Early Clinical Phenotypes and Risk for Serious Mental Disorders in Young People: Need for Care Precedes Traditional Diagnoses in Mood and Psychotic Disorders
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P otentially severe and persistent or recurrent mental disorders pose the major threat to the health, happiness, and productivity of young people as they emerge from childhood to approach the threshold of adult life.The World Economic Forum has recently revealed that mental disorders now equal cardiovascular diseases (CVDs) as the major threat among noncommunicable diseases to the gross domestic product of modern economies.1 This is due largely to the timing in the life cycle of the onset of mental ill health, 2 with 75% of disorders emerging by age 25.Universal or primary prevention is the ultimate solution and must be actively researched and pursued where it works, though it is difficult to assemble solid evidence for this. 3 Where primary prevention is still out of reach (and the severe mood and psychotic disorders is one such domain), given we have a range of effective treatment strategies in psychiatry, there are 2 alternative pathways to actively follow.
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The need for care precedes the emergence of a traditional diagnostic picture or late macrophenotypes.
“The need for care precedes the emergence of a traditional diagnostic picture or late macrophenotypes. 196”
From The Lancet Psychiatry Commission on youth mental health (2024) · cites this paper as [196]
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- Authors
- McGorry, P.
- Affiliations
- The University of Melbourne (AU)
- Corresponding author
- McGorry, Patrick
- ORCID
- McGorry, Patrick
- Venue
- The Canadian Journal of Psychiatry
- Publisher
- SAGE Publications
- Published
- 2013-01
- Volume
- 58
- Issue
- 1
- Pages
- 19-21
- ISSN
- 0706-7437 (ISSN-L)
- 1497-0015
- OpenAlex
- W78661555
- Cited by
- 41
- References
- 20
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 2 · 2023: 3 · 2022: 3 · 2021: 3 · 2020: 3 · 2019: 5 · 2018: 2 · 2017: 1 · 2016: 1 · 2015: 3 · 2014: 9 · 2013: 1
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The Canadian Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Eli Lilly and Company
- Pfizer
- Medical Research Council
- National Health and Medical Research Council (566529)
- National Medical Research Council
- Cilag
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Keywords
- severe mental illness, youth, mood disorders, psychosis, primary prevention, early intervention, non-communicable diseases
- MeSH terms
- Humans, Psychotic Disorders, Schizotypal Personality Disorder, Prodromal Symptoms
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