The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Cognitive findings of an exploratory trial of docosahexaenoic acid and lutein supplementation in older women
Abstract
INTRODUCTION: Low dietary intake of docosahexaenoic acid (DHA) and/or foods rich in lutein may be associated with increased risk of cognitive decline in the elderly. SUBJECTS AND METHODS: The cognitive benefit of DHA and lutein in unimpaired elder women was explored in the context of a 4-month, double-blind, intervention trial of DHA and lutein supplementation for eye health. Forty-nine women (aged 60-80 years) were randomized to receive DHA (800 mg/day; n = 14), lutein (12 mg/day; n = 11), a combination of DHA and lutein (n = 14) or placebo (n = 10). Subjects underwent cognitive tests measuring verbal fluency, memory, processing speed and accuracy, and self-reports of mood at randomization and upon completion of the trial. RESULTS: Following supplementation, verbal fluency scores improved significantly in the DHA, lutein, and combined treatment groups (P < 0.03). Memory scores and rate of learning improved significantly in the combined treatment group (P < 0.03), who also displayed a trend toward more efficient learning (P = 0.07). Measures of mental processing speed, accuracy and mood were not affected by supplementation. CONCLUSIONS: These exploratory findings suggest that DHA and lutein supplementation may have cognitive benefit for older adults.
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Cites
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Consumption of Fish and n-3 Fatty Acids and Risk of Incident Alzheimer Disease
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Cited by
Jomova, K., Alomar, S. Y., Alwasel, S. H., Nepovimova, E., Kuca, K., & Valko, M. (2024) · Archives of Toxicology · doi:10.1007/s00204-024-03696-4 · Cited by 1,445
Omega-3 polyunsaturated fatty acids and their health benefits
Shahidi, F., & Ambigaipalan, P. (2018) · Annual Review of Food Science and Technology · doi:10.1146/annurev-food-111317-095850 · Cited by 1,390
Docosahexaenoic Acid Supplementation and Cognitive Decline in Alzheimer Disease: A Randomized Trial
Quinn, J. F., Raman, R., Thomas, R. G., Yurko-Mauro, K., Nelson, E. B., Van Dyck, C., Galvin, J. E., Emond, J., Jack, C. R., Weiner, M., et al. (2010) · JAMA · doi:10.1001/jama.2010.1510 · Cited by 764
Role of lutein and zeaxanthin in visual and cognitive function throughout the lifespan
Johnson, E. J. (2014) · Nutrition Reviews · doi:10.1111/nure.12133 · Cited by 438
Self-citationDocosahexaenoic Acid and Cognition throughout the Lifespan
Weiser, M., Butt, C., & Mohajeri, M. (2016) · Nutrients · doi:10.3390/nu8020099 · Cited by 400
Metadata
- Authors
- Johnson, E. J., Mcdonald, K., Caldarella, S. M., Chung, H.-Y., Troen, A. M., & Snodderly, D. M.
- Venue
- Nutritional Neuroscience
- Publisher
- Informa UK Limited
- Published
- 2008-04
- Volume
- 11
- Issue
- 2
- Pages
- 75-83
- ISSN
- 1028-415X (ISSN-L)
- 1476-8305
- OpenAlex
- W2030711203
- Cited by
- 291
- References
- 7
- FWCI
- 6.19
- Type
- journal article
- Language
- en
- Open access
- closed
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- Johnson, E. J., Mcdonald, K., Caldarella, S. M., Chung, H.-Y., Troen, A. M., & Snodderly, D. M. (2008). Cognitive findings of an exploratory trial of docosahexaenoic acid and lutein supplementation in older women. Nutritional Neuroscience. https://doi.org/10.1179/147683008x301450
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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