Prospective study on cost-effectiveness of home-based motor assessment in Parkinson’s disease
Abstract
Introduction: Treatment adjustments in Parkinson’s disease (PD) are in part dependent on motor assessments. The aim of this study was to evaluate the cost-effectiveness of home-based motor monitoring plus standard in-office visits versus in-office visits alone in patients with advanced PD. Methods: The procedures consisted of a prospective, one-year follow-up, randomized, case-control study. A total of 40 patients with advanced PD were randomized into two groups: 20 patients underwent home-based motor monitoring by using wireless motion sensor technology, while the other 20 patients had in-office visits. Motor and non-motor symptom severities, quality of life, neuropsychiatric symptoms, and comorbidities were assessed every four months. Direct costs were assessed using a standardized questionnaire. Cost-effectiveness was assessed using the incremental cost-effectiveness ratio (ICER). Results: Both groups of PD patients were largely comparable in their clinical and demographic variables at baseline; however, there were more participants using levodopa-carbidopa intestinal gel in the home-based motor monitoring group. There was a trend for lower Unified Parkinson’s Disease Rating Scale functional status (UPDRS II) scores in the patients monitored at home compared to the standard clinical follow-up ( p = 0.06). However, UPDRS parts I, III, IV and quality-adjusted life-years scores were similar between both groups. Home-based motor monitoring was cost-effective in terms of improvement of functional status, motor severity, and motor complications (UPDRS II, III; IV subscales), with an ICER/UPDRS ranging from €126.72 to €701.31, respectively. Discussion: Home-based motor monitoring is a tool which collects cost-effective clinical information and helps augment health care for patients with advanced PD.
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Cubo et al. reported a trend of lower PD functional status (UPDRS I) in patients on home-based monitoring compared to patients in standard in-office visits (P = 0.06).
“In Spain, Cubo et al. [34] reported a trend of lower PD functional status (the Unified Parkinson’s Disease Rating Scale, UPDRS I) in patients on home-based monitoring compared to patients in standard in-office visits (P = 0.06), while other outcomes (measured by UPDRS II, III, IV subscales) and HRQoL in PD did not show statistically significant differences between the intervention and control”
From Effective behavioral intervention strategies using mobile health applications for chronic disease management: a systematic review (2018) · cites this paper as [34]
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- Authors
- Cubo, E., Mariscal, N., Solano, B., Becerra, V, Armesto, D., Calvo, S., Arribas, J., Seco, J., Martinez, A., Zorrilla, L., & Heldman, D.
- Affiliations
- Hospital Universitario de Burgos (ES)
- Centro Servicios Avanzados, Burgos, Spain
- Great Lakes NeuroTechnologies (United States) (US)
- Corresponding author
- Cubo, E
- Venue
- Journal of Telemedicine and Telecare
- Publisher
- SAGE Publications
- Published
- 2016-07-08
- Volume
- 23
- Issue
- 2
- Pages
- 328-338
- ISSN
- 1357-633X (ISSN-L)
- 1758-1109
- OpenAlex
- W2310365250
- Cited by
- 45
- References
- 33
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 2 · 2023: 5 · 2022: 7 · 2021: 6 · 2020: 7 · 2019: 3 · 2018: 4 · 2017: 3 · 2016: 1
- FWCI
- 2.76
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Telemedicine and Telecare (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Allergan
- Topics
- Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Health Sciences › Medicine › Neurology › Neurological disorders and treatments
- Keywords
- Parkinson's disease, cost-effectiveness, advanced Parkinson's disease, motor complications, remote patient monitoring, quality-adjusted life years
- MeSH terms
- Aged, Cost-Benefit Analysis, Female, Humans, Male, Monitoring, Physiologic, Parkinson Disease, Prospective Studies, Case-Control Studies, Telemedicine, Monitoring, Ambulatory
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