Hypochlorous Acid and Taurine-N-Monochloramine in Periodontal Diseases

Protein kinase C signaling and oxidative stress

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Glutathione in gingival crevicular fluid and its relation to local antioxidant capacity in periodontal health and disease

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Two Vicinal Cysteines Confer a Peculiar Redox Regulation to Low Molecular Weight Protein Tyrosine Phosphatase in Response to Platelet-derived Growth Factor Receptor Stimulation

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Taurine Chloramine Inhibits Inducible Nitric Oxide Synthase and TNF-α Gene Expression in Activated Alveolar Macrophages: Decreased NF-κB Activation and IκB Kinase Activity

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Hypochlorous Acid Generated by Myeloperoxidase Modifies Adjacent Tryptophan and Glycine Residues in the Catalytic Domain of Matrix Metalloproteinase-7 (Matrilysin)

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Cysteine Proteases of Porphyromonas Gingivalis

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Oxidation of IκBα at Methionine 45 Is One Cause of Taurine Chloramine-induced Inhibition of NF-κB Activation

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T he R ole of A cquired I mmunity and P eriodontal D isease P rogression

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Reassessment of the microbicidal activity of reactive oxygen species and hypochlorous acid with reference to the phagocytic vacuole of the neutrophil granulocyte

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Hypochlorous acid and chloramines increase endothelial permeability: possible involvement of cellular zinc

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Glutathione Oxidation by Hypochlorous Acid in Endothelial Cells Produces Glutathione Sulfonamide as a Major Product but Not Glutathione Disulfide

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Hypochlorous Acid Stimulation of the Mitogen-Activated Protein Kinase Pathway Enhances Cell Survival

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Taurine Chloramine Inhibits Lymphocyte Proliferation and Decreases Cytokine Production in Activated Human Leukocytes

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Activation of Nuclear Factor- κ B Transcriptional Activity in Airway Epithelial Cells by Thioredoxin but Not by N-Acetyl-Cysteine and Glutathione

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Antimicrobial and cytotoxic activity of hypochlorous acid: interactions with taurine and nitrite

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Oxidized alpha2-macroglobulin (alpha2M) differentially regulates receptor binding by cytokines/growth factors: implications for tissue injury and repair mechanisms in inflammation.

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Complement Activation by Myeloperoxidase Products Released from Stimulated Human Polymorphonuclear Leukocytes

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Different effects of hypochlorous acid on human neutrophil metalloproteinases: Activation of collagenase and inactivation of collagenase and gelatinase

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Oxidized α2-Macroglobulin (α2M) Differentially Regulates Receptor Binding by Cytokines/Growth Factors: Implications for Tissue Injury and Repair Mechanisms in Inflammation

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Taurine chloramine modulates cytokine production by human peripheral blood mononuclear cells.

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Thioredoxin Inhibits Tumor Necrosis Factor- or Interleukin-1-Induced NF- κ B Activation at a Level Upstream of NF- κ B-Inducing Kinase

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On the Oxidation of Cytochrome c by Hypohalous Acids

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Taurine Chloramine Inhibits the Production of Superoxide Anion, IL-6 and IL-8 in Activated Human Polymorphonuclear Leukocytes

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Selective inhibition of cyclooxygenase 2–generated prostaglandin E2 synthesis in rheumatoid arthritis synoviocytes by taurine chloramine

Kontny, E., Rudnicka, W., Kowalczewski, J. B., Marcinkiewicz, J., & Maśliński, W. (2003) · Arthritis & Rheumatism · doi:10.1002/art.10975 · Cited by 33 · see citing works

Growth-altering effects of sodium hypochlorite in cultured human dermal fibroblasts

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Hypochlorous Acid Activates Tyrosine Phosphorylation Signal Pathways Leading to Calcium Signaling and TNF α Production

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Chemical modification and 1H‐NMR studies on the receptor‐binding region of human interleukin 6

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Differential effects of chlorination of bacteria on their capacity to generate NO, TNF-alpha and IL-6 in macrophages.

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Uptake of Taurine and Taurine Chloramine in Murine Macrophages and their Distribution in Mice with Experimental Inflammation

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Taurine Chloramine Inhibits Production of Inflammatory Mediators and iNOS Gene Expression in Alveolar Macrophages; a Tale of Two Pathways: Part I, NF-κB Signaling

Quinn, M. R., Barua, M., Liu, Y., & Serban, V. (2003) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-0077-3_42 · Cited by 22 · see citing works

Anti-inflammatory Activities of Taurine Chloramine

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Anti-inflammatory activities of taurine chloramine: implication for immunoregulation and pathogenesis of rheumatoid arthritis.

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Inhibition of Collagenase Activity by N‐Chlorotaurine, a Product of Activated Neutrophils

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Taurine Chloramine Attenuates the Hydrolytic Activity of Matrix Metalloproteinase-9 in LPS-Activated Murine Peritoneal Macrophages

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Myeloperoxidase-catalyzed chlorination of histamine by stimulated neutrophils

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Production of Inflammatory Mediators by Activated C6 Cells Is Attenuated by Taurine Chloramine Inhibition of NF-κB Activation

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Negative chemotaxis inCytophaga johnsonae

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The role of reactive oxygen and antioxidant species in periodontal tissue destruction

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Taurine and Inflammatory Diseases

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N-chlorotaurine, a natural antiseptic with outstanding tolerability

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Inorganic Chemistry of Defensive Peroxidases in the Human Oral Cavity

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Naked-eye visible and fluorometric dual-signaling chemodosimeter for hypochlorous acid based on water-soluble p-methoxyphenol derivative

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A mitochondria-targeted fluorescent probe based on fluorescein derivative for detection of hypochlorite in living cells

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Effectiveness of Hypochlorous Acid to Reduce the Biofilms on Titanium Alloy Surfaces in Vitro

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The role of hypochlorous acid as one of the reactive oxygen species in periodontal disease

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Neutrophil Collagenase, Gelatinase, and Myeloperoxidase in Tears of Patients with Stevens-Johnson Syndrome and Ocular Cicatricial Pemphigoid

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Status Report on Topical Hypochlorous Acid: Clinical Relevance of Specific Formulations, Potential Modes of Action, and Study Outcomes.

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Gingival bleeding on probing: relationship to change in periodontal pocket depth and effect of sodium hypochlorite oral rinse

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Role of taurine, its haloamines and its lncRNA TUG1 in both inflammation and cancer progression. On the road to therapeutics? (Review)

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Effect of dentin pretreatment with mild acidic HOCl solution on microtensile bond strength and surface pH

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Host modulation therapy: An indispensable part of perioceutics

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Effect of smear layer deproteinizing on resin–dentine interface with self-etch adhesive

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Elevated Neutrophil Elastase in Tears of Ocular Graft-Versus-Host Disease Patients

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Effect of pretreatment with mildly acidic hypochlorous acid on adhesion to caries‐affected dentin using a self‐etch adhesive

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Real‐Time Noninvasive Monitoring of In Vivo Inflammatory Responses using a pH Ratiometric Fluorescence Imaging Probe

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A thiocoumarin-based fluorescent probe for detection of hypochlorite with high selectivity over other typical desulfurizing agents (Hg2+/Ag+)

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Metabolic phenotyping of saliva to identify possible biomarkers of periodontitis using proton nuclear magnetic resonance

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Effect of smear layer deproteinization on bonding of self-etch adhesives to dentin: a systematic review and meta-analysis

Alshaikh, K. H., Hamama, H. H. H., & Mahmoud, S. H. (2018) · Restorative Dentistry & Endodontics · doi:10.5395/rde.2018.43.e14 · Cited by 39 · see citing works

Hypochlorous Acid: From Innate Immune Factor and Environmental Toxicant to Chemopreventive Agent Targeting Solar UV-Induced Skin Cancer

Snell, J. A., Jandova, J., & Wondrak, G. T. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.887220 · Cited by 37 · see citing works

Metallic Implants for Biomedical Applications

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In vitro cytotoxicity and antibacterial activity of hypochlorous acid antimicrobial agent

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Small Molecular, Macromolecular, and Cellular Chloramines React with Thiocyanate To Give the Human Defense Factor Hypothiocyanite

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Radiation protection following nuclear power accidents: a survey of putative mechanisms involved in the radioprotective actions of taurine during and after radiation exposure.

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Molecular engineering of a dual emission near-infrared ratiometric fluorophore for the detection of pH at the organism level

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Topical Hypochlorous Acid (HOCl) as a Potential Treatment of Pruritus

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Mechanism and risk factors of oral biofilm formation

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Smear layer deproteinization with NaOCl and HOCl: Do application/wash-out times affect dentin bonding of one-step self-etch adhesives?

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Rhodol Derivatives as Selective Fluorescent Probes for the Detection of HgII Ions and the Bioimaging of Hypochlorous Acid

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A Highly Sensitive Fluorescent Probe for HClO and Its Application in Live Cell Imaging

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The Efficacy Of Four Cavity Disinfectant Solutions And Two Different Types Of Laser On The Micro-Shear Bond Strength Of Dentin Adhesives

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Multimodal Molecular Imaging Demonstrates Myeloperoxidase Regulation of Matrix Metalloproteinase Activity in Neuroinflammation

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Heme oxygenase-1 participates in the anti-inflammatory activity of taurine chloramine

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Effect of N-chlorotaurine mouth rinses on plaque regrowth and plaque vitality

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Comparison of taurine chloramine and taurine bromamine effects on rheumatoid arthritis synoviocytes

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Differential effects of taurine treatment and taurine deficiency on the outcome of renal ischemia reperfusion injury

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Sensing Hypochlorite or pH variations in live cells and zebrafish with a novel dual-functional ratiometric and colorimetric chemosensor

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Modifications of IL-6 by Hypochlorous Acids: Effects on Receptor Binding

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Multifunctional chemosensor for tracing Ga(III), hypochlorite and pH change with bioimaging in living cells, Pseudomonas aeruginosa and Zebrafish

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Insights into Intra Periodontal Pocket Pathogenesis, Treatment, In Vitro-In Vivo Models, Products and Patents, Challenges and Opportunity

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Ácido Hipocloroso: una Nueva Alternativa como Agente Antimicrobiano y para la Proliferación Celular para Uso en Odontología

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Non-invasive Characterization of Immune Responses to Biomedical Implants

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