Prevalence and treatment of depression in Parkinson's disease
Abstract
Parkinson's disease (PD) is a progressive neurological condition with debilitating symptoms, and depression is a common comorbid condition of this disease. The authors review existing literature on the prevalence and treatment of depression in PD. Prevalence estimates of depression vary widely, ranging from 7%-76%. This variation is due to inconsistent methodology. Treatment options for depression in PD include medication therapy, electroconvulsive therapy (ECT), and psychotherapy. There are few randomized controlled trials of these treatment options. The authors argue for more systematic and controlled research examining both the prevalence and treatment of depression in PD.
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Concerns regarding unfavorable side effects, including exacerbation of motor problems in patients with complex medication regimes, have been noted.
“concerns regarding unfavorable side effects, including exacerbation of motor problems in patients with complex medication regimes, have been noted (Rabinstein and Shulman, 2000”
From Remote delivery of psychological interventions for Parkinson's disease. (2018) · cites this paper as Veazey et al., 2005
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- Authors
- Veazey, C., Ozlem Erden Aki, S., Cook, K. F., Lai, E. C., & Kunik, M. E.
- Affiliations
- Michael E. DeBakey VA Medical Center (US)
- Received September 12, 2003; revised January 21, 2004; accepted April 5, 2004. From the Houston Center for Quality of Care and Utilization Studies, Health Services Research and Development Service, VA Medical Center, Houston, Texas; the Houston Veterans Affairs Parkinson’s Disease Research, Education, and Clinical Center, Houston, Texas; Baylor College of Medicine, Department of Neurology, Houston, Texas; Baylor College of Medicine, Menninger Department of Psychiatry and Behavioral Sciences, Houston,...
- Baylor College of Medicine (US)
- Venue
- The Journal of Neuropsychiatry and Clinical Neurosciences
- Published
- 2005-08
- Volume
- 17
- Issue
- 3
- Pages
- 310-323
- ISSN
- 0895-0172 (ISSN-L)
- 1545-7222
- OpenAlex
- W2092829811
- Cited by
- 162
- References
- 67
- Citations by year
- 2024: 1 · 2023: 2 · 2022: 4 · 2021: 3 · 2020: 5 · 2019: 6 · 2018: 5 · 2017: 7 · 2016: 6 · 2015: 12 · 2014: 7 · 2013: 9 · 2012: 14
- FWCI
- 7.36
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Neuropsychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Health Sciences › Medicine › Neurology › Neurological disorders and treatments
- Keywords
- Parkinson's disease, depression, prevalence, comorbidities, antidepressants, electroconvulsive therapy, psychotherapy, treatment options
- MeSH terms
- Depression, Humans, Parkinson Disease, Prevalence
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