The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Unresolved questions, changing definitions, and novel paradigms for defining endothelial progenitor cells
Open accessAbstract
The field of vascular biology has been stimulated by the concept that circulating endothelial progenitor cells (EPCs) may play a role in neoangiogenesis (postnatal vasculogenesis). One problem for the field has been the difficulty in accurately defining an EPC. Likewise, circulating endothelial cells (CECs) are not well defined. The lack of a detailed understanding of the proliferative potential of EPCs and CECs has contributed to the controversy in identifying these cells and understanding their biology in vitro or in vivo. A novel paradigm using proliferative potential as one defining aspect of EPC biology suggests that a hierarchy of EPCs exists in human blood and blood vessels. The potential implications of this view in relation to current EPC definitions are discussed.
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Cites
Angiogenesis in cancer and other diseases
Carmeliet, P., & Jain, R. K. (2000) · Nature · doi:10.1038/35025220 · Cited by 9,070
Isolation of Putative Progenitor Endothelial Cells for Angiogenesis
Asahara, T., Murohara, T., Sullivan, A., Silver, M., van der Zee, R., Li, T., Witzenbichler, B., Schatteman, G., & Isner, J. M. (1997) · Science · doi:10.1126/science.275.5302.964 · Cited by 8,725
Tumorigenesis and the angiogenic switch
Bergers, G., & Benjamin, L. E. (2003) · Nature reviews. Cancer · doi:10.1038/nrc1093 · Cited by 3,559
Circulating endothelial progenitor cells, vascular function, and cardiovascular risk
Hill, J. M., Zalos, G., Halcox, J. P. J., Schenke, W. H., Waclawiw, M. A., Quyyumi, A. A., & Finkel, T. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa022287 · Cited by 3,423
Functional plasticity of macrophages: reversible adaptation to changing microenvironments
Stout, R. D., & Suttles, J. (2004) · Journal of Leukocyte Biology · doi:10.1189/jlb.0504272 · Cited by 751
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Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper
Lener, T., Gimona, M., Aigner, L., Börger, V., Buzas, E., Camussi, G., Chaput, N., Chatterjee, D., Court, F. A., del Portillo, H. A., et al. (2015) · Journal of Extracellular Vesicles · doi:10.3402/jev.v4.30087 · Cited by 1,491
Concise Review: Circulating Endothelial Progenitor Cells for Vascular Medicine
Asahara, T., Kawamoto, A., & Masuda, H. (2011) · Stem Cells · doi:10.1002/stem.745 · Cited by 411
Endothelial Outgrowth Cells Are Not Derived From CD133 + Cells or CD45 + Hematopoietic Precursors
Timmermans, F., Van Hauwermeiren, F., De Smedt, M., Raedt, R., Plasschaert, F., De Buyzere, M. L., Gillebert, T. C., Plum, J., & Vandekerckhove, B. (2007) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.107.144972 · Cited by 355
Hur, J., Yang, H.-M., Yoon, C.-H., Lee, C.-S., Park, K.-W., Kim, J.-H., Kim, T.-Y., Kim, J.-Y., Kang, H.-J., Chae, I.-H., et al. (2007) · Circulation · doi:10.1161/circulationaha.107.694778 · Cited by 255
Fadini, G. P., Coracina, A., Baesso, I., Agostini, C., Tiengo, A., Avogaro, A., & Vigili de Kreutzenberg, S. (2006) · Stroke · doi:10.1161/01.str.0000236064.19293.79 · Cited by 205
Metadata
- Authors
- Ingram, D. A., Caplice, N. M., & Yoder, M. C.
- Venue
- Blood
- Publisher
- American Society of Hematology
- Published
- 2005-09-01
- Volume
- 106
- Issue
- 5
- Pages
- 1525-1531
- ISSN
- 0006-4971 (ISSN-L)
- 1528-0020
- OpenAlex
- W2052488548
- Cited by
- 442
- References
- 5
- FWCI
- 13.48
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Ingram, D. A., Caplice, N. M., & Yoder, M. C. (2005). Unresolved questions, changing definitions, and novel paradigms for defining endothelial progenitor cells. Blood. https://doi.org/10.1182/blood-2005-04-1509
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
