Educational Case: Ischemic Disorders of the Gut in Adult Patients
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The following fictional case is intended as a learning tool within the Pathology Competencies for Medical Education (PCME), a set of national standards for teaching pathology. These are divided into three basic competencies: Disease Mechanisms and Processes, Organ System Pathology, and Diagnostic Medicine and Therapeutic Pathology. For additional information, and a full list of learning objectives for all three competencies, see http://journals.sagepub.com/doi/10.1177/2374289517715040.1
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Iatrogenic intestinal ischemia can occur post-surgically, due to dislodgement of intravascular devices, and secondary to use of certain medications.
“Iatrogenic intestinal ischemia can occur post-surgically (abdominal aortic aneurysm surgery, colectomy, bypass surgery), due to dislodgement of intravascular devices, and secondary to use of certain medications–estrogen, digoxin, danazol, alosetron, pseudo ephedrine, vasopressin, Gold, psychotropic drugs, sumatriptan, serotoninergic agonists and anatagonists immunomodulators, laxatives and non-st”
From Ischemic bowel disease in 2021. (2021) · cites this paper as [8]
The ‘Major Causes of Ischemic Injury’ section says iatrogenic intestinal ischemia may occur after surgery or from medications. It attributes device-related ischemia specifically to dislodged polymer coatings on intravascular devices, not to dislodgement of the devices themselves. (LLM, conf=0.86)
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Cites
Epidemiology and Clinical Manifestations of Mucormycosis
Petrikkos, G. L., Skiada, A., Lortholary, O., Roilides, E., Walsh, T. J., & Kontoyiannis, D. P. (2012) · Clinical Infectious Diseases · doi:10.1093/cid/cir866 · Cited by 1,461 · see citing works
Wechalekar, A. D., Gillmore, J. D., & Hawkins, P. N. (2015) · The Lancet · doi:10.1016/s0140-6736(15)01274-x · Cited by 997 · see citing works
Nomenclature 2014: Amyloid fibril proteins and clinical classification of the amyloidosis
Sipe, J. D., Benson, M. D., Buxbaum, J. N., Ikeda, S.-I., Merlini, G., Saraiva, M. J., & Westermark, P. (2014) · Amyloid · doi:10.3109/13506129.2014.964858 · Cited by 507 · see citing works
Brandt, L. J., Feuerstadt, P., Longstreth, G. F., & Boley, S. J. (2015) · American Journal of Gastroenterology · doi:10.1038/ajg.2014.395 · Cited by 377 · see citing works
CT Diagnosis of Acute Mesenteric Ischemia from Various Causes
Furukawa, A., Kanasaki, S., Kono, N., Wakamiya, M., Tanaka, T., Takahashi, M., & Murata, K. (2009) · American Journal of Roentgenology · doi:10.2214/ajr.08.1138 · Cited by 300 · see citing works
Eosinophilic granulomatosis with polyangiitis ( C hurg– S trauss): state of the art
Vaglio, A., Buzio, C., & Zwerina, J. (2013) · Allergy · doi:10.1111/all.12088 · Cited by 283 · see citing works
Diagnosis and classification of granulomatosis with polyangiitis (aka Wegener's granulomatosis)
Lutalo, P., & D’Cruz, D. P. (2014) · Journal of Autoimmunity · doi:10.1016/j.jaut.2014.01.028 · Cited by 245 · see citing works
Escherichia coli O157:H7-associated colitis. A clinical and histological study of 11 cases.
Griffin, P. M., Olmstead, L. C., & Petras, R. E. (1990) · PubMed · doi:10.1016/0016-5085(90)91241-w · Cited by 245 · see citing works
The epidemiology of ischaemic colitis
Higgins, P., Davis, K. J., & Laine, L. (2004) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2004.01903.x · Cited by 235 · see citing works
Pathology Competencies for Medical Education and Educational Cases
Knollmann-Ritschel, B. E. C., Regula, D. P., Borowitz, M. J., et al. (2017) · Academic Pathology · doi:10.1177/2374289517715040 · Cited by 182 · see citing works
Flobert, C., Cellier, C., Berger, A., Ngo, A., Cuillerier, E., Landi, B., Marteau, P., Cugnenc, P.-H., & Barbier, J.-P. (2000) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2000.01644.x · Cited by 152 · see citing works
Current theories of pathogenesis and treatment of nonocclusive mesenteric ischemia
Wilcox, M. G., Howard, T. J., Plaskon, L. A., Unthank, J. L., & Madura, J. A. (1995) · Digestive Diseases and Sciences · doi:10.1007/bf02064966 · Cited by 142 · see citing works
Antineutrophil cytoplasmic antibodies (ANCA)
Radice, A., & Sinico, R. A. (2005) · Autoimmunity · doi:10.1080/08916930400022673 · Cited by 141 · see citing works
Freudenthaler, S., Hegenbart, U., Schönland, S. O., Behrens, H., Krüger, S., & Röcken, C. (2016) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/s00428-016-1916-y · Cited by 128 · see citing works
Sise, M. J. (2013) · Surgical Clinics of North America · doi:10.1016/j.suc.2013.10.012 · Cited by 118 · see citing works
The Colonic Pathology of Escherichia coli 0157
Kelly, J., Oryshak, A., Wenetsek, M., et al. (1990) · The American Journal of Surgical Pathology · doi:10.1097/00000478-199001000-00010 · Cited by 115 · see citing works
The changing face of polyarteritis nodosa and necrotizing vasculitis
Özen, S. (2017) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2017.68 · Cited by 100 · see citing works
A retrospective series of gut aspergillosis in haematology patients
Kazan, E., Maertens, J., Herbrecht, R., Weisser, M., Gachot, B., Vekhoff, A., Caillot, D., Raffoux, E., Fagot, T., Reman, O., et al. (2010) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2010.03310.x · Cited by 99 · see citing works
Microscopic polyangiitis: Advances in diagnostic and therapeutic approaches
Greco, A., VIRGILIO, A. D., Rizzo, M. I., Gallo, A., Magliulo, G., Fusconi, M., Ruoppolo, G., Tombolini, M., Turchetta, R., & VINCENTIIS, M. D. (2015) · Autoimmunity Reviews · doi:10.1016/j.autrev.2015.05.005 · Cited by 84 · see citing works
Iida, T., Yamano, H., & Nakase, H. (2017) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.13996 · Cited by 79 · see citing works
Histologic Features of Gastrointestinal Tract Biopsies in IgA Vasculitis (Henoch-Schönlein Purpura)
Louie, C. Y., Gomez, A. J., Sibley, R. K., et al. (2018) · The American Journal of Surgical Pathology · doi:10.1097/pas.0000000000001036 · Cited by 79 · see citing works
Update on Colon Ischemia: Recent Insights and Advances
Feuerstadt, P., & Brandt, L. J. (2015) · Current Gastroenterology Reports · doi:10.1007/s11894-015-0469-6 · Cited by 64 · see citing works
Blood supply to the human gastroduodenal mucosa with special reference to the ulcer-bearing areas.
Piasecki, C. (1974) · PubMed · Cited by 59 · see citing works
Inflammatory and infectious manifestations of immunodeficiency in the gastrointestinal tract
Panarelli, N. C., & Yantiss, R. K. (2018) · Modern Pathology · doi:10.1038/s41379-018-0015-9 · Cited by 59 · see citing works
Self-citationWinter, M., Tholey, A., Kristen, A. V., & Röcken, C. (2017) · PROTEOMICS · doi:10.1002/pmic.201700236 · Cited by 58 · see citing works
Chen, Y.-M., Hung, Y., Huang, C.-F., et al. (2013) · Journal of Microbiology Immunology and Infection · doi:10.1016/j.jmii.2013.01.011 · Cited by 56 · see citing works
Drug-induced injury in the gastrointestinal tract
Panarelli, N. C. (2014) · Seminars in Diagnostic Pathology · doi:10.1053/j.semdp.2014.02.007 · Cited by 39 · see citing works
Self-citationAida, J., Vieth, M. W., Ell, C., et al. (2011) · The American Journal of Surgical Pathology · doi:10.1097/pas.0b013e3182206c0e · Cited by 33 · see citing works
Suzuki, K. (2012) · Clinical and Experimental Nephrology · doi:10.1007/s10157-012-0684-5 · Cited by 28 · see citing works
Hydrophilic Polymer–associated Ischemic Enterocolitis
Chavez, J. A., Chen, W., Frankel, W. L., et al. (2016) · The American Journal of Surgical Pathology · doi:10.1097/pas.0000000000000765 · Cited by 25 · see citing works
Review article: the pharmacological causes of colon ischaemia
Vodusek, Z., Feuerstadt, P., & Brandt, L. J. (2019) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.15052 · Cited by 25 · see citing works
A pragmatic approach to vasculitis in the gastrointestinal tract
Chetty, R., & Serra, S. (2017) · Journal of Clinical Pathology · doi:10.1136/jclinpath-2016-204308 · Cited by 20 · see citing works
Ischemic enterocolitis and its differential diagnosis
Uberti, G., Goldblum, J. R., & Allende, D. S. (2014) · Seminars in Diagnostic Pathology · doi:10.1053/j.semdp.2014.02.001 · Cited by 18 · see citing works
The 4 Quadrants: Acute Pathology in the Abdomen and Current Imaging Guidelines
Mattson, B., & Dulaimy, K. (2017) · Seminars in Ultrasound CT and MRI · doi:10.1053/j.sult.2017.02.006 · Cited by 18 · see citing works
Anatomic and radiologic review of chronic mesenteric ischemia and its treatment
Jaster, A. W., Choudhery, S., Ahn, R. W., Sutphin, P. D., Kalva, S. P., Anderson, M., & Pillai, A. K. (2016) · Clinical Imaging · doi:10.1016/j.clinimag.2016.04.003 · Cited by 16 · see citing works
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Ischemic bowel disease in 2021.
Ahmed, M. (2021) · World Journal of Gastroenterology · doi:10.3748/wjg.v27.i29.4746 · Cited by 77 · see citing works
Review article: the pharmacological causes of colon ischaemia
Vodusek, Z., Feuerstadt, P., & Brandt, L. J. (2019) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.15052 · Cited by 25 · see citing works
- Authors
- Patil, P., & Panarelli, N. C.
- Affiliations
- Albert Einstein College of Medicine (US)
- Corresponding author
- Patil, Priyanka
- Venue
- Academic Pathology
- Publisher
- Elsevier BV
- Published
- 2019-01
- Volume
- 6
- Pages
- 2374289519888709
- ISSN
- 2374-2895 (ISSN-L)
- PMC
- PMC6873276
- OpenAlex
- W2989710933
- Cited by
- 8
- References
- 35
- Citations by year
- 2026: 1 · 2025: 2 · 2023: 1 · 2021: 2 · 2020: 1 · 2018: 1
- FWCI
- 0.72
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Academic Pathology (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Surgery › Abdominal vascular conditions and treatments
- Health Sciences › Medicine › Surgery › Gastrointestinal disorders and treatments
- Health Sciences › Medicine › Family Practice › Clinical Reasoning and Diagnostic Skills
- Keywords
- intestinal ischemia, adult patients, pathology education, disease mechanisms, diagnostic pathology, therapeutic pathology, organ system pathology
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