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Methylene Blue - a Therapeutic Dye for All Seasons?
Abstract
Since it was first synthesised in 1876, Methylene Blue (MB) has found uses in many different areas of clinical medicine, ranging from dementia to cancer chemotherapy. In addition, MB formed the basis of antimicrobial chemotherapy--particularly in the area of antimalarials--and eventually led to the discovery of the neuroleptic drug families. More recently, the photosensitising potential of MB and its congeners has been recognised, and these are being applied in various antimicrobial fields, especially that of blood disinfection. The range of activities of MB is due to the combination of its simple chemical structure and facility for oxidation-reduction reactions in situ.
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Cited by
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Souza, R. C., Junqueira, J. C., Rossoni, R. D., Pereira, C. A., Munin, E., & Jorge, A. O. C. (2010) · Lasers in Medical Science · doi:10.1007/s10103-009-0706-z · Cited by 167
Aminothienopyridazines and methylene blue affect Tau fibrillization via cysteine oxidation
Crowe, A., James, M. J., Lee, V. M.-Y., Smith, A. B., Trojanowski, J. Q., Ballatore, C., & Brunden, K. R. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.436006 · Cited by 143
Mitochondrial Targeted Antioxidant in Cerebral Ischemia
Ahmed, E., Donovan, T., Yujiao, L., & Zhang, Q. (2015) · Journal of Neurology and Neuroscience · doi:10.21767/2171-6625.100017 · Cited by 38
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Metadata
- Authors
- Wainwright, M., & Crossley, K. B.
- Venue
- Journal of Chemotherapy
- Publisher
- Informa UK Limited
- Published
- 2002-01
- Volume
- 14
- Issue
- 5
- Pages
- 431-443
- ISSN
- 1120-009X (ISSN-L)
- 1973-9478
- OpenAlex
- W2024077985
- Cited by
- 396
- References
- 0
- FWCI
- 3.65
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
