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Cited by 374

The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.

Iron Deficiency Anemia

Open access
Clark, Susan F.·2008·Nutrition in Clinical Practice

Abstract

The most severe consequence of iron depletion is iron deficiency anemia (IDA), and it is still considered the most common nutrition deficiency worldwide. Although the etiology of IDA is multifaceted, it generally results when the iron demands by the body are not met by iron absorption, regardless of the reason. Individuals with IDA have inadequate intake, impaired absorption or transport, physiologic losses associated with chronological or reproductive age, or chronic blood loss secondary to disease. In adults, IDA can result in a wide variety of adverse outcomes including diminished work or exercise capacity, impaired thermoregulation, immune dysfunction, GI disturbances, and neurocognitive impairment. In addition, IDA concomitant with chronic kidney disease or congestive heart failure can worsen the outcome of both conditions. In this review, the prevalence of IDA related to confounding medical conditions will be described along with its diverse etiologies. Distinguishing IDA from anemia of chronic disease using hematologic measures is reviewed as well. In addition, current diagnostic strategies that are inclusive of clinical presentation, biochemical tests, and differential diagnosis will be outlined, followed by a discussion of treatment modalities and future research recommendations.

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Crossref · 10.1177/0884533608314536

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Metadata

Authors
Clark, S. F.
Venue
Nutrition in Clinical Practice
Publisher
Wiley
Published
2008-04
Volume
23
Issue
2
Pages
128-141
ISSN
  • 0884-5336 (ISSN-L)
  • 1941-2452
OpenAlex
W3023029731
Cited by
374
References
10
FWCI
10.30
Type
journal article
Language
en
Open access
bronze

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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