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Cited by 275Circadian rhythm and melatoninGenetics, Aging, and Longevity in Model OrganismsSleep and Work-Related Fatigue

The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.

The Significance of Circadian Organization for Longevity in the Golden Hamster

Hurd, Mark W., Ralph, Martin R.·1998·Journal of Biological Rhythms
DOI 10.1177/074873098129000255
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Abstract

While functional roles for biological clocks have been demonstrated in organisms throughout phylogeny, the adaptive advantages of circadian organization per se are largely matters of conjecture. It is generally accepted, though without direct experimental evidence, that organisms derive primary benefits from the temporal organization of their physiology and behavior, as well as from the anticipation of daily changes in their environment and their own fluctuating physiological requirements. However, the consequences of circadian dysfunction that might demonstrate a primary adaptive advantage and explain the natural origins and apparent ubiquity of circadian systems have not been documented. The authors report that longevity in hamsters is decreased with a noninvasive disruption of rhythmicity and is increased in older animals given suprachiasmatic implants that restore higher amplitude rhythms. The results substantiate the importance of the temporal organization of physiology and behavior provided by the circadian clock to the health and longevity of an organism.

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Crossref · 10.1177/074873098129000255

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Citations

Cites

Show all 33 references

Research works printed but not linked: 7

  1. Brock, 1991, J Am Psychiatr Assoc, 39, 74
  2. Cai A, 1997, Am J Physiol, 272, R422
  3. Halberg and Cadotte, 1975, Chronobiologia, 2, 26
  4. Hurd MW (1996) Pacemaker-pacemaker communication in the mammalian circadian system. PhD dissertation, University of Toronto.
  5. Hurd MW, 1995, Am J Physiol, 269, R958
  6. Kripke DF, 1978, Biol Psychiat, 13, 335
  7. Minors DS, 1987, Aviation Med Quart, 1, 9

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Metadata

Authors
Hurd, M. W., & Ralph, M. R.
Affiliations
  • University of Houston (US)
  • University of Toronto (CA)
ORCID
Venue
Journal of Biological Rhythms
Publisher
SAGE Publications
Published
1998-10
Volume
13
Issue
5
Pages
430-436
ISSN
  • 0748-7304 (ISSN-L)
  • 1552-4531
DOI
10.1177/074873098129000255
OpenAlex
W1975982492
Cited by
275
References
33
Citations by year
2026: 7 · 2025: 2 · 2024: 17 · 2023: 18 · 2022: 9 · 2021: 14 · 2020: 20 · 2019: 15 · 2018: 6 · 2017: 11 · 2016: 9 · 2015: 18 · 2014: 10 · 2013: 15 · 2012: 10
FWCI
1.45
Type
journal article
Language
en
Open access
closed
Licence
journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)
Locations
  • Journal of Biological Rhythms (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Natural Sciences
  • National Institute on Aging
Topics
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Aging › Genetics, Aging, and Longevity in Model Organisms
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
Keywords
circadian clock, longevity, golden hamster, suprachiasmatic nucleus, circadian rhythm disruption, aging
MeSH terms
Aging, Animals, Circadian Rhythm, Environment, Cricetinae, Longevity, Mesocricetus, Motor Activity, Suprachiasmatic Nucleus, Fetal Tissue Transplantation

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