The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Frontal-subcortical circuits and neuropsychiatric disorders
Abstract
Five parallel anatomic circuits link regions of the frontal cortex to the striatum, globus pallidus/substantia nigra, and thalamus. The circuits originate in the supplementary motor area, frontal eye fields, dorsolateral prefrontal region, lateral orbito-frontal area, and anterior cingulate cortex. Open loop structures that provide input to or receive output from specific circuits share functions, cytoarchitectural features, and phylogenetic histories with the relevant circuits. The circuits mediate motor and oculomotor function as well as executive functions, socially responsive behavior, and motivation. Neuropsychiatric disorders of frontal-subcortical circuits include impaired executive function, disinhibition, and apathy; indicative mood disorders include depression, mania, and lability. Transmitters, modulators, receptor subtypes, and second messengers within the circuits provide a chemoarchitecture that can inform pharmacotherapy.
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Citations
Cites
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Functional architecture of basal ganglia circuits: neural substrates of parallel processing
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Frontal-subcortical circuits and human behavior
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Self-citationNeurotransmitters and neuromodulators in the basal ganglia
Graybiel, A. M. (1990) · Trends in Neurosciences · doi:10.1016/0166-2236(90)90104-i · Cited by 1,576
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Cited by
The emerging field of emotion regulation: an integrative review
Gross, J. J. (1998) · Review of General Psychology · doi:10.1037/1089-2680.2.3.271 · Cited by 9,916
Frontal–subcortical neuronal circuits and clinical neuropsychiatry
Tekin, S., & Cummings, J. L. (2002) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(02)00428-2 · Cited by 1,240
Subcortical ischaemic vascular dementia
Román, G. C., Erkinjuntti, T., Wallin, A., Pantoni, L., & Chui, H. C. (2002) · The Lancet Neurology · doi:10.1016/s1474-4422(02)00190-4 · Cited by 1,067
Functional neuroimaging and the neuroanatomy of obsessive-compulsive disorder
Saxena, S., & Rauch, S. L. (2000) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(05)70181-7 · Cited by 840
Neuroimaging and frontal–subcortical circuitry in obsessive–compulsive disorder
Saxena, S., Brody, A. L., Schwartz, J. M., & Baxter, L. R. (1998) · British Journal of Psychiatry · doi:10.1192/s0007125000297870 · Cited by 831
Metadata
- Venue
- The Journal of Neuropsychiatry and Clinical Neurosciences
- Published
- 1994-11-01
- Volume
- 6
- Issue
- 4
- Pages
- 358-370
- ISSN
- 0895-0172 (ISSN-L)
- 1545-7222
- OpenAlex
- W1548466807
- Cited by
- 725
- References
- 8
- FWCI
- 8.86
- Type
- journal article
- Language
- en
- Open access
- closed
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