Peroxisomes in dorsal root ganglia
Open accessAbstract
Bodies with the morphologic and cytochemical characteristics of peroxisomes have been identified in the satellite and Schwann cells of rat dorsal root ganglia. They are membrane-delimited, round or oval structures which contain a moderately electron-dense matrix but lack a crystalline core. On incubation of the tissue in a cytochemical medium for demonstration of peroxisomes, these bodies show heavy deposits of reaction product. The reaction is inhibited by heating the tissue or by incubation in the presence of aminotriazole or dichlorophenolindophenol. In tissue incubated for acid phosphatase activity the bodies are not reactive, although lysosomes show reaction product.
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In the rat PNS, peroxisomes were described in Schwann cells, dorsal root ganglion satellite cells, and less abundantly in neuronal somata.
“In the rat PNS, peroxisomes were described in Schwann cells, which represent the myelinating cells of the PNS, as well as in dorsal root ganglion satellite cells and, less abundantly, in neuronal somata [29].”
From Peroxisomes in brain development and function (2016) · cites this paper as [29]
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- Authors
- CITKOWITZ, E., & HOLTZMAN, E.
- Affiliations
- Columbia University (US)
- Venue
- Journal of Histochemistry & Cytochemistry
- Publisher
- SAGE Publications
- Published
- 1973-01
- Volume
- 21
- Issue
- 1
- Pages
- 34-41
- ISSN
- 0022-1554 (ISSN-L)
- 1551-5044
- OpenAlex
- W2099001561
- Cited by
- 49
- References
- 34
- Citations by year
- 2025: 1 · 2020: 1 · 2018: 2 · 2015: 1 · 2014: 1 · 2012: 1
- FWCI
- 4.02
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Histochemistry & Cytochemistry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular transport and secretion
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Redox biology and oxidative stress
- Health Sciences › Medicine › Anatomy › Medical and Biological Sciences
- Keywords
- peroxisomes, dorsal root ganglia, satellite cells, Schwann cells, peroxisomal matrix, dichlorophenolindophenol, acid phosphatase, lysosomes, rats
- MeSH terms
- Animals, Cells, Cultured, Endoplasmic Reticulum, Female, Ganglia, Spinal, Male, Microbodies, Microscopy, Electron, Organoids, Schwann Cells, Rats
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