Cingulate cortex of the rhesus monkey: I. Cytoarchitecture and thalamic afferents
Abstract
The cytoarchitecture and thalamic afferents of cingulate cortex were evaluated in the rhesus monkey (Macaca mulatta). Area 24 has three divisions of which area 24a is adjacent to the callosal sulcus and has the least laminar differentiation. Area 24b has more clearly defined layers II, III, and Va, and area 24c, which forms the lower bank of the anterior cingulate sulcus, has a particularly dense layer III. Area 23 also has three divisions, each of which has a distinct layer IV. Area 23a is adjacent to the callosal sulcus and has the thinnest layers II-IV, which have the same cell density as layers V and VI. Area 23b has the largest pyramids in layers IIIc and Va, and area 23c, in the depths of the posterior cingulate sulcus, has the broadest external and thinnest internal pyramidal layers. Finally, areas 29 and 30 are located in the posterior depths of the callosal sulcus. Two divisions of area 29 are apparent: one with a granular layer directly adjacent to layer I (area 29a-c) and another with differentiation of layers III and IV (area 29d). Area 30 has a dysgranular layer IV. Injections of the retrograde tracer horseradish peroxidase (HRP) were made into subdivisions of cingulate cortex in the monkey. Area 25 received thalamic input mainly from the midline parataenial (Pt), central densocellular (Cdc), and reuniens nuclei as well as from the dorsal parvicellular division of the mediodorsal nucleus (MDpc). A less dense projection also originated in the intralaminar parafasc…
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Because the amygdala projects to anterior midcingulate cortex, increased anterior midcingulate cortex activity during fear perception may reflect response preparation to salient environmental stimuli.
“The amygdala, which responds to motivationally salient exteroceptive sensory stimuli (see 5.1 The amygdala), projects to this area of aMCC (Vogt & Pandya 1987), so it is possible that increased activity here reflects response preparation to salient stimuli in the environment.”
From The brain basis of emotion: a meta-analytic review (2012) · cites this paper as Vogt & Pandya 1987
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- Authors
- Vogt, B. A., Pandya, D. N., & Rosene, D. L.
- Affiliations
- Boston University (US)
- Venue
- Journal of Comparative Neurology
- Publisher
- Wiley
- Published
- 1987-08-08
- Volume
- 262
- Issue
- 2
- Pages
- 256-270
- ISSN
- 0021-9967 (ISSN-L)
- 1096-9861
- OpenAlex
- W2026360097
- Cited by
- 604
- References
- 1
- Citations by year
- 2026: 6 · 2025: 9 · 2024: 12 · 2023: 10 · 2022: 13 · 2021: 17 · 2020: 10 · 2019: 8 · 2018: 12 · 2017: 15 · 2016: 9 · 2015: 14 · 2014: 12 · 2013: 17 · 2012: 17
- FWCI
- 6.61
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Comparative Neurology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- Centers for Disease Control and Prevention
- National Institute of Neurological Disorders and Stroke (NS16841, NS 19416, NS18745)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- cingulate cortex, rhesus monkeys, cytoarchitecture, thalamic afferents, nucleus reuniens, parafascicular nucleus, mediodorsal nucleus, intralaminar nuclei
- MeSH terms
- Afferent Pathways, Animals, Cerebral Cortex, Gyrus Cinguli, Macaca, Macaca mulatta, Thalamic Nuclei
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