The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.
Critical Fluctuations as an Early-Warning Signal for Sudden Gains and Losses in Patients Receiving Psychotherapy for Mood Disorders
Open accessAbstract
Whereas sudden gains and losses (large shifts in symptom severity) in patients receiving psychotherapy appear abrupt and hence may seem unexpected, hypotheses from complex-systems theory suggest that sudden gains and losses are actually preceded by certain early-warning signals (EWSs). We tested whether EWSs in patients’ daily self-ratings of the psychotherapeutic process predicted future sudden gains and losses. Data were collected from 328 patients receiving psychotherapy for mood disorders who completed daily self-ratings about their therapeutic process using the Therapy Process Questionnaire (TPQ). Sudden gains and losses were classified from the Problem Intensity scale of the TPQ. The other items of the TPQ were used to compute the EWSs. EWSs predicted an increased probability for sudden gains and losses in a 4-day predictive window. These results show that EWSs can be used for real-time prediction of sudden gains and losses in clinical practice.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“However, EMA data has also been successfully used to predict the development of symptoms within treatments [e.g., (42)].”
From Personalised depression forecasting using mobile sensor data and ecological momentary assessment (2022) · cites this paper as [42]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
R: A Language and Environment for Statistical Computing
R Core Team (2000) · doi:10.32614/r.manuals · Cited by 355,893
Fitting Linear Mixed-Effects Models Using lme4
Bates, D., Mächler, M., Bolker, B., & Walker, S. (2015) · Journal of Statistical Software · doi:10.18637/jss.v067.i01 · Cited by 86,835
Early-warning signals for critical transitions
Scheffer, M., Bascompte, J., Brock, W. A., Brovkin, V., Carpenter, S. R., Dakos, V., Held, H., van Nes, E. H., Rietkerk, M., & Sugihara, G. (2009) · Nature · doi:10.1038/nature08227 · Cited by 4,854
A Dynamic Systems Approach to the Development of Cognition and Action
Thelen, E., & Smith, L. B. (1994) · doi:10.7551/mitpress/2524.001.0001 · Cited by 3,470
A dynamic systems approach to the development of cognition and action
Thelen, E., & Smith, L. B. (1996) · Computers & Mathematics with Applications · doi:10.1016/s0898-1221(96)90021-8 · Cited by 3,454
Mediators and Mechanisms of Change in Psychotherapy Research
Kazdin, A. E. (2007) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.3.022806.091432 · Cited by 2,504 · cited 4×
“One central issue in the study of change processes in psychotherapy is the establishment of a timeline in individual change trajectories (i.e., a temporal relation between a hypothesized mechanism and a symptom severity measure; Kazdin, 2007).”
BackgroundMethodInfluentialAnticipating Critical Transitions
Scheffer, M., Carpenter, S. R., Lenton, T. M., Bascompte, J., Brock, W., Dakos, V., van de Koppel, J., van de Leemput, I. A., Levin, S. A., van Nes, E. H., et al. (2012) · Science · doi:10.1126/science.1225244 · Cited by 2,208
Haken, H. (1983) · Springer series in synergetics · doi:10.1007/978-3-642-88338-5 · Cited by 1,471
Lack of group-to-individual generalizability is a threat to human subjects research
Fisher, A. J., Medaglia, J. D., & Jeronimus, B. F. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1711978115 · Cited by 1,099
Critical slowing down as early warning for the onset and termination of depression
van de Leemput, I. A., Wichers, M., Cramer, A. O. J., Borsboom, D., Tuerlinckx, F., Kuppens, P., van Nes, E. H., Viechtbauer, W., Giltay, E. J., Aggen, S. H., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1312114110 · Cited by 816
Nonlinear Dynamics, Psychology and Life Sciences
Cecen, A. A. (2010) · Cited by 785
Understanding how and why psychotherapy leads to change
Kazdin, A. E. (2009) · Psychotherapy Research · doi:10.1080/10503300802448899 · Cited by 728 · cited 1×
“Although the beneficial effects of psychotherapy are firmly established, evidence-based explanations of how psychotherapy leads to change are lacking (Kazdin, 2009; Lorenzo-Luaces & DeRubeis, 2018).”
BackgroundSudden gains and critical sessions in cognitive-behavioral therapy for depression.
Tang, T. Z., & DeRubeis, R. J. (1999) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.67.6.894 · Cited by 684 · cited 1×
“…open materials, preregistered Received 10/16/18; Revision accepted 5/10/19 The most well-known discontinuous change patterns are sudden gains (abrupt changes toward lower symptom severity) and sudden losses (abrupt changes toward higher symptom severity; Lutz et al., 2013; Tang & DeRubeis, 1999).”
BackgroundMajor Depression as a Complex Dynamic System
Cramer, A. O. J., van Borkulo, C. D., Giltay, E. J., van der Maas, H. L. J., Kendler, K. S., Scheffer, M., & Borsboom, D. (2016) · PLoS ONE · doi:10.1371/journal.pone.0167490 · Cited by 599
Hayes, A. M., Laurenceau, J., Feldman, G. C., Strauss, J. L., & Cardaciotto, L. (2007) · Clinical Psychology Review · doi:10.1016/j.cpr.2007.01.008 · Cited by 573
Nonequilibrium phase transitions in coordinated biological motion: critical fluctuations
Kelso, J. A. S., Scholz, J. P., & Schöner, G. (1986) · Physics Letters A · doi:10.1016/0375-9601(86)90359-2 · Cited by 463
Critical Slowing Down as a Personalized Early Warning Signal for Depression
Wichers, M., Groot, P. C., & Psychosystems, E. G. (2016) · Psychotherapy and Psychosomatics · doi:10.1159/000441458 · Cited by 399
Moving From Static to Dynamic Models of the Onset of Mental Disorder
Nelson, B., McGorry, P. D., Wichers, M., Wigman, J. T. W., & Hartmann, J. (2017) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2017.0001 · Cited by 378
A complex network perspective on clinical science
Hofmann, S. G., Curtiss, J., & McNally, R. J. (2016) · Perspectives on Psychological Science · doi:10.1177/1745691616639283 · Cited by 366
Sudden gains and critical sessions in cognitive-behavioral therapy for depression
Tang, T. Z., & DeRubeis, R. (1999) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.67.6.894 · Cited by 284
Scholz, J. P., Kelso, J. A. S., & Schöner, G. (1987) · Physics Letters A · doi:10.1016/0375-9601(87)90038-7 · Cited by 260
Nonlinear Modeling of Time Series Using Multivariate Adaptive Regression Splines (MARS)
Lewis, P., & Stevens, J. G. (1991) · Journal of the American Statistical Association · doi:10.1080/01621459.1991.10475126 · Cited by 260
Early sudden gains in psychotherapy under routine clinic conditions: Practice-based evidence.
Stiles, W. B., Leach, C., Barkham, M., Lucock, M., Iveson, S., Shapiro, D. A., Iveson, M., & Hardy, G. E. (2003) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.71.1.14 · Cited by 220 · cited 1×
“Certain nonspecific treatment factors such as hope, positive expectations, and the therapeutic relationship have been associated with sudden gains (Lutz et al., 2013; Stiles et al., 2003).”
BackgroundDo early responders to psychotherapy maintain treatment gains?
Haas, E., Hill, R., Lambert, M., & Morrell, B. (2002) · Journal of Clinical Psychology · doi:10.1002/jclp.10044 · Cited by 220
The ups and downs of psychotherapy: Sudden gains and sudden losses identified with session reports
Lutz, W., Ehrlich, T., Rubel, J. A., Hallwachs, N., Röttger, M.-A., Jorasz, C., Mocanu, S., Vocks, S., Schulte, D., & Tschitsaz, A. (2012) · Psychotherapy Research · doi:10.1080/10503307.2012.693837 · Cited by 208
Timing is everything: Developmental psychopathology from a dynamic systems perspective☆
Granic, I. (2005) · Developmental Review · doi:10.1016/j.dr.2005.10.005 · Cited by 185
Lambert, M. J. (2005) · Journal of Clinical Psychology · doi:10.1002/jclp.20130 · Cited by 182
Disabuse of the drug metaphor: psychotherapy process-outcome correlations.
Stiles, W. B., & Shapiro, D. A. (1994) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.62.5.942 · Cited by 168
Dynamics of representational change: Entropy, action, and cognition.
Kelty‐Stephen, D. G., Dixon, J. A., & Isenhower, R. W. (2009) · Journal of Experimental Psychology Human Perception & Performance · doi:10.1037/a0014510 · Cited by 161
Kelly, M. A. R., Roberts, J. E., & Ciesla, J. A. (2004) · Behaviour Research and Therapy · doi:10.1016/j.brat.2004.06.002 · Cited by 151
Orden, G. C. V., Kloos, H., & Wallot, S. (2011) · Elsevier eBooks · doi:10.1016/b978-0-444-52076-0.50022-5 · Cited by 146
Schiepek, G. K., & Strunk, G. (2010) · Biological Cybernetics · doi:10.1007/s00422-009-0362-1 · Cited by 143
Self-citationSudden Gains in Cognitive Therapy for Depression: A Replication and Extension.
Hardy, G. E., Cahill, J., Stiles, W. B., Ispan, C., Macaskill, N. D., & Barkham, M. (2005) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.73.1.59 · Cited by 133
Real-Time Monitoring of Psychotherapeutic Processes: Concept and Compliance
Schiepek, G. K., Aichhorn, W., Gruber, M., Strunk, G., Bachler, E., & Aas, B. (2016) · Frontiers in Psychology · doi:10.3389/fpsyg.2016.00604 · Cited by 133
Self-citationA dynamic pattern theory of behavioral change
Schöner, G., & Kelso, J. A. S. (1988) · Journal of Theoretical Biology · doi:10.1016/s0022-5193(88)80273-x · Cited by 131
Sudden gains during therapy of social phobia.
Hofmann, S. G., Schulz, S. M., Meuret, A. E., Moscovitch, D. A., & Suvak, M. K. (2006) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.74.4.687 · Cited by 131
Gelo, O. C. G., & Salvatore, S. (2016) · Journal of Counseling Psychology · doi:10.1037/cou0000150 · Cited by 131
Hayes, A. M., & Strauss, J. L. (1998) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.66.6.939 · Cited by 127
Sudden gains and outcome: a broader temporal analysis of cognitive therapy for depression.
Busch, A. M., Kanter, J. W., Landes, S., & Kohlenberg, R. (2006) · The Behavior Therapist · doi:10.1016/j.beth.2005.04.002 · Cited by 96
Self-organization in psychotherapy: testing the synergetic model of change processes
Schiepek, G. K., Tominschek, I., & Heinzel, S. (2014) · Frontiers in Psychology · doi:10.3389/fpsyg.2014.01089 · Cited by 91
Self-citationIntegrative Psychotherapy: A Feedback-Driven Dynamic Systems Approach
Schiepek, G. K., Eckert, H., Aas, B., Wallot, S., & Wallot, A. (2015) · Hogrefe Publishing eBooks · doi:10.1027/00472-000 · Cited by 91
Self-citationWichers, M., Schreuder, M. J., Goekoop, R., & Groen, R. N. (2018) · Psychological Medicine · doi:10.1017/s0033291718002064 · Cited by 81
Olthof, M., Hasselman, F., Strunk, G., Aas, B., Schiepek, G. K., & Lichtwarck‐Aschoff, A. (2019) · Psychotherapy Research · doi:10.1080/10503307.2019.1633484 · Cited by 78
Self-citationNonlinear Modeling of Time Series Using Multivariate Adaptive Regression Splines (MARS)
Lewis, P., & Stevens, J. G. (1991) · Journal of the American Statistical Association · doi:10.2307/2290499 · Cited by 75
Lichtwarck‐Aschoff, A., Hasselman, F., Cox, R. F. A., Pepler, D. J., & Granic, I. (2012) · PubMed · Cited by 69
Self-citationComplexity and Nonlinear Dynamics in Psychotherapy
Schiepek, G. K. (2009) · European Review · doi:10.1017/s1062798709000763 · Cited by 67
Self-citationPattern destabilization and emotional processing in cognitive therapy for personality disorders
Hayes, A. M., & Yasinski, C. W. (2015) · Frontiers in Psychology · doi:10.3389/fpsyg.2015.00107 · Cited by 64
Lorenzo-Luaces, L., & DeRubeis, R. J. (2018) · Cognitive Therapy and Research · doi:10.1007/s10608-018-9893-x · Cited by 56
Heinzel, S., Tominschek, I., & Schiepek, G. K. (2014) · PubMed · Cited by 54
Self-citationReal-Time Monitoring of Non-linear Suicidal Dynamics: Methodology and a Demonstrative Case Report
Fartacek, C., Schiepek, G. K., Kunrath, S., Fartacek, R. R., & Plöderl, M. (2016) · Frontiers in Psychology · doi:10.3389/fpsyg.2016.00130 · Cited by 54
Self-citationA Dynamic Systems Approach to Clinical Case Formulation
Schiepek, G. K. (2003) · European Journal of Psychological Assessment · doi:10.1027//1015-5759.19.3.175 · Cited by 50
Self-citationInstabilities and phase transitions in human brain and behavior
Kelso (2010) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2010.00023 · Cited by 49
“Critical slowing down in depression” is a great idea that still needs empirical proof
Bos, E. H., & JONGE, P. D. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1323672111 · Cited by 47
Wucherpfennig, F., Rubel, J. A., Hollon, S. D., & Lutz, W. (2016) · Behaviour Research and Therapy · doi:10.1016/j.brat.2016.11.003 · Cited by 26
Der Therapie-Prozessbogen (TPB) – Faktorenstruktur und psychometrische Daten
Schiepek, G. K., Aichhorn, W., & Strunk, G. (2012) · Zeitschrift für psychosomatische Medizin und Psychotherapie · doi:10.13109/zptm.2012.58.3.257 · Cited by 25
Self-citation
Research works printed but not linked: 5
- Haken H., Schiepek G. (2010). Synergetik in der Psychologie: Selbstorganisation verstehen und gestalten [Synergetics in psychology: understanding and shaping self-organization] (corrected ed.). Göttingen, Germany: Hogrefe.
- 10.1016/j.cpr.2007.01.008.Change · DOI
- Heinzel S., 2014, Nonlinear Dynamics, Psychology, and Life Sciences, 18, 155
- Helmich M. A., 2019, Sudden gains and linear change predict better outcomes for depressed individuals in therapy
- World Health Organization, 1992, International statistical classification of diseases and related health problems, 10th revisions (ICD-10)
Cited by
Sorted by citations
Roefs, A., Fried, E. I., Kindt, M., Martijn, C., Elzinga, B., Evers, A. W. M., Wiers, R. W., Borsboom, D., & Jansen, A. (2022) · Behaviour Research and Therapy · doi:10.1016/j.brat.2022.104096 · Cited by 185
Studying Behaviour Change Mechanisms under Complexity
Heino, M. T. J., Knittle, K. P., Noone, C., Hasselman, F., & Hankonen, N. E. (2021) · Behavioral Sciences · doi:10.3390/bs11050077 · Cited by 161
Self-citationA complex systems approach to the study of change in psychotherapy
Hayes, A. M., & Andrews, L. A. (2020) · BMC Medicine · doi:10.1186/s12916-020-01662-2 · Cited by 149
A review of approaches and models in psychopathology conceptualization research
Eaton, N. R., Bringmann, L. F., Elmer, T., Fried, E. I., Forbes, M. K., Greene, A. L., Krueger, R. F., Kotov, R., McGorry, P. D., Mei, C., et al. (2023) · Nature Reviews Psychology · doi:10.1038/s44159-023-00218-4 · Cited by 171
Studying Mental Health Problems as Systems, Not Syndromes
Fried, E. I. (2022) · Current Directions in Psychological Science · doi:10.1177/09637214221114089 · Cited by 169
Metadata
- Authors
- Olthof, M., Hasselman, F., Strunk, G., van Rooij, M., Aas, B., Helmich, M. A., Schiepek, G., & Lichtwarck-Aschoff, A.
- Affiliations
- Radboud University Nijmegen (NL)
- TU Dortmund University (DE)
- Behavioural Science Institute, Radboud University
- LMU Klinikum (DE)
- University Medical Center Groningen (NL)
- Paracelsus Medical University (AT)
- Corresponding author
- Olthof, Merlijn
- Venue
- Clinical Psychological Science
- Publisher
- SAGE Publications
- Published
- 2019-09-24
- Volume
- 8
- Issue
- 1
- Pages
- 25-35
- ISSN
- 2167-7026 (ISSN-L)
- 2167-7034
- OpenAlex
- W2976346093
- Cited by
- 146
- References
- 53
- Citations by year
- 2026: 11 · 2025: 12 · 2024: 20 · 2023: 30 · 2022: 32 · 2021: 23 · 2020: 16 · 2019: 2
- FWCI
- 21.34
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Clinical Psychological Science (publishedVersion, cc-by-nc)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (publishedVersion, cc-by-nc)
- Open access LMU (Ludwid Maxmilian's Universitat Munchen) (submittedVersion, cc-by-nc)
- Radboud Repository (Radboud University) (submittedVersion)
- Radboud Repository (Radboud University) (submittedVersion, other-oa)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion, cc-by-nc)
- Funders
- h2020 european research council (ERC-CoG-2015; No 681466)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
- Physical Sciences › Environmental Science › Global and Planetary Change › Ecosystem dynamics and resilience
- Keywords
- early warning indicators, critical fluctuations, psychotherapy outcome prediction, mood disorders, therapeutic process, complexity theory
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review