Mobile health (mHealth) for headache disorders: A review of the evidence base
Abstract
The aim of this review was to explore and summarise the evidence base for using mobile apps for the management of headache disorders. PubMed, Web of Science, Embase and Scopus were searched for studies reporting the use of mobile health applications (apps) for managing headache disorders. Different combinations of keywords for mobile health, smartphone and headache were used for electronic search. Six studies (two journal papers and four conference papers) met the inclusion criteria and were reviewed. All of the reviewed studies were categorised as the lowest level (level IV) of evidence according to the National Health and Medical Research Council (NHMRC) hierarchy of evidence. The results of the studies demonstrated the feasibility and acceptability of a few mobile apps for headache in very limited settings, and indicated that these apps can be effective tools for identifying trigger factors of migraine, improving self-management of headache disorders, and mediating the interactions between headache sufferers and their treating doctors. The role of participatory research and involvement of patients and clinicians in the development of such apps was also highlighted. Despite the availability of numerous mobile apps for headache disorders, the evidence base to support their effectiveness and clinical safety is very weak. The current literature indicates that mobile apps have the potential for improving the care of headache sufferers, but this is yet to be proven by adequately designed studies.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Evidence of the effectiveness of app-based behavioral interventions for managing headaches remains weak.
“However, evidence of the effectiveness of app-based behavioral interventions for managing headaches remains weak [44,47].”
Evidence on the effectiveness of mobile interventions for headaches is limited, despite their wide availability.
“Evidence on the effectiveness of mobile interventions for headaches is limited, despite their wide availability [47].”
Cites
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823 · see citing works
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & The PRISMA Group (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000097 · Cited by 64,042 · see citing works
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
(2009) · PubMed Central · Cited by 44,859 · see citing works
Free, C., Phillips, G., Watson, L., Galli, L., Felix, L., Edwards, P., Patel, V., & Haines, A. (2013) · PLoS Medicine · doi:10.1371/journal.pmed.1001363 · Cited by 1,187 · see citing works
A Guide to the Development, Implementation and Evaluation of Clinical Practice Guidelines
(1999) · PsycEXTRA Dataset · doi:10.1037/e508692012-001 · Cited by 531 · see citing works
Headache disorders are third cause of disability worldwide
Steiner, T. J., Birbeck, G. L., Jensen, R., Katsarava, Z., Stovner, L. J., & Martelletti, P. (2015) · The Journal of Headache and Pain · doi:10.1186/s10194-015-0544-2 · Cited by 262 · see citing works
Analysis of Trigger Factors in Episodic Migraineurs Using a Smartphone Headache Diary Applications
Park, J., Chu, M. K., Kim, J.-M., Park, S.-G., & Cho, S. (2016) · PLoS ONE · doi:10.1371/journal.pone.0149577 · Cited by 139 · see citing works
The regulation of mobile medical applications
Yetisen, A. K., Martinez-Hurtado, J. L., Vasconcellos, F. D. C., Simsekler, M. C. E., Akram, M. S., & Lowe, C. R. (2014) · Lab on a Chip · doi:10.1039/c3lc51235e · Cited by 115 · see citing works
Commercially Available Mobile Phone Headache Diary Apps: A Systematic Review
Hundert, A. S., Huguet, A., McGrath, P. J., Stinson, J., & Wheaton, M. (2014) · JMIR mhealth and uhealth · doi:10.2196/mhealth.3452 · Cited by 103 · see citing works
Diaries and Calendars for Migraine. A Review
Nappi, G., Jensen, R., Nappi, R. E., et al. (2006) · Cephalalgia · doi:10.1111/j.1468-2982.2006.01155.x · Cited by 83 · see citing works
Medical Application Use and the Need for Further Research and Assessment for Clinical Practice
Misra, S. K., Lewis, T., & Aungst, T. D. (2013) · JAMA Dermatology · doi:10.1001/jamadermatol.2013.606 · Cited by 59 · see citing works
Stinson, J., Huguet, A., McGrath, P. J., Rosenbloom, B. N., Soobiah, C., White, M., & Coburn, G. (2013) · Pain Research and Management · doi:10.1155/2013/369541 · Cited by 33 · see citing works
Huguet, A., McGrath, P. J., Wheaton, M., Mackinnon, S. P., Rozario, S., Tougas, M. E., Stinson, J., & MacLean, C. (2015) · JMIR mhealth and uhealth · doi:10.2196/mhealth.3879 · Cited by 30 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Behavioral Interventions for Migraine
Pérez-Muñoz, A., Buse, D. C., & Andrasik, F. (2019) · Neurologic Clinics · doi:10.1016/j.ncl.2019.07.003 · Cited by 58 · see citing works
An update on behavioral treatments in migraine - current knowledge and future options
Kropp, P., Meyer, B., Meyer, W., & Dresler, T. (2017) · Expert Review of Neurotherapeutics · doi:10.1080/14737175.2017.1377611 · Cited by 37 · see citing works
Ulrich, S., Gantenbein, A. R., Zuber, V., Von Wyl, A., Kowatsch, T., & Künzli, H. (2024) · Journal of Medical Internet Research · doi:10.2196/50132 · Cited by 36 · see citing works
“Evidence on the effectiveness of mobile interventions for headaches is limited, despite their wide availability [47].”
De Brouwer, M., Vandenbussche, N., Steenwinckel, B., Stojchevska, M., Van Der Donckt, J., Degraeve, V., Vaneessen, J., De Turck, F., Volckaert, B., Boon, P., et al. (2022) · BMC Medical Informatics and Decision Making · doi:10.1186/s12911-022-01813-w · Cited by 17 · see citing works
- Authors
- Mosadeghi-Nik, M., Askari, M. S., & Fatehi, F.
- Affiliations
- Tehran University of Medical Sciences (IR)
- Commonwealth Scientific and Industrial Research Organisation (AU)
- Corresponding author
- Askari, Marzyeh S
- Venue
- Journal of Telemedicine and Telecare
- Publisher
- SAGE Publications
- Published
- 2016-10-30
- Volume
- 22
- Issue
- 8
- Pages
- 472-477
- ISSN
- 1357-633X (ISSN-L)
- 1758-1109
- OpenAlex
- W2542876380
- Cited by
- 54
- References
- 13
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 4 · 2023: 5 · 2022: 7 · 2021: 5 · 2020: 10 · 2019: 7 · 2018: 10 · 2017: 1
- FWCI
- 11.16
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Telemedicine and Telecare (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
- Health Sciences › Medicine › Psychiatry and Mental health › Migraine and Headache Studies
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Keywords
- mobile health, headache disorders, migraine, mobile health apps, migraine triggers, patient-clinician interaction, participatory research, app development, feasibility and acceptability, evidence base
- MeSH terms
- Humans, Treatment Outcome, Telemedicine, Evidence-Based Medicine, Headache Disorders, Mobile Applications
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review