The Obesity‐Survival Paradox in Hemodialysis Patients: Why Do Overweight Hemodialysis Patients Live Longer?
Abstract
Obesity is increasingly common in the United States, and it frequently coexists with diabetes and hypertension. Given that diabetes and hypertension are the 2 most common causes of end‐stage renal disease, it is not surprising that obesity is also highly prevalent in the US hemodialysis population. However, unlike in the general population, obesity is associated with improved survival in hemodialysis patients. This phenomenon, the obesity‐survival paradox, is neither universally accepted nor completely understood. In this article, we review the available data and provide potential reasons for the obesity‐survival paradox in the dialysis population.
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A protective effect of obesity has been seen in hemodialysis patients, evidenced by improved survival in those with higher BMIs.
“Lastly, a protective effect of obesity has been seen in hemodialysis patients evidenced by improved survival in those with higher BMIs (164, 307, 311).”
From Cardiac remodeling in obesity (2008) · cites this paper as [311]
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- Authors
- Schmidt, D., & Salahudeen, A.
- Affiliations
- University of Mississippi Medical Center (US)
- The University of Texas MD Anderson Cancer Center (US)
- Corresponding author
- Schmidt, Darren
- Venue
- Nutrition in Clinical Practice
- Publisher
- Wiley
- Published
- 2007-02
- Volume
- 22
- Issue
- 1
- Pages
- 11-15
- ISSN
- 0884-5336 (ISSN-L)
- 1941-2452
- OpenAlex
- W2135951576
- Cited by
- 62
- References
- 42
- Citations by year
- 2024: 1 · 2023: 4 · 2022: 3 · 2021: 6 · 2020: 3 · 2019: 2 · 2018: 3 · 2017: 5 · 2016: 3 · 2015: 4 · 2014: 5 · 2013: 1 · 2012: 7
- FWCI
- 0.70
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Nutrition in Clinical Practice (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Nephrology › Dialysis and Renal Disease Management
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Health Sciences › Medicine › Nephrology › Chronic Kidney Disease and Diabetes
- Keywords
- obesity, hemodialysis, survival, end-stage renal disease, overweight, diabetes mellitus, hypertension, dialysis patients
- MeSH terms
- Renal Dialysis, Humans, Kidney Failure, Chronic, Obesity, Survival Rate
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