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Prevalence of depression in survivors of acute myocardial infarction: Review of the evidence

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Thombs, Brett D., Bass, Eric B., Ford, Daniel E., Stewart, Kerry J., Tsilidis, Konstantinos K., Patel, Udita, Fauerbach, James A., Bush, David E. +1 more·2006·Journal of General Internal Medicine
DOI 10.1111/j.1525-1497.2005.00269.xPMC PMC1484630
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Abstract

Objectives To assess the prevalence and persistence of depression in patients with acute myocardial infarction (AMI) and the relationship between assessment modality and prevalence.Data sources MEDLINE, Cochrane, CINAHL, PsycINFO, and EMBASE.Review methods A comprehensive search was conducted in March 2004 to identify original research studies published since 1980 that used a standardized interview or validated questionnaire to assess depression. The search was augmented by hand searching of selected journals from October 2003 through April 2004 and references of identified articles and reviews. Studies were excluded if only an abstract was provided, if not in English, or if depression was not measured by a validated method.Results Major depression was identified in 19.8% (95% confidence interval [CI] 19.1% to 20.6%) of patients using structured interviews (N=10,785, 8 studies). The prevalence of significant depressive symptoms based on a Beck Depression Inventory score > or =10 was 31.1% (CI 29.2% to 33.0%; N=2,273, 6 studies), using a Hospital Anxiety and Depression Scale (HADS) score > or =8%, 15.5% (CI 13.2% to 18.0%; N=863, 4 studies), and with a HADS score > or =11%, 7.3% (CI 5.5% to 9.3%; N=830, 4 studies). Although a significant proportion of patients continued to be depressed in the year after discharge, the limited number of studies and variable follow-up times precluded specification of prevalence rates at given time points.Conclusions Depression is common and persistent in AMI survivors. Prevalence varies depending on assessment method, likely reflecting treatment of somatic symptoms.

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  • Mental disorders are common among patients with severe cardiovascular diseases (CVD).

    “Mental disorders are common among patients with severe cardiovascular diseases (CVD).”

    From Metacognitive Short-Term Intervention in Patients With Mental Disorders Following Cardiovascular Events (2022) · cites this paper as [1]

    The Discussion (page unavailable) reports that major depression was present in approximately one in five patients hospitalized for acute myocardial infarction. This supports the claim for depression in that patient group, but the paper does not establish that mental disorders generally are common across severe cardiovascular diseases. (LLM, conf=0.85)

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  • Symptoms of depression and anxiety are common after an acute myocardial infarction (MI).

    “Symptoms of depression and anxiety are common after a myocardial infarction (MI).”

    From Internet-based cognitive behavioral therapy for symptoms of depression and anxiety among patients with a recent myocardial infarction: The u-care heart randomized Controlled trial (2018) · cites this paper as [1]

    The Discussion (page not specified) reports that about one in three patients hospitalized for acute MI had at least mild-to-moderate depressive symptoms, supporting the depression part of the claim. The paper cites studies involving anxiety but does not report that anxiety symptoms are common after MI. (LLM, conf=0.88)

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1 of the 81 references couldn’t be matched to a known paper.

Research works printed but not linked: 4

  1. Frasure-Smith N, Lesperance F, Talajic M. Depression following myo- cardial infarction. Impact on 6-month survival. JAMA. 1993;270:1819- 25.
  2. First MB, Spitzer RL, Gibbon M, Williams J. Structured Clinical In- terview for DSM-IV Axis I Disorders-Patient Edition (SCID-I/P, Version 2.0). New York: Biometrics Research Department, New York State Psy- chiatric Institute; 1996.
  3. Platt RW, Hanley JA, Yang H. Bootstrap confidence intervals for the sensitivity of a quantitative diagnostic test. Stat Med. 2000;19:313-22.
  4. Steeds RP, Bickerton D, Smith MJ, Muthusamy R. Assessment of de- pression following acute myocardial infarction using the Beck Depres- sion Inventory. Heart. 2004;90:217-8.

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Authors
Thombs, B. D., Bass, E. B., Ford, D. E., Stewart, K. J., Tsilidis, K. K., Patel, U., Fauerbach, J. A., Bush, D. E., & Ziegelstein, R. C.
Affiliations
Johns Hopkins University (US)
Corresponding author
Ziegelstein, Roy C.
ORCID
Venue
Journal of General Internal Medicine
Publisher
Springer Science and Business Media LLC
Published
2006-01
Volume
21
Issue
1
Pages
30-38
ISSN
  • 0884-8734 (ISSN-L)
  • 1525-1497
DOI
10.1111/j.1525-1497.2005.00269.x
PMC
PMC1484630
OpenAlex
W1481220499
Cited by
841
References
81
Citations by year
2026: 22 · 2025: 28 · 2024: 26 · 2023: 53 · 2022: 47 · 2021: 45 · 2020: 49 · 2019: 50 · 2018: 62 · 2017: 55 · 2016: 64 · 2015: 55 · 2014: 46 · 2013: 47 · 2012: 47
FWCI
2.23
Type
journal article
Language
en
Open access
Locations
  • Journal of General Internal Medicine (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • eScholarship@McGill (McGill) (submittedVersion)
Funders
U.S. Public Health Service (290-02-0018)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
  • Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
Keywords
depression, acute myocardial infarction, depression prevalence, depression persistence, depressive symptoms, Beck Depression Inventory, Hospital Anxiety and Depression Scale, somatic symptoms
MeSH terms
Depressive Disorder, Hospitalization, Humans, Myocardial Infarction, Prevalence

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