Cited by 82Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatmentsAging and Gerontology Research

Correlates of personal concerns about developing Alzheimer's disease among middle-aged persons

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Cutler, Stephen J., Hodgson, Lynne G.·2001·American Journal of Alzheimer's Disease & Other Dementias®

Abstract

We examine correlates of personal concerns about developing Alzheimer's disease (AD) among (1) adult children, 40 to 60 years of age, who have a living pare n t with a diagnosis of probable AD (N = 108), and (2) a matched comparison group of persons with no parental history of AD (N = 150). Using stepwise regression, predictors measuring subjective perceptions of memory functioning, overall family history of AD, knowledge of AD, and sociodemographic characteristics were entered into models for the total sample and each of the subsamples. The results indicate that worries about memory functioning play a consistent role in personal concerns about developing AD across both groups, but that additional pathways to personal concerns differ among individuals having and not having a parent with AD.

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Crossref · 10.1177/153331750101600604

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  • Family history of dementia is a strong predictor of ADRD diagnosis, particularly for Alzheimer's disease.

    “Besides age, family history of dementia has been acknowledged as a strong predictor of ADRD diagnosis, particularly for AD (Cutler & Hodgson, 2001; Ostergren, Heeringa, Leon, Connell, & Roberts, 2017; Roberts & Connell, 2000).”

    From Correlates of dementia-related anxiety: self-perceived dementia risk and ageism (2020) · cites this paper as Cutler & Hodgson, 2001

    The Discussion (page not available in our copy) says genetic risk for AD is higher among first-degree relatives. But this study examines concern about developing AD, not whether family history strongly predicts an ADRD diagnosis; it also does not establish the claim for dementias beyond AD. (LLM, conf=0.87)

    Experimental — accuracy not yet measured
  • Multiple studies have found that people with family history of Alzheimer's disease and/or caregiving experience report greater fear of developing Alzheimer's disease.

    “For instance, multiple studies have found that those with family history of AD (Cutler & Hodgson, 2001; Ostergren, Heeringa, Leon, Connell, & Roberts, 2017; Roberts & Connell, 2000) and/or experience with caregiving for someone with AD (Cantegreil-Kallen & Pin, 2012; Suhr & Kinkela, 2007), report greater fear of developing AD in the future.”

    From Correlates of dementia-related anxiety: self-perceived dementia risk and ageism (2020) · cites this paper as Cutler & Hodgson, 2001

  • The finding of no significant difference in dementia-related anxiety by genetic ADRD exposure is inconsistent with prior literature that family history of AD and caregiving for someone with AD are associated with greater dementia-related anxiety.

    “The lack of significant difference in DRA between those with and without genetic ADRD exposure is inconsistent with previous literature showing that having a family member with AD (Cutler & Hodgson, 2001; Ostergren et al., 2017; Roberts & Connell, 2000) and caregiving for someone with AD (Cantegreil-Kallen & Pin, 2012; Suhr & Kinkela, 2007) are associated with greater levels of DRA.”

    From Correlates of dementia-related anxiety: self-perceived dementia risk and ageism (2020) · cites this paper as Cutler & Hodgson, 2001

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Cites

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Research works printed but not linked: 2

  1. Hodgson L, Cutler S: Anticipatory dementia and well-being. American Journal of Alzheimer's Disease. 1997; 12(2): 62-66.
  2. Herrmann D: Questionnaires about memory. In: Harris J, Morris P (eds.): Everyday Memory, Actions, and Absentmindedness. New York: Academic Press, 1984: 133-151.

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Authors
Cutler, S. J., & Hodgson, L. G.
Affiliations
  • University of Vermont (US)
  • Quinnipiac University (US)
Venue
American Journal of Alzheimer's Disease & Other Dementias®
Published
2001-11
Volume
16
Issue
6
Pages
335-343
ISSN
  • 0888-4897 (ISSN-L)
  • 1533-3175
  • 1938-2731
OpenAlex
W1965746358
Cited by
82
References
36
Citations by year
2026: 3 · 2025: 4 · 2024: 3 · 2023: 2 · 2022: 2 · 2021: 5 · 2020: 9 · 2019: 4 · 2018: 7 · 2017: 5 · 2016: 7 · 2015: 6 · 2014: 6 · 2013: 2 · 2012: 2
FWCI
0.86
Type
journal article
Language
en
Open access
Locations
  • American Journal of Alzheimer s Disease & Other Dementias® (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
Alzheimer's Association (IIRG-98-016)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
  • Social Sciences › Psychology › Neuropsychology and Physiological Psychology › Aging and Gerontology Research
Keywords
Alzheimer's disease, personal concerns, family history of Alzheimer's disease, middle-aged adults, sociodemographic factors
MeSH terms
Adult, Aged, Aged, 80 and over, Alzheimer Disease, Attitude to Health, Cognition Disorders, Female, Humans, Male, Middle Aged

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