · doi:10.1038/s41537-024-00434-8 · Cited by 28
Chen, J., Chen, R., Xue, C., Qi, W., Hu, G., Xu, W., Chen, S., Rao, J., Zhang, F., & Zhang, X. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-210661 · Cited by 27
Wang, X., Zhang, Y., Huang, J., Wang, Y., Niu, Y., Lui, S. S. Y., Hui, L., & Chan, R. C. K. (2023) · Psychological Medicine · doi:10.1017/s0033291723000703 · Cited by 30
Abnormal Effective Connectivity Underlying Auditory Mismatch Negativity Impairments in Schizophrenia
Koshiyama, D., Miyakoshi, M., Joshi, Y. B., Molina, J. L., Tanaka‐Koshiyama, K., Sprock, J., BRAFF, D. L., Swerdlow, N. R., & Light, G. A. (2020) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2020.05.011 · Cited by 28
Anteraper, S. A., Collin, G., Guell, X., Scheinert, T., Molokotos, E. K., Henriksen, M. T., Mesholam‐Gately, R. I., Thermenos, H. W., Seidman, L. J., Keshavan, M. S., et al. (2019) · Schizophrenia Research · doi:10.1016/j.schres.2019.09.006 · Cited by 26
Self-citationWen, N., Chen, L., Miao, X., Zhang, M., Zhang, Y., Liu, J., Xu, Y. Q., Tong, S., Tang, W., Wang, M., et al. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.736094 · Cited by 27
Recent advances in noninvasive brain stimulation for schizophrenia
Brunelin, J., Adam, O., & Mondino, M. (2022) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000809 · Cited by 24
Shi, W., Fan, L., Wang, H., Liu, B., Li, W., Li, J., Cheng, L., Chu, C., Song, M., Jing Sui （Beijing Normal University）， my correct affiliation is beijing normal university, N. Q. U. O. S. A. T., et al. (2022) · Cerebral Cortex · doi:10.1093/cercor/bhac301 · Cited by 24
Zilcha-Mano, S., & Webb, C. A. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.609585 · Cited by 25
Theta Burst Stimulation Protocols for Schizophrenia
Kishi, T., Ikuta, T., Sakuma, K., Hamanaka, S., Nishii, Y., Hatano, M., Kito, S., & Iwata, N. (2024) · JAMA Network Open · doi:10.1001/jamanetworkopen.2024.41159 · Cited by 24
Cerebellar-Cortical Connectivity Is Linked to Social Cognition Trans-Diagnostically
Brady, R. O., Beermann, A., Nye, M., Eack, S. M., Mesholam‐Gately, R. I., Keshavan, M. S., & Lewandowski, K. E. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.573002 · Cited by 26
Self-citationAnteraper, S. A., Guell, X., Collin, G., Qi, Z., Ren, J., Nair, A., Seidman, L. J., Keshavan, M. S., Zhang, T., Tang, Y., et al. (2021) · Schizophrenia Bulletin · doi:10.1093/schbul/sbab038 · Cited by 25
Self-citationXie, Y., Hé, Y., Guan, M., Wang, Z., Zhou, G., Ma, Z., Wang, H., & Yin, H. J. (2022) · Psychiatry Research · doi:10.1016/j.psychres.2022.114393 · Cited by 24
Consider the pons: bridging the gap on sensory prediction abnormalities in schizophrenia
Abram, S. V., Hua, J. P. Y., & Ford, J. M. (2022) · Trends in Neurosciences · doi:10.1016/j.tins.2022.08.008 · Cited by 22
Ciricugno, A., Oldrati, V., Cattaneo, Z., Leggio, M. G., Urgesi, C., & Olivito, G. (2024) · The Cerebellum · doi:10.1007/s12311-023-01652-z · Cited by 24
Safety of rTMS for Schizophrenia: A Systematic Review and Meta-analysis
Blyth, S. H., Bosch, C. C., Raffoul, J. J., Chesley, J., Johnson, B., Borodge, D., Sagarwala, R., Masters, R., Brady, R. O., Vandekar, S., et al. (2024) · Schizophrenia Bulletin · doi:10.1093/schbul/sbae158 · Cited by 25
Self-citationNeurostructural changes in schizophrenia and treatment-resistance: a narrative review
Paul, T., See, J. W., Vijayakumar, V., Njideaka-Kevin, T., Loh, H., Lee, V. J. Q., & Doğrul, B. N. (2024) · Psychoradiology · doi:10.1093/psyrad/kkae015 · Cited by 23
Calcium-binding proteins are altered in the cerebellum in schizophrenia
Vidal-Domènech, F., Alacid, G. R., Pinacho, R., Rodríguez‐Mias, R. A., Vera-Montecinos, A., Monje, A., Ferrer, I., Callado, L. F., Meana, J. J., Villén, J., et al. (2020) · PLoS ONE · doi:10.1371/journal.pone.0230400 · Cited by 22
Voineskos, A. N., Blumberger, D. M., Schifani, C., Hawco, C. S., Dickie, E. W., Rajji, T. K., Mulsant, B. H., Foussias, G., Wang, W., & Daskalakis, Z. J. (2020) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2020.11.011 · Cited by 21
Choi, S. Y., Ha, M., Choi, S., Moon, S., Park, S., Kim, M., & Kwon, J. S. (2023) · Schizophrenia Research · doi:10.1016/j.schres.2022.12.041 · Cited by 22
Wang, S., Sun, H., Hu, G., Xue, C., Qi, W., Rao, J., Zhang, F., Zhang, X., & Chen, J. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.597455 · Cited by 22
Xie, Y., Xi, Y. B., Cui, L., Guan, M., Li, C., Wang, Z. H., Fang, P., & Yin, H. J. (2021) · Psychiatry Research · doi:10.1016/j.psychres.2021.113937 · Cited by 22
Morimoto, C., Uematsu, A., Nakatani, H., Takano, Y., Iwashiro, N., Abe, O., Yamasue, H., Kasai, K., & Koike, S. (2021) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.13277 · Cited by 20
Abnormal Static and Dynamic Functional Network Connectivity in Patients With Presbycusis
Xing, C., Chen, Y., Shang, S., Xǔ, J., Chen, H., Yin, X., Wu, Y., & Zheng, J.-X. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.774901 · Cited by 21
Identification of hub genes and construction of diagnostic nomogram model in schizophrenia
Zhang, C., Dong, N., Xu, S., Ma, H., & Cheng, M. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.1032917 · Cited by 22
Cerebellar-thalamic circuits play a critical role in psychomotor function
Mittal, V. A., Bernard, J. A., & Walther, S. (2020) · Molecular Psychiatry · doi:10.1038/s41380-020-00935-9 · Cited by 21
Schmahmann, J. D. (2022) · The Cerebellum · doi:10.1007/s12311-022-01456-7 · Cited by 21
Self-citation
Metadata
- Authors
- Brady, R. O., Gonsalvez, I., Lee, I., Öngür, D., Seidman, L. J., Schmahmann, J. D., Eack, S. M., Keshavan, M. S., Pascual-Leone, A., & Halko, M. A.
- Affiliations
- Beth Israel Deaconess Medical Center (US)
- From the Department of Psychiatry, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston (Brady, Lee, Seidman, Keshavan); the Schizophrenia and Bipolar Disorders Program, McLean Hospital, Belmont, Mass. (Brady, Öngür); Harvard Medical School, Boston (Brady, Öngür); St. Elizabeth’s Medical Center, Boston (Gonsalvez); the Department of Neurology, Ataxia Unit, Cognitive Behavioral Neurology Unit, and Laboratory for Neuroanatomy and Cerebellar Neurobiology, Massachusetts General Hospital...
- Corresponding author
- Halko, Mark A.
- ORCID
- Venue
- American Journal of Psychiatry
- Published
- 2019-07-01
- Volume
- 176
- Issue
- 7
- Pages
- 512-520
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- PMC
- PMC6760327
- OpenAlex
- W2913822739
- Cited by
- 372
- References
- 44
- Citations by year
- 2026: 27 · 2025: 51 · 2024: 62 · 2023: 53 · 2022: 58 · 2021: 59 · 2020: 47 · 2019: 14
- FWCI
- 25.87
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Sidney R. Baer, Jr. Foundation
- National Institute of Mental Health (K23MH100623, K24MH104449, R01MH111868, R01MH092440)
- National Center for Research Resources (UL1RR025758)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
- Keywords
- schizophrenia, negative symptoms, cerebellum, dorsolateral prefrontal cortex, resting-state functional connectivity, transcranial magnetic stimulation, anhedonia, amotivation
- MeSH terms
- beta-Lactamases, Cerebellum, Female, Humans, Male, Models, Biological, Nerve Net, Psychiatric Status Rating Scales, Schizophrenia, Severity of Illness Index, Prefrontal Cortex, Transcranial Magnetic Stimulation, Young Adult, Neuroimaging
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
