The DOI matches its Crossref record; 81 of the 81 references it cites were found in a registry or an index.
Role of lutein and zeaxanthin in visual and cognitive function throughout the lifespan
Abstract
The relationship between lutein and zeaxanthin and visual and cognitive health throughout the lifespan is compelling. There is a variety of evidence to support a role for lutein and zeaxanthin in vision. Lutein's role in cognition has only recently been considered. Lutein and its isomer, zeaxanthin, are taken up selectively into eye tissue. Lutein is the predominant carotenoid in human brain tissue. Lutein and zeaxanthin in neural tissue may have biological effects that include antioxidation, anti-inflammation, and structural actions. In addition, lutein and zeaxanthin may be protective against eye disease because they absorb damaging blue light that enters the eye. In pediatric brains, the relative contribution of lutein to the total carotenoids is twice that found in adults, accounting for more than half the concentration of total carotenoids. The greater proportion of lutein in the pediatric brain suggests a need for lutein during neural development as well. In adults, higher lutein status is related to better cognitive performance, and lutein supplementation improves cognition. The evidence to date warrants further investigation into the role of lutein and zeaxanthin in visual and cognitive health throughout the lifespan.
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Self-citationA Structural MRI Study of Human Brain Development from Birth to 2 Years
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Cited by
Wallace, T. C., Bailey, R. L., Blumberg, J. B., Burton-Freeman, B., Chen, C.-Y. O., Crowe-White, K. M., Drewnowski, A., Hooshmand, S., Johnson, E., Lewis, R., et al. (2020) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2019.1632258 · Cited by 638
Self-citationThe Potential and Challenge of Microalgae as Promising Future Food Sources
Chen, C., Tang, T., Shi, Q., Zhou, Z., & Fan, J. (2022) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2022.06.016 · Cited by 229
Moran, N. E., Mohn, E. S., Hason, N., Erdman, J. W., & Johnson, E. J. (2018) · Advances in Nutrition · doi:10.1093/advances/nmy025 · Cited by 205
Self-citationHealth Effects of Carotenoids during Pregnancy and Lactation
Zielińska, M., Wesołowska, A., Pawlus, B., & Hamułka, J. (2017) · Nutrients · doi:10.3390/nu9080838 · Cited by 111
Lutein and Zeaxanthin Influence Brain Function in Older Adults: A Randomized Controlled Trial
Lindbergh, C. A., Renzi-Hammond, L. M., Hammond, B. R., Terry, D. P., Mewborn, C. M., Puente, A. N., & Miller, L. S. (2018) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617717000534 · Cited by 94
Metadata
- Authors
- Johnson, E. J.
- Venue
- Nutrition Reviews
- Publisher
- Oxford University Press (OUP)
- Published
- 2014-08-08
- Volume
- 72
- Issue
- 9
- Pages
- 605-612
- ISSN
- 0029-6643 (ISSN-L)
- OpenAlex
- W2144708187
- Cited by
- 438
- References
- 81
- FWCI
- 13.37
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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