The DOI matches its Crossref record; 43 of the 51 references it cites were found in a registry or an index.
Depression in Patients with Tinnitus: A Systematic Review
Open accessAbstract
Objective: Tinnitus is a condition that causes distress and impairment across cognitive, functional, and psychiatric spectra. In the psychiatric realm, tinnitus has long been associated with depression. To better characterize the co‐occurrence of depression and tinnitus, we performed a systematic review of the prevalence of depression among patients with tinnitus. Data Sources: We comprehensively examined original studies reporting the prevalence of depression in adult populations with tinnitus, as indexed in the PubMed and Web of Science databases and published from January 2006 to August 2016. Review Methods: All identified articles were reviewed independently by 2 researchers, with a third reviewer for adjudication. Included studies were evaluated for threats to validity across 3 domains—representativeness, response rate, and ascertainment of outcome—on a 4‐point modified Newcastle‐Ottawa Quality Assessment Scale. Results: Twenty‐eight studies were included, representing 15 countries and 9979 patients with tinnitus. Among the included studies, the median prevalence of depression was 33%, with an interquartile range of 19% to 49% and an overall range of 6% to 84%. Studies were high quality overall, with a mean score of 3.3 (SD = 0.76), and 89% utilized a validated tool to ascertain depression. Conclusions: We conducted one of the largest contemporary comprehensive reviews, which suggests a 33% prevalence of depression among patients with tinnitus. Our review reaffirms that a substantial proportion of patients with tinnitus have depression, and we recommend that all who treat tinnitus should screen and treat their patients for depression, if present.
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Cites
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Beukes, E. W., Baguley, D., Jacquemin, L., Lourenco, M. P. C. G., Allen, P. M., Onozuka, J., Stockdale, D., Kaldo, V., Andersson, G., & Manchaiah, V. K. C. (2020) · Frontiers in Public Health · doi:10.3389/fpubh.2020.592878 · Cited by 101
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“It is also associated with an increased risk of psychological difficulties, such as anxiety, depression, and reduced quality of life [4,5].”
Background
Metadata
- Authors
- Salazar, J. W., Meisel, K., Smith, E. R., Quiggle, A., McCoy, D. B., & Amans, M. R.
- Affiliations
- University of California, San Francisco (US)
- Medical College of Wisconsin (US)
- Corresponding author
- Amans, Matthew R.
- Venue
- Otolaryngology–Head and Neck Surgery
- Publisher
- Wiley
- Published
- 2019-03-26
- Volume
- 161
- Issue
- 1
- Pages
- 28-35
- ISSN
- 0161-6439 (ISSN-L)
- 0194-5998
- 1097-6817
- PMC
- PMC7721477
- OpenAlex
- W2924425350
- Cited by
- 167
- References
- 51
- Citations by year
- 2026: 18 · 2025: 40 · 2024: 33 · 2023: 14 · 2022: 24 · 2021: 24 · 2020: 10 · 2019: 3
- FWCI
- 2.64
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Otolaryngology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- National Institute on Deafness and Other Communication Disorders (R21DC016087)
- Topics
- Life Sciences › Neuroscience › Sensory Systems › Hearing, Cochlea, Tinnitus, Genetics
- Health Sciences › Health Professions › Speech and Hearing › Hearing Loss and Rehabilitation
- Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
- Keywords
- tinnitus, depression, depression prevalence, comorbidities, psychiatric comorbidity, depression screening, depression treatment
- MeSH terms
- Depression, Humans, Tinnitus, Prevalence
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