The Association Between Obstructive Sleep Apnea and Carotid Intima–Media Thickness: A Systematic Review and Meta-Analysis
Abstract
Obstructive sleep apnea (OSA) has been suggested as a risk factor for carotid atherosclerosis. The present meta-analysis aimed to evaluate the association between OSA and carotid intima–media thickness (CIMT). Eighteen studies comparing CIMT of patients with OSA versus non-OSA patients were included. Quantitative data synthesis was used to pool weighted standardized difference in means (SMD) of CIMT in a random-effects model. Compared to healthy controls, patients with OSA had a significantly higher CIMT (SMD: 0.881; 95% confidence interval [CI]: 0.647-1.115; P < .001). Due to the great heterogeneity, a subgroup analysis was conducted based on the study design. The pooled SMD of CIMT between patients with OSA and healthy controls were 0.810 (95% CI: 0.676-0.943; P < .001) and 1.008 (95% CI: 0.506-1.510; P < .001) in matched and unmatched group, respectively. Moreover, the correlation of apnea–hypopnea index and CIMT was moderate ( r = .389; 95% CI: 0.315-0.459; P < .001). After adjustment for several major confounders, OSA is an independent risk factor for CIMT. These findings remind clinicians to screen for cardiovascular diseases in patients with OSA.
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Obstructive sleep apnea is an independent risk factor for ASCVD.
“[Statement]Obstructive sleep apnea is an independent risk factor for ASCVD. (Evidence level: E-1b)”
From Japan Atherosclerosis Society (JAS) guidelines for prevention of atherosclerotic cardiovascular diseases 2017 (2018) · cites this paper as [212]
Cites
Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., & Altman, D. G. (2010) · International Journal of Surgery · doi:10.1016/j.ijsu.2010.02.007 · Cited by 12,156 · see citing works
Increased Prevalence of Sleep-Disordered Breathing in Adults
Peppard, P. E., Young, T., Barnet, J. H., Palta, M., Hagen, E. W., & Hla, K. M. (2013) · American Journal of Epidemiology · doi:10.1093/aje/kws342 · Cited by 4,618 · see citing works
Evaluating non-randomised intervention studies
Deeks, J., Dinnes, J., D'Amico, R., Sowden, A., Sakarovitch, C., Song, F., Petticrew, M., & Altman, D. (2003) · Health Technology Assessment · doi:10.3310/hta7270 · Cited by 2,907 · see citing works
Sympathetic neural mechanisms in obstructive sleep apnea.
Somers, V. K., Dyken, M. E., Clary, M. P., & Abboud, F. M. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118235 · Cited by 2,527 · see citing works
Dyugovskaya, L., Lavie, P., & Lavie, L. (2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.165.7.2104126 · Cited by 742 · see citing works
Crouse, J. R., Raichlen, J. S., Riley, W. A., Evans, G. W., Palmer, M. K., O’Leary, D. H., Grobbee, D. E., Bots, M. L., & for the METEOR Study Group (2007) · JAMA · doi:10.1001/jama.297.12.1344 · Cited by 708 · see citing works
The new AASM criteria for scoring hypopneas: impact on the apnea hypopnea index
Ruehland, W. R., Rochford, P. D., O’Donoghue, F. J., Pierce, R. J., Singh, P., & Thornton, A. T. (2009) · SLEEP · doi:10.1093/sleep/32.2.150 · Cited by 696 · see citing works
Early Signs of Atherosclerosis in Obstructive Sleep Apnea
Drager, L. F., Bortolotto, L. A., Lorenzi, M. C., Figueiredo, A. C., Krieger, E. M., & Lorenzi‐Filho, G. (2005) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200503-340oc · Cited by 596 · see citing works
ARBITER: Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol
Taylor, A. J., Kent, S. M., Flaherty, P. J., Coyle, L. C., Markwood, T. T., & Vernalis, M. (2002) · Circulation · doi:10.1161/01.cir.0000034508.55617.65 · Cited by 558 · see citing works
Drager, L. F., Bortolotto, L. A., Figueiredo, A. C., Krieger, E. M., & Lorenzi‐Filho, G. (2007) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200703-500oc · Cited by 558 · see citing works
Oxidative stress and endothelial dysfunction in hypertension
Schulz, E., Gori, T., & Münzel, T. F. (2011) · Hypertension Research · doi:10.1038/hr.2011.39 · Cited by 503 · see citing works
Increased Carotid Intima-Media Thickness and Serum Inflammatory Markers in Obstructive Sleep Apnea
Minoguchi, K., Yokoe, T., 田崎, 俊., Minoguchi, H., Tanaka, A., Oda, N., Okada, S., Ohta, S., Naito, H., & Adachi, M. (2005) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200412-1652oc · Cited by 421 · see citing works
Evidence for Lipid Peroxidation in Obstructive Sleep Apnea
Lavie, L., Vishnevsky, A., & Lavie, P. (2004) · SLEEP · doi:10.1093/sleep/27.1.123 · Cited by 385 · see citing works
Wang, X., Ouyang, Y., Wang, Z., Zhao, G., Liu, L., & Bi, Y. (2013) · International Journal of Cardiology · doi:10.1016/j.ijcard.2013.08.088 · Cited by 324 · see citing works
Invited Review: Physiological and pathophysiological responses to intermittent hypoxia
Neubauer, J. A. (2001) · Journal of Applied Physiology · doi:10.1152/jappl.2001.90.4.1593 · Cited by 302 · see citing works
Larkin, E. K., Rosen, C. L., Kirchner, H. L., Storfer-Isser, A., Emancipator, J. L., Johnson, N. L., Zambito, A. M. V., Tracy, R. P., Jenny, N. S., & Redline, S. (2005) · Circulation · doi:10.1161/01.cir.0000161819.76138.5e · Cited by 246 · see citing works
The Severity of Oxygen Desaturation Is Predictive of Carotid Wall Thickening and Plaque Occurrence
Baguet, J.-P., Hammer, L., Leívy, P., Pierre, H., Launois, S. H., Mallion, J.-M., & Pépin, J. (2005) · CHEST Journal · doi:10.1378/chest.128.5.3407 · Cited by 227 · see citing works
Chronic intermittent hypoxia activates nuclear factor-κB in cardiovascular tissues in vivo
Greenberg, H. E., Ye, X., Wilson, D., Htoo, A. K., Hendersen, T., & Liu, S. F. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.03.015 · Cited by 225 · see citing works
HDL dysfunction in obstructive sleep apnea
Tan, K. C. B., Chow, W.-S., Lam, J., LAM, B. K., Wong, W.-K., Tam, S., & Ip, M. (2005) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2005.04.024 · Cited by 200 · see citing works
Obstructive sleep apnea and dyslipidemia: evidence and underlying mechanism
Adedayo, A. M., Olafiranye, O., Smith, D., Hill, A., Zizi, F., Brown, C., & Jean-Louis, G. (2014) · Sleep and Breathing · doi:10.1007/s11325-012-0760-9 · Cited by 182 · see citing works
Drager, L. F., Bortolotto, L. A., Krieger, E. M., & Lorenzi‐Filho, G. (2008) · Hypertension · doi:10.1161/hypertensionaha.108.119420 · Cited by 164 · see citing works
Savransky, V., Jun, J. C., Li, J., Nanayakkara, A., Bevans‐Fonti, S., Moser, A. B., Steele, K., Schweitzer, M., Patil, S. P., Bhanot, S., et al. (2008) · Circulation Research · doi:10.1161/circresaha.108.178533 · Cited by 153 · see citing works
Potential underdiagnosis of obstructive sleep apnoea in the cardiology outpatient setting
Costa, L. E., Uchôa, C. H. G., Harmon, R. R., Bortolotto, L. A., Lorenzi‐Filho, G., & Drager, L. F. (2015) · Heart · doi:10.1136/heartjnl-2014-307276 · Cited by 133 · see citing works
Rosvall, M., Persson, M., Östling, G., Nilsson, P. M., Melander, O., Hedblad, B., & Engström, G. (2015) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2015.01.030 · Cited by 131 · see citing works
Ciccone, M. M., Scicchitano, P., Zito, A., Cortese, F., Boninfante, B., Falcone, V. A., Quaranta, V. N., Ventura, V. A., Zucano, A., Serio, F. D., et al. (2014) · Molecules · doi:10.3390/molecules19021651 · Cited by 109 · see citing works
Nena, E., Παπάνας, Ν., Steiropoulos, P., Zikidou, P., Zarogoulidis, P., Pita, E., Constantinidis, T. C., Maltezos, E. S., Mikhailidis, D. P., & Bouros, D. E. (2011) · Platelets · doi:10.3109/09537104.2011.632031 · Cited by 102 · see citing works
Obstructive sleep apnea, cardiovascular disease, and inflammation—is NF-κB the key?
Williams, A. L., & Scharf, S. M. (2007) · Sleep And Breathing · doi:10.1007/s11325-007-0106-1 · Cited by 101 · see citing works
Yun, C., Jung, K., Chu, K., Kim, S., Ji, K., Park, H.-K., Kim, H., Lee, S., Lee, S.-K., & Roh, J. (2010) · Journal of Clinical Neurology · doi:10.3988/jcn.2010.6.2.89 · Cited by 101 · see citing works
Serum Amyloid A in Obstructive Sleep Apnea
Svatikova, A., Wolk, R. A., Shamsuzzaman, A., Kára, T., Olson, E. J., & Somers, V. K. (2003) · Circulation · doi:10.1161/01.cir.0000089091.09527.b8 · Cited by 98 · see citing works
Mean platelet volume is increased in patients with severe obstructive sleep apnea
Varol, E., Öztürk, Ö., Gonca, T., Has, M., Özaydın, M., Erdoğan, D., & Akkaya, A. (2010) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.3109/00365513.2010.520733 · Cited by 91 · see citing works
Snoring-related energy transmission to the carotid artery in rabbits
Amatoury, J., Howitt, L., Wheatley, J. R., Avolio, A. P., & Amis, T. C. (2006) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01439.2005 · Cited by 84 · see citing works
Low Impact of Traditional Risk Factors on Carotid Intima-Media Thickness
Santos, I. S., Alencar, A. P., Rundek, T., Goulart, A. C., Barreto, S. M., Pereira, A. C., Benseñor, I. M., & Lotufo, P. A. (2015) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.115.305765 · Cited by 77 · see citing works
Tanriverdi, H. I., Evrengül, H., Kara, C. O., Kuru, Ö., Tanrıverdi, S., Özkurt, S., Kaftan, A., & Kılıç, M. (2006) · Respiration · doi:10.1159/000093531 · Cited by 72 · see citing works
Kabłak-Ziembicka, A., Przewłocki, T., Sokołowski, A., Tracz, W., & Podolec, P. S. (2010) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2010.10.017 · Cited by 69 · see citing works
Vascular Impairment in Alzheimer's Disease: The Role of Obstructive Sleep Apnea
Buratti, L., Viticchi, G., Falsetti, L., Cagnetti, C., Luzzi, S., Bartolini, M., Provinciali, L., & Silvestrini, M. (2013) · Journal of Alzheimer s Disease · doi:10.3233/jad-131046 · Cited by 65 · see citing works
Nagai, K., Shibata, S., Akishita, M., Sudoh, N., Obara, T., Toba, K., & Kozaki, K. (2013) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2013.09.028 · Cited by 63 · see citing works
nsalo, M. P. I., Rantala, A. O., Kauma, H., Lilja, M., Reunanen, A., Savolainen, M. J., Kes�niemi, A., & Suramo, I. (1996) · Journal of Hypertension · doi:10.1097/00004872-199612000-00008 · Cited by 55 · see citing works
Hui, D. S. C., Shang, Q., Ko, F. W. S., Ng, S. S., Szeto, C., Ngai, J. C. L., Tung, A., To, K., Chan, T., & Yu, C. (2012) · Respiratory Research · doi:10.1186/1465-9921-13-22 · Cited by 52 · see citing works
Neural and humoral mechanisms mediating cardiovascular responses to obstructive sleep apnea
Phillips, B. G., & Somers, V. K. (2000) · Respiration Physiology · doi:10.1016/s0034-5687(99)00113-9 · Cited by 52 · see citing works
Patients with Obstructive Sleep Apnea Display Increased Carotid Intima Media: A Meta-Analysis
Nadeem, R. N., Harvey, M., Singh, M., Khan, A. A., Albustani, M., Baessler, A. M., Madbouly, E. M., Hassan, S., Khan, M., & Navid, N. (2013) · International Journal of Vascular Medicine · doi:10.1155/2013/839582 · Cited by 46 · see citing works
Sleep apnoea inducing hypoxemia is associated with early signs of carotid atherosclerosis in males
Szabóová, E., Tomori, Z., Donič, V., Petrovičová, J., & Szabó, P. G. (2006) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2006.05.004 · Cited by 38 · see citing works
Joyeux‐Faure, M., Tamisier, R., Baguet, J.-P., Dias-Domingos, S., Perrig, S. H., Lefthériotis, G., Janssens, J.-P., Trzépizur, W., Launois, S. H., Stanke‐Labesque, F., et al. (2014) · Mediators of Inflammation · doi:10.1155/2014/423120 · Cited by 34 · see citing works
Aşker, S., Aşker, M., Yeltekin, A. Ç., Aslan, M., & Demir, H. (2014) · Sleep And Breathing · doi:10.1007/s11325-014-1045-2 · Cited by 33 · see citing works
Salepçi, B. M., Fidan, A., Ketenci, S. C., Parmaksız, E. T., Cömert, S. Ş., Kıral, N., Aktürk, Ü. A., Caglayan, B. N., & Salepci, E. (2014) · Sleep And Breathing · doi:10.1007/s11325-014-1002-0 · Cited by 33 · see citing works
Guvener, N. D., Tütüncü, N. B., Oto, A., & Erbas, T. A. (2000) · Endocrine Journal · doi:10.1507/endocrj.47.525 · Cited by 29 · see citing works
Is excessive daytime sleepiness a predictor of carotid atherosclerosis in sleep apnea?
Saletu, M., Sauter, C., Lalouschek, W., Saletu, B., Kapfhammer, G., Benesch, T., & Zeitlhofer, J. (2007) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2007.01.016 · Cited by 29 · see citing works
Ikeda, K., Takahashi, T., Yamada, H., Matsui, K., Sawada, T., Nakamura, T., Matsubara, H., & (for the PEACE Investigators) (2012) · European Journal of Preventive Cardiology · doi:10.1177/2047487312451539 · Cited by 28 · see citing works
Prejbisz, A., Florczak, E., Pręgowska−Chwała, B., Klisiewicz, A., Kuśmierczyk‐Droszcz, B., Zieliński, T., Makowiecka‐Cieśla, M., Kołodziejczyk‐Kruk, S., Śliwiński, P., & Januszewicz, A. (2014) · Hypertension Research · doi:10.1038/hr.2014.43 · Cited by 27 · see citing works
Sayhan, H. (2014) · Medical Science Monitor · doi:10.12659/msm.891001 · Cited by 26 · see citing works
Lee, S., Cho, G., Kim, H., Yoon, Y. E., Lee, S., Kim, H., Kim, Y.-J., & Sohn, D. (2014) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2014.06.026 · Cited by 20 · see citing works
Akyüz, A., Oran, M., Alpsoy, Ş., Mutlu, L. C., Akkoyun, D. Ç., Güzel, S., & Alp, R. (2013) · Angiology · doi:10.1177/0003319713497421 · Cited by 19 · see citing works
Tan, T., Liou, C., Friedman, M., Lin, H., Chang, H., & Lin, M. (2012) · The Neurologist · doi:10.1097/nrl.0b013e3182675344 · Cited by 17 · see citing works
Kaul, S., Alladi, S., Kandadai, R. M., Bandaru, S. V. C. S., Boddu, D. B., Anjanikumar, D., & Umamashesh, M. (2015) · Annals of Indian Academy of Neurology · doi:10.4103/0972-2327.165481 · Cited by 16 · see citing works
Steiropoulos, P., Bogiatzi, C., Archontogeorgis, K., Nena, E., Xanthoudaki, M., Boglou, P., Tzouvelekis, A., Papanas, N., Tsivgoulis, G. K., & Bouros, D. (2013) · The Open Cardiovascular Medicine Journal · doi:10.2174/1874192401307010061 · Cited by 10 · see citing works
Akdağ, S., Akyol, A., Çakmak, H. A., Günbatar, H., Aşker, M., Babat, N., Tosu, A. R., Yaman, M., & Gümrükçüoğlu, H. A. (2015) · Korean Circulation Journal · doi:10.4070/kcj.2015.45.6.500 · Cited by 8 · see citing works
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Sorted by citations
Kinoshita, M., Yokote, K., Arai, H., Iida, M., Ishigaki, Y., Ishibashi, S., Umemoto, S., Egusa, G., Ohmura, H., Okamura, T., et al. (2018) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.gl2017 · Cited by 813 · see citing works
Salman, L. A., Shulman, R., & Cohen, J. B. (2020) · Current Cardiology Reports · doi:10.1007/s11886-020-1257-y · Cited by 330 · see citing works
Zhang, X., Wang, S., Xu, H., Yi, H., Guan, J., & Yin, S. (2021) · European Respiratory Review · doi:10.1183/16000617.0220-2020 · Cited by 82 · see citing works
Sleep disorders, nocturnal blood pressure, and cardiovascular risk: A translational perspective
Silvani, A. (2019) · Autonomic Neuroscience · doi:10.1016/j.autneu.2019.02.006 · Cited by 68 · see citing works
Li, L., Yang, Y., Zhang, H., Du, Y., Jiao, X., Yu, H., Wang, Y., Lv, Q., Li, F., Sun, Q., et al. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.723922 · Cited by 51 · see citing works
Self-citationHarki, O., Boëté, Q., Pépin, J., Arnaud, C., Belaïdi, E., Faury, G., Khouri, C., & Briançon‐Marjollet, A. (2021) · European Respiratory Journal · doi:10.1183/13993003.00866-2021 · Cited by 51 · see citing works
PAI-1: A Major Player in the Vascular Dysfunction in Obstructive Sleep Apnea?
Badran, M., & Gozal, D. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23105516 · Cited by 36 · see citing works
Souza, S. P., Santos, R. B., Santos, I. S., Parise, B. K., Giatti, S., Aielo, A. N., da Cunha, L. F., Silva, W. A., Bortolotto, L. A., Lorenzi‐Filho, G., et al. (2021) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.120.315644 · Cited by 32 · see citing works
Relationship of obstructive sleep apnoea severity and subclinical systemic atherosclerosis
Kim, S., Lee, K. Y., Kim, N. H., Abbott, R. D., Kim, C., Lee, S. K., Kim, S. H., & Shin, C. (2019) · European Respiratory Journal · doi:10.1183/13993003.00959-2019 · Cited by 29 · see citing works
Chen, L., Lin, L., Lin, X., Ou, Y., Wu, Z., Ye, Y.-M., Xu, Q.-Z., Huang, Y., & Cai, Z. (2017) · PLoS ONE · doi:10.1371/journal.pone.0184293 · Cited by 28 · see citing works
Targeting subclinical organ damage in obstructive sleep apnea: a narrative review
Cuspidi, C., Tadic, M. V., Gherbesi, E., Sala, C., & Grassi, G. M. (2020) · Journal of Human Hypertension · doi:10.1038/s41371-020-00397-0 · Cited by 29 · see citing works
Adeva‐Andany, M. M., Domínguez-Montero, A., Castro-Quintela, E., Funcasta-Calderón, R., & Fernández‐Fernández, C. (2024) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm2506231 · Cited by 24 · see citing works
Lisan, Q., van Sloten, T. T., Boutouyrie, P., Laurent, S., Danchin, N., Thomas, F., Guibout, C., Perier, M., Dagnelie, P. C., Henry, R. M. A., et al. (2021) · Journal of the American Heart Association · doi:10.1161/jaha.120.021318 · Cited by 23 · see citing works
Ragia, G., Archontogeorgis, K., Simmaco, M., Gentile, G., Borro, M., Zissimopoulos, A., Froudarakis, Μ. E., Manolopoulos, V. G., & Steiropoulos, P. (2018) · OMICS A Journal of Integrative Biology · doi:10.1089/omi.2018.0184 · Cited by 22 · see citing works
Chen, W., Li, Y., Guo, L., Zhang, C., & Tang, S. (2021) · Sleep And Breathing · doi:10.1007/s11325-021-02384-2 · Cited by 19 · see citing works
Early Atherosclerotic Inflammatory Pathways in Children with Obstructive Sleep Apnea
Smith, D. F., Schuler, C. L., Hossain, M. M., Huang, G., McConnell, K. B., Urbina, E. M., & Amin, R. S. (2021) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2021.08.031 · Cited by 18 · see citing works
Obstructive sleep apnoea and cardiovascular disease: a literature review
Assallum, H., Song, T.-Y., Aronow, W. S., & Chandy, D. (2019) · Archives of Medical Science · doi:10.5114/aoms.2019.88558 · Cited by 15 · see citing works
Burns, D., Chan, V. W. S., Trivedi, A., Englesakis, M. F., Munshey, F., & Singh, M. (2022) · Journal of Clinical Anesthesia · doi:10.1016/j.jclinane.2022.110973 · Cited by 15 · see citing works
Hao, W., Wang, X., Fan, J., Zeng, Y., Ai, H., Nie, S., & Wei, Y. (2021) · Annals of Medicine · doi:10.1080/07853890.2021.1875137 · Cited by 15 · see citing works
Apnea obstructiva del sueño y riesgo cardiovascular
Torres, G., Sánchez‐de‐la‐Torre, M., Pinilla, L., & Barbé, F. (2024) · Clínica e Investigación en Arteriosclerosis · doi:10.1016/j.arteri.2024.01.004 · Cited by 13 · see citing works
Sleep apnoea and the neurologist
Cheng, S., Stark, C., & Stark, R. J. (2016) · Practical Neurology · doi:10.1136/practneurol-2016-001524 · Cited by 11 · see citing works
Saba, L., Maindarkar, M. A., Khanna, N. N., Puvvula, A., Faa, G., Isenović, E. R., Johri, A. M., Fouda, M. M., Tiwari, E., Kalra, M. K., et al. (2024) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm2512463 · Cited by 9 · see citing works
Obstructive sleep apnea and cardiovascular risk
Torres, G., Sánchez‐de‐la‐Torre, M., Pinilla, L., & Barbé, F. (2024) · Clínica e Investigación en Arteriosclerosis (English Edition) · doi:10.1016/j.artere.2024.07.003 · Cited by 10 · see citing works
Chuang, H., Liu, C., Wang, C.-Y., Lo, Y.-L., Lee, G., Chao, Y., Li, H., Kuo, T. B. J., Yang, C. C. H., Shyu, L.-Y., et al. (2021) · Nature and Science of Sleep · doi:10.2147/nss.s311125 · Cited by 9 · see citing works
Quantitative analysis of carotid arterial calcification using airway CT in obstructive sleep apnea
Koh, T. K., Kang, E., Bae, W. Y., Kim, S. W., Kim, C. H., Koo, S. K., Kim, S. J., Kim, M. S., & Lee, J. H. (2018) · Auris Nasus Larynx · doi:10.1016/j.anl.2018.11.015 · Cited by 5 · see citing works
Hao, Z., Qin, L., Tong, J., Li, N., Zhai, Y., & Zhao, Y. X. (2020) · Sleep And Breathing · doi:10.1007/s11325-020-02145-7 · Cited by 3 · see citing works
Nithitsutthibuta, K., Sonsuwan, N., Uthaikhup, S., Kiatwattanacharoen, S., Kunritt, J., & Pratanaphon, S. (2025) · Cardiovascular Endocrinology & Metabolism · doi:10.1097/xce.0000000000000342 · Cited by 2 · see citing works
What is important for an internist to know about sleep?
Brodovskaya, T. O., Грищенко, О. О., Bazhenova, O. V., & Grishina, I. F. (2023) · Ural Medical Journal · doi:10.52420/2071-5943-2023-22-1-120-126 · Cited by 1 · see citing works
Sulina, D., Puskás, S., Magyar, M. T., Oláh, L., & Kozák, N. (2025) · Sleep And Breathing · doi:10.1007/s11325-024-03189-9 · Cited by 1 · see citing works
Increased Carotid Intima–Media Thickness in Obstructive Sleep Apnea: An Additional Issue to Consider
Steiropoulos, P., & Παπάνας, Ν. (2017) · Angiology · doi:10.1177/0003319717705270 · Cited by 1 · see citing works
Lambeth, C., Perri, R. A., Lee, S. C. L., Verma, M., Campbell‐Rogers, N., Larcos, G., Byth, K., Kairaitis, K., Amis, T. C., & Wheatley, J. R. (2021) · PLoS ONE · doi:10.1371/journal.pone.0252569 · Cited by 1 · see citing works
Obstructive Sleep Apnea Syndrome Causes Vascular Dysfunction, Similarly with Diabetes Mellitus
Magda, L.-S. (2019) · Journal of Cardiology & Cardiovascular Therapy · doi:10.19080/jocct.2019.13.555862
Jokkel, Z., Szily, M., Piroska, M., Szabó, H., Hernyes, A., Szabó, G., Kalina, I., Maurovich‐Horvat, P., Tárnoki, D. L., & Tárnoki, Á. D. (2023) · Applied Sciences · doi:10.3390/app13179953
Iron Metabolism Dysregulation and Atherosclerotic Changes in Obstructive Sleep Apnoea
Manolov, V., Georgiev, O. B., Vasilev, V., Emilova, R., Petrova, I., Hadjidekova, S. P., Angov, G., Kunchev, T., Tzatchev, K., Traykov, L. D., et al. (2023) · Proceedings of the Bulgarian Academy of Sciences · doi:10.7546/crabs.2023.10.17
Mosiewicz, J., Brożyna-Tkaczyk, K., Reichert, E., Myśliński, W., Panasiuk, L., Jaroszyński, A., & Mosiewicz-Madejska, B. (2023) · Annals of Agricultural and Environmental Medicine · doi:10.26444/aaem/177205 · Cited by 1 · see citing works
Mondal, R. K., Takashima, N., Torii, S., Harada, A., Azahar, N., Moniruzzaman, M., Kondo, K., Kadowaki, S., Kadota, A., Yano, Y., et al. (2025) · BMJ Open · doi:10.1136/bmjopen-2023-082584
The Effect of CPAP Treatment on Carotid Intima-Media Thickness in Patients with OSA: A Meta-Analysis
李, 翔. (2025) · Advances in Clinical Medicine · doi:10.12677/acm.2025.1561694
Han, Y., Fu, L., Jia, X., Wang, Y., Li, Y., & Zou, J. (2025) · SSRN Electronic Journal · doi:10.2139/ssrn.5325457
Self-citationMalinsky, R. R., Jacobowitz, O., & Ibrahim, B. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-12563-8.00017-3
- Authors
- Zhou, M., Guo, B., Wang, Y., Yan, D., Lin, C., & Shi, Z.
- Affiliations
- Fudan University (CN)
- Corresponding author
- Shi, Zhenyu
- ORCID
- Venue
- Angiology
- Publisher
- SAGE Publications
- Published
- 2016-08-31
- Volume
- 68
- Issue
- 7
- Pages
- 575-583
- ISSN
- 0003-3197 (ISSN-L)
- 1940-1574
- OpenAlex
- W2512648874
- Cited by
- 39
- References
- 55
- Citations by year
- 2025: 5 · 2024: 4 · 2023: 5 · 2022: 2 · 2021: 10 · 2020: 3 · 2019: 4 · 2018: 3 · 2017: 2 · 2016: 1
- FWCI
- 0.39
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Angiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Health Sciences › Medicine › Pharmacology › Apelin-related biomedical research
- Keywords
- obstructive sleep apnea, carotid intima-media thickness, carotid atherosclerosis, apnea-hypopnea index, cardiovascular risk factors, cardiovascular screening
- MeSH terms
- Cardiovascular Diseases, Carotid Artery Diseases, Humans, Risk Factors, Polysomnography, Sleep Apnea, Obstructive, Carotid Intima-Media Thickness
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