The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Cellular localization of tyrosine hydroxylase by immunohistochemistry.
Open accessAbstract
The enzyme tyrosine hydroxylase (TH) was immunohistochemically localized by the peroxidase-antiperoxidase method in rat to chromaffin cells of the adrenal medulla, large neurons and small darkly staining cells of the superior cervical ganglia and noradrenergic and dopaminergic neurons in brain. As compared with the conjugated peroxidase or immunofluorescence techniques, the peroxidase-antiperoxidase method gave the most selective and specific cytoplasmic localization of TH antisera in every tissue examined. The peroxidase staining with the TH antisera was more intense in dopaminergic than in noradrenergic neurons of the central nervous system. While TH was visualized in cell bodies of both dopaminergic and noradrenergic neurons, it could only be detected in axons and terminals in the dopaminergic system. The perikarya of noradrenergic neurons could be distinguished from dopaminergic neurons by the immunohistochemical demonstration of the enzyme dopamine-beta-hydroxylase only in the former.
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Cites
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Stereotaxic mapping of the monoamine pathways in the rat brain
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Self-citationTyrosine hydroxylase in rat brain—cofactor requirements, regional and subcellular distribution
Coyle, J. T. (1972) · Biochemical Pharmacology · doi:10.1016/0006-2952(72)90006-8 · Cited by 303
ADENOHYPOPHYSIS: ULTRASTRUCTURAL CYTOCHEMISTRY A REVIEW
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Regulatory Properties of Soluble and Particulate Rat Brain Tyrosine Hydroxylase
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Immunohistochemical localization of three catecholamine synthesizing enzymes: aspects on methodology
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Cited by
Molecular Mechanisms and Clinical Implications of Reversible Protein S -Glutathionylation
Mieyal, J. J., Gallogly, M. M., Qanungo, S., Sabens, E. A., & Shelton, M. D. (2008) · Antioxidants & Redox Signaling · doi:10.1089/ars.2008.2089 · Cited by 523
Brain Enolases as Specific Markers of Neuronal and Glial Cells
Schmechel, D., Marangos, P. J., Zis, A. P., Brightman, M., & Goodwin, F. K. (1978) · Science · doi:10.1126/science.339349 · Cited by 461
Gaspar, P., Berger, B., Febvret, A., Vigny, A., & Henry, J. P. (1989) · Journal of Comparative Neurology · doi:10.1002/cne.902790208 · Cited by 395
Specht, L. A., Pickel, V. M., Joh, T. H., & Reis, D. J. (1981) · Journal of Comparative Neurology · doi:10.1002/cne.901990207 · Cited by 353
Self-citationLewis, D., Campbell, M., Foote, S., Goldstein, M., & Morrison, J. (1987) · The Journal of Neuroscience · doi:10.1523/jneurosci.07-01-00279.1987 · Cited by 325
Metadata
- Authors
- Pickel, V. M., Joh, T. H., Field, P. M., Becker, C. G., & Reis, D. J.
- Venue
- Journal of Histochemistry & Cytochemistry
- Publisher
- SAGE Publications
- Published
- 1975-01
- Volume
- 23
- Issue
- 1
- Pages
- 1-12
- ISSN
- 0022-1554 (ISSN-L)
- 1551-5044
- OpenAlex
- W2106528665
- Cited by
- 262
- References
- 19
- FWCI
- 4.23
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Pickel, V. M., Joh, T. H., Field, P. M., Becker, C. G., & Reis, D. J. (1975). Cellular localization of tyrosine hydroxylase by immunohistochemistry. Journal of Histochemistry & Cytochemistry. https://doi.org/10.1177/23.1.234988
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
