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Cited by 284

The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.

In vitro Studies on the Effects of Fluoride on De- and Remineralization

Cate, J.M. Ten·1990·Journal of Dental Research

Abstract

The recent literature extensively describes the role of ambient fluoride in the de- and remineralization of dental enamel. Fluoride in sub-ppm concentrations is effective in promoting mineral deposition and inhibiting mineral dissolution. The latter phenomenon is most likely attributable to the concomitant precipitation of a fluoride-rich mineral phase which inhibits further dissolution. These fundamental processes result in an inhibition of enamel demineralization and an enhancement of enamel lesion remineralization. Alternatively, fluoride may also induce the ‘arrestment’ of enamel lesions. For the in vivo patterns and the effects of caries-preventive substances to be studied, de- and remineralization can best be examined with a pH-cycling system in which the pH depressions occurring in the oral environment are mimicked in a laboratory model. Such an approach has proved useful in developing optimal fluoride schemes which can be tested in animal, intraoral, and clinical studies.

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Metadata

Authors
Cate, J. M. T.
Venue
Journal of Dental Research
Published
1990-02
Volume
69
Issue
2_suppl
Pages
614-619
ISSN
  • 0022-0345 (ISSN-L)
  • 1544-0591
OpenAlex
W2170751933
Cited by
284
References
25
FWCI
6.09
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: In vitro Studies on the Effects of Fluoride on De- and Remineralization. https://app.cochat.ai/papers/10.1177/00220345900690s120
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Cate, J. M. T. (1990). In vitro Studies on the Effects of Fluoride on De- and Remineralization. Journal of Dental Research. https://doi.org/10.1177/00220345900690s120

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.